-
1
-
-
18644382993
-
Digenic inheritance of severe insulin resistance in a human pedigree
-
Savage DB, Agostini M, Barroso I, Gurnell M, Luan J, Meirhaeghe A, Harding AH, Ihrke G, Rajanayagam O, Soos MA, George S, Berger D, Thomas EL, Bell JD, Meeran K, Ross RJ, Vidal-Puig A, Wareham NJ, O'Rahilly S, Chatterjee VK, Schafer AJ: Digenic inheritance of severe insulin resistance in a human pedigree. Nat Genet 2002;31:379-384.
-
(2002)
Nat Genet
, vol.31
, pp. 379-384
-
-
Savage, D.B.1
Agostini, M.2
Barroso, I.3
Gurnell, M.4
Luan, J.5
Meirhaeghe, A.6
Harding, A.H.7
Ihrke, G.8
Rajanayagam, O.9
Soos, M.A.10
George, S.11
Berger, D.12
Thomas, E.L.13
Bell, J.D.14
Meeran, K.15
Ross, R.J.16
Vidal-Puig, A.17
Wareham, N.J.18
O'Rahilly, S.19
Chatterjee, V.K.20
Schafer, A.J.21
more..
-
2
-
-
0027230143
-
Insulin-mediated pseudoacromegaly: Clinical and biochemical characterization of a syndrome of selective insulin resistance
-
Flier JS, Moller DE, Moses AC, O'Rahilly S, Chaiken RL, Grigorescu F, Elahi D, Kahn BB, Weinreb JE, Eastman R: Insulin-mediated pseudoacromegaly: clinical and biochemical characterization of a syndrome of selective insulin resistance. J Clin Endocrinol Metab 1993;76:1533-1541.
-
(1993)
J Clin Endocrinol Metab
, vol.76
, pp. 1533-1541
-
-
Flier, J.S.1
Moller, D.E.2
Moses, A.C.3
O'Rahilly, S.4
Chaiken, R.L.5
Grigorescu, F.6
Elahi, D.7
Kahn, B.B.8
Weinreb, J.E.9
Eastman, R.10
-
3
-
-
1542510700
-
Acquired and inherited lipodystrophies
-
Garg A: Acquired and inherited lipodystrophies. N Engl J Med 2004;350:1220-1234.
-
(2004)
N Engl J Med
, vol.350
, pp. 1220-1234
-
-
Garg, A.1
-
4
-
-
33747735518
-
Elevated plasma adiponectin in humans with genetically defective insulin receptors
-
Semple RK, Soos MA, Luan J, Mitchell CS, Wilson JC, Gurnell M, Cochran EK, Gorden P, Chatterjee VK, Wareham NJ, O'Rahilly S: Elevated plasma adiponectin in humans with genetically defective insulin receptors. J Clin Endocrinol Metab 2006;91:3219-3223.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 3219-3223
-
-
Semple, R.K.1
Soos, M.A.2
Luan, J.3
Mitchell, C.S.4
Wilson, J.C.5
Gurnell, M.6
Cochran, E.K.7
Gorden, P.8
Chatterjee, V.K.9
Wareham, N.J.10
O'Rahilly, S.11
-
5
-
-
3242714887
-
Clinical course of genetic diseases of the insulin receptor (type A and Rabson-Mendenhall syndromes): A 30-year prospective
-
Musso C, Cochran E, Moran SA, Skarulis MC, Oral EA, Taylor S, Gorden P: Clinical course of genetic diseases of the insulin receptor (type A and Rabson-Mendenhall syndromes): a 30-year prospective. Medicine (Baltimore) 2004;83:209-222.
-
(2004)
Medicine (Baltimore)
, vol.83
, pp. 209-222
-
-
Musso, C.1
Cochran, E.2
Moran, S.A.3
Skarulis, M.C.4
Oral, E.A.5
Taylor, S.6
Gorden, P.7
-
6
-
-
0141790120
-
Methods for clinical assessment of insulin sensitivity and beta-cell function
-
Pacini G, Mari A: Methods for clinical assessment of insulin sensitivity and beta-cell function. Best Pract Res Clin Endocrinol Metab 2003;17:305-322.
