-
1
-
-
0026874127
-
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
-
1. American College of Chest Physicians/ Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992; 20:864-874
-
(1992)
Crit Care Med
, vol.20
, pp. 864-874
-
-
-
3
-
-
0026766175
-
Modulators of coagulation: A critical appraisal of their role in sepsis
-
3. Bone RC: Modulators of coagulation: A critical appraisal of their role in sepsis. Arch Intern Med 1992; 152:1381-1389
-
(1992)
Arch Intern Med
, vol.152
, pp. 1381-1389
-
-
Bone, R.C.1
-
4
-
-
0031057343
-
The cytokine-mediated imbalance between coagulant and anticoagulant mechanisms in sepsis and endotoxaemia
-
4. Levi M, van der Poll T, ten Cate H, et al: The cytokine-mediated imbalance between coagulant and anticoagulant mechanisms in sepsis and endotoxaemia. Eur J Clin Invest 1997; 27:3-9
-
(1997)
Eur J Clin Invest
, vol.27
, pp. 3-9
-
-
Levi, M.1
Van Der Poll, T.2
Ten Cate, H.3
-
6
-
-
0026534242
-
Septic shock, multiple organ failure, and disseminated intravascular coagulation: Compared patterns of antithrombin III, protein C, and protein S deficiencies
-
6. Fourrier F, Chopin C, Goudemand J, et al: Septic shock, multiple organ failure, and disseminated intravascular coagulation: Compared patterns of antithrombin III, protein C, and protein S deficiencies. Chest 1992; 101: 816-823
-
(1992)
Chest
, vol.101
, pp. 816-823
-
-
Fourrier, F.1
Chopin, C.2
Goudemand, J.3
-
7
-
-
0028127109
-
Study of the balance between coagulation and fibrinolysis in disseminated intravascular coagulation using molecular markers
-
7. Asakura H, Jokaji H, Saito M, et al: Study of the balance between coagulation and fibrinolysis in disseminated intravascular coagulation using molecular markers. Blood Coagul Fibrinolysis 1994; 5:829-832
-
(1994)
Blood Coagul Fibrinolysis
, vol.5
, pp. 829-832
-
-
Asakura, H.1
Jokaji, H.2
Saito, M.3
-
8
-
-
0020063793
-
Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C
-
8. Esmon NL, Owen WG, Esmon CT: Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C. J Biol Chem 1982; 257:859-864
-
(1982)
J Biol Chem
, vol.257
, pp. 859-864
-
-
Esmon, N.L.1
Owen, W.G.2
Esmon, C.T.3
-
9
-
-
0020072618
-
Mechanism of action of human activated protein C, a thrombin-dependent anticoagulant enzyme
-
9. Marlar RA, Kleiss AJ, Griffin JH: Mechanism of action of human activated protein C, a thrombin-dependent anticoagulant enzyme. Blood 1982; 59:1067-1072
-
(1982)
Blood
, vol.59
, pp. 1067-1072
-
-
Marlar, R.A.1
Kleiss, A.J.2
Griffin, J.H.3
-
10
-
-
0029790055
-
The endothelial protein C receptor augments protein C activation by the thrombin-thrombomodulin complex
-
10. Stearns-Kurosawa DJ, Kurosawa S, Mollica JS, et al: The endothelial protein C receptor augments protein C activation by the thrombin-thrombomodulin complex. Proc Natl Acad Sci U S A 1996; 93:10212-10216
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 10212-10216
-
-
Stearns-Kurosawa, D.J.1
Kurosawa, S.2
Mollica, J.S.3
-
11
-
-
0023089665
-
Endotoxin enhances tissue factor and suppresses thrombomodulin expression of human vascular endothelium in vitro
-
11. Moore KL, Andreoli SP, Esmon NL, et al: Endotoxin enhances tissue factor and suppresses thrombomodulin expression of human vascular endothelium in vitro. J Clin Invest 1987; 79:124-130
-
(1987)
J Clin Invest
, vol.79
, pp. 124-130
-
-
