-
1
-
-
0036083396
-
The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction
-
Glickman MH, Ciechanover A, (2002) The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev 82: 373-428.
-
(2002)
Physiol Rev
, vol.82
, pp. 373-428
-
-
Glickman, M.H.1
Ciechanover, A.2
-
2
-
-
77950517895
-
Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A
-
Pereg Y, Liu BY, O'Rourke KM, Sagolla M, Dey A, et al. (2010) Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A. Nat Cell Biol 12: 400-406.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 400-406
-
-
Pereg, Y.1
Liu, B.Y.2
O'Rourke, K.M.3
Sagolla, M.4
Dey, A.5
-
3
-
-
54249104026
-
The ubiquitin system, disease, and drug discovery
-
Petroski M, (2008) The ubiquitin system, disease, and drug discovery. BMC Biochemistry 9: S7.
-
(2008)
BMC Biochemistry
, vol.9
-
-
Petroski, M.1
-
4
-
-
79959539790
-
Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death
-
Vucic D, Dixit VM, Wertz IE, (2011) Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death. Nat Rev Mol Cell Biol 12: 439-452.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, pp. 439-452
-
-
Vucic, D.1
Dixit, V.M.2
Wertz, I.E.3
-
5
-
-
0035339232
-
The schedule of destruction of three mitotic cyclins can dictate the timing of events during exit from mitosis
-
Parry DH, O'Farrell PH, (2001) The schedule of destruction of three mitotic cyclins can dictate the timing of events during exit from mitosis. Curr Biol 11: 671-683.
-
(2001)
Curr Biol
, vol.11
, pp. 671-683
-
-
Parry, D.H.1
O'Farrell, P.H.2
-
6
-
-
0032512748
-
Budding yeast Cdc20: a target of the spindle checkpoint
-
Hwang LH, Lau LF, Smith DL, Mistrot CA, Hardwick KG, et al. (1998) Budding yeast Cdc20: a target of the spindle checkpoint. Science 279: 1041-1044.
-
(1998)
Science
, vol.279
, pp. 1041-1044
-
-
Hwang, L.H.1
Lau, L.F.2
Smith, D.L.3
Mistrot, C.A.4
Hardwick, K.G.5
-
7
-
-
0033592543
-
Deletion of the Cul1 gene in mice causes arrest in early embryogenesis and accumulation of cyclin E
-
Wang Y, Penfold S, Tang X, Hattori N, Riley P, et al. (1999) Deletion of the Cul1 gene in mice causes arrest in early embryogenesis and accumulation of cyclin E. Current Biology 9: 1191-1194.
-
(1999)
Current Biology
, vol.9
, pp. 1191-1194
-
-
Wang, Y.1
Penfold, S.2
Tang, X.3
Hattori, N.4
Riley, P.5
-
8
-
-
0034595292
-
Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication
-
Nakayama K, Nagahama H, Minamishima YA, Matsumoto M, Nakamichi I, et al. (2000) Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication. Embo Journal 19: 2069-2081.
-
(2000)
Embo Journal
, vol.19
, pp. 2069-2081
-
-
Nakayama, K.1
Nagahama, H.2
Minamishima, Y.A.3
Matsumoto, M.4
Nakamichi, I.5
-
9
-
-
34248525919
-
The after-hours mutant reveals a role for Fbxl3 in determining mammalian circadian period
-
Godinho SI, Maywood ES, Shaw L, Tucci V, Barnard AR, et al. (2007) The after-hours mutant reveals a role for Fbxl3 in determining mammalian circadian period. Science 316: 897-900.
-
(2007)
Science
, vol.316
, pp. 897-900
-
-
Godinho, S.I.1
Maywood, E.S.2
Shaw, L.3
Tucci, V.4
Barnard, A.R.5
-
10
-
-
34248566788
-
SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins
-
Busino L, Bassermann F, Maiolica A, Lee C, Nolan PM, et al. (2007) SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins. Science 316: 900-904.
