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Volumn 53, Issue 10, 2004, Pages 2645-2652

Preserved glucoregulation but attenuation of the vascular actions of insulin in mice heterozygous for knockout of the insulin receptor

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INSULIN RECEPTOR; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

EID: 4644337373     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.53.10.2645     Document Type: Article
Times cited : (61)

References (41)
  • 1
    • 0024026298 scopus 로고
    • Lilly Lecture: The triumvirate: Beta-cell, muscle, liver: A collusion responsible for NIDDM
    • DeFronzo RA: Lilly Lecture: the triumvirate: beta-cell, muscle, liver: a collusion responsible for NIDDM. Diabetes 37:667-687, 1988
    • (1988) Diabetes , vol.37 , pp. 667-687
    • DeFronzo, R.A.1
  • 2
    • 0345698971 scopus 로고    scopus 로고
    • Hyperinsulinemia predicts coronary heart disease risk in healthy middle-aged men: The 22-year follow-up results of the Helsinki Policemen Study
    • Pyorala M, Miettinen H, Laakso M, Pyorala K: Hyperinsulinemia predicts coronary heart disease risk in healthy middle-aged men: the 22-year follow-up results of the Helsinki Policemen Study. Circulation 98:398-404, 1998
    • (1998) Circulation , vol.98 , pp. 398-404
    • Pyorala, M.1    Miettinen, H.2    Laakso, M.3    Pyorala, K.4
  • 3
    • 0642333879 scopus 로고    scopus 로고
    • Increased incidence of coronary atherosclerosis in type 2 diabetes mellitus: Mechanisms and management
    • Hurst RT, Lee RW: Increased incidence of coronary atherosclerosis in type 2 diabetes mellitus: mechanisms and management. Ann Intern Med 139:824-834, 2003
    • (2003) Ann Intern Med , vol.139 , pp. 824-834
    • Hurst, R.T.1    Lee, R.W.2
  • 4
    • 0029977757 scopus 로고    scopus 로고
    • Obesity/insulin resistance is associated with endothelial dysfunction: Implications for the syndrome of insulin resistance
    • Steinberg HO, Chaker H, Leaming R, Johnson A, Brechtel G, Baron AD: Obesity/insulin resistance is associated with endothelial dysfunction: implications for the syndrome of insulin resistance. J Clin Invest 97:2601-2610, 1996
    • (1996) J Clin Invest , vol.97 , pp. 2601-2610
    • Steinberg, H.O.1    Chaker, H.2    Leaming, R.3    Johnson, A.4    Brechtel, G.5    Baron, A.D.6
  • 5
    • 0025292440 scopus 로고
    • Decreased effect of insulin to stimulate skeletal muscle blood flow in obese man: A novel mechanism for insulin resistance
    • Laakso M, Edelman SV, Brechtel G, Baron AD: Decreased effect of insulin to stimulate skeletal muscle blood flow in obese man: a novel mechanism for insulin resistance. J Clin Invest 85:1844-1852, 1990
    • (1990) J Clin Invest , vol.85 , pp. 1844-1852
    • Laakso, M.1    Edelman, S.V.2    Brechtel, G.3    Baron, A.D.4
  • 6
    • 0030007350 scopus 로고    scopus 로고
    • Impaired nitric oxide-mediated vasodilation in patients with non-insulin-dependent diabetes mellitus
    • Williams SB, Cusco JA, Roddy MA, Johnstone MT, Creager MA: Impaired nitric oxide-mediated vasodilation in patients with non-insulin-dependent diabetes mellitus. J Am Coll Cardiol 27:567-574, 1996
    • (1996) J Am Coll Cardiol , vol.27 , pp. 567-574
    • Williams, S.B.1    Cusco, J.A.2    Roddy, M.A.3    Johnstone, M.T.4    Creager, M.A.5
  • 7
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis: An inflammatory disease
    • Ross R: Atherosclerosis: an inflammatory disease. N Engl J Med 340:115-126, 1999
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 8
    • 0034681949 scopus 로고    scopus 로고
    • Endothelial dysfunction is detectable in young normotensive first-degree relatives of subjects with type 2 diabetes in association with insulin resistance
    • Balletshofer BM, Rittig K, Enderle MD, Volk A, Maerker E, Jacob S, Matthaei S, Rett K, Haring HU: Endothelial dysfunction is detectable in young normotensive first-degree relatives of subjects with type 2 diabetes in association with insulin resistance. Circulation 101:1780-1784, 2000
    • (2000) Circulation , vol.101 , pp. 1780-1784
    • Balletshofer, B.M.1    Rittig, K.2    Enderle, M.D.3    Volk, A.4    Maerker, E.5    Jacob, S.6    Matthaei, S.7    Rett, K.8    Haring, H.U.9
  • 9
    • 0033637747 scopus 로고    scopus 로고
