-
1
-
-
0037315085
-
Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice
-
Aasum E, Hafstad AD, Severson DL, Larsen TS. Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice. Diabetes 52: 434-441, 2003.
-
(2003)
Diabetes
, vol.52
, pp. 434-441
-
-
Aasum, E.1
Hafstad, A.D.2
Severson, D.L.3
Larsen, T.S.4
-
2
-
-
0028284974
-
Regulation of glucose utilization during the inhibition of fatty acid oxidation in rat myocytes
-
Abdel-Aleem S, Li X, Anstadt MP, Perez-Tamayo RA, Lowe JE. Regulation of glucose utilization during the inhibition of fatty acid oxidation in rat myocytes. Horm Metab Res 26: 88-91, 1994.
-
(1994)
Horm Metab Res
, vol.26
, pp. 88-91
-
-
Abdel-Aleem, S.1
Li, X.2
Anstadt, M.P.3
Perez-Tamayo, R.A.4
Lowe, J.E.5
-
3
-
-
34548448413
-
Two phases of palmitate-induced insulin resistance in skeletal muscle: Impaired GLUT4 translocation is followed by a reduced GLUT4 intrinsic activity
-
Alkhateeb H, Chabowski A, Glatz JF, Luiken JF, Bonen A. Two phases of palmitate-induced insulin resistance in skeletal muscle: impaired GLUT4 translocation is followed by a reduced GLUT4 intrinsic activity. Am J Physiol Endocrinol Metab 293: E783-E793, 2007.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.293
-
-
Alkhateeb, H.1
Chabowski, A.2
Glatz, J.F.3
Luiken, J.F.4
Bonen, A.5
-
4
-
-
33745684376
-
AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B
-
Bertrand L, Ginion A, Beauloye C, Hebert AD, Guigas B, Hue L, Vanoverschelde JL. AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B. Am J Physiol Heart Circ Physiol 291: H239-H250, 2006.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.291
-
-
Bertrand, L.1
Ginion, A.2
Beauloye, C.3
Hebert, A.D.4
Guigas, B.5
Hue, L.6
Vanoverschelde, J.L.7
-
5
-
-
77950788493
-
Shedding light on the enigma of myocardial lipotoxicity: The involvement of known and putative regulators of fatty acid storage and mobilization
-
Brindley DN, Kok BP, Kienesberger PC, Lehner R, Dyck JR. Shedding light on the enigma of myocardial lipotoxicity: the involvement of known and putative regulators of fatty acid storage and mobilization. Am J Physiol Endocrinol Metab 298: E897-E908, 2010.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.298
-
-
Brindley, D.N.1
Kok, B.P.2
Kienesberger, P.C.3
Lehner, R.4
Dyck, J.R.5
-
6
-
-
12344329352
-
Suppressor of cytokine signaling-3 Provides a novel interface in the cross-talk between angiotensin II and insulin signaling systems
-
Calegari VC, Alves M, Picardi PK, Inoue RY, Franchini KG, Saad MJ, Velloso LA. Suppressor of cytokine signaling-3 Provides a novel interface in the cross-talk between angiotensin II and insulin signaling systems. Endocrinology 146: 579-588, 2005.
-
(2005)
Endocrinology
, vol.146
, pp. 579-588
-
-
Calegari, V.C.1
Alves, M.2
Picardi, P.K.3
Inoue, R.Y.4
Franchini, K.G.5
Saad, M.J.6
Velloso, L.A.7
-
7
-
-
0034691172
-
GLUT8 is a glucose transporter responsible for insulin-stimulated glucose uptake in the blastocyst
-
Carayannopoulos MO, Chi MM, Cui Y, Pingsterhaus JM, McKnight RA, Mueckler M, Devaskar SU, Moley KH. GLUT8 is a glucose transporter responsible for insulin-stimulated glucose uptake in the blastocyst. Proc Natl Acad Sci USA 97: 7313-7318, 2000.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 7313-7318
-
-
Carayannopoulos, M.O.1
Chi, M.M.2
Cui, Y.3
Pingsterhaus, J.M.4
McKnight, R.A.5
Mueckler, M.6
Devaskar, S.U.7
Moley, K.H.8
-
8
-
-
2942580733
-
Covalent activation of heart AMP-activated protein kinase in response to physiological concentrations of long-chain fatty acids
-
Clark H, Carling D, Saggerson D. Covalent activation of heart AMP-activated protein kinase in response to physiological concentrations of long-chain fatty acids. Eur J Biochem 271: 2215-2224, 2004.