-
(2007)
Science
, vol.316
, pp. 900-904
-
-
Busino, L.1
Bassermann, F.2
Maiolica, A.3
Lee, C.4
Nolan, P.M.5
-
11
-
-
0025826876
-
Modeling the cell division cycle: cdc2 and cyclin interactions
-
Tyson JJ, (1991) Modeling the cell division cycle: cdc2 and cyclin interactions. Proc Natl Acad Sci U S A 88: 7328-7332.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 7328-7332
-
-
Tyson, J.J.1
-
12
-
-
0344982141
-
Dynamics of the cell cycle-checkpoints, sizers and timers
-
Qu Z, MacLellan WR, Weiss JN, (2003) Dynamics of the cell cycle-checkpoints, sizers and timers. Biophys J 85: 3600-3611.
-
(2003)
Biophys J
, vol.85
, pp. 3600-3611
-
-
Qu, Z.1
MacLellan, W.R.2
Weiss, J.N.3
-
13
-
-
0037302108
-
Regulation of the mammalian cell cycle: a model of the G1-to-S transition
-
Qu Z, Weiss JN, MacLellan WR, (2003) Regulation of the mammalian cell cycle: a model of the G1-to-S transition. Am J Physiol Cell Physiol 284: C349-364.
-
(2003)
Am J Physiol Cell Physiol
, vol.284
-
-
Qu, Z.1
Weiss, J.N.2
MacLellan, W.R.3
-
14
-
-
73349138265
-
Dependence of the period on the rate of protein degradation in minimal models for circadian oscillations
-
Gerard C, Gonze D, Goldbeter A, (2009) Dependence of the period on the rate of protein degradation in minimal models for circadian oscillations. Philos Transact A Math Phys Eng Sci 367: 4665-4683.
-
(2009)
Philos Transact A Math Phys Eng Sci
, vol.367
, pp. 4665-4683
-
-
Gerard, C.1
Gonze, D.2
Goldbeter, A.3
-
15
-
-
79957710315
-
Quantifying the Waddington landscape and biological paths for development and differentiation
-
Wang J, Zhang K, Xu L, Wang E, (2011) Quantifying the Waddington landscape and biological paths for development and differentiation. Proc Natl Acad Sci U S A 108: 8257-8262.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 8257-8262
-
-
Wang, J.1
Zhang, K.2
Xu, L.3
Wang, E.4
-
16
-
-
77957564565
-
Ubiquitylation of the amino terminus of Myc by SCF(beta-TrCP) antagonizes SCF(Fbw7)-mediated turnover
-
Popov N, Schulein C, Jaenicke LA, Eilers M, (2010) Ubiquitylation of the amino terminus of Myc by SCF(beta-TrCP) antagonizes SCF(Fbw7)-mediated turnover. Nat Cell Biol 12: 973-981.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 973-981
-
-
Popov, N.1
Schulein, C.2
Jaenicke, L.A.3
Eilers, M.4
-
17
-
-
4344658879
-
SspB delivery of substrates for ClpXP proteolysis probed by the design of improved degradation tags
-
Hersch GL, Baker TA, Sauer RT, (2004) SspB delivery of substrates for ClpXP proteolysis probed by the design of improved degradation tags. Proc Natl Acad Sci U S A 101: 12136-12141.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 12136-12141
-
-
Hersch, G.L.1
Baker, T.A.2
Sauer, R.T.3
-
18
-
-
34547572517
-
Single-cell zeroth-order protein degradation enhances the robustness of synthetic oscillator
-
Wong WW, Tsai TY, Liao JC, (2007) Single-cell zeroth-order protein degradation enhances the robustness of synthetic oscillator. Mol Syst Biol 3: 130.
