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Volumn 102, Issue 9, 2003, Pages 3262-3269

Amoeboid shape change and contact guidance: T-lymphocyte crawling through fibrillar collagen is independent of matrix remodeling by MMPs and other proteases

Author keywords

[No Author keywords available]

Indexed keywords

ADAM 10 PROTEIN; ADAM 11 PROTEIN; ADAM 15 PROTEIN; ADAM 9 PROTEIN; CATHEPSIN L; CHONDROITIN SULFATE; CYSTEINE PROTEINASE; FIBRILLAR COLLAGEN; FLUORESCEIN ISOTHIOCYANATE; GELATINASE B; HYALURONIC ACID; LEUPEPTIN; MARIMASTAT; MATRIX METALLOPROTEINASE; MESSENGER RNA; N [N (3 CARBOXYOXIRANE 2 CARBONYL)LEUCYL]AGMATINE; PEPSTATIN; PROTEINASE INHIBITOR; SERINE PROTEINASE; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UNCLASSIFIED DRUG; UROKINASE; UROKINASE RECEPTOR;

EID: 0142245603     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2002-12-3791     Document Type: Article
Times cited : (357)

References (48)
  • 1
    • 0034609968 scopus 로고    scopus 로고
    • T-cell function and migration: Two sides of the same coin
    • von Andrian UH, Mackay CR. T-cell function and migration: two sides of the same coin. N Engl J Med. 2000;343:1020-1034.
    • (2000) N Engl J Med , vol.343 , pp. 1020-1034
    • Von Andrian, U.H.1    Mackay, C.R.2
  • 2
    • 0024147085 scopus 로고
    • Chemotaxis in eukaryotic cells: A focus on leukocytes and Dictyostelium
    • Devreotes PN, Zigmond SH. Chemotaxis in eukaryotic cells: a focus on leukocytes and Dictyostelium. Annu Rev Cell Biol. 1988;4:649-686.
    • (1988) Annu Rev Cell Biol , vol.4 , pp. 649-686
    • Devreotes, P.N.1    Zigmond, S.H.2
  • 3
    • 0034792774 scopus 로고    scopus 로고
    • Leukocyte crawling through extracellular matrix and the Dictyostelium paradigm of movement-lessons from a social amoeba
    • Friedl P, Borgmann S, Brocker EB. Leukocyte crawling through extracellular matrix and the Dictyostelium paradigm of movement-lessons from a social amoeba. J Leukoc Biol. 2001;70:491-509.
    • (2001) J Leukoc Biol , vol.70 , pp. 491-509
    • Friedl, P.1    Borgmann, S.2    Brocker, E.B.3
  • 4
    • 0020539262 scopus 로고
    • Lymphocyte migration into three-dimensional collagen matrices: A quantitative study
    • Schor SL, Allen TD, Winn B. Lymphocyte migration into three-dimensional collagen matrices: a quantitative study. J Cell Biol. 1983;96:1089-1096.
    • (1983) J Cell Biol , vol.96 , pp. 1089-1096
    • Schor, S.L.1    Allen, T.D.2    Winn, B.3
  • 5
    • 0031253730 scopus 로고    scopus 로고
    • Differential requirement of protein tyrosine kinases and protein kinase C in the regulation of T cell locomotion in three-dimensional collagen matrices
    • Entschladen F, Niggemann B, Zänker KS, Friedl P. Differential requirement of protein tyrosine kinases and protein kinase C in the regulation of T cell locomotion in three-dimensional collagen matrices. J Immunol. 1997;159:3203-3210.
    • (1997) J Immunol , vol.159 , pp. 3203-3210
    • Entschladen, F.1    Niggemann, B.2    Zänker, K.S.3    Friedl, P.4
  • 6
    • 0031903617 scopus 로고    scopus 로고
    • - T lymphocytes migrating in three-dimensional collagen lattices lack focal adhesions and utilize beta1 integrin-independent strategies for polarization, interaction with collagen fibers and locomotion
    • - T lymphocytes migrating in three-dimensional collagen lattices lack focal adhesions and utilize beta1 integrin-independent strategies for polarization, interaction with collagen fibers and locomotion. Eur J Immunol. 1998;28:2331-2343.