-
(2004)
Eur J Biochem
, vol.271
, pp. 2215-2224
-
-
Clark, H.1
Carling, D.2
Saggerson, D.3
-
9
-
-
45549102437
-
Oleate reverses palmitate-induced insulin resistance and inflammation in skeletal muscle cells
-
Coll T, Eyre E, Rodríguez-Calvo R, Palomer X, Sánchez RM, Merlos M, Laguna JC, Vázquez-Carrera M. Oleate reverses palmitate-induced insulin resistance and inflammation in skeletal muscle cells. J Biol Chem 283: 11107-11116, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 11107-11116
-
-
Coll, T.1
Eyre, E.2
Rodríguez-Calvo, R.3
Palomer, X.4
Sánchez, R.M.5
Merlos, M.6
Laguna, J.C.7
Vázquez-Carrera, M.8
-
10
-
-
78651247523
-
Peroxisome proliferator-activated receptor pj/8 agonism protects the kidney against ischemia/reperfusion injury in diabetic rats
-
Collino M, Benetti E, Miglio G, Castiglia S, Rosa AC, Aragno M, Thiemermann C, Fantozzi R. Peroxisome proliferator-activated receptor pj/8 agonism protects the kidney against ischemia/reperfusion injury in diabetic rats. Free Radic Biol Med 50: 345-353, 2011.
-
(2011)
Free Radic Biol Med
, vol.50
, pp. 345-353
-
-
Collino, M.1
Benetti, E.2
Miglio, G.3
Castiglia, S.4
Rosa, A.C.5
Aragno, M.6
Thiemermann, C.7
Fantozzi, R.8
-
11
-
-
33750572410
-
Differential effects of palmitate and palmitoleate on insulin action and glucose utilization in rat L6 skeletal muscle cells
-
Dimopoulos N, Watson M, Sakamoto K, Hundal HS. Differential effects of palmitate and palmitoleate on insulin action and glucose utilization in rat L6 skeletal muscle cells. Biochem J 399: 474-481, 2006.
-
(2006)
Biochem J
, vol.399
, pp. 474-481
-
-
Dimopoulos, N.1
Watson, M.2
Sakamoto, K.3
Hundal, H.S.4
-
12
-
-
0035462571
-
Glucose and palmitic acid induce degeneration of myofibrils and modulate apoptosis in rat adult cardiomyocytes
-
Dyntar D, Eppenberger-Eberhardt M, Maedler K, Pruschy M, Ep-penberger HM, Spinas GA, Donath MY. Glucose and palmitic acid induce degeneration of myofibrils and modulate apoptosis in rat adult cardiomyocytes. Diabetes 50: 2105-2113, 2001.
-
(2001)
Diabetes
, vol.50
, pp. 2105-2113
-
-
Dyntar, D.1
Eppenberger-Eberhardt, M.2
Maedler, K.3
Pruschy, M.4
Ep-Penberger, H.M.5
Spinas, G.A.6
Donath, M.Y.7
-
13
-
-
77950543816
-
Diacylglycerol-mediated insulin resistance
-
Erion DM, Shulman GI. Diacylglycerol-mediated insulin resistance. Nat Med 16: 400-402, 2010.
-
(2010)
Nat Med
, vol.16
, pp. 400-402
-
-
Erion, D.M.1
Shulman, G.I.2
-
14
-
-
0026040552
-
Highly insulin-responsive isolated rat heart muscle cells yielded by a modified isolation method
-
Fischer Y, Rose H, Kammermeier H. Highly insulin-responsive isolated rat heart muscle cells yielded by a modified isolation method. Life Sci 49: 1679-1688, 1991.
