Disease severity and genetic pathways in attenuated familial adenomatous polyposis vary greatly but depend on the site of the germline mutation

Gut

Volumn 55, Issue 10, 2006, Pages 1440-1448

  Sieber, O M ^a   Segditsas, S ^a   Knudsen, A L ^b   Zhang, J ^c   Luz, J ^c   Rowan, A J ^a   Spain, S L ^a   Thirlwell, C ^a   Howarth, K M ^a   Jaeger, E E M ^a   Robinson, J ^a   Volikos, E ^a   Silver, A ^a   Kelly, G ^a   Aretz, S ^d   Frayling, I ^e   Hutter, P ^f   Dunlop, M ^g   Guenther, T ^a   Neale, K ^h   Phillips, R ^h   Heinimann, K ^c   Tomlinson, Ian P M ^a   more..

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b HVIDOVRE HOSPITAL   (Denmark)

^c UNIVERSITY OF BASEL   (Switzerland)

^d UNIVERSITY OF BONN   (Germany)

^e UNIVERSITY HOSPITAL OF WALES   (United Kingdom)

^f Institut Central des Hopitaux Valaisans   (Switzerland)

^g WESTERN GENERAL HOSPITAL   (United Kingdom)

^h ST MARK S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOMATOUS POLYP; ADULT; AGED; ALLELE; ARTICLE; CARCINOGENESIS; CLINICAL ARTICLE; COLORECTAL TUMOR; CONTROLLED STUDY; DISEASE SEVERITY; FAMILIAL DISEASE; FEMALE; GENE MUTATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MALE; PHENOTYPE; PRIORITY JOURNAL; SOMATIC MUTATION; WILD TYPE;

ADENOMATOUS POLYPOSIS COLI; ADENOMATOUS POLYPOSIS COLI PROTEIN; ADULT; AGED; DNA MUTATIONAL ANALYSIS; EXONS; FEMALE; GERM-LINE MUTATION; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MIDDLE AGED; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 33749185580     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.2005.087106     Document Type: Article

References (19)

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