Moore, K.L.1
Andreoli, S.P.2
Esmon, N.L.3
-
12
-
-
0022601049
-
Modulation of endothelial cell hemostatic properties by tumor necrosis factor
-
12. Nawroth PP, Stern DM: Modulation of endothelial cell hemostatic properties by tumor necrosis factor. J Exp Med 1986; 163: 740-745
-
(1986)
J Exp Med
, vol.163
, pp. 740-745
-
-
Nawroth, P.P.1
Stern, D.M.2
-
13
-
-
0023755932
-
Tumor necrosis factor suppresses transcription of the thrombomodulin gene in endothelial cells
-
13. Conway EM, Rosenberg RD: Tumor necrosis factor suppresses transcription of the thrombomodulin gene in endothelial cells. Mol Cell Biol 1988; 8:5588-5592
-
(1988)
Mol Cell Biol
, vol.8
, pp. 5588-5592
-
-
Conway, E.M.1
Rosenberg, R.D.2
-
14
-
-
2442724586
-
Interleukin 1 induces endothelial cell procoagulant while suppressing cell-surface anti-coagulant activity
-
14. Nawroth PP, Handley DA, Esmon CT, et al: Interleukin 1 induces endothelial cell procoagulant while suppressing cell-surface anti-coagulant activity. Proc Natl Acad Sci U S A 1986; 83:3460-3464
-
(1986)
Proc Natl Acad Sci U S A
, vol.83
, pp. 3460-3464
-
-
Nawroth, P.P.1
Handley, D.A.2
Esmon, C.T.3
-
15
-
-
0023122016
-
Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboons
-
15. Taylor FB Jr, Chang A, Esmon CT, et al: Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboons. J Clin Invest 1987; 79:918-925
-
(1987)
J Clin Invest
, vol.79
, pp. 918-925
-
-
Taylor F.B., Jr.1
Chang, A.2
Esmon, C.T.3
-
16
-
-
0024419991
-
Quantitative relation between plasma endotoxin, antithrombin, protein C, extrinsic coagulation pathway inhibitor and fibrinopeptide A in systemic meningococcal disease
-
16. Brandtzaeg P, Sandset PM, Joe GB, et al: Quantitative relation between plasma endotoxin, antithrombin, protein C, extrinsic coagulation pathway inhibitor and fibrinopeptide A in systemic meningococcal disease. Thromb Res 1989; 55:459-470
-
(1989)
Thromb Res
, vol.55
, pp. 459-470
-
-
Brandtzaeg, P.1
Sandset, P.M.2
Joe, G.B.3
-
17
-
-
0027214771
-
Time course of hemostatic abnormalities in sepsis and its relation to outcome
-
17. Lorente JA, Garcia-Frade LJ, Landin L, et al: Time course of hemostatic abnormalities in sepsis and its relation to outcome. Chest 1993; 103:1536-1542
-
(1993)
Chest
, vol.103
, pp. 1536-1542
-
-
Lorente, J.A.1
Garcia-Frade, L.J.2
Landin, L.3
-
18
-
-
0027289342
-
Management of fever in patients with cancer and treatment-induced neutropenia
-
18. Pizzo PA: Management of fever in patients with cancer and treatment-induced neutropenia. N Engl J Med 1993; 328:1323-1332
-
(1993)
N Engl J Med
, vol.328
, pp. 1323-1332
-
-
Pizzo, P.A.1
-
19
-
-
0029743427
-
Factor VIIa and antithrombin III activity during severe sepsis and septic shock in neutropenic patients
-
19. Mesters RM, Mannucci PM, Coppola R, et al: Factor VIIa and antithrombin III activity during severe sepsis and septic shock in neutropenic patients. Blood 1996; 88:881-886
-
(1996)
Blood
, vol.88
, pp. 881-886
-
-
Mesters, R.M.1
Mannucci, P.M.2
Coppola, R.3
-
20
-
-
0026630953
-
Direct detection of activated protein C in blood from human subjects
-
20. Gruber A, Griffin JH: Direct detection of activated protein C in blood from human subjects. Blood 1992; 79:2340-2348
-
(1992)
Blood
, vol.79
, pp. 2340-2348
-
-
Gruber, A.1
Griffin, J.H.2
-
22
-
-
0028840297
-