-
(1991)
Life Sci
, vol.49
, pp. 1679-1688
-
-
Fischer, Y.1
Rose, H.2
Kammermeier, H.3
-
15
-
-
33644823811
-
Leukaemia inhibitory factor stimulates glucose transport in isolated cardiomyocytes and induces insulin resistance after chronic exposure
-
Florholmen G, Thoresen G, Rustan A, Jensen J, Christensen G, Aas V. Leukaemia inhibitory factor stimulates glucose transport in isolated cardiomyocytes and induces insulin resistance after chronic exposure. Diabetologia 49: 724-731, 2006.
-
(2006)
Diabetologia
, vol.49
, pp. 724-731
-
-
Florholmen, G.1
Thoresen, G.2
Rustan, A.3
Jensen, J.4
Christensen, G.5
Aas, V.6
-
16
-
-
79961075137
-
Inhibition of the mTOR/p70S6K pathway is not involved in the insulin-sensitizing effect of AMPK on cardiac glucose uptake
-
Ginion A, Auquier J, Benton CR, Mouton C, Vanoverschelde JL, Hue L, Horman S, Beauloye C, Bertrand L. Inhibition of the mTOR/p70S6K pathway is not involved in the insulin-sensitizing effect of AMPK on cardiac glucose uptake. Am J Physiol Heart Circ Physiol 301: H469-H477, 2011.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.301
-
-
Ginion, A.1
Auquier, J.2
Benton, C.R.3
Mouton, C.4
Vanoverschelde, J.L.5
Hue, L.6
Horman, S.7
Beauloye, C.8
Bertrand, L.9
-
17
-
-
33646396190
-
Perfused hearts from Type 2 diabetic (db/db) mice show metabolic responsiveness to insulin
-
Hafstad AD, Solevåg GH, Severson DL, Larsen TS, Aasum E. Perfused hearts from Type 2 diabetic (db/db) mice show metabolic responsiveness to insulin. Am J Physiol Heart Circ Physiol 290: H1763-H1769, 2006.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.290
-
-
Hafstad, A.D.1
Solevåg, G.H.2
Severson, D.L.3
Larsen, T.S.4
Aasum, E.5
-
18
-
-
42649127400
-
IRS1-independent defects define major nodes of insulin resistance
-
Hoehn KL, Hohnen-Behrens C, Cederberg A, Wu LE, Turner N, Yuasa T, Ebina Y, James DE. IRS1-independent defects define major nodes of insulin resistance. Cell Metab 7: 421-433, 2008.
-
(2008)
Cell Metab
, vol.7
, pp. 421-433
-
-
Hoehn, K.L.1
Hohnen-Behrens, C.2
Cederberg, A.3
Wu, L.E.4
Turner, N.5
Yuasa, T.6
Ebina, Y.7
James, D.E.8
-
19
-
-
33847026801
-
Ceramide- and oxidant-induced insulin resistance involve loss of insulin-dependent Rac-activation and actin remodeling in muscle cells
-
JeBailey L, Wanono O, Niu W, Roessler J, Rudich A, Klip A. Ceramide- and oxidant-induced insulin resistance involve loss of insulin-dependent Rac-activation and actin remodeling in muscle cells. Diabetes 56: 394-403, 2007.
-
(2007)
Diabetes
, vol.56
, pp. 394-403
-
-
Jebailey, L.1
Wanono, O.2
Niu, W.3
Roessler, J.4
Rudich, A.5
Klip, A.6
-
20
-
-
0027189905
-
The functional recovery of post-ischemic myocardium requires glycolysis during early reperfusion
-
Jeremy RW, Ambrosio G, Pike MM, Jacobus WE, Becker LC. The functional recovery of post-ischemic myocardium requires glycolysis during early reperfusion. J Mol Cell Cardiol 25: 261-276, 1993.
-
(1993)
J Mol Cell Cardiol
, vol.25
, pp. 261-276
-
-
Jeremy, R.W.1
Ambrosio, G.2
Pike, M.M.3
Jacobus, W.E.4
Becker, L.C.5
-
21
-
-
0026587014
-
Relation between glycolysis and calcium homeostasis in postischemic myocardium
-
Jeremy RW, Koretsune Y, Marban E, Becker LC. Relation between glycolysis and calcium homeostasis in postischemic myocardium. Circ Res 70: 1180-1190, 1992.