-
(2007)
Mol Syst Biol
, vol.3
, pp. 130
-
-
Wong, W.W.1
Tsai, T.Y.2
Liao, J.C.3
-
19
-
-
0026006671
-
A minimal cascade model for the mitotic oscillator involving cyclin and cdc2 kinase
-
Goldbeter A, (1991) A minimal cascade model for the mitotic oscillator involving cyclin and cdc2 kinase. Proc Natl Acad Sci U S A 88: 9107-9111.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 9107-9111
-
-
Goldbeter, A.1
-
20
-
-
33746605149
-
Minimal model of spiky oscillations in NF-kappaB signaling
-
Krishna S, Jensen MH, Sneppen K, (2006) Minimal model of spiky oscillations in NF-kappaB signaling. Proc Natl Acad Sci U S A 103: 10840-10845.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 10840-10845
-
-
Krishna, S.1
Jensen, M.H.2
Sneppen, K.3
-
21
-
-
0037795575
-
Toward a detailed computational model for the mammalian circadian clock
-
Leloup JC, Goldbeter A, (2003) Toward a detailed computational model for the mammalian circadian clock. Proc Natl Acad Sci U S A 100: 7051-7056.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 7051-7056
-
-
Leloup, J.C.1
Goldbeter, A.2
-
22
-
-
0021715523
-
Ultrasensitivity in biochemical systems controlled by covalent modification
-
Goldbeter A, Koshland DE, (1984) Ultrasensitivity in biochemical systems controlled by covalent modification. J Biol Chem 259: 14441-14447.
-
(1984)
J Biol Chem
, vol.259
, pp. 14441-14447
-
-
Goldbeter, A.1
Koshland, D.E.2
-
23
-
-
71449123070
-
Detection of sequential polyubiquitylation on a millisecond timescale
-
Pierce NW, Kleiger G, Shan SO, Deshaies RJ, (2009) Detection of sequential polyubiquitylation on a millisecond timescale. Nature 462: 615-619.
-
(2009)
Nature
, vol.462
, pp. 615-619
-
-
Pierce, N.W.1
Kleiger, G.2
Shan, S.O.3
Deshaies, R.J.4
-
24
-
-
2242458129
-
Biochemical oscillations
-
In: Fall CP, Marland ES, Wagner JM, Tyson JJ, editors, New York, Berlin, Springer
-
Tyson JJ, (2002) Biochemical oscillations. In: Fall CP, Marland ES, Wagner JM, Tyson JJ, editors. Computational Cell Biology New York, Berlin Springer pp. 230-260.
-
(2002)
Computational Cell Biology
, pp. 230-260
-
-
Tyson, J.J.1
-
25
-
-
46849090495
-
Robust, tunable biological oscillations from interlinked positive and negative feedback loops
-
Tsai TY, Choi YS, Ma W, Pomerening JR, Tang C, et al. (2008) Robust, tunable biological oscillations from interlinked positive and negative feedback loops. Science 321: 126-129.
-
(2008)
Science
, vol.321
, pp. 126-129
-
-
Tsai, T.Y.1
Choi, Y.S.2
Ma, W.3
Pomerening, J.R.4
Tang, C.5
-
26
-
-
0037636269
-
A model of phosphofructokinase and glycolytic oscillations in the pancreatic beta-cell
-
Westermark PO, Lansner A, (2003) A model of phosphofructokinase and glycolytic oscillations in the pancreatic beta-cell. Biophys J 85: 126-139.
-
(2003)
Biophys J
, vol.85
, pp. 126-139
-
-
Westermark, P.O.1
Lansner, A.2
-
27
-
-
0345359924
-
A positive-feedback-based bistable 'memory module' that governs a cell fate decision
-
Xiong W, Ferrell JE Jr, (2003) A positive-feedback-based bistable 'memory module' that governs a cell fate decision. Nature 426: 460-465.
-
(2003)
Nature
, vol.426
, pp. 460-465
-
-
Xiong, W.1
Ferrell Jr., J.E.2
-
28
-
-
0028931265
-
Principles of CDK regulation
-
Morgan DO, (1995) Principles of CDK regulation. Nature 374: 131-134.