Multiple organ dysfunction syndrome in bone marrow transplantation
-
22. Haire WD, Ruby EI, Gordon BG, et al: Multiple organ dysfunction syndrome in bone marrow transplantation. JAMA 1995; 274: 1289-1295
-
(1995)
JAMA
, vol.274
, pp. 1289-1295
-
-
Haire, W.D.1
Ruby, E.I.2
Gordon, B.G.3
-
23
-
-
0027225620
-
Naturally occurring anticoagulants and bone marrow transplantation: Plasma protein C predicts the development of venocclusive disease of the liver
-
23. Faioni EM, Krachmalnicoff A, Bearman SI, et al: Naturally occurring anticoagulants and bone marrow transplantation: Plasma protein C predicts the development of venocclusive disease of the liver. Blood 1993; 81: 3458-3462
-
(1993)
Blood
, vol.81
, pp. 3458-3462
-
-
Faioni, E.M.1
Krachmalnicoff, A.2
Bearman, S.I.3
-
24
-
-
0029030147
-
Trauma, sepsis and disseminated intravascular coagulation
-
24. Hardaway RM: Trauma, sepsis and disseminated intravascular coagulation. J Intensive Care Med 1995; 10:145-152
-
(1995)
J Intensive Care Med
, vol.10
, pp. 145-152
-
-
Hardaway, R.M.1
-
25
-
-
0029119879
-
An update on clinical and basic aspects of the protein C anti-coagulant pathway
-
25. Esmon CT, Schwarz HP: An update on clinical and basic aspects of the protein C anti-coagulant pathway. Trends Cardiovasc Med 1995; 5:141-148
-
(1995)
Trends Cardiovasc Med
, vol.5
, pp. 141-148
-
-
Esmon, C.T.1
Schwarz, H.P.2
-
26
-
-
0001748803
-
Antithrombotic and anti-inflammatory agents of the protein C anticoagulant pathway
-
26. Yan SB, Grinnell BW: Antithrombotic and anti-inflammatory agents of the protein C anticoagulant pathway. Ann Rep Med Chem 1994; 11:103-112
-
(1994)
Ann Rep Med Chem
, vol.11
, pp. 103-112
-
-
Yan, S.B.1
Grinnell, B.W.2
-
28
-
-
0026409651
-
Treatment of homozygous protein C deficiency and neonatal purpura fulminans with a purified protein C concentrate
-
28. Dreyfus M, Magny JF, Bridey F, et al: Treatment of homozygous protein C deficiency and neonatal purpura fulminans with a purified protein C concentrate. N Engl J Med 1991; 325:1565-1568
-
(1991)
N Engl J Med
, vol.325
, pp. 1565-1568
-
-
Dreyfus, M.1
Magny, J.F.2
Bridey, F.3
-
29
-
-
0027965649
-
Physiological anticoagulation. Resistance to activated protein C and venous thromboembolism
-
29. Dahlbäck B: Physiological anticoagulation. Resistance to activated protein C and venous thromboembolism. J Clin Invest 1994; 94: 923-927
-
(1994)
J Clin Invest
, vol.94
, pp. 923-927
-
-
Dahlbäck, B.1
-
30
-
-
0027973305
-
Cytokine response to infection in patients with acute myelogenous leukaemia following intensive chemotherapy
-
30. Ostermann H, Rothenburger M, Mesters RM, et al: Cytokine response to infection in patients with acute myelogenous leukaemia following intensive chemotherapy. Br J Haematol 1994; 88:332-337
-
(1994)
Br J Haematol
, vol.88
, pp. 332-337
-
-
Ostermann, H.1
Rothenburger, M.2
Mesters, R.M.3
-
31
-
-
0021863658
-
Serial studies of protein C and its plasma inhibitor in patients with disseminated intravascular coagulation
-
31. Marlar RA, Endres-Brooks J, Miller C: Serial studies of protein C and its plasma inhibitor in patients with disseminated intravascular coagulation. Blood 1985; 66:59-63
-
(1985)
Blood
, vol.66
, pp. 59-63
-
-
Marlar, R.A.1
Endres-Brooks, J.2
Miller, C.3
-
32
-
-
0023184343
-
Purpura fulminans in meningococcemia: Association with acquired deficiencies of protein C and S