-
(1992)
Circ Res
, vol.70
, pp. 1180-1190
-
-
Jeremy, R.W.1
Koretsune, Y.2
Marban, E.3
Becker, L.C.4
-
22
-
-
29344471474
-
Palmitate induces tumor necrosis factor-alpha expression in C2C12 skeletal muscle cells by a mechanism involving protein kinase C and nuclear factor-kappaB activation
-
Jové M, Planavila A, Sánchez RM, Merlos M, Laguna JC, Vázquez-Carrera M. Palmitate induces tumor necrosis factor-alpha expression in C2C12 skeletal muscle cells by a mechanism involving protein kinase C and nuclear factor-kappaB activation. Endocrinology 147: 552-561, 2006.
-
(2006)
Endocrinology
, vol.147
, pp. 552-561
-
-
Jové, M.1
Planavila, A.2
Sánchez, R.M.3
Merlos, M.4
Laguna, J.C.5
Vázquez-Carrera, M.6
-
23
-
-
0037151026
-
A method to identify serine kinase substrates.Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain
-
Kane S, Sano H, Liu SC, Asara JM, Lane WS, Garner CC, Lienhard GE. A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain. J Biol Chem 277: 22115-22118, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 22115-22118
-
-
Kane, S.1
Sano, H.2
Liu, S.C.3
Asara, J.M.4
Lane, W.S.5
Garner, C.C.6
Lienhard, G.E.7
-
25
-
-
37449020075
-
Muoio DM.Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
-
Koves TR, Ussher JR, Noland RC, Slentz D, Mosedale M, Ilkayeva O, Bain J, Stevens R, Dyck JR, Newgard CB, Lopaschuk GD, Muoio DM.Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance. Cell Metab 7: 45-56, 2008.
-
(2008)
Cell Metab
, vol.7
, pp. 45-56
-
-
Koves, T.R.1
Ussher, J.R.2
Noland, R.C.3
Slentz, D.4
Mosedale, M.5
Ilkayeva, O.6
Bain, J.7
Stevens, R.8
Dyck, J.R.9
Newgard, C.B.10
Lopaschuk, G.D.11
-
26
-
-
33747039008
-
Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle
-
Kramer HF, Witczak CA, Fujii N, Jessen N, Taylor EB, Arnolds DE, Sakamoto K, Hirshman MF, Goodyear LJ. Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle. Diabetes 55: 2067-2076, 2006.
-
(2006)
Diabetes
, vol.55
, pp. 2067-2076
-
-
Kramer, H.F.1
Witczak, C.A.2
Fujii, N.3
Jessen, N.4
Taylor, E.B.5
Arnolds, D.E.6
Sakamoto, K.7
Hirshman, M.F.8
Goodyear, L.J.9
-
27
-
-
0034717680
-
Phosphorylation of connexin43 on serine368 by protein kinase C regulates gap junctional communication
-
Lampe PD, TenBroek EM, Burt JM, Kurata WE, Johnson RG, Lau AF. Phosphorylation of connexin43 on serine368 by protein kinase C regulates gap junctional communication. J Cell Biol 149: 1503-1512, 2000.
-
(2000)
J Cell Biol
, vol.149
, pp. 1503-1512
-
-
Lampe, P.D.1
Tenbroek, E.M.2
Burt, J.M.3
Kurata, W.E.4
Johnson, R.G.5
Lau, A.F.6
-
28
-
-
27844528870
-
Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking
-
Larance M, Ramm G, Stöckli J, van Dam EM, Winata S, Wasinger V, Simpson F, Graham M, Junutula JR, Guilhaus M, James DE. Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking. J Biol Chem 280: 37803-37813, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 37803-37813
-
-
Larance, M.1
Ramm, G.2
Stöckli, J.3
van Dam, E.M.4
Winata, S.5
Wasinger, V.6
Simpson, F.7
Graham, M.8
Junutula, J.R.9
Guilhaus, M.10
James, D.E.11
-
29
-
-
37249093922
-
SOCS proteins causing trouble in insulin action
-
Lebrun P, Van Obberghen E. SOCS proteins causing trouble in insulin action. Acta Physiol (Oxf) 192: 29-36, 2008.
