Increasing circulating IGFBP1 levels improves insulin sensitivity, promotes nitric oxide production, lowers blood pressure, and protects against atherosclerosis

Diabetes

Volumn 61, Issue 4, 2012, Pages 915-924

  Rajwani, Adil ^a   Ezzat, Vivienne ^b   Smith, Jessica ^a   Yuldasheva, Nadira Y ^a   Duncan, Edward R ^b   Gage, Matthew ^a   Cubbon, Richard M ^a   Kahn, Matthew B ^a   Imrie, Helen ^a   Abbas, Afroze ^a   Viswambharan, Hema ^a   Aziz, Amir ^a   Sukumar, Piruthivi ^a   Vidal Puig, Antonio ^c   Sethi, Jaswinder K ^c   Xuan, Shouhong ^d   Shah, Ajay M ^b   Grant, Peter J ^a   Porter, Karen E ^a   Kearney, Mark T ^a   Wheatcroft, Stephen B ^a   more..

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d New York Presbyterian Morgan Stanley Children's Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; MESSENGER RNA; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SERINE; SOMATOMEDIN BINDING PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA PRESSURE; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; INSULIN RESISTANCE; INSULIN SENSITIVITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; VASODILATATION; WILD TYPE;

ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BLOOD PRESSURE; CELLS, CULTURED; DIABETES MELLITUS; ENDOTHELIAL CELLS; GENE DELETION; HUMANS; INSULIN RESISTANCE; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; MICE; MICE, TRANSGENIC; NITRIC OXIDE; OBESITY; RECEPTOR, INSULIN;

EID: 84859524836     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-0963     Document Type: Article

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