Statins Prevent Bisphosphonate-Induced γ,δ-T-Cell Proliferation and Activation in Vitro

Journal of Bone and Mineral Research

Volumn 19, Issue 2, 2004, Pages 278-288

  Thompson, Keith ^a   Rogers, Michael J ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Acute phase response; Farnesyl diphosphate synthase; Mevalonate; Osteoclast; Osteoporosis

Indexed keywords

ALENDRONIC ACID; ALLYL COMPOUND; BISPHOSPHONIC ACID DERIVATIVE; BROMOHYDRIN PYROPHOSPHATE; CD3 ANTIGEN; CLODRONIC ACID; COMPACTIN; DESOXOLOVASTATIN; DIMETHYLALLYL DIPHOSPHATE; GAMMA INTERFERON; GERANYLTRANSFERASE; GGTI 298; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IBANDRONIC ACID; INTERLEUKIN 2; ISOPENTENYL DIPHOSPHATE; MEVALONIC ACID; MEVINOLIN; N [[5 [(2 AMINO 3 MERCAPTOPROPYL)AMINO][1,1' BIPHENYL] 2 YL]CARBONYL]METHIONINE METHYL ESTER; NE 10571; NE 10790; NE 11808; NE 11809; NE 21650; PAMIDRONIC ACID; SQUALENE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ZARAGOZIC ACID; ZOLEDRONIC ACID;

ACUTE PHASE RESPONSE; ARTICLE; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DRUG INDUCED DISEASE; ENZYME INHIBITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTE PROLIFERATION; METABOLIC BONE DISEASE; OSTEOCLAST; OSTEOLYSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN PROCESSING; T LYMPHOCYTE ACTIVATION;

ALKYL AND ARYL TRANSFERASES; CELL DIVISION; DIPHOSPHONATES; GERANYLTRANSTRANSFERASE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LYMPHOCYTE ACTIVATION; MEVALONIC ACID; PROTEIN ISOPRENYLATION; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTES;

EID: 1642526540     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/JBMR.0301230     Document Type: Article

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