-
(2008)
Acta Physiol (Oxf)
, vol.192
, pp. 29-36
-
-
Lebrun, P.1
van Obberghen, E.2
-
30
-
-
18444412555
-
Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662
-
Leesnitzer LM, Parks DJ, Bledsoe RK, Cobb JE, Collins JL, Consler TG, Davis RG, Hull-Ryde EA, Lenhard JM, Patel L, Plunket KD, Shenk JL, Stimmel JB, Therapontos C, Willson TM, Blanchard SG.Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662. Biochemistry 41: 6640-6650, 2002.
-
(2002)
Biochemistry
, vol.41
, pp. 6640-6650
-
-
Leesnitzer, L.M.1
Parks, D.J.2
Bledsoe, R.K.3
Cobb, J.E.4
Collins, J.L.5
Consler, T.G.6
Davis, R.G.7
Hull-Ryde, E.A.8
Lenhard, J.M.9
Patel, L.10
Plunket, K.D.11
Shenk, J.L.12
Stimmel, J.B.13
Therapontos, C.14
Willson, T.M.15
Blanchard, S.G.16
-
31
-
-
70349760843
-
The molecular basis of insulin-stimulated glucose uptake: Signalling, trafficking and potential drug targets
-
Leney SE, Tavaré JM. The molecular basis of insulin-stimulated glucose uptake: signalling, trafficking and potential drug targets. J Endocrinol 203: 1-18, 2009.
-
(2009)
J Endocrinol
, vol.203
, pp. 1-18
-
-
Leney, S.E.1
Tavaré, J.M.2
-
32
-
-
0037453056
-
Triglyceride accumulation protects against fatty acid-induced lipotoxicity
-
Listenberger LL, Han X, Lewis SE, Cases S, Farese RV, Ory DS, Schaffer JE. Triglyceride accumulation protects against fatty acid-induced lipotoxicity. Proc Natl Acad Sci USA 100: 3077-3082, 2003.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 3077-3082
-
-
Listenberger, L.L.1
Han, X.2
Lewis, S.E.3
Cases, S.4
Farese, R.V.5
Ory, D.S.6
Schaffer, J.E.7
-
34
-
-
50949093056
-
Bioinformatic profiling of the transcrip-tional response of adult rat cardiomyocytes to distinct fatty acids
-
Lockridge JB, Sailors ML, Durgan DJ, Egbejimi O, Jeong WJ, Bray MS, Stanley WC, Young ME. Bioinformatic profiling of the transcrip-tional response of adult rat cardiomyocytes to distinct fatty acids. J Lipid Res 49: 1395-1408, 2008.
-
(2008)
J Lipid Res
, vol.49
, pp. 1395-1408
-
-
Lockridge, J.B.1
Sailors, M.L.2
Durgan, D.J.3
Egbejimi, O.4
Jeong, W.J.5
Bray, M.S.6
Stanley, W.C.7
Young, M.E.8
-
35
-
-
0028522881
-
The 1993 Merck Frosst Award.Acetyl-CoA carboxylase: An important regulator of fatty acid oxidation in the heart
-
Lopaschuk GD, Gamble J. The 1993 Merck Frosst Award. Acetyl-CoA carboxylase: an important regulator of fatty acid oxidation in the heart. Can J Physiol Pharmacol 72: 1101-1109, 1994.
-
(1994)
Can J Physiol Pharmacol
, vol.72
, pp. 1101-1109
-
-
Lopaschuk, G.D.1
Gamble, J.2
-
36
-
-
24344486460
-
Oleate prevents palmitate-induced cyto-toxic stress in cardiac myocytes
-
Miller TA, LeBrasseur NK, Cote GM, Trucillo MP, Pimentel DR, Ido Y, Ruderman NB, Sawyer DB. Oleate prevents palmitate-induced cyto-toxic stress in cardiac myocytes. Biochem Biophys Res Commun 336: 309-315, 2005.