    • Evidence for physiological coupling of insulin-mediated glucose metabolism and limb blood flow
    • Mather K, Laakso M, Edelman S, Hook G, Baron A: Evidence for physiological coupling of insulin-mediated glucose metabolism and limb blood flow. Am J Physiol Endocrinol Metab 279:E1264-E1270, 2000
    • (2000) Am J Physiol Endocrinol Metab , vol.279
    • Mather, K.1    Laakso, M.2    Edelman, S.3    Hook, G.4    Baron, A.5
  • 10
    • 0033542476 scopus 로고    scopus 로고
    • Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
    • Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher A: Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 399:601-605, 1999
    • (1999) Nature , vol.399 , pp. 601-605
    • Dimmeler, S.1    Fleming, I.2    Fisslthaler, B.3    Hermann, C.4    Busse, R.5    Zeiher, A.6
  • 12
    • 0034603858 scopus 로고    scopus 로고
    • Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells
    • Zeng G, Nystrom FH, Ravichandran LV, Cong LN, Kirby M, Mostowski H, Quon MJ: Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells. Circulation 101:1539-1545, 2000
    • (2000) Circulation , vol.101 , pp. 1539-1545
    • Zeng, G.1    Nystrom, F.H.2    Ravichandran, L.V.3    Cong, L.N.4    Kirby, M.5    Mostowski, H.6    Quon, M.J.7
  • 13
    • 0141671792 scopus 로고    scopus 로고
    • Molecular and physiologic actions of insulin related to production of nitric oxide in vascular endothelium
    • Vincent MA, Montagnani M, Quon MJ: Molecular and physiologic actions of insulin related to production of nitric oxide in vascular endothelium. Curr Diab Rep 3:279-288, 2003
    • (2003) Curr Diab Rep , vol.3 , pp. 279-288
    • Vincent, M.A.1    Montagnani, M.2    Quon, M.J.3
  • 14
    • 0036434431 scopus 로고    scopus 로고
    • Insulin regulation of glucose uptake: A complex interplay of intracellular signalling pathways
    • Khan AH, Pessin JE: Insulin regulation of glucose uptake: a complex interplay of intracellular signalling pathways. Diabetologia 45:1475-1483, 2002
    • (2002) Diabetologia , vol.45 , pp. 1475-1483
    • Khan, A.H.1    Pessin, J.E.2
  • 17
    • 0033966768 scopus 로고    scopus 로고
    • Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2
    • Kido Y, Burks DJ, Withers D, Bruning JC, Kahn CR, White MF, Accili D: Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2. J Clin Invest 105:199-205, 2000
    • (2000) J Clin Invest , vol.105 , pp. 199-205
    • Kido, Y.1    Burks, D.J.2    Withers, D.3    Bruning, J.C.4    Kahn, C.R.5    White, M.F.6    Accili, D.7
  • 18
    • 0034088143 scopus 로고    scopus 로고
    • Dysregulation of the insulin/IGF binding protein-1 axis in transgenic mice is associated with hyperinsulinemia and glucose intolerance
    • Crossey PA, Jones JS, Miell JP: Dysregulation of the insulin/IGF binding protein-1 axis in transgenic mice is associated with hyperinsulinemia and glucose intolerance. Diabetes 49:457-465, 2000
    • (2000) Diabetes , vol.49 , pp. 457-465
    • Crossey, P.A.1    Jones, J.S.2    Miell, J.P.3
  • 21
    • 1642300827 scopus 로고    scopus 로고
    • Opposing roles of p47phox in basal versus angiotensin II-stimulated alterations in vascular O2- production, vascular tone, and mitogen-activated protein kinase activation
    • Li JM, Wheatcroft S, Fan LM, Kearney MT, Shah AM: Opposing roles of p47phox in basal versus angiotensin II-stimulated alterations in vascular O2- production, vascular tone, and mitogen-activated protein kinase activation. Circulation 109:1307-1313, 2004
    • (2004) Circulation , vol.109 , pp. 1307-1313
    • Li, J.M.1    Wheatcroft, S.2    Fan, L.M.3    Kearney, M.T.4    Shah, A.M.5
  • 22
    • 0033788230 scopus 로고    scopus 로고
    • Metformin treatment corrects vascular insulin resistance in hypertension
    • Verma S, Yao L, Dumont AS, McNeill JH: Metformin treatment corrects vascular insulin resistance in hypertension. J Hypertens 18:1445-1450, 2000
    • (2000) J Hypertens , vol.18 , pp. 1445-1450
    • Verma, S.1    Yao, L.2    Dumont, A.S.3    McNeill, J.H.4
  • 23
    • 0030924055 scopus 로고    scopus 로고
    • Impaired insulin-induced attenuation of noradrenaline-mediated vasoconstriction in insulin-resistant obese Zucker rats
    • Walker AB, Dores J, Buckingham RE, Savage MW, Williams G: Impaired insulin-induced attenuation of noradrenaline-mediated vasoconstriction in insulin-resistant obese Zucker rats. Clinical Science 93:235-241, 1997