    • (1998) Eur J Immunol , vol.28 , pp. 2331-2343
    • Friedl, P.1    Entschladen, F.2    Conrad, C.3    Niggemann, B.4    Zanker, K.S.5
  • 7
    • 18344384036 scopus 로고    scopus 로고
    • Betal integrin is not essential for hematopoiesis but is necessary for the T cell-dependent IgM antibody response
    • Brakebusch C, Fillatreau S, Potocnik AJ, et al. Betal integrin is not essential for hematopoiesis but is necessary for the T cell-dependent IgM antibody response. Immunity. 2002;16:465-477.
    • (2002) Immunity , vol.16 , pp. 465-477
    • Brakebusch, C.1    Fillatreau, S.2    Potocnik, A.J.3
  • 8
    • 0032400495 scopus 로고    scopus 로고
    • Cell migration strategies in 3-D extracellular matrix: Differences in morphology, cell matrix interactions, and integrin function
    • Friedl P, Zanker KS, Bröcker EB. Cell migration strategies in 3-D extracellular matrix: differences in morphology, cell matrix interactions, and integrin function. Microsc Res Tech. 1998;43:369-378.
    • (1998) Microsc Res Tech , vol.43 , pp. 369-378
    • Friedl, P.1    Zanker, K.S.2    Bröcker, E.B.3
  • 9
    • 0038049137 scopus 로고    scopus 로고
    • Tumour cell invasion and migration: Diversity and escape mechanisms
    • Friedl P, Wolf K. Tumour cell invasion and migration: diversity and escape mechanisms. Nature Rev Cancer. 2003;3:362-374.
    • (2003) Nature Rev Cancer , vol.3 , pp. 362-374
    • Friedl, P.1    Wolf, K.2
  • 10
    • 0033769059 scopus 로고    scopus 로고
    • T cell migration in three-dimensional extracellular matrix: Guidance by polarity and sensations
    • Friedl P, Brocker EB. T cell migration in three-dimensional extracellular matrix: guidance by polarity and sensations. Dev Immunol. 2000;7:249-266.
    • (2000) Dev Immunol , vol.7 , pp. 249-266
    • Friedl, P.1    Brocker, E.B.2
  • 12
    • 0030791315 scopus 로고    scopus 로고
    • Transmembrane/cytoplasmic domain-mediated membrane type 1 -matrix metalloprotease docking to invadopodia is required for cell invasion
    • Nakahara H, Howard L, Thompson EW, et al. Transmembrane/cytoplasmic domain-mediated membrane type 1 -matrix metalloprotease docking to invadopodia is required for cell invasion. Proc Natl Acad Sci U S A. 1997;94:7959-7964.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 7959-7964
    • Nakahara, H.1    Howard, L.2    Thompson, E.W.3
  • 14
    • 0034665315 scopus 로고    scopus 로고
    • Bioactive proteinase 3 on the cell surface of human neutrophils: Quantification, catalytic activity, and susceptibility to inhibition
    • Campbell EJ, Campbell MA, Owen CA. Bioactive proteinase 3 on the cell surface of human neutrophils: quantification, catalytic activity, and susceptibility to inhibition. J Immunol. 2000;165:3366-3374.
    • (2000) J Immunol , vol.165 , pp. 3366-3374
    • Campbell, E.J.1    Campbell, M.A.2    Owen, C.A.3
  • 15
    • 0031961853 scopus 로고    scopus 로고
    • Oscillatory pericellular proteolysis and oxidant deposition during neutrophil locomotion
    • Kindzelskii AL, Zhou MJ, Haugland RP, Boxer LA, Petty HR. Oscillatory pericellular proteolysis and oxidant deposition during neutrophil locomotion. Biophys J. 1998;74:90-97.
    • (1998) Biophys J , vol.74 , pp. 90-97
    • Kindzelskii, A.L.1    Zhou, M.J.2    Haugland, R.P.3    Boxer, L.A.4    Petty, H.R.5
  • 16
    • 0032820711 scopus 로고    scopus 로고
    • Proteolysis and cell migration: Creating a path?
