Role of active site rigidity in activity: Md simulation and fluorescence study on a lipase mutant

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Kamal, Md Zahid ^a   Mohammad, Tabrez Anwar Shamim ^b,d   Krishnamoorthy, G ^c   Rao, Nalam Madhusudhana ^a  

^a CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

^b CENTRE FOR DNA FINGERPRINTING AND DIAGNOSTICS   (India)

^c TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

^d UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUTANT PROTEIN; TRIACYLGLYCEROL LIPASE;

ANISOTROPY; ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVE SITE RIGIDITY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME CONFORMATION; ENZYME ENGINEERING; ENZYME KINETICS; ENZYME PURIFICATION; ENZYME STABILITY; ENZYME STRUCTURE; FLUORESCENCE ANALYSIS; MOLECULAR DYNAMICS; PROTEIN EXPRESSION; WILD TYPE; BACILLUS SUBTILIS; CHEMISTRY; ENZYMOLOGY; FLUORESCENCE; GENETICS; HYDROLYSIS; METABOLISM; PROTEIN SECONDARY STRUCTURE;

BACILLUS SUBTILIS; CATALYSIS; CATALYTIC DOMAIN; FLUORESCENCE; HYDROLYSIS; LIPASE; MOLECULAR DYNAMICS SIMULATION; PROTEIN STRUCTURE, SECONDARY;

EID: 84859722834     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035188     Document Type: Article

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