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Volumn 28, Issue 11, 2003, Pages 1983-1990

The R7 Subfamily of RGS Proteins Assists Tachyphylaxis and Acute Tolerance at μ-Opioid Receptors

Author keywords

Antinociception; Antisense technology; G proteins; Mouse brain; Regulator of G protein signaling

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; BETA ENDORPHIN; DELTA OPIATE RECEPTOR AGONIST; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; GUANINE NUCLEOTIDE BINDING PROTEIN; MESSENGER RNA; MU OPIATE RECEPTOR; RGS PROTEIN; RGS11 PROTEIN; RGS6 PROTEIN; RGS7 PROTEIN; RGS9-2 PROTEIN; UNCLASSIFIED DRUG;

EID: 19244367478     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1300263     Document Type: Article
Times cited : (56)

References (46)
  • 1
    • 0025827095 scopus 로고
    • Selective blockage of δ opioid receptors prevents the development of morphine tolerance and dependence in mice
    • Abdelhamid EE, Sultana M, Portoghese PS, Takemori AE (1991). Selective blockage of δ opioid receptors prevents the development of morphine tolerance and dependence in mice. J Pharmacol Exp Ther 258: 299-303.
    • (1991) J Pharmacol Exp Ther , vol.258 , pp. 299-303
    • Abdelhamid, E.E.1    Sultana, M.2    Portoghese, P.S.3    Takemori, A.E.4
  • 2
    • 0032529161 scopus 로고    scopus 로고
    • Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways
    • Axelrod JD, Miller JR, Shulman JM, Moon RT, Rerrimon N (1998). Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways. Genes Dev 12: 2610-2622.
    • (1998) Genes Dev , vol.12 , pp. 2610-2622
    • Axelrod, J.D.1    Miller, J.R.2    Shulman, J.M.3    Moon, R.T.4    Rerrimon, N.5
  • 3
    • 0032495804 scopus 로고    scopus 로고
    • Distribution of heterotrimeric G-protein β and γ subunits in the rat brain
    • Betty M, Harnish SW, Rhodes KJ, Cockett MI (1998). Distribution of heterotrimeric G-protein β and γ subunits in the rat brain. Neuroscience 85: 475-486.
    • (1998) Neuroscience , vol.85 , pp. 475-486
    • Betty, M.1    Harnish, S.W.2    Rhodes, K.J.3    Cockett, M.I.4
  • 4
    • 0031950047 scopus 로고    scopus 로고
    • Influence of Gz and Gi2 transducer proteins in the affinity of opioid agonists to μ receptors
    • Garzón J, Castro M, Sánchez-Blázquez P (1998). Influence of Gz and Gi2 transducer proteins in the affinity of opioid agonists to μ receptors. Eur J Neurosci 10: 2557-2564.
    • (1998) Eur J Neurosci , vol.10 , pp. 2557-2564
    • Garzón, J.1    Castro, M.2    Sánchez-Blázquez, P.3
  • 5
    • 0032758137 scopus 로고    scopus 로고
    • In vivo modulation of G-proteins and opioid receptor function by antisense oligodeoxynucleotides
    • Garzón J, DeAntonio I, Sánchez-Blázquez P (2000). In vivo modulation of G-proteins and opioid receptor function by antisense oligodeoxynucleotides. Meth Enzymol 314: 3-20.
    • (2000) Meth Enzymol , vol.314 , pp. 3-20
    • Garzón, J.1    DeAntonio, I.2    Sánchez-Blázquez, P.3
  • 9
    • 0035089407 scopus 로고    scopus 로고
    • i2α subunits prevents acute tolerance (tachyphylaxis) to mu-opioid effects in mice
    • i2α subunits prevents acute tolerance (tachyphylaxis) to mu-opioid effects in mice. Neuropharmacology 40: 560-569.
    • (2001) Neuropharmacology , vol.40 , pp. 560-569
    • Garzón, J.1    Sánchez-Blázquez, P.2
  • 10
    • 0030764226 scopus 로고    scopus 로고
    • Regulators of G-protein signaling (RGS) proteins; region-specific expression of nine subtypes in rat brain
    • Gold SJ, Ni YG, Dohlmam HG, Nestler EJ (1997). Regulators of G-protein signaling (RGS) proteins; region-specific expression of nine subtypes in rat brain. J Neurosci 17: 8024-8037.