    • Murphy G, Gavrilovic J. Proteolysis and cell migration: creating a path? Curr Opin Cell Biol. 1999;11:614-621.
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 614-621
    • Murphy, G.1    Gavrilovic, J.2
  • 17
    • 0033056463 scopus 로고    scopus 로고
    • The cell biology of leukocyte-mediated proteolysis
    • Owen CA, Campbell EJ. The cell biology of leukocyte-mediated proteolysis. J Leukoc Biol. 1999;65:137-150.
    • (1999) J Leukoc Biol , vol.65 , pp. 137-150
    • Owen, C.A.1    Campbell, E.J.2
  • 18
    • 0037455576 scopus 로고    scopus 로고
    • Compensation mechanism in tumor cell migration: Mesenchymal-amoeboid transition after blocking of pericellular proteolysis
    • Wolf K, Mazo I, Leung H, Engelke K, et al. Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis. J Cell Biol. 2003;160:267-277.
    • (2003) J Cell Biol , vol.160 , pp. 267-277
    • Wolf, K.1    Mazo, I.2    Leung, H.3    Engelke, K.4
  • 19
    • 0035947675 scopus 로고    scopus 로고
    • Matrix-dependent proteolysis of surface transglutaminase by membrane-type metalloproteinase regulates cancer cell adhesion and locomotion
    • Belkin AM, Akimov SS, Zaritskaya LS, Ratnikov BI, Deryugina EI, Strongin AY. Matrix-dependent proteolysis of surface transglutaminase by membrane-type metalloproteinase regulates cancer cell adhesion and locomotion. J Biol Chem. 2001;276:18415-18422.]
    • (2001) J Biol Chem , vol.276 , pp. 18415-18422
    • Belkin, A.M.1    Akimov, S.S.2    Zaritskaya, L.S.3    Ratnikov, B.I.4    Deryugina, E.I.5    Strongin, A.Y.6
  • 20
    • 0034472617 scopus 로고    scopus 로고
    • Matrix metalloproteinases in tumor invasion and metastasis
    • Stamenkovic I. Matrix metalloproteinases in tumor invasion and metastasis. Semin Cancer Biol. 2000;10:415-433.
    • (2000) Semin Cancer Biol , vol.10 , pp. 415-433
    • Stamenkovic, I.1
  • 21
    • 0032529241 scopus 로고    scopus 로고
    • Remodeling of collagen matrix by human tumor cells requires activation and cell surface association of matrix metalloproteinase-2
    • Deryugina EI, Bourdon MA, Reisfeld RA, Strongin A. Remodeling of collagen matrix by human tumor cells requires activation and cell surface association of matrix metalloproteinase-2. Cancer Res. 1998;58:3743-3750.
    • (1998) Cancer Res , vol.58 , pp. 3743-3750
    • Deryugina, E.I.1    Bourdon, M.A.2    Reisfeld, R.A.3    Strongin, A.4
  • 22
    • 0029764639 scopus 로고    scopus 로고
    • Regulation of integrin function by the urokinase receptor
    • Wei Y, Lukashev M, Simon DI, et al. Regulation of integrin function by the urokinase receptor. Science. 1996;273:1551-1555.
    • (1996) Science , vol.273 , pp. 1551-1555
    • Wei, Y.1    Lukashev, M.2    Simon, D.I.3
  • 23
    • 0036568954 scopus 로고    scopus 로고
    • Matrix metalloproteinases 9 and 2 are necessary for the migration of Langerhans cells and dermal dendritic cells from human and murine skin
    • Ratzinger G, Stoitzner P, Ebner S, et al. Matrix metalloproteinases 9 and 2 are necessary for the migration of Langerhans cells and dermal dendritic cells from human and murine skin. J Immunol. 2002;168:4361-4371.
    • (2002) J Immunol , vol.168 , pp. 4361-4371
    • Ratzinger, G.1    Stoitzner, P.2    Ebner, S.3
  • 24
    • 0030765248 scopus 로고    scopus 로고
    • Expression of several matrix metalloproteinase genes in human monocytic cells
    • Machein U, Conca W. Expression of several matrix metalloproteinase genes in human monocytic cells. Adv Exp Med Biol. 1997;421:247-251.
