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Volumn 5, Issue 2, 2012, Pages 72-76

Expression profiles in stage II colon cancer according to APC gene status

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN;

EID: 84859447064     PISSN: None     EISSN: 19365233     Source Type: Journal    
DOI: 10.1593/tlo.11325     Document Type: Article
Times cited : (17)

References (25)
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    • Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations
    • Segditsas S, Sieber OM, Rowan A, Setien F, Neale K, Phillips RK, Ward R, Esteller M, and Tomlinson IP (2008). Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations. Exp Mol Pathol 85, 201-206.
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    • Segditsas, S.1    Sieber, O.M.2    Rowan, A.3    Setien, F.4    Neale, K.5    Phillips, R.K.6    Ward, R.7    Esteller, M.8    Tomlinson, I.P.9
  • 7
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    • The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: A new facet to Knudson's "two-hit" hypothesis
    • Lamlum H, Ilyas M, Rowan A, Clark S, Johnson V, Bell J, Frayling I, Efstathiou J, Pack K, Payne S, et al. (1999). The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's "two-hit" hypothesis. Nat Med 5, 1071-1075.
    • (1999) Nat Med , vol.5 , pp. 1071-1075
    • Lamlum, H.1    Ilyas, M.2    Rowan, A.3    Clark, S.4    Johnson, V.5    Bell, J.6    Frayling, I.7    Efstathiou, J.8    Pack, K.9    Payne, S.10
  • 10
    • 0037699438 scopus 로고    scopus 로고
    • Refining the relation between "first hits" and "second hits" at the APC locus: The "loose fit" model and evidence for differences in somatic mutation spectra among patients
    • Crabtree M, Sieber OM, Lipton L, Hodgson SV, Lamlum H, Thomas HJ, Neale K, Phillips RK, Heinimann K, and Tomlinson IP (2003). Refining the relation between "first hits" and "second hits" at the APC locus: the "loose fit" model and evidence for differences in somatic mutation spectra among patients. Oncogene 22, 4257-4265.
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  • 11
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    • The "just-right" signaling model: APC somatic mutations are selected based on a specific level of activation of the β-catenin signaling cascade
    • Albuquerque C, Breukel C, van der Luijt R, Fidalgo P, Lage P, Slors FJ, Leitão CN, Fodde R, and Smits R (2002). The "just-right" signaling model: APC somatic mutations are selected based on a specific level of activation of the β-catenin signaling cascade. Hum Mol Genet 11, 1549-1560.
    • (2002) Hum Mol Genet , vol.11 , pp. 1549-1560
    • Albuquerque, C.1    Breukel, C.2    van der Luijt, R.3    Fidalgo, P.4    Lage, P.5    Slors, F.J.6    Leitão, C.N.7    Fodde, R.8    Smits, R.9
  • 14
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    • Disease severity and genetic pathways in attenuated familial adenomatous polyposis vary greatly but depend on the site of the germline mutation
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    • (2006) Gut , vol.55 , pp. 1440-1448
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    • Article 3
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.