-
32. Powars DR, Rogers ZR, Patch MJ, et al: Purpura fulminans in meningococcemia: Association with acquired deficiencies of protein C and S. N Engl J Med 1987; 317:571-572
-
(1987)
N Engl J Med
, vol.317
, pp. 571-572
-
-
Powars, D.R.1
Rogers, Z.R.2
Patch, M.J.3
-
33
-
-
0026061609
-
Protein C, protein S and C4b-binding protein in severe infection and septic shock
-
33. Hesselvik JF, Malm J, Dahlbäck B, et al: Protein C, protein S and C4b-binding protein in severe infection and septic shock. Thromb Haemost 1991; 65:126-129
-
(1991)
Thromb Haemost
, vol.65
, pp. 126-129
-
-
Hesselvik, J.F.1
Malm, J.2
Dahlbäck, B.3
-
34
-
-
0026788072
-
Protein C and S deficiency in severe infectious purpura of children: A collaborative study of 40 cases
-
34. Leclerc F, Hazelzet J, Jude B, et al: Protein C and S deficiency in severe infectious purpura of children: A collaborative study of 40 cases. Intensive Care Med 1992; 18:202-205
-
(1992)
Intensive Care Med
, vol.18
, pp. 202-205
-
-
Leclerc, F.1
Hazelzet, J.2
Jude, B.3
-
35
-
-
0026625080
-
Protein C, protein S and C4b-binding protein in neonatal severe infection and septic shock
-
35. Roman J, Velasco F, Fernandez F, et al: Protein C, protein S and C4b-binding protein in neonatal severe infection and septic shock. J Perinat Med 1992; 20:111-116
-
(1992)
J Perinat Med
, vol.20
, pp. 111-116
-
-
Roman, J.1
Velasco, F.2
Fernandez, F.3
-
36
-
-
0027248914
-
Epidemic meningococcemia and purpura fulminans with induced protein C deficiency
-
36. Powars D, Larsen R, Johnson J, et al: Epidemic meningococcemia and purpura fulminans with induced protein C deficiency. Clin Infect Dis 1993; 17:254-261
-
(1993)
Clin Infect Dis
, vol.17
, pp. 254-261
-
-
Powars, D.1
Larsen, R.2
Johnson, J.3
-
37
-
-
0028359396
-
Relation between cytokines and routine laboratory data in children with septic shock and purpura
-
37. Hazelzet JA, van der Voort E, Lindemans J, et al: Relation between cytokines and routine laboratory data in children with septic shock and purpura. Intensive Care Med 1994; 20: 371-374
-
(1994)
Intensive Care Med
, vol.20
, pp. 371-374
-
-
Hazelzet, J.A.1
Van Der Voort, E.2
Lindemans, J.3
-
38
-
-
0028855106
-
Coagulation activation and tissue necrosis in meningococcal septic shock: Severely reduced protein C levels predict a high mortality
-
38. Fijnvandraat K, Derkx B, Peters M, et al: Coagulation activation and tissue necrosis in meningococcal septic shock: Severely reduced protein C levels predict a high mortality. Thromb Haemost 1995; 73:15-20
-
(1995)
Thromb Haemost
, vol.73
, pp. 15-20
-
-
Fijnvandraat, K.1
Derkx, B.2
Peters, M.3
-
39
-
-
0029011240
-
Activation of the protein C pathway in acute sepsis
-
39. Alcaraz A, Espana F, Sanchez-Cuenaca J, et al: Activation of the protein C pathway in acute sepsis. Thromb Res 1995; 79:83-93
-
(1995)
Thromb Res
, vol.79
, pp. 83-93
-
-
Alcaraz, A.1
Espana, F.2
Sanchez-Cuenaca, J.3
-
40
-
-
0021707112
-
Radioimmunoassays for protein C and factor X: Plasma antigen levels in abnormal hemostatic states
-
40. Epstein DJ, Bergum PW, Bajaj SP, et al: Radioimmunoassays for protein C and factor X: Plasma antigen levels in abnormal hemostatic states. Am J Clin Pathol 1984; 82: 573-581
-
(1984)
Am J Clin Pathol
, vol.82
, pp. 573-581
-
-
Epstein, D.J.1
Bergum, P.W.2
Bajaj, S.P.3
-
41
-
-
0025244937
-
