D5 dopamine receptors enhance Zn2+-sensitive GABA(A) currents in striatal cholinergic interneurons through a PKA/PP1 cascade

Neuron

Volumn 19, Issue 5, 1997, Pages 1115-1126

  Yan, Zhen ^a   Surmeier, D James ^a  

^a UNIVERSITY OF TENNESSEE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; DOPAMINE 5 RECEPTOR; PHOSPHOPROTEIN PHOSPHATASE 1; ZINC; 4 AMINOBUTYRIC ACID RECEPTOR; DOPAMINE 1 RECEPTOR; DRD5 PROTEIN, RAT; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; CHOLINERGIC NERVE CELL; CONTROLLED STUDY; DEPHOSPHORYLATION; ENZYME ACTIVATION; ENZYME INHIBITION; INTERNEURON; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATE DEPENDENT LEARNING; ANIMAL; CHOLINERGIC NERVE; CORPUS STRIATUM; DRUG EFFECT; ELECTRIC CONDUCTIVITY; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; CHOLINERGIC FIBERS; CORPUS STRIATUM; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ELECTRIC CONDUCTIVITY; ENZYME ACTIVATION; INTERNEURONS; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PROTEIN KINASE C; RATS; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D5; RECEPTORS, GABA; RECEPTORS, GABA-A; ZINC;

EID: 0031279109     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(00)80402-X     Document Type: Article

References (67)