-
(2003)
Best Pract Res Clin Endocrinol Metab
, vol.17
, pp. 305-322
-
-
Pacini, G.1
Mari, A.2
-
7
-
-
20444387992
-
Successful treatment of type B insulin resistance in a patient with otherwise quiescent systemic lupus erythematosus
-
Coll AP, Morganstein D, Jayne D, Soos MA, O'Rahilly S, Burke J: Successful treatment of type B insulin resistance in a patient with otherwise quiescent systemic lupus erythematosus. Diabet Med 2005;22:814-815.
-
(2005)
Diabet Med
, vol.22
, pp. 814-815
-
-
Coll, A.P.1
Morganstein, D.2
Jayne, D.3
Soos, M.A.4
O'Rahilly, S.5
Burke, J.6
-
8
-
-
0037148928
-
Leptin-replacement therapy for lipodystrophy
-
Oral EA, Simha V, Ruiz E, Andewelt A, Premkumar A, Snell P, Wagner AJ, DePaoli AM, Reitman ML, Taylor SI, Gorden P, Garg A: Leptin-replacement therapy for lipodystrophy. N Engl J Med 2002;346:570-578.
-
(2002)
N Engl J Med
, vol.346
, pp. 570-578
-
-
Oral, E.A.1
Simha, V.2
Ruiz, E.3
Andewelt, A.4
Premkumar, A.5
Snell, P.6
Wagner, A.J.7
DePaoli, A.M.8
Reitman, M.L.9
Taylor, S.I.10
Gorden, P.11
Garg, A.12
-
9
-
-
21344447493
-
Long-term efficacy of leptin replacement in patients with generalized lipodystrophy
-
Javor ED, Cochran EK, Musso C, Young JR, Depaoli AM, Gorden P: Long-term efficacy of leptin replacement in patients with generalized lipodystrophy. Diabetes 2005;54:1994-2002.
-
(2005)
Diabetes
, vol.54
, pp. 1994-2002
-
-
Javor, E.D.1
Cochran, E.K.2
Musso, C.3
Young, J.R.4
Depaoli, A.M.5
Gorden, P.6
-
10
-
-
0036800760
-
Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
-
Farooqi IS, Matarese G, Lord GM, Keogh JM, Lawrence E, Agwu C, Sanna V, Jebb SA, Perna F, Fontana S, Lechler RI, DePaoli AM, O'Rahilly S: Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency. J Clin Invest 2002;110:1093-1103.
-
(2002)
J Clin Invest
, vol.110
, pp. 1093-1103
-
-
Farooqi, I.S.1
Matarese, G.2
Lord, G.M.3
Keogh, J.M.4
Lawrence, E.5
Agwu, C.6
Sanna, V.7
Jebb, S.A.8
Perna, F.9
Fontana, S.10
Lechler, R.I.11
DePaoli, A.M.12
O'Rahilly, S.13
-
11
-
-
0036100839
-
Leptin: A novel therapeutic role in lipodystrophy
-
Savage DB, O'Rahilly S: Leptin: a novel therapeutic role in lipodystrophy. J Clin Invest 2002;109:1285-1286.
-
(2002)
J Clin Invest
, vol.109
, pp. 1285-1286
-
-
Savage, D.B.1
O'Rahilly, S.2
-
12
-
-
0038549106
-
Differential effects of rosiglitazone on skeletal muscle and liver insulin resistance in A-ZIP/F-1 fatless mice
-
Kim JK, Fillmore JJ, Gavrilova O, Chao L, Higashimori T, Choi H, Kim HJ, Yu C, Chen Y, Qu X, Haluzik M, Reitman ML, Shulman GI: Differential effects of rosiglitazone on skeletal muscle and liver insulin resistance in A-ZIP/F-1 fatless mice. Diabetes 2003;52:1311-1318.
-
(2003)
Diabetes
, vol.52
, pp. 1311-1318
-
-
Kim, J.K.1
Fillmore, J.J.2
Gavrilova, O.3
Chao, L.4
Higashimori, T.5
Choi, H.6
Kim, H.J.7
Yu, C.8
Chen, Y.9
Qu, X.10
Haluzik, M.11
Reitman, M.L.12
Shulman, G.I.13
-
13
-
-
0034663140
-
Efficacy and safety of troglitazone in the treatment of lipodystrophy syndromes
-
Arioglu E, Duncan-Morin J, Sebring N, Rother KI, Gottlieb N, Lieberman J, Herion D, Kleiner DE, Reynolds J, Premkumar A, Sumner AE, Hoofnagle J, Reitman ML, Taylor SI: Efficacy and safety of troglitazone in the treatment of lipodystrophy syndromes. Ann Intern Med 2000;133: 263-274.