Neonatal purpura fulminans due to homozygous protein C-or protein S deficiencies
-
41. Marlar RA, Neumann A: Neonatal purpura fulminans due to homozygous protein C-or protein S deficiencies. Semin Thromb Haemost 1990; 16:299-309
-
(1990)
Semin Thromb Haemost
, vol.16
, pp. 299-309
-
-
Marlar, R.A.1
Neumann, A.2
-
42
-
-
0009465879
-
Upregulation of the message for rodent endothelial cell protein C receptor (EPCR) by endotoxin and thrombin
-
42. Ding W, Gu J-M, Fukudome K, et al: Upregulation of the message for rodent endothelial cell protein C receptor (EPCR) by endotoxin and thrombin. Abstr. Circulation 1996; 94:1-694
-
(1996)
Abstr. Circulation
, vol.94
, pp. 1-694
-
-
Ding, W.1
Gu, J.-M.2
Fukudome, K.3
-
43
-
-
0031973176
-
Plasma levels of endothelial cell protein C receptor are elevated in patients with sepsis and systemic lupus erythematosus: Lack of correlation with thrombomodulin suggests involvement of different pathological processes
-
43. Kurosawa S, Stearns-Kurosawa DJ, Carson CW, et al: Plasma levels of endothelial cell protein C receptor are elevated in patients with sepsis and systemic lupus erythematosus: Lack of correlation with thrombomodulin suggests involvement of different pathological processes. Blood 1998; 91:725-727
-
(1998)
Blood
, vol.91
, pp. 725-727
-
-
Kurosawa, S.1
Stearns-Kurosawa, D.J.2
Carson, C.W.3
-
44
-
-
0024502137
-
Activation and complexation of protein C and cleavage and decrease of protein s in plasma of patients with intravascular coagulation
-
44. Heeb MJ, Mosher D, Griffin JH: Activation and complexation of protein C and cleavage and decrease of protein S in plasma of patients with intravascular coagulation. Blood 1989; 73:455-461
-
(1989)
Blood
, vol.73
, pp. 455-461
-
-
Heeb, M.J.1
Mosher, D.2
Griffin, J.H.3
-
45
-
-
0025119274
-
Determination of plasma protein C inhibitor and of two activated protein C-inhibitor complexes in normals and in patients with intra-vascular coagulation and thrombotic disease
-
45. Espana F, Vicente V, Tabernero D, et al: Determination of plasma protein C inhibitor and of two activated protein C-inhibitor complexes in normals and in patients with intra-vascular coagulation and thrombotic disease. Thromb Res 1990; 59:593-608
-
(1990)
Thromb Res
, vol.59
, pp. 593-608
-
-
Espana, F.1
Vicente, V.2
Tabernero, D.3
-
46
-
-
0025301848
-
A qualitative and quantitative analysis of the activation and inactivation of protein C in vivo in a primate model
-
46. Hoogendoorn H, Nesheim ME, Giles AR: A qualitative and quantitative analysis of the activation and inactivation of protein C in vivo in a primate model. Blood 1990; 75: 2164-2171
-
(1990)
Blood
, vol.75
, pp. 2164-2171
-
-
Hoogendoorn, H.1
Nesheim, M.E.2
Giles, A.R.3
-
47
-
-
0027273931
-
2-macroglobulin, in patients with disseminated intravascular coagulation
-
2-macroglobulin, in patients with disseminated intravascular coagulation. Thromb Haemost 1993; 69:448-453
-
(1993)
Thromb Haemost
, vol.69
, pp. 448-453
-
-
Scully, M.F.1
Toh, C.H.2
Hoogendoorn, H.3
-
48
-
-
0024589205
-
Tumor necrosis factor leads to the internalization and degradation of thrombomodulin from the surface of bovine aortic endothelial cells in culture
-
48. Moore KL, Esmon CT, Esmon NL: Tumor necrosis factor leads to the internalization and degradation of thrombomodulin from the surface of bovine aortic endothelial cells in culture. Blood 1989; 73:159-165