-
(2005)
Biochem Biophys Res Commun
, vol.336
, pp. 309-315
-
-
Miller, T.A.1
Lebrasseur, N.K.2
Cote, G.M.3
Trucillo, M.P.4
Pimentel, D.R.5
Ido, Y.6
Ruderman, N.B.7
Sawyer, D.B.8
-
37
-
-
0029075192
-
Serine palmitoyltransferase is the primary target of a sphingosine-like immuno-suppressant, ISP-1/myriocin
-
Miyake Y, Kozutsumi Y, Nakamura S, Fujita T, Kawasaki T. Serine palmitoyltransferase is the primary target of a sphingosine-like immuno-suppressant, ISP-1/myriocin. Biochem Biophys Res Commun 211: 396-403, 1995.
-
(1995)
Biochem Biophys Res Commun
, vol.211
, pp. 396-403
-
-
Miyake, Y.1
Kozutsumi, Y.2
Nakamura, S.3
Fujita, T.4
Kawasaki, T.5
-
38
-
-
33644639794
-
Retinoic acids increase expression of GLUT4 in dedifferentiated and hypertrophied cardiac myocytes
-
Montessuit C, Papageorgiou I, Campos L, Lerch R. Retinoic acids increase expression of GLUT4 in dedifferentiated and hypertrophied cardiac myocytes. Basic Res Cardiol 101: 27-35, 2006.
-
(2006)
Basic Res Cardiol
, vol.101
, pp. 27-35
-
-
Montessuit, C.1
Papageorgiou, I.2
Campos, L.3
Lerch, R.4
-
39
-
-
40849131138
-
Nuclear receptor agonists improve insulin responsiveness in cultured cardiomyocytes through enhanced signaling and preserved cytoskeletal architecture
-
Montessuit C, Papageorgiou I, Lerch R. Nuclear receptor agonists improve insulin responsiveness in cultured cardiomyocytes through enhanced signaling and preserved cytoskeletal architecture. Endocrinology 149: 1064-1074, 2008.
-
(2008)
Endocrinology
, vol.149
, pp. 1064-1074
-
-
Montessuit, C.1
Papageorgiou, I.2
Lerch, R.3
-
40
-
-
41449087811
-
Rapid activation of Akt2 is sufficient to stimulate GLUT4 translocation in 3T3-L1 adipocytes
-
Ng Y, Ramm G, Lopez JA, James DE. Rapid activation of Akt2 is sufficient to stimulate GLUT4 translocation in 3T3-L1 adipocytes. Cell Metab 7: 348-356, 2008.
-
(2008)
Cell Metab
, vol.7
, pp. 348-356
-
-
Ng, Y.1
Ramm, G.2
Lopez, J.A.3
James, D.E.4
-
41
-
-
34547911466
-
Abnormal function and glucose metabolism in the type-2 diabetic db/db mouse heart
-
Panagia M, Schneider JE, Brown B, Cole MA, Clarke K. Abnormal function and glucose metabolism in the type-2 diabetic db/db mouse heart. Can J Physiol Pharmacol 85: 289-294, 2007.
-
(2007)
Can J Physiol Pharmacol
, vol.85
, pp. 289-294
-
-
Panagia, M.1
Schneider, J.E.2
Brown, B.3
Cole, M.A.4
Clarke, K.5
-
42
-
-
54249093047
-
Ceramide is a cardio-toxin in lipotoxic cardiomyopathy
-
Park TS, Hu Y, Noh HL, Drosatos K, Okajima K, Buchanan J, Tuinei J, Homma S, Jiang XC, Abel ED, Goldberg IJ. Ceramide is a cardio-toxin in lipotoxic cardiomyopathy. J Lipid Res 49: 2101-2112, 2008.
-
(2008)
J Lipid Res
, vol.49
, pp. 2101-2112
-
-
Park, T.S.1
Hu, Y.2
Noh, H.L.3
Drosatos, K.4
Okajima, K.5
Buchanan, J.6
Tuinei, J.7
Homma, S.8
Jiang, X.C.9
Abel, E.D.10
Goldberg, I.J.11
-
43
-
-
35448997780
-
Inactivation of peroxisome proliferator-activated receptor isoforms alpha, beta/delta, and gamma mediate distinct facets of hypertrophic transformation of adult cardiac myocytes
-
Pellieux C, Montessuit C, Papageorgiou I, Lerch R. Inactivation of peroxisome proliferator-activated receptor isoforms alpha, beta/delta, and gamma mediate distinct facets of hypertrophic transformation of adult cardiac myocytes. Pflugers Arch 455: 443-454, 2007.