-
(2000)
Ann Intern Med
, vol.133
, pp. 263-274
-
-
Arioglu, E.1
Duncan-Morin, J.2
Sebring, N.3
Rother, K.I.4
Gottlieb, N.5
Lieberman, J.6
Herion, D.7
Kleiner, D.E.8
Reynolds, J.9
Premkumar, A.10
Sumner, A.E.11
Hoofnagle, J.12
Reitman, M.L.13
Taylor, S.I.14
-
14
-
-
0344375097
-
Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma
-
Savage DB, Tan GD, Acerini CL, Jebb SA, Agostini M, Gurnell M, Williams RL, Umpleby AM, Thomas EL, Bell JD, Dixon AK, Dunne F, Boiani R, Cinti S, Vidal-Puig A, Karpe F, Chatterjee VK, O'Rahilly S: Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma. Diabetes 2003;52:910-917.
-
(2003)
Diabetes
, vol.52
, pp. 910-917
-
-
Savage, D.B.1
Tan, G.D.2
Acerini, C.L.3
Jebb, S.A.4
Agostini, M.5
Gurnell, M.6
Williams, R.L.7
Umpleby, A.M.8
Thomas, E.L.9
Bell, J.D.10
Dixon, A.K.11
Dunne, F.12
Boiani, R.13
Cinti, S.14
Vidal-Puig, A.15
Karpe, F.16
Chatterjee, V.K.17
O'Rahilly, S.18
-
15
-
-
18144428664
-
The use of U-500 in patients with extreme insulin resistance
-
Cochran E, Musso C, Gorden P: The use of U-500 in patients with extreme insulin resistance. Diabetes Care 2005;28:1240-1244.
-
(2005)
Diabetes Care
, vol.28
, pp. 1240-1244
-
-
Cochran, E.1
Musso, C.2
Gorden, P.3
-
16
-
-
0028118369
-
Adverse effects of recombinant human insulin-like growth factor I in obese insulin-resistant type II diabetic patients
-
Jabri N, Schalch DS, Schwartz SL, Fischer JS, Kipnes MS, Radnik BJ, Turman NJ, Marcsisin VS, Guler HP: Adverse effects of recombinant human insulin-like growth factor I in obese insulin-resistant type II diabetic patients. Diabetes 1994;43:369-374.
-
(1994)
Diabetes
, vol.43
, pp. 369-374
-
-
Jabri, N.1
Schalch, D.S.2
Schwartz, S.L.3
Fischer, J.S.4
Kipnes, M.S.5
Radnik, B.J.6
Turman, N.J.7
Marcsisin, V.S.8
Guler, H.P.9
-
17
-
-
17044409041
-
insulin-like growth factor-I/insulin-like growth factor binding protein-3, mecaserimin rinfibate, rhIGF-I/rhIGFBP-3
-
Mecasermin rinfabate: insulin-like growth factor-I/insulin-like growth factor binding protein-3, mecaserimin rinfibate, rhIGF-I/rhIGFBP-3. Drugs R D 2005;6:120-127.
-
(2005)
Drugs R D
, vol.6
, pp. 120-127
-
-
Mecasermin rinfabate1
-
18
-
-
1942441000
-
Efficacy of recombinant methionyl human leptin therapy for the extreme insulin resistance of the Rabson-Mendenhall syndrome
-
Cochran E, Young JR, Sebring N, DePaoli A, Oral EA, Gorden P: Efficacy of recombinant methionyl human leptin therapy for the extreme insulin resistance of the Rabson-Mendenhall syndrome. J Clin Endocrinol Metab 2004;89:1548-1554.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 1548-1554
-
-
Cochran, E.1
Young, J.R.2
Sebring, N.3
DePaoli, A.4
Oral, E.A.5
Gorden, P.6
|