-
(1989)
Blood
, vol.73
, pp. 159-165
-
-
Moore, K.L.1
Esmon, C.T.2
Esmon, N.L.3
-
49
-
-
0027725139
-
Expression of tissue factor, thrombomodulin, and E-selectin in baboons with lethal Escherichia coli sepsis
-
49. Drake TA, Cheng J, Chang A, et al: Expression of tissue factor, thrombomodulin, and E-selectin in baboons with lethal Escherichia coli sepsis. Am J Pathol 1993; 142: 1458-1470
-
(1993)
Am J Pathol
, vol.142
, pp. 1458-1470
-
-
Drake, T.A.1
Cheng, J.2
Chang, A.3
-
51
-
-
0025710312
-
Increase in national hospital discharge survey rates for septicemia - United States. 1979-1987
-
51. Increase in national hospital discharge survey rates for septicemia - United States. 1979-1987. MMWR Morb Mortal Wkly Rep 1990; 39:31-34
-
(1990)
MMWR Morb Mortal Wkly Rep
, vol.39
, pp. 31-34
-
-
-
52
-
-
0029401567
-
The Italian sepsis study: Preliminary results on the incidence and evolution of SIRS, sepsis, severe sepsis and septic shock
-
52. Salvo I, de Cian W, Musicco M, et al: The Italian sepsis study: Preliminary results on the incidence and evolution of SIRS, sepsis, severe sepsis and septic shock. Intensive Care Med 1995; 21:S244-S249
-
(1995)
Intensive Care Med
, vol.21
-
-
Salvo, I.1
De Cian, W.2
Musicco, M.3
-
53
-
-
0028557981
-
Treatment of septic shock with human monoclonal antibody HA-1A. A randomized, double-blind, placebo-controlled trial. CHESS trial study group
-
53. McCloskey RV, Straube RC, Sanders C, et al: Treatment of septic shock with human monoclonal antibody HA-1A. A randomized, double-blind, placebo-controlled trial. CHESS trial study group. Ann Intern Med 1994; 121:1-5
-
(1994)
Ann Intern Med
, vol.121
, pp. 1-5
-
-
McCloskey, R.V.1
Straube, R.C.2
Sanders, C.3
-
54
-
-
0029043636
-
A second large controlled clinical study of E5, a monoclonal antibody to endotoxin: Results of a prospective, multicenter, randomized, controlled trial. The E5 sepsis study group
-
54. Bone RC, Balk RA, Fein AM, et al: A second large controlled clinical study of E5, a monoclonal antibody to endotoxin: Results of a prospective, multicenter, randomized, controlled trial. The E5 sepsis study group. Crit Care Med 1996; 23:994-1006
-
(1996)
Crit Care Med
, vol.23
, pp. 994-1006
-
-
Bone, R.C.1
Balk, R.A.2
Fein, A.M.3
-
55
-
-
0028239555
-
Recombinant human interleukin 1 receptor antagonist in the treatment of patients with sepsis syndrome
-
55. Fisher CJ, Dhainaut JA, Opal SM, et al: Recombinant human interleukin 1 receptor antagonist in the treatment of patients with sepsis syndrome. JAMA 1994; 271:1836-1843
-
(1994)
JAMA
, vol.271
, pp. 1836-1843
-
-
Fisher, C.J.1
Dhainaut, J.A.2
Opal, S.M.3
-
56
-
-
23444446083
-
Selected treatment strategies for septic shock based on proposed mechanisms of pathogenesis
-
56. Natanson C, Hoffman WD, Suffredini AF, et al: Selected treatment strategies for septic shock based on proposed mechanisms of pathogenesis. Ann Intern Med 1994; 120: 771-783
-
(1994)
Ann Intern Med
, vol.120
, pp. 771-783
-
-
Natanson, C.1
Hoffman, W.D.2
Suffredini, A.F.3
-
57
-
-
0029900294
-
Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein
-
57. Fisher CJ, Agosti JM, Opal SM, et al: Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein. N Engl J Med 1996; 334:1697-1702
-
(1996)
N Engl J Med
, vol.334
, pp. 1697-1702