1. Allen, P., Ouimet, C., and Greengard, P. (1997). Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines. Proc. Natl. Acad. Sci. USA 94, 9956-9961.
2. Alexander, G.E., DeLong, M.R., and Strick, P.L. (1986). Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu. Rev. Neurosci. 9, 357-381.
3. Aosaki, T., Graybiel, A.M., and Kimura, M. (1994). Effect of the nigrostriatal dopamine system on acquired neural responses in the striaturn of behaving monkeys. Science 265, 412-415.
4. 2+ from brain tissue during activity. Nature 308, 734-736.
5. 2+ currents in acutely-isolated, adult rat neostriatal neurons. J. Neurosci. 14, 6667-6686.
6. Bartholini, G., Scatton, B., Worms, P., Zivkovic, B., and Lloyd, K.G. (1981). Interactions between GABA, dopamine, acetylcholine, and glutamate-containing neurons in the extrapyramidal and limbic systems. Adv. Biochem. Psychopharmacol. 30, 119-128.
7. 5 dopamine receptors in primate brain. J. Neurosci. 15, 7821-7836.
8. Bialojan, C., and Takai, A. (1988). Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics. Biochem. J. 256, 283-290.
9. Bolam, J.P., Ingham, C.A., Izzo, P.N., Levey, A.I., Rye, D.B., Smith, A.D., and Wainer, B.H. (1986). Substance P-containing terminals in synaptic contact with cholinergic neurons in the neostriatum and basal forebrain: a double immunocytochemical study in the rat. Brain Res. 397, 279-289.
10. Browning, M.D., Bureau, M., Dudek, E.M., and Olsen, R.W. (1990). Protein kinase C and cAMP-dependent protein kinase phosphorylate the beta subunit of the purified gamma-aminobutyric acid A receptor. Proc. Natl. Acad. Sci. USA 87, 1315-1318.
11. A receptor by cAMP-dependent protein kinase and by protein kinase C: analysis of the substrate domain. Neurochem. Res. 18, 95-100.
12. A receptor-activated current by norepinephrine in cerebellar Purkinje cells. Neuroscience 51, 951-960.
13. Chu, Y., Lee, E.Y., and Schlender, K.K. (1996). Activation of protein phosphatase 1. Formation of a metalloenzyme. J. Biol. Chem. 271, 2574-2577.
14. 2+. Neuron 5, 781-788.
15. Faux, M.C., and Scott, J.D. (1996). Molecular glue: kinase anchoring and scaffold proteins. Cell 85, 9-12.
16. Feigenspan, A., and Bormann, J. (1994). Facilitation of GABAergic signaling in the retina by receptors stimulating adenylate cyclase. Proc. Natl. Acad. Sci. USA 91, 10893-10897.
17. 5 dopamine receptor genes: a functional receptor and two pseudogenes. Proc. Natl. Acad. Sci. USA 88, 9175-9179.
18. Graybiel, A.M. (1990). Neurotransmitters and neuromodulators in the basal ganglia. Trends Neurosci. 13, 244-254.
19. Graybiel, A.M., Aosaki, T., Flaherty, A.W., and Kimura, M. (1994). The basal ganglia and adaptive motor control. Science 265, 1826-1831.
20. Grigorenko, E.V., and Yeh, H.H. (1994). Expression profiling of GABAA receptor beta-subunits in the rat retina. Vis. Neurosci. 11, 379-387.
21. Gustafson, E.L., Girault, J.A., Hemmings, H.C., Jr., Nairn, A.C., and Greengard, P. (1991). Immunocytochemical localization of phosphatase inhibitor-1 in rat brain. J. Comp. Neurol. 310, 170-188.
22. Heuschneider, G., and Schwartz, R.D. (1989). cAMP and forskolin decrease gamma-aminobutyric acid-gated chloride flux in rat brain synaptoneurosomes. Proc. Natl. Acad. Sci. USA 86, 2938-2942.
23. Hubbard, M.J., and Cohen, P. (1993). On target with a new mechanism for the regulation of protein phosphorylation. Trends Biochem. Sci. 18, 172-176.
24. Ishihara, H., Martin, B.L., Brautigan, D.L., Karaki, H., Ozaki, H., Kato, Y., Fusetani, N., Watabe, S., Hashimoto, K., Uemura, D., et al. (1989). Calyculin A and okadaic acid: inhibitors of protein phosphatase activity. Biochem. Biophys Res. Commun. 159, 871-877.
25. A channel responses to brief agonist pulses. Neuron 15, 181-191.
26. Kano, M., and Konnerth, A. (1992). Potentiation of GABA-mediated currents by cAMP-dependent protein kinase. Neuroreport 3, 563-566.
27. A receptor currents. J. Neurophysiol. 76, 2626-2634.
28. Kellenberger, S., Malherbe, P., and Sigel, E. (1992). Function of the alpha 1 beta 2 gamma 2S gamma-aminobutyric acid type A receptor is modulated by protein kinase C via multiple phosphorylation sites. J. Biol. Chem. 267, 25660-25663.
29. Kita, H. (1993). GABAergic circuits of the striatum. In Chemical Signaling in the Basal Ganglia, G.W. Arbuthnott and P.C. Emson, eds. (Oxford: Elsevier Science Publishers), pp. 51-72.
30. Klauck, T.M., Faux, M.C., Labudda, K., Langeberg, L.K., Jaken, S., and Scott, J.D. (1996). Coordination of three signaling enzymes by AKAP79, a mammalian scaffold protein. Science 271, 1589-1592.
31. Kofuji, P., Wang, J.B., Moss, S.J., Huganir, R.L., and Burt, D.R. (1991). Generation of two forms of the gamma-aminobutyric acidA receptor gamma 2-subunit in mice by alternative splicing. J. Neurochem. 56, 713-715.
32. A receptorfunction by protein kinase C phosphorylation. Neuron 12, 1081-1095.
33. Lehmann, J., and Langer, S.Z. (1983). The striatal cholinergic interneuron: synaptic target of dopaminergic terminals? Neuroscience 10, 1105-1120.
34. Leidenheimer, N.J. (1996). Effect of PKG activation on recombinant GABAA receptors. Brain Res. Mol. Brain Res. 42, 131-134.