-
(2007)
Pflugers Arch
, vol.455
, pp. 443-454
-
-
Pellieux, C.1
Montessuit, C.2
Papageorgiou, I.3
Lerch, R.4
-
44
-
-
34250303939
-
Key role for ceramides in mediating insulin resistance in human muscle cells
-
Pickersgill L, Litherland GJ, Greenberg AS, Walker M, Yeaman SJ. Key role for ceramides in mediating insulin resistance in human muscle cells. J Biol Chem 282: 12583-12589, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 12583-12589
-
-
Pickersgill, L.1
Litherland, G.J.2
Greenberg, A.S.3
Walker, M.4
Yeaman, S.J.5
-
45
-
-
4544242908
-
Intracellular ceramide synthesis and protein kinase Czeta activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells
-
Powell DJ, Turban S, Gray A, Hajduch E, Hundal HS. Intracellular ceramide synthesis and protein kinase Czeta activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells. Biochem J 382: 619-629, 2004.
-
(2004)
Biochem J
, vol.382
, pp. 619-629
-
-
Powell, D.J.1
Turban, S.2
Gray, A.3
Hajduch, E.4
Hundal, H.S.5
-
46
-
-
33847646640
-
Carnitine revisited: Potential use as adjunctive treatment in diabetes
-
Power R, Hulver M, Zhang J, Dubois J, Marchand R, Ilkayeva O, Muoio D, Mynatt R. Carnitine revisited: potential use as adjunctive treatment in diabetes. Diabetologia 50: 824-832, 2007.
-
(2007)
Diabetologia
, vol.50
, pp. 824-832
-
-
Power, R.1
Hulver, M.2
Zhang, J.3
Dubois, J.4
Marchand, R.5
Ilkayeva, O.6
Muoio, D.7
Mynatt, R.8
-
47
-
-
4143070653
-
What's in a picture?The temptation of image manipulation
-
Rossner M, Yamada KM. What's in a picture? The temptation of image manipulation. J Cell Biol 166: 11-15, 2004.
-
(2004)
J Cell Biol
, vol.166
, pp. 11-15
-
-
Rossner, M.1
Yamada, K.M.2
-
48
-
-
0037677096
-
Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation
-
Sano H, Kane S, Sano E, Mîinea CP, Asara JM, Lane WS, Garner CW, Lienhard GE. Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation. J Biol Chem 278: 14599-14602, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 14599-14602
-
-
Sano, H.1
Kane, S.2
Sano, E.3
Mîinea, C.P.4
Asara, J.M.5
Lane, W.S.6
Garner, C.W.7
Lienhard, G.E.8
-
49
-
-
0036333737
-
Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B
-
Scheid MP, Marignani PA, Woodgett JR. Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B. Mol Cell Biol 22: 6247-6260, 2002.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 6247-6260
-
-
Scheid, M.P.1
Marignani, P.A.2
Woodgett, J.R.3
-
51
-
-
0037853260
-
Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepa-tocytes
-
Senn JJ, Klover PJ, Nowak IA, Zimmers TA, Koniaris LG, Furlanetto RW, Mooney RA. Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepa-tocytes. J Biol Chem 278: 13740-13746, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 13740-13746
-
-
Senn, J.J.1
Klover, P.J.2
Nowak, I.A.3
Zimmers, T.A.4
Koniaris, L.G.5
Furlanetto, R.W.6
Mooney, R.A.7
-
52
-
-
4744344777
-
Fatty acid-induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of nuclear factor kappa B
-
Sinha S, Perdomo G, Brown NF, O'Doherty RM. Fatty acid-induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of nuclear factor kappa B. J Biol Chem 279: 41294-41301, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 41294-41301
-
-
Sinha, S.1
Perdomo, G.2
Brown, N.F.3
O'Doherty, R.M.4
-
53
-
-
0021904439
-
Substrate utilization of adult cardiac myocytes
-
Spahr R, Probst I, Piper HM. Substrate utilization of adult cardiac myocytes. Basic Res Cardiol 1: 53-56, 1985.