-
-
Fisher, C.J.1
Agosti, J.M.2
Opal, S.M.3
-
58
-
-
9344246862
-
Assessment of the safety and efficacy of the monoclonal anti-tumor necrosis factor antibody-fragment, MAK 195F, in patients with sepsis and septic shock: A multicenter, randomized, placebo-controlled, dose-ranging study
-
58. Reinhart K, Wiegand-Lohnert C, Grimminger F, et al: Assessment of the safety and efficacy of the monoclonal anti-tumor necrosis factor antibody-fragment, MAK 195F, in patients with sepsis and septic shock: A multicenter, randomized, placebo-controlled, dose-ranging study. Crit Care Med 1996; 24: 733-742
-
(1996)
Crit Care Med
, vol.24
, pp. 733-742
-
-
Reinhart, K.1
Wiegand-Lohnert, C.2
Grimminger, F.3
-
59
-
-
0030746482
-
Anti-inflammatory therapies to treat sepsis and septic shock: A reassessment
-
59. Zeni F, Freeman B, Natanson C: Anti-inflammatory therapies to treat sepsis and septic shock: A reassessment. Crit Care Med 1997; 25:1095-1100
-
(1997)
Crit Care Med
, vol.25
, pp. 1095-1100
-
-
Zeni, F.1
Freeman, B.2
Natanson, C.3
-
60
-
-
17044458176
-
Effect of a recombinant dimeric tumor necrosis factor receptor on inflammatory responses to intravenous endotoxin in normal humans
-
60. Van der Poll T, Coyle SM, Levi M, et al: Effect of a recombinant dimeric tumor necrosis factor receptor on inflammatory responses to intravenous endotoxin in normal humans. Blood 1997; 89:3727-3734
-
(1997)
Blood
, vol.89
, pp. 3727-3734
-
-
Van Der Poll, T.1
Coyle, S.M.2
Levi, M.3
-
61
-
-
0024451060
-
Efficacy of antithrombin III supplementation in animal models of fulminant Escherichia coli endotoxemia or bacteremia
-
61. Emerson TE, Fournel MA, Redens TB, et al: Efficacy of antithrombin III supplementation in animal models of fulminant Escherichia coli endotoxemia or bacteremia. Am J Med 1989; 87(Suppl 3b):27-35
-
(1989)
Am J Med
, vol.87
, Issue.SUPPL. 3B
, pp. 27-35
-
-
Emerson, T.E.1
Fournel, M.A.2
Redens, T.B.3
-
62
-
-
0027319678
-
Tissue factor pathway inhibitor reduces mortality from Escherichia coli septic shock
-
62. Creasey AA, Chang ACK, Feigen L, et al: Tissue factor pathway inhibitor reduces mortality from Escherichia coli septic shock. J Clin Invest 1993; 91:2850-2860
-
(1993)
J Clin Invest
, vol.91
, pp. 2850-2860
-
-
Creasey, A.A.1
Chang, A.C.K.2
Feigen, L.3
-
63
-
-
0029855166
-
Increase of plasminogen activator inhibitor levels predicts outcome of leukocytopenic patients with sepsis
-
63. Mesters RM, Flörke, Ostermann H, et al: Increase of plasminogen activator inhibitor levels predicts outcome of leukocytopenic patients with sepsis. Thromb Haemost 75: 902-907
-
Thromb Haemost
, vol.75
, pp. 902-907
-
-
Mesters, R.M.1
Flörke2
Ostermann, H.3
-
64
-
-
0027367126
-
Selective effects of protein C on activation of human monocytes by lipopolysaccharide, interferon-gamma, or PMA: Modulation of effects on CD11b and CD14 but not CD25 or CD54 induction
-
64. Grey T, Hau H, Salem HH, et al: Selective effects of protein C on activation of human monocytes by lipopolysaccharide, interferon-gamma, or PMA: Modulation of effects on CD11b and CD14 but not CD25 or CD54 induction. Transplant Proc 1993; 25: 2913-2914
-
(1993)
Transplant Proc
, vol.25
, pp. 2913-2914
-
-
Grey, T.1
Hau, H.2
Salem, H.H.3
-
65
-
-
0029873131
-
A physiologic anti-inflammatory pathway based on thrombomodulin expression and generation of activated protein C by human mononuclear phagocytes