    • (1997) Adv Exp Med Biol , vol.421 , pp. 247-251
    • Machein, U.1    Conca, W.2
  • 26
    • 0028860849 scopus 로고
    • Stimulation of matrix- metalloproteinase-dependent migration of T cells by eicosanoids
    • Leppert D, Hauser SL, Kishiyama JL, An S, Zeng L, Goetzl EJ. Stimulation of matrix- metalloproteinase-dependent migration of T cells by eicosanoids. FASEB J. 1995;1473-1481.
    • (1995) FASEB J , pp. 1473-1481
    • Leppert, D.1    Hauser, S.L.2    Kishiyama, J.L.3    An, S.4    Zeng, L.5    Goetzl, E.J.6
  • 27
    • 0031065191 scopus 로고    scopus 로고
    • Plasmin-induced proteolysis of tenascin-C: Modulation by T lymphocyte-derived urokinase-type plasminogen activator and effect on T lymphocyte adhesion, activation, and cell clustering
    • Gundersen D, Tran-Thang C, Sordat B, Mourali F, Ruegg C. Plasmin-induced proteolysis of tenascin-C: modulation by T lymphocyte-derived urokinase-type plasminogen activator and effect on T lymphocyte adhesion, activation, and cell clustering. J Immunol. 1997;158:1051-1060.
    • (1997) J Immunol , vol.158 , pp. 1051-1060
    • Gundersen, D.1    Tran-Thang, C.2    Sordat, B.3    Mourali, F.4    Ruegg, C.5
  • 28
    • 0029041446 scopus 로고
    • T cell gelatinases mediate basement membrane transmigration in vitro
    • Leppert D, Waubant E, Galardy R, Bunnett NW, Hauser SL. T cell gelatinases mediate basement membrane transmigration in vitro. J Immunol. 1995;154:4379-4389.
    • (1995) J Immunol , vol.154 , pp. 4379-4389
    • Leppert, D.1    Waubant, E.2    Galardy, R.3    Bunnett, N.W.4    Hauser, S.L.5
  • 30
    • 0036587673 scopus 로고    scopus 로고
    • Neutrophils from MMP-9- or neutrophil elastase-deficient mice show no defect in transendothelial migration under flow in vitro
    • Allport JR, Lim YC, Shipley JM, et al. Neutrophils from MMP-9- or neutrophil elastase-deficient mice show no defect in transendothelial migration under flow in vitro. J Leukoc Biol. 2002;71:821-828.
    • (2002) J Leukoc Biol , vol.71 , pp. 821-828
    • Allport, J.R.1    Lim, Y.C.2    Shipley, J.M.3
  • 31
    • 0033143782 scopus 로고    scopus 로고
    • Neutrophil emigration in the lungs, peritoneum, and skin does not require gelatinase B
    • Betsuyaku T, Shipley JM, Liu Z, Senior RM. Neutrophil emigration in the lungs, peritoneum, and skin does not require gelatinase B. Am J Respir Cell Mol Biol. 1999;20:1303-1309.
    • (1999) Am J Respir Cell Mol Biol , vol.20 , pp. 1303-1309
    • Betsuyaku, T.1    Shipley, J.M.2    Liu, Z.3    Senior, R.M.4
  • 32
    • 0033145530 scopus 로고    scopus 로고
    • Migration of neutrophils across human pulmonary endothelial cells is not blocked by matrix metalloproteinase or serine protease inhibitors
    • Mackarel AJ, Cottell DC, Russell KJ, FitzGerald MX, O'Connor CM. Migration of neutrophils across human pulmonary endothelial cells is not blocked by matrix metalloproteinase or serine protease inhibitors. Am J Respir Cell Mol Biol. 1999;20:1209-1219.
    • (1999) Am J Respir Cell Mol Biol , vol.20 , pp. 1209-1219
    • Mackarel, A.J.1    Cottell, D.C.2    Russell, K.J.3    FitzGerald, M.X.4    O'Connor, C.M.5
  • 33
    • 0033666324 scopus 로고    scopus 로고
    • Antigen presentation in three-dimensional extracellular matrix: Interactions of T cells with dendritic cells are dynamic, short lived, and sequential
    • Gunzer M, Schäfer A, Borgmann S, et al. Antigen presentation in three-dimensional extracellular matrix: interactions of T cells with dendritic cells are dynamic, short lived, and sequential. Immunity. 2000;13:323-332.