-
(1995)
Nature
, vol.374
, pp. 131-134
-
-
Morgan, D.O.1
-
29
-
-
0034688174
-
Construction of a genetic toggle switch in Escherichia coli
-
Gardner TS, Cantor CR, Collins JJ, (2000) Construction of a genetic toggle switch in Escherichia coli. Nature 403: 339-342.
-
(2000)
Nature
, vol.403
, pp. 339-342
-
-
Gardner, T.S.1
Cantor, C.R.2
Collins, J.J.3
-
30
-
-
84965044576
-
Nonlinear dynamics and Chaos: with applications to physics, biology, chemistry, and engineering
-
Cambridge, Westview Press
-
Strogatz SH, (2000) Nonlinear dynamics and Chaos: with applications to physics, biology, chemistry, and engineering. xi Cambridge Westview Press: 498.
-
(2000)
, vol.xi
, pp. 498
-
-
Strogatz, S.H.1
-
31
-
-
0034019315
-
Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades
-
Kholodenko BN, (2000) Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades. European Journal of Biochemistry 267: 1583-1588.
-
(2000)
European Journal of Biochemistry
, vol.267
, pp. 1583-1588
-
-
Kholodenko, B.N.1
-
32
-
-
2942683567
-
Multi-site Phosphorylation and Network Dynamics of Cyclin-Dependent Kinase Signaling in the Eukaryotic Cell Cycle
-
Yang L, MacLellan WR, Han Z, Weiss JN, Qu Z, (2004) Multi-site Phosphorylation and Network Dynamics of Cyclin-Dependent Kinase Signaling in the Eukaryotic Cell Cycle. Biophys J 86: 3432-3443.
-
(2004)
Biophys J
, vol.86
, pp. 3432-3443
-
-
Yang, L.1
MacLellan, W.R.2
Han, Z.3
Weiss, J.N.4
Qu, Z.5
-
33
-
-
64149132189
-
The effects of cascade length, kinetics and feedback loops on biological signal transduction dynamics in a simplified cascade model
-
Qu Z, Vondriska TM, (2009) The effects of cascade length, kinetics and feedback loops on biological signal transduction dynamics in a simplified cascade model. Phys Biol 6: 016007.
-
(2009)
Phys Biol
, vol.6
, pp. 016007
-
-
Qu, Z.1
Vondriska, T.M.2
-
34
-
-
70450228872
-
The combination of positive and negative feedback loops confers exquisite flexibility to biochemical switches
-
Pfeuty B, Kaneko K, (2009) The combination of positive and negative feedback loops confers exquisite flexibility to biochemical switches. Phys Biol 6: 046013.
-
(2009)
Phys Biol
, vol.6
, pp. 046013
-
-
Pfeuty, B.1
Kaneko, K.2
-
35
-
-
35649001607
-
A Quantitative Description of Membrane Current and Its Application to Conduction and Excitation in Nerve
-
Hodgkin AL, Huxley AF, (1952) A Quantitative Description of Membrane Current and Its Application to Conduction and Excitation in Nerve. Journal of Physiology-London 117: 500-544.
-
(1952)
Journal of Physiology-London
, vol.117
, pp. 500-544
-
-
Hodgkin, A.L.1
Huxley, A.F.2
-
36
-
-
0037376655
-
Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell
-
Tyson JJ, Chen KC, Novak B, (2003) Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell. Curr Opin Cell Biol 15: 221-231.
-
(2003)
Curr Opin Cell Biol
, vol.15
, pp. 221-231
-
-
Tyson, J.J.1
Chen, K.C.2
Novak, B.3
-
37
-
-
0037417803
-
Hysteresis drives cell-cycle transitions in Xenopus laevis egg extracts
-
Sha W, Moore J, Chen K, Lassaletta AD, Yi CS, et al. (2003) Hysteresis drives cell-cycle transitions in Xenopus laevis egg extracts. Proc Natl Acad Sci U S A 100: 975-980.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 975-980
-
-
Sha, W.1
Moore, J.2
Chen, K.3
Lassaletta, A.D.4
Yi, C.S.5
-
38
-
-
0345700833
-
Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2
-
Pomerening JR, Sontag ED, Ferrell JE Jr, (2003) Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2. Nat Cell Biol 5: 346-351.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 346-351
-
-
Pomerening, J.R.1
Sontag, E.D.2
Ferrell Jr., J.E.3
-
39
-
-
0013823048
-
Oscillatory behavior in enzymatic control processes
-
Goodwin BC, (1965) Oscillatory behavior in enzymatic control processes. Adv Enzyme Regul 3: 425-438.