-
65. Grey ST, Hancock WW: A physiologic anti-inflammatory pathway based on thrombomodulin expression and generation of activated protein C by human mononuclear phagocytes. J Immunol 1996; 156: 2256-2263
-
(1996)
J Immunol
, vol.156
, pp. 2256-2263
-
-
Grey, S.T.1
Hancock, W.W.2
-
66
-
-
0025835094
-
C4b-binding protein exacerbates the host response to Escherichia coli
-
66. Taylor FB Jr, Chang A, Ferrell G, et al: C4b-binding protein exacerbates the host response to Escherichia coli. Blood 1991; 78: 357-363
-
(1991)
Blood
, vol.78
, pp. 357-363
-
-
Taylor F.B., Jr.1
Chang, A.2
Ferrell, G.3
-
67
-
-
0030034186
-
Activated protein C attenuates endotoxin-induced pulmonary vascular injury by inhibiting activated leukocytes in rats
-
67. Murakami K, Okajima K, Uchiba M, et al: Activated protein C attenuates endotoxin-induced pulmonary vascular injury by inhibiting activated leukocytes in rats. Thromb Haemost 1996; 87:642-647
-
(1996)
Thromb Haemost
, vol.87
, pp. 642-647
-
-
Murakami, K.1
Okajima, K.2
Uchiba, M.3
-
68
-
-
0031989122
-
Activated protein C concentrate for the treatment of meningococcal endotoxin shock in rabbits
-
68. Roback MG, Stack AM, Thompson C, et al: Activated protein C concentrate for the treatment of meningococcal endotoxin shock in rabbits. Shock 1998; 9:138-142
-
(1998)
Shock
, vol.9
, pp. 138-142
-
-
Roback, M.G.1
Stack, A.M.2
Thompson, C.3
-
69
-
-
0027397621
-
Severe acquired protein C deficiency in purpura fulminans associated with disseminated intravascular coagulation: Treatment with protein C concentrate
-
69. Gerson WT, Dickerman JD, Bovill EG, et al: Severe acquired protein C deficiency in purpura fulminans associated with disseminated intravascular coagulation: Treatment with protein C concentrate. Pediatrics 1993; 91: 418-422
-
(1993)
Pediatrics
, vol.91
, pp. 418-422
-
-
Gerson, W.T.1
Dickerman, J.D.2
Bovill, E.G.3
-
70
-
-
0028958909
-
Treatment of purpura fulminans in meningococcemia with protein C concentrate
-
70. Rivard GE, David M, Farrell C, et al: Treatment of purpura fulminans in meningococcemia with protein C concentrate. J Pediatr 1995; 126:646-652
-
(1995)
J Pediatr
, vol.126
, pp. 646-652
-
-
Rivard, G.E.1
David, M.2
Farrell, C.3
-
71
-
-
15844395458
-
Protein C in the treatment of coagulopathy in meningococcal disease
-
71. Rintala E, Seppala O, Kotilainen P, et al: Protein C in the treatment of coagulopathy in meningococcal disease. Lancet 1996; 347: 1767
-
(1996)
Lancet
, vol.347
, pp. 1767
-
-
Rintala, E.1
Seppala, O.2
Kotilainen, P.3
-
72
-
-
0031590612
-
Use of protein C concentrate, heparin, and haemodiafiltration in meningococcus-induced purpura fulminans
-
72. Smith OP, White B, Vaughan D, et al: Use of protein C concentrate, heparin, and haemodiafiltration in meningococcus-induced purpura fulminans. Lancet 1997; 350: 1590-1593
-
(1997)
Lancet
, vol.350
, pp. 1590-1593
-
-
Smith, O.P.1
White, B.2
Vaughan, D.3
-
73
-
-
0000586696
-
Treatment of DIC in septic shock with protein C concentrate
-
73. Veldman A, Escuriola-Ettingshausen C, Beeg T, et al: Treatment of DIC in septic shock with protein C concentrate. Blood 1997; 90: 3271
-
(1997)
Blood
, vol.90
, pp. 3271
-
-
Veldman, A.1
Escuriola-Ettingshausen, C.2
Beeg, T.3
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