    • (2000) Immunity , vol.13 , pp. 323-332
    • Gunzer, M.1    Schäfer, A.2    Borgmann, S.3
  • 34
    • 0029073708 scopus 로고
    • T Lymphocyte locomotion in a three-dimensional collagen matrix: Expression and function of cell adhesion molecules
    • Friedl P, Noble PB, Zänker KS. T Lymphocyte locomotion in a three-dimensional collagen matrix: expression and function of cell adhesion molecules. J Immunol. 1995;154:4973-4985.
    • (1995) J Immunol , vol.154 , pp. 4973-4985
    • Friedl, P.1    Noble, P.B.2    Zänker, K.S.3
  • 35
    • 0032834211 scopus 로고    scopus 로고
    • Functional hierarchy of simultaneously expressed adhesion receptors: Integrin alpha2beta1 but not CD44 mediates MV3 melanoma cell migration and matrix reorganization within three-dimensional hyaluronan-containing collagen matrices
    • Maaser K, Wolf K, Klein CE, et al. Functional hierarchy of simultaneously expressed adhesion receptors: integrin alpha2beta1 but not CD44 mediates MV3 melanoma cell migration and matrix reorganization within three-dimensional hyaluronan-containing collagen matrices. Mol Biol Cell 1999;10:3067-3079.
    • (1999) Mol Biol Cell , vol.10 , pp. 3067-3079
    • Maaser, K.1    Wolf, K.2    Klein, C.E.3
  • 36
    • 0033525037 scopus 로고    scopus 로고
    • Metalloprotease-disintegrin MDC9: Intracellular maturation and catalytic activity
    • Roghani M, Becherer JD, Moss ML, et al. Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity. J Biol Chem. 1999;274:3531-3540.
    • (1999) J Biol Chem , vol.274 , pp. 3531-3540
    • Roghani, M.1    Becherer, J.D.2    Moss, M.L.3
  • 37
    • 0030913972 scopus 로고    scopus 로고
    • Migration of highly aggressive MV3 melanoma cells in 3-dimensional collagen lattices results in local matrix reorganization and shedding of alpha2 and betal integrins and CD44
    • Friedl P, Maaser K, Klein CE, Niggemann B, Krohne G, Zanker KS. Migration of highly aggressive MV3 melanoma cells in 3-dimensional collagen lattices results in local matrix reorganization and shedding of alpha2 and betal integrins and CD44. Cancer Res. 1997;57:2061-2070.
    • (1997) Cancer Res , vol.57 , pp. 2061-2070
    • Friedl, P.1    Maaser, K.2    Klein, C.E.3    Niggemann, B.4    Krohne, G.5    Zanker, K.S.6
  • 38
    • 0000558160 scopus 로고
    • On the locomotion of the polymorphonuclear neutrophiles of the rat in autoplasma cultures
    • Lewis WH. On the locomotion of the polymorphonuclear neutrophiles of the rat in autoplasma cultures. Bull Johns Hopkins Hosp. 1934;4,273-279.
    • (1934) Bull Johns Hopkins Hosp , vol.4 , pp. 273-279
    • Lewis, W.H.1
  • 39
    • 0029585289 scopus 로고
    • Collagen and collagenase gene expression in three-dimensional collagen lattices are differentially regulated by alpha 1 beta 1 and alpha 2 beta 1 integrins
    • Langholz O, Rockel D, Mauch C, et al. Collagen and collagenase gene expression in three-dimensional collagen lattices are differentially regulated by alpha 1 beta 1 and alpha 2 beta 1 integrins. J Cell Biol. 1995;131:1903-1915.