-
(1965)
Adv Enzyme Regul
, vol.3
, pp. 425-438
-
-
Goodwin, B.C.1
-
40
-
-
0014319313
-
Mathematics of cellular control processes. I. Negative feedback to one gene
-
Griffith JS, (1968) Mathematics of cellular control processes. I. Negative feedback to one gene. J Theor Biol 20: 202-208.
-
(1968)
J Theor Biol
, vol.20
, pp. 202-208
-
-
Griffith, J.S.1
-
41
-
-
0019974626
-
Role of feedback inhibition in stabilizing the classical operon
-
Bliss RD, Painter PR, Marr AG, (1982) Role of feedback inhibition in stabilizing the classical operon. J Theor Biol 97: 177-193.
-
(1982)
J Theor Biol
, vol.97
, pp. 177-193
-
-
Bliss, R.D.1
Painter, P.R.2
Marr, A.G.3
-
42
-
-
22144443131
-
Nonlinear protein degradation and the function of genetic circuits
-
Buchler NE, Gerland U, Hwa T, (2005) Nonlinear protein degradation and the function of genetic circuits. Proc Natl Acad Sci U S A 102: 9559-9564.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 9559-9564
-
-
Buchler, N.E.1
Gerland, U.2
Hwa, T.3
-
43
-
-
0037047611
-
MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network
-
Bhalla US, Ram PT, Iyengar R, (2002) MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network. Science 297: 1018-1023.
-
(2002)
Science
, vol.297
, pp. 1018-1023
-
-
Bhalla, U.S.1
Ram, P.T.2
Iyengar, R.3
-
44
-
-
0345600247
-
A protein interaction map of Drosophila melanogaster
-
Giot L, Bader JS, Brouwer C, Chaudhuri A, Kuang B, et al. (2003) A protein interaction map of Drosophila melanogaster. Science 302: 1727-1736.
-
(2003)
Science
, vol.302
, pp. 1727-1736
-
-
Giot, L.1
Bader, J.S.2
Brouwer, C.3
Chaudhuri, A.4
Kuang, B.5
-
45
-
-
80053608521
-
Multi-scale modeling in biology: How to bridge the gaps between scales?
-
Qu Z, Garfinkel A, Weiss JN, Nivala M, (2011) Multi-scale modeling in biology: How to bridge the gaps between scales? Prog Biophys Mol Biol 107: 21-31.
-
(2011)
Prog Biophys Mol Biol
, vol.107
, pp. 21-31
-
-
Qu, Z.1
Garfinkel, A.2
Weiss, J.N.3
Nivala, M.4
-
47
-
-
77955505159
-
The 20S proteasome splicing activity discovered by SpliceMet
-
Liepe J, Mishto M, Textoris-Taube K, Janek K, Keller C, et al. (2010) The 20S proteasome splicing activity discovered by SpliceMet. PLoS Comput Biol 6: e1000830.
-
(2010)
PLoS Comput Biol
, vol.6
-
-
Liepe, J.1
Mishto, M.2
Textoris-Taube, K.3
Janek, K.4
Keller, C.5
-
48
-
-
65449182391
-
Toward quantitative prediction of proteasomal digestion pattern of proteins
-
Goldobin DS, Zaikin A, (2009) Toward quantitative prediction of proteasomal digestion pattern of proteins. J Stat Mech 2009: P01009.
-
(2009)
J Stat Mech
, vol.2009
-
-
Goldobin, D.S.1
Zaikin, A.2
|