    • (1997) J Neurosci , vol.17 , pp. 8024-8037
    • Gold, S.J.1    Ni, Y.G.2    Dohlmam, H.G.3    Nestler, E.J.4
  • 11
    • 0031782937 scopus 로고    scopus 로고
    • Molecular characterization of human and rat RGS 9L, a novel splice variant enriched in dopamine target regions, and chromosomal localization of the RGS 9 gene
    • Granneman JG, Zhai Y, Zhu Z, Bannon MJ, Burchett SA, Schmidt CJ et al (1998). Molecular characterization of human and rat RGS 9L, a novel splice variant enriched in dopamine target regions, and chromosomal localization of the RGS 9 gene. Mol Pharmacol 54: 687-694.
    • (1998) Mol Pharmacol , vol.54 , pp. 687-694
    • Granneman, J.G.1    Zhai, Y.2    Zhu, Z.3    Bannon, M.J.4    Burchett, S.A.5    Schmidt, C.J.6
  • 12
    • 0033199157 scopus 로고    scopus 로고
    • Emerging roles for RGS proteins in cell signalling
    • Hepler JR (1999). Emerging roles for RGS proteins in cell signalling. Trends Pharmacol Sci 20: 376-382.
    • (1999) Trends Pharmacol Sci , vol.20 , pp. 376-382
    • Hepler, J.R.1
  • 13
    • 0036733358 scopus 로고    scopus 로고
    • Cellular regulation of RGS proteins: Modulators and integrators of G protein signaling
    • Hollinger S, Hepler JR (2002). Cellular regulation of RGS proteins: modulators and integrators of G protein signaling. Pharmacol Rev 54: 527-559.
    • (2002) Pharmacol Rev , vol.54 , pp. 527-559
    • Hollinger, S.1    Hepler, J.R.2
  • 14
    • 0018226370 scopus 로고
    • Single-dose tolerance to antinociception, and physical dependence on β-endorphin in mice
    • Huidobro-Toro JP, Way EL (1978). Single-dose tolerance to antinociception, and physical dependence on β-endorphin in mice. Eur J Pharmacol 52: 179-189.
    • (1978) Eur J Pharmacol , vol.52 , pp. 179-189
    • Huidobro-Toro, J.P.1    Way, E.L.2
  • 15
    • 0022558916 scopus 로고
    • III. Comparison of the antinociceptive action of mu and delta opioid receptor ligands in the periaqueductal grey matter, medial and paramedial ventral medulla in the rat as studied by the microinjection technique
    • Jensen TS, Yaksh TL (1986). III. Comparison of the antinociceptive action of mu and delta opioid receptor ligands in the periaqueductal grey matter, medial and paramedial ventral medulla in the rat as studied by the microinjection technique. Brain Res 372: 301-312.
    • (1986) Brain Res , vol.372 , pp. 301-312
    • Jensen, T.S.1    Yaksh, T.L.2
  • 16
    • 0030045115 scopus 로고    scopus 로고
    • An antisense oligodeoxynucleotide to the δ opioid receptor (DOR-1) inhibits morphine tolerance and acute dependence in mice
    • Kest B, Lee CE, Mclemore GL, Inturrisi CE (1996). An antisense oligodeoxynucleotide to the δ opioid receptor (DOR-1) inhibits morphine tolerance and acute dependence in mice. Brain Res Bull 39: 185-188.
    • (1996) Brain Res Bull , vol.39 , pp. 185-188
    • Kest, B.1    Lee, C.E.2    Mclemore, G.L.3    Inturrisi, C.E.4
  • 18
    • 0036462451 scopus 로고    scopus 로고
    • Oligomerization of opioid receptors: Generation of novel signaling units
    • Levac BA, O'Dowd BF, George SR (2002). Oligomerization of opioid receptors: generation of novel signaling units. Curr Opin Pharmacol 2: 76-81.
    • (2002) Curr Opin Pharmacol , vol.2 , pp. 76-81
    • Levac, B.A.1    O'Dowd, B.F.2    George, S.R.3
  • 19
    • 0019061918 scopus 로고
    • LIGAND: A versatile computerized approach for characterization of ligand-binding systems
    • Munson PJ, Rodbard D (1980). LIGAND: a versatile computerized approach for characterization of ligand-binding systems. Anal Biochem 107: 220-239.