    • (1995) J Cell Biol , vol.131 , pp. 1903-1915
    • Langholz, O.1    Rockel, D.2    Mauch, C.3
  • 40
    • 0032883939 scopus 로고    scopus 로고
    • Fibronectin upregulates gelatinase B (MMP-9) and induces coordinated expression of gelatinase A (MMP-2) and its activator MT1-MMP (MMP-14) by human T lymphocyte cell lines: A process repressed through RAS/MAP kinase signaling pathways
    • Esparza J, Vilardell C, Calvo J, et al. Fibronectin upregulates gelatinase B (MMP-9) and induces coordinated expression of gelatinase A (MMP-2) and its activator MT1-MMP (MMP-14) by human T lymphocyte cell lines: a process repressed through RAS/MAP kinase signaling pathways. Blood. 1999;94:2754-2766.
    • (1999) Blood , vol.94 , pp. 2754-2766
    • Esparza, J.1    Vilardell, C.2    Calvo, J.3
  • 41
    • 0027509798 scopus 로고
    • Participation of cathepsin L on bone resorption
    • Kakegawa H, Nikawa T, Tagami K, et al. Participation of cathepsin L on bone resorption. FEBS Lett. 1993;321:247-250.
    • (1993) FEBS Lett , vol.321 , pp. 247-250
    • Kakegawa, H.1    Nikawa, T.2    Tagami, K.3
  • 42
    • 0031025218 scopus 로고    scopus 로고
    • Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules
    • Ohuchi E, Imai K, Fujii Y, Sato H, Seiki M, Okada Y. Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules. J Biol Chem. 1997;272:2446-2451.
    • (1997) J Biol Chem , vol.272 , pp. 2446-2451
    • Ohuchi, E.1    Imai, K.2    Fujii, Y.3    Sato, H.4    Seiki, M.5    Okada, Y.6
  • 43
  • 44
    • 0031044473 scopus 로고    scopus 로고
    • Dynamic imaging of neutrophil migration in three dimensions: Mechanical interactions between cells and matrix
    • Mandeville JT, Lawson MA, Maxfield FR. Dynamic imaging of neutrophil migration in three dimensions: mechanical interactions between cells and matrix. J Leukoc Biol. 1997;61:188-200.
    • (1997) J Leukoc Biol , vol.61 , pp. 188-200
    • Mandeville, J.T.1    Lawson, M.A.2    Maxfield, F.R.3
  • 45
    • 0020534491 scopus 로고
    • The influence of contact guidance on chemotaxis of human neutrophil leukocytes
    • Wilkinson PC, Lackie JM. The influence of contact guidance on chemotaxis of human neutrophil leukocytes. Exp Cell Res. 1983;145:255-264.
    • (1983) Exp Cell Res , vol.145 , pp. 255-264
    • Wilkinson, P.C.1    Lackie, J.M.2
  • 46
    • 0030853612 scopus 로고    scopus 로고
    • Migration of dendritic cells in 3D-collagen lattices: Visualisation of dynamic interactions with the substratum and the distribution of surface structures via a novel confocal reflection imaging technique
    • Gunzer M, Kämpgen E, Bröcker E-B, Zänker KS, Friedl P. Migration of dendritic cells in 3D-collagen lattices: visualisation of dynamic interactions with the substratum and the distribution of surface structures via a novel confocal reflection imaging technique. Adv Exp Med Biol. 1997;417:97-103.
    • (1997) Adv Exp Med Biol , vol.417 , pp. 97-103
    • Gunzer, M.1    Kämpgen, E.2    Bröcker, E.-B.3    Zänker, K.S.4    Friedl, P.5
  • 47
    • 0037192458 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
    • Coussens LM, Fingleton B, Matrisian LM. Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science. 2002;295:2387-2392.
    • (2002) Science , vol.295 , pp. 2387-2392
    • Coussens, L.M.1    Fingleton, B.2    Matrisian, L.M.3
  • 48
    • 0037036142 scopus 로고    scopus 로고
    • Two-photon imaging of lymphocyte motility and antigen response in intact lymph node
    • Miller MJ, Wei SH, Parker I, Cahalan MD. Two-photon imaging of lymphocyte motility and antigen response in intact lymph node. Science. 2002;296:1869-1873.
    • (2002) Science , vol.296 , pp. 1869-1873
    • Miller, M.J.1    Wei, S.H.2    Parker, I.3    Cahalan, M.D.4


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