Membrane type 1 matrix metalloproteinase (MT1-MMP) ubiquitination at Lys581 increases cellular invasion through type I collagen

Journal of Biological Chemistry

Volumn 287, Issue 14, 2012, Pages 11533-11545

  Eisenach, Patricia A ^a   De Sampaio, Pedro Correâ ^a   Murphy, Gillian ^a   Roghi, Christian ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR MIGRATION; EXPRESSION LEVELS; INTRACELLULAR DOMAIN; LYSINE RESIDUES; MEMBRANE TYPE-1 MATRIX METALLOPROTEINASE; METALLOPROTEINASES; PERICELLULAR PROTEOLYSIS; POST-TRANSLATIONAL MODIFICATIONS; SRC FAMILY; TRANSMEMBRANES; TYPE I COLLAGEN; UBIQUITINATION;

AMINO ACIDS; DIAGNOSIS; PHOSPHORYLATION;

ENZYME ACTIVITY;

COLLAGEN TYPE 1; MATRIX METALLOPROTEINASE 14; PROTEIN TYROSINE KINASE; UBIQUITIN PROTEIN LIGASE NEDD4;

ARTICLE; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN TRANSPORT; UBIQUITINATION;

CELL LINE, TUMOR; CELL MOVEMENT; COLLAGEN TYPE I; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INTRACELLULAR SPACE; LYSINE; MATRIX METALLOPROTEINASE 14; MUTAGENESIS, SITE-DIRECTED; MUTATION; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS PP60(C-SRC); UBIQUITINATION;

EID: 84859498065     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.306340     Document Type: Article

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