    • (1980) Anal Biochem , vol.107 , pp. 220-239
    • Munson, P.J.1    Rodbard, D.2
  • 20
    • 0027425151 scopus 로고
    • Involvement of δ2 opioid receptors in the development of morphine dependence in mice
    • Miyamoto Y, Portoghese PS, Takemori AE (1993). Involvement of δ2 opioid receptors in the development of morphine dependence in mice. J Pharmacol Exp Ther 264: 1141-1145.
    • (1993) J Pharmacol Exp Ther , vol.264 , pp. 1141-1145
    • Miyamoto, Y.1    Portoghese, P.S.2    Takemori, A.E.3
  • 21
    • 0033562392 scopus 로고    scopus 로고
    • Region-specific regulation of RGS4 (regulator of G-protein-signaling protein type 4) in brain by stress and glucocorticoids: In vivo and in vitro studies
    • Ni YG, Gold SJ, Iredale PA, Terwilliger RZ, Duman RS, Nestler EJ (1999). Region-specific regulation of RGS4 (regulator of G-protein-signaling protein type 4) in brain by stress and glucocorticoids: in vivo and in vitro studies. J Neurosci 19: 3674-3680.
    • (1999) J Neurosci , vol.19 , pp. 3674-3680
    • Ni, Y.G.1    Gold, S.J.2    Iredale, P.A.3    Terwilliger, R.Z.4    Duman, R.S.5    Nestler, E.J.6
  • 22
    • 0037115025 scopus 로고    scopus 로고
    • Genetic dissociation of opiate tolerance and physical dependence in δ-opioid receptor-1 and preproenkephalin knock-out mice
    • Nitsche JF, Schuller AGP, King MA, Zengh M, Pasternak GW, Pintar JE (2002). Genetic dissociation of opiate tolerance and physical dependence in δ-opioid receptor-1 and preproenkephalin knock-out mice. J Neurosci 22: 10906-10913.
    • (2002) J Neurosci , vol.22 , pp. 10906-10913
    • Nitsche, J.F.1    Schuller, A.G.P.2    King, M.A.3    Zengh, M.4    Pasternak, G.W.5    Pintar, J.E.6
  • 23
    • 0032695796 scopus 로고    scopus 로고
    • Regulators of G protein signaling 6 and 7. Purification of complexes with Gβ5 and assessment of their effects on G protein-mediated signaling pathways
    • Posner BA, Gilman AG, Harris BA (1999). Regulators of G protein signaling 6 and 7. Purification of complexes with Gβ5 and assessment of their effects on G protein-mediated signaling pathways. J Biol Chem 274: 31087-31093.
    • (1999) J Biol Chem , vol.274 , pp. 31087-31093
    • Posner, B.A.1    Gilman, A.G.2    Harris, B.A.3
  • 24
    • 0033559843 scopus 로고    scopus 로고
    • Cloning and characterization of RGS9-2: A striatal-enriched alternatively spliced product of the RGS9 gene
    • Rahman Z, Gold SJ, Potenza MN, Cowan CW, Ni YG, He W et al (1999). Cloning and characterization of RGS9-2: a striatal-enriched alternatively spliced product of the RGS9 gene. J Neurosci 19: 2016-2026.
    • (1999) J Neurosci , vol.19 , pp. 2016-2026
    • Rahman, Z.1    Gold, S.J.2    Potenza, M.N.3    Cowan, C.W.4    Ni, Y.G.5    He, W.6
  • 26
    • 0033783132 scopus 로고    scopus 로고
    • GTPase-activating proteins for heterotrimeric G proteins: Regulators of G protein signaling (RGS) and RGS-like proteins
    • Ross EM, Wilkie TM (2000). GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins. Ann Rev Biochem 69: 795-827.
    • (2000) Ann Rev Biochem , vol.69 , pp. 795-827
    • Ross, E.M.1    Wilkie, T.M.2
  • 27
    • 0028047065 scopus 로고
    • μ and δ opioid synergy between the periaqueductal gray and the rostroventral medulla
    • Rossi GC, Pasternak GW, Bodnar RJ (1994). μ and δ opioid synergy between the periaqueductal gray and the rostroventral medulla. Brain Res 665: 85-93.