35. Leidenheimer, N.J., Browning, M.D., Dunwiddie, T.V., Hahner, L.D., and Harris, R.A. (1990). Phosphorylation-independent effects of second messenger system modulators on gamma-aminobutyric acidA receptor complex function. Mol. Pharmacol. 38, 823-828.
36. Leidenheimer, N.J., McQuilkin, S.J., Hahner, L.D., Whiting, P., and Harris, R.A. (1992). Activation of protein kinase C selectively inhibits the gamma-aminobutyric acidA receptor: role of desensitization. Mol. Pharmacol. 41, 1116-1123.
37. 2 dopamine receptor gene expression by cholinergic neurons in the rat striatum. Neurosci. Lett. 117, 248-252.
38. Lin, Y.F., Angelotti, T.P., Dudek, E.M., Browning, M.D., and Macdonald, R.L. (1996). Enhancement of recombinant alpha 1 beta 1 gamma 2L gamma-aminobutyric acidA receptor whole-cell currents by protein kinase C is mediated through phosphorylation of both beta 1 and gamma 2L subunits. Mol. Pharmacol. 50, 185-195.
39. A receptor channels. Annu. Rev. Neurosci. 17, 569-602.
40. Martone, M.E., Armstrong, D.M., Young, S.J., and Groves, P.M. (1992). Ultrastructural examination of enkephalin and substance P input to cholinergic neurons within the rat neostriatum. Brain Res. 594, 253-262.
41. McGeer, P.L., McGeer, E.G., Singh, V.K., and Chase, W.H. (1974). Choline acetyltransferase localization in the central nervous system by immunohistochemistry. Brain Res. 81, 373-379.
42. McGeer, P.L., McGeer, E.G., and Hattori, T. (1977). Dopamine-acetylcholine-GABA neuronal linkages in the extrapyramidal and limbic systems. Adv. Biochem. Psychopharmacol. 16, 397-402.
43. A-receptor subtypes really occur in the brain? Trends Neurosci. 19, 139-143.
44. Mengual, E., Casanovas-Aguilar, C., Perez-Clausell, J., and Gimenez-Amaya, J.M. (1995). Heterogeneous and compartmental distribution of zinc in the striatum and globus pallidus of the rat. Neuroscience 66, 523-537.
45. Moss, S.J., Doherty, C.A., and Huganir, R.L. (1992a). Identification of the cAMP-dependent protein kinase and protein kinase C phosphorylation sites within the major intracellular domains of the beta 1, gamma 2S, and gamma 2L subunits of the gamma-aminobutyric acid type A receptor. J. Biol. Chem. 267, 14470-14476.
46. A receptors by cAMP-dependent protein phosphorylation. Science 257, 661-665.
47. A receptor current in mouse spinal neurons. Neuron 5, 789-796.
48. A receptor research. Synapse 21, 189-274.
49. Rosenmund, C., Carr, D.W., Bergeson, S.E., Nilaver, G., Scott, J.D., and Westbrook, G.L. (1994). Anchoring of protein kinase A is required for modulation of AMPA/kainate receptors on hippocampal neurons. Nature 368, 853-856.
50. A receptor subunits: role of the delta subunit. J. Neurosci. 14, 7077-7086.
51. A receptors. Eur. J. Neurosci. 5, 1042-1049.
52. Schultz, W., Apicella, P., and Ljungberg, T. (1993). Responses of monkey dopamine neurons to reward and conditioned stimuli during successive steps of learning a delayed response task. J. Neurosci. 13, 900-913.
53. Schwartz, R.D., Heuschneider, G., Edgar, P.P., and Cohn, J.A. (1991). cAMP analogs inhibit gamma-aminobutyric acid-gated chloride flux and activate protein kinase A in brain synaptoneurosomes. Mol. Pharmacol. 39, 370-375.
54. Sibley, D.R. (1995). Molecular biology of dopamine receptors. In Molecular and Cellular Mechanisms of Neostriatal Function, M.A. Ariano and D.J. Surmeier, eds. (Austin, TX: R.G. Landes), pp. 255-272.
55. 1. Nature 350, 614-619.
56. 1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons. Neuron 14, 385-397.
57. Surmeier, D.J., Song, W.-J., and Yan, Z. (1996). Coordinated expression of dopamine receptors in neostriatal medium spiny neurons. J. Neurosci. 16, 6579-6591.
58. Sweetnam, P.M., Lloyd, J., Gallombardo, P., Malison, R.T., Gallager, D.W., Tallman, J.F., and Nestler, E.J. (1988). Phosphorylation of the GABAa/benzodiazepine receptor alpha subunit by a receptor-associated protein kinase. J. Neurochem. 51, 1274-1284.
59. Tehrani, M.H., and Barnes, E.M., Jr. (1995). Reduced function of gamma-aminobutyric acidA receptors in tottering mouse brain: role of cAMP-dependent protein kinase. Epilepsy Res. 22, 13-21.
60. Tukey, J.W. (1977). Exploratory Data Analysis. (Menlo Park, CA: Addison-Wesley).
61. Vincent, S.R., and Semba, K. (1989). A heavy metal marker of the developing striatal mosaic. Brain Res. Dev. Brain Res. 45, 155-159.
62. Walaas, S.I., and Greengard, P. (1991). Protein phosphorylation and neuronal function. Pharmacol. Rev. 43, 299-349.
63. A receptor currents. Neuroreport 6, 461-464.
64. Whiting, P., McKernan, R.M., and Iversen, L.L. (1990). Another mechanism for creating diversity in gamma-aminobutyrate type A receptors: RNA splicing directs expression of two forms of gamma 2 phosphorylation site. Proc. Natl. Acad. Sci. USA 87, 9966-9970.
65. Wilson, C.J., Chang, H.T., and Kitai, S.T. (1990). Firing patterns and synaptic potentials of identified giant aspiny interneurons in the rat neostriatum. J. Neurosci. 10, 508-519.
66. A receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon. J. Neurosci. 12, 1040-1062.
67. 2+ currents in rat neostriatal cholinergic interneurons through a membrane-delimited, protein kinase C-insensitive pathway. J. Neurophysiol. 78, 1003-1015.