    • (1997) Clinical Science , vol.93 , pp. 235-241
    • Walker, A.B.1    Dores, J.2    Buckingham, R.E.3    Savage, M.W.4    Williams, G.5
  • 24
    • 0032993428 scopus 로고    scopus 로고
    • The thiazolidinedione rosiglitazone (BRL-49653) lowers blood pressure and protects against impairment of endothelial function in Zucker fatty rats
    • Walker AB, Chattington PD, Buckingham RE, Williams G: The thiazolidinedione rosiglitazone (BRL-49653) lowers blood pressure and protects against impairment of endothelial function in Zucker fatty rats. Diabetes 48:1448-1453, 1999
    • (1999) Diabetes , vol.48 , pp. 1448-1453
    • Walker, A.B.1    Chattington, P.D.2    Buckingham, R.E.3    Williams, G.4
  • 25
    • 0037154308 scopus 로고    scopus 로고
    • Pivotal role of a gp91(phox)-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice
    • Bendall JK, Cave AC, Heymes C, Gall N, Shah AM: Pivotal role of a gp91(phox)-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice. Circulation 105:293-296, 2002
    • (2002) Circulation , vol.105 , pp. 293-296
    • Bendall, J.K.1    Cave, A.C.2    Heymes, C.3    Gall, N.4    Shah, A.M.5
  • 27
    • 0037205457 scopus 로고    scopus 로고
    • Intracellular localization and preassembly of the NADPH oxidase complex in cultured endothelial cells
    • Li JM, Shah AM: Intracellular localization and preassembly of the NADPH oxidase complex in cultured endothelial cells. J Biol Chem 277:19952-19960, 2002
    • (2002) J Biol Chem , vol.277 , pp. 19952-19960
    • Li, J.M.1    Shah, A.M.2
  • 28
    • 0042388672 scopus 로고    scopus 로고
    • Flow-dependent regulation of endothelial nitric oxide synthase: Role of protein kinases
    • Boo YC, Jo H: Flow-dependent regulation of endothelial nitric oxide synthase: role of protein kinases. Am J Physiol Cell Physiol 285:C499-C508, 2003
    • (2003) Am J Physiol Cell Physiol , vol.285
    • Boo, Y.C.1    Jo, H.2
  • 29
    • 0042570843 scopus 로고    scopus 로고
    • Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance
    • Virkamaki A, Ueki K, Kahn CR: Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance. J Clin Invest 103:931-943, 1999
    • (1999) J Clin Invest , vol.103 , pp. 931-943
    • Virkamaki, A.1    Ueki, K.2    Kahn, C.R.3
  • 34
    • 0031857265 scopus 로고    scopus 로고
    • Insulin resistance in essential hypertension is related to plasma renin activity
    • Lind L, Reneland R, Andersson PE, Haenni A, Lithell H: Insulin resistance in essential hypertension is related to plasma renin activity. J Hum Hypertens 12:379-382, 1998
    • (1998) J Hum Hypertens , vol.12 , pp. 379-382
    • Lind, L.1    Reneland, R.2    Andersson, P.E.3    Haenni, A.4    Lithell, H.5
  • 35
    • 0025995364 scopus 로고
    • Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans
    • Anderson EA, Hoffman RP, Balon TW, Sinkey CA, Mark AL: Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans. J Clin Invest 87:2246-2252, 1991
    • (1991) J Clin Invest , vol.87 , pp. 2246-2252
    • Anderson, E.A.1    Hoffman, R.P.2    Balon, T.W.3    Sinkey, C.A.4    Mark, A.L.5
  • 37
    • 0031920445 scopus 로고    scopus 로고
    • Insulin-induced vasodilatation: Physiology or pharmacology?
    • Yld-Jarvinen H, Utriainen T: Insulin-induced vasodilatation: physiology or pharmacology? Diabetologia 41:369-379, 1998
    • (1998) Diabetologia , vol.41 , pp. 369-379
    • Yld-Jarvinen, H.1    Utriainen, T.2
  • 38
    • 85077348867 scopus 로고    scopus 로고
    • Insulin-mediated vasodilation: Why one's physiology could be the other's pharmacology
    • Steinberg HO, Baron AD: Insulin-mediated vasodilation: why one's physiology could be the other's pharmacology. Diabetologia 42:493-495, 1999
    • (1999) Diabetologia , vol.42 , pp. 493-495
    • Steinberg, H.O.1    Baron, A.D.2
  • 39
    • 0026656320 scopus 로고
    • Lilly Lecture: Molecular mechanisms of insulin resistance: Lessons from patients with mutations in the insulin-receptor gene
    • Taylor SI: Lilly Lecture: Molecular mechanisms of insulin resistance: lessons from patients with mutations in the insulin-receptor gene. Diabetes 41:1473-1490, 1992
    • (1992) Diabetes , vol.41 , pp. 1473-1490
    • Taylor, S.I.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.