    • (1994) Brain Res , vol.665 , pp. 85-93
    • Rossi, G.C.1    Pasternak, G.W.2    Bodnar, R.J.3
  • 29
    • 0029552394 scopus 로고
    • In vivo injection of oligodeoxynucleotides to Ga subunits and supra-spinal analgesia evoked by mu and delta opioid agonists
    • Sánchez-Blázquez P, García-España A, Garzón J (1995). In vivo injection of oligodeoxynucleotides to Ga subunits and supra-spinal analgesia evoked by mu and delta opioid agonists. J Pharmacol Exp Ther 275: 1590-1596.
    • (1995) J Pharmacol Exp Ther , vol.275 , pp. 1590-1596
    • Sánchez-Blázquez, P.1    García-España, A.2    Garzón, J.3
  • 30
    • 0030947808 scopus 로고    scopus 로고
    • Antisense oligodeoxynucleotides to opioid Mu and Delta receptors reduced morphine dependence in mice: Role of Delta-2 opioid receptors
    • Sánchez-Blázquez P, García-España A, Garzón J (1997). Antisense oligodeoxynucleotides to opioid Mu and Delta receptors reduced morphine dependence in mice: role of Delta-2 opioid receptors. J Pharmacol Exp Ther 280: 1423-1431.
    • (1997) J Pharmacol Exp Ther , vol.280 , pp. 1423-1431
    • Sánchez-Blázquez, P.1    García-España, A.2    Garzón, J.3
  • 31
    • 0027234344 scopus 로고
    • Opioid supraspinal antinociception in mice is mediated by Gi3 transducer proteins
    • Sánchez-Blázquez P, Garzón J (1993). Opioid supraspinal antinociception in mice is mediated by Gi3 transducer proteins. Life Sci/Pharmacol Lett 53: PL129-PL134.
    • (1993) Life Sci/Pharmacol Lett , vol.53
    • Sánchez-Blázquez, P.1    Garzón, J.2
  • 32
    • 0031808936 scopus 로고    scopus 로고
    • Delta opioid receptor subtypes activate inositol-signaling pathways in the production of antinociception
    • Sánchez-Blázquez P, Garzón J (1998). Delta opioid receptor subtypes activate inositol-signaling pathways in the production of antinociception. J Pharmacol Exp Ther 285: 820-827.
    • (1998) J Pharmacol Exp Ther , vol.285 , pp. 820-827
    • Sánchez-Blázquez, P.1    Garzón, J.2
  • 35
    • 0034467579 scopus 로고    scopus 로고
    • Regulators of G-protein signaling in receptor complexes
    • Sierra DA, Popov S, Wilkie TM (2000). Regulators of G-protein signaling in receptor complexes. Trends Cardiovas Med 10: 263-228.
    • (2000) Trends Cardiovas Med , vol.10 , pp. 263-1228
    • Sierra, D.A.1    Popov, S.2    Wilkie, T.M.3
  • 36
    • 0032573221 scopus 로고    scopus 로고
    • A G protein γ subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gβ5 subunits
    • Snow BE, Krumins AM, Brothers GM, Lee S-F, Wall MA, Chung S et al (1998). A G protein γ subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gβ5 subunits. Proc Natl Acad Sci USA 95: 13307-13312.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13307-13312
    • Snow, B.E.1    Krumins, A.M.2    Brothers, G.M.3    Lee, S.-F.4    Wall, M.A.5    Chung, S.6
  • 37
    • 0035354341 scopus 로고    scopus 로고
    • Gγ-like (GGL) domains: New frontiers in G-protein signaling and beta-propeller scaffolding
    • Sondek J, Siderovski DP (2001). Gγ-like (GGL) domains: new frontiers in G-protein signaling and beta-propeller scaffolding. Biochem Pharmacol 61: 1329-1337.
    • (2001) Biochem Pharmacol , vol.61 , pp. 1329-1337
    • Sondek, J.1    Siderovski, D.P.2
  • 38
    • 0029837191 scopus 로고    scopus 로고
    • Differential blockade of opioid analgesia by antisense oligodeoxynucleotides directed against various G protein α subunits
    • Standifer KM, Rossi GC, Pasternak GW (1996). Differential blockade of opioid analgesia by antisense oligodeoxynucleotides directed against various G protein α subunits. Mol Pharmacol 50: 293-298.