-
(1985)
Basic Res Cardiol
, vol.1
, pp. 53-56
-
-
Spahr, R.1
Probst, I.2
Piper, H.M.3
-
54
-
-
33847062845
-
The Rab GTPase-activating protein AS160 integrates Akt, protein kinase C, and AMP-activated protein kinase signals regulating GLUT4 traffic
-
Thong FS, Bilan PJ, Klip A. The Rab GTPase-activating protein AS160 integrates Akt, protein kinase C, and AMP-activated protein kinase signals regulating GLUT4 traffic. Diabetes 56: 414-423, 2007.
-
(2007)
Diabetes
, vol.56
, pp. 414-423
-
-
Thong, F.S.1
Bilan, P.J.2
Klip, A.3
-
55
-
-
0035912954
-
Responses of GLUT4-deficient hearts to ischemia underscore the importance of glycolysis
-
Tian R, Abel ED. Responses of GLUT4-deficient hearts to ischemia underscore the importance of glycolysis. Circulation 103: 2961-2966, 2001.
-
(2001)
Circulation
, vol.103
, pp. 2961-2966
-
-
Tian, R.1
Abel, E.D.2
-
56
-
-
59049100254
-
Protein kinase C theta (PKCtheta)-dependent phosphorylation of PDK1 at Ser504 and Ser532 contributes to palmitate-induced insulin resistance
-
Wang C, Liu M, Riojas RA, Xin X, Gao Z, Zeng R, Wu J, Dong LQ, Liu F. Protein kinase C theta (PKCtheta)-dependent phosphorylation of PDK1 at Ser504 and Ser532 contributes to palmitate-induced insulin resistance. J Biol Chem 284: 2038-2044, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 2038-2044
-
-
Wang, C.1
Liu, M.2
Riojas, R.A.3
Xin, X.4
Gao, Z.5
Zeng, R.6
Wu, J.7
Dong, L.Q.8
Liu, F.9
-
57
-
-
59849098608
-
Modulating serine palmitoyl transferase (SPT) expression and activity unveils a crucial role in lipid-induced insulin resistance in rat skeletal muscle cells
-
Watson ML, Coghlan M, Hundal HS. Modulating serine palmitoyl transferase (SPT) expression and activity unveils a crucial role in lipid-induced insulin resistance in rat skeletal muscle cells. Biochem J 417: 791-801, 2009.
-
(2009)
Biochem J
, vol.417
, pp. 791-801
-
-
Watson, M.L.1
Coghlan, M.2
Hundal, H.S.3
-
58
-
-
0023834406
-
A cascade of tyrosine autophosphorylation in the (3-subunit activates the phosphotransferase of the insulin receptor
-
White M, Shoelson S, Keutmann H, Kahn C. A cascade of tyrosine autophosphorylation in the (3-subunit activates the phosphotransferase of the insulin receptor. J Biol Chem 263: 2969-2980, 1988.
-
(1988)
J Biol Chem
, vol.263
, pp. 2969-2980
-
-
White, M.1
Shoelson, S.2
Keutmann, H.3
Kahn, C.4
-
59
-
-
14244268695
-
Insulin and contraction stimulate exocytosis, but increased AMP-activated protein kinase activity resulting from oxidative metabolism stress slows endocytosis of GLUT4 in cardiomyocytes
-
Yang J, Holman GD. Insulin and contraction stimulate exocytosis, but increased AMP-activated protein kinase activity resulting from oxidative metabolism stress slows endocytosis of GLUT4 in cardiomyocytes. J Biol Chem 280: 4070-4078, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 4070-4078
-
-
Yang, J.1
Holman, G.D.2
-
60
-
-
78650481257
-
Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation
-
Zhang L, Ussher JR, Oka T, Cadete VJ, Wagg C, Lopaschuk GD. Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation. Cardiovasc Res 89: 148-156, 2010.
-
(2010)
Cardiovasc Res
, vol.89
, pp. 148-156
-
-
Zhang, L.1
Ussher, J.R.2
Oka, T.3
Cadete, V.J.4
Wagg, C.5
Lopaschuk, G.D.6
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