Microglial neurotransmitter receptors trigger superoxide production in microglia; consequences for microglial-neuronal interactions

Journal of Neurochemistry

Volumn 121, Issue 2, 2012, Pages 287-301

  Mead, Emma L ^a   Mosley, Angelina ^a   Eaton, Simon ^b   Dobson, Lucianne ^a   Heales, Simon J ^b   Pocock, Jennifer M ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Microglia; Neurotransmitters; Receptors; Superoxide

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR; ADENOSINE TRIPHOSPHATE; GLUTAMIC ACID; METABOTROPIC RECEPTOR 3; METABOTROPIC RECEPTOR AGONIST; METABOTROPIC RECEPTOR ANTAGONIST; NEUROTRANSMITTER RECEPTOR; PURINERGIC P2X7 RECEPTOR; PURINERGIC P2Y2 RECEPTOR; PURINERGIC P2Y4 RECEPTOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SUPEROXIDE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL ACTIVITY; CELL INTERACTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME REGULATION; ENZYME SYNTHESIS; MICROGLIA; MOUSE; NERVE DEGENERATION; NERVE STIMULATION; NEUROMODULATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; CEREBELLUM; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLOW CYTOMETRY; FLUORESCENT DYES; GABA AGONISTS; HYDROGEN PEROXIDE; ISOENZYMES; MICE; MICROGLIA; NADPH OXIDASE; NEURONS; NITROBLUE TETRAZOLIUM; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, GABA; RECEPTORS, GLUTAMATE; RECEPTORS, NEUROTRANSMITTER; RECEPTORS, PURINERGIC P2; RNA; SUPEROXIDES;

RATTUS; RODENTIA;

EID: 84859648049     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2012.07659.x     Document Type: Article

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