    • (1996) Mol Pharmacol , vol.50 , pp. 293-298
    • Standifer, K.M.1    Rossi, G.C.2    Pasternak, G.W.3
  • 39
    • 0032053616 scopus 로고    scopus 로고
    • RGS9: A regulator of G-protein signalling with specific expression in rat and mouse striatum
    • Thomas EA, Danielson PE, Sutcliffe JG (1998). RGS9: a regulator of G-protein signalling with specific expression in rat and mouse striatum. J Neurosci Res 52: 118-124.
    • (1998) J Neurosci Res , vol.52 , pp. 118-124
    • Thomas, E.A.1    Danielson, P.E.2    Sutcliffe, J.G.3
  • 40
    • 0029985041 scopus 로고    scopus 로고
    • A novel form of the G protein β subunit Gβ5 is specifically expressed in the vertebrate retina
    • Watson AJ, Aragay AM, Slepak VZ, Simon MI (1996). A novel form of the G protein β subunit Gβ5 is specifically expressed in the vertebrate retina. J Biol Chem 271: 28154-28160.
    • (1996) J Biol Chem , vol.271 , pp. 28154-28160
    • Watson, A.J.1    Aragay, A.M.2    Slepak, V.Z.3    Simon, M.I.4
  • 41
    • 0028068380 scopus 로고
    • A fifth member of the mammalian G-protein β-subunit family
    • Watson AJ, Katz A, Simon MI (1994). A fifth member of the mammalian G-protein β-subunit family. J Biol Chem 269: 22150-22156.
    • (1994) J Biol Chem , vol.269 , pp. 22150-22156
    • Watson, A.J.1    Katz, A.2    Simon, M.I.3
  • 42
    • 0017089254 scopus 로고
    • Systematic examination in the rat of brain sites sensitive to the direct application of morphine: Observation of differential effects within the peria-queductal grey
    • Yaksh TL, Yeung JC, Rudy TA (1976). Systematic examination in the rat of brain sites sensitive to the direct application of morphine: observation of differential effects within the peria-queductal grey. Brain Res 114: 83-103.
    • (1976) Brain Res , vol.114 , pp. 83-103
    • Yaksh, T.L.1    Yeung, J.C.2    Rudy, T.A.3
  • 43
    • 0034125254 scopus 로고    scopus 로고
    • Differential expression of the G protein β5 gene: Analysis of mouse brain, peripheral tissues, and cultured cell lines
    • Zhang J-H, Lai Z, Simonds WF (2000). Differential expression of the G protein β5 gene: analysis of mouse brain, peripheral tissues, and cultured cell lines. J Neurochem 75: 393-403.
    • (2000) J Neurochem , vol.75 , pp. 393-403
    • Zhang, J.-H.1    Lai, Z.2    Simonds, W.F.3
  • 44
    • 0034138114 scopus 로고    scopus 로고
    • Copurification of brain G-protein β5 with RGS6 and RGS7
    • RC59
    • Zhang JH, Simonds WF (2000). Copurification of brain G-protein β5 with RGS6 and RGS7. J Neurosci 20, RC59 (1-5).
    • (2000) J Neurosci , vol.20 , Issue.1-5
    • Zhang, J.H.1    Simonds, W.F.2
  • 45
    • 0035976614 scopus 로고    scopus 로고
    • RGS-PX1, a GAP for Gαs and sorting nexin in vesicular trafficking
    • Zheng B, Ma YC, Ostrom RS, Lavoie C, Gill GN, Insel GN et al (2001). RGS-PX1, a GAP for Gαs and sorting nexin in vesicular trafficking. Science 30: 1939-1942.
    • (2001) Science , vol.30 , pp. 1939-1942
    • Zheng, B.1    Ma, Y.C.2    Ostrom, R.S.3    Lavoie, C.4    Gill, G.N.5    Insel, G.N.6
  • 46
    • 0033198831 scopus 로고    scopus 로고
    • Retention of supraspinal delta-like analgesia and loss of morphine tolerance in δ opioid receptor kockout mice
    • Zhu Y, King MA, Schuller AGP, Nitsche JF, Reidi M, Elde RP et al (1999). Retention of supraspinal delta-like analgesia and loss of morphine tolerance in δ opioid receptor kockout mice. Neuron 24: 243-252.
    • (1999) Neuron , vol.24 , pp. 243-252
    • Zhu, Y.1    King, M.A.2    Schuller, A.G.P.3    Nitsche, J.F.4    Reidi, M.5    Elde, R.P.6


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