-
1
-
-
0142229704
-
Intracellular and extracellular roles of S100 proteins
-
Donato, R. ( 2003) Intracellular and extracellular roles of S100 proteins. Microsc. Res. Tech. 60, 540-551.
-
(2003)
Microsc. Res. Tech.
, vol.60
, pp. 540-551
-
-
Donato, R.1
-
2
-
-
0026598767
-
Increased S100 beta neurotrophic activity in Alzheimer's disease temporal lobe
-
Marshak, D. R., Pesce, S. A., Stanley, L. C., Griffin, W. S. ( 1992) Increased S100 beta neurotrophic activity in Alzheimer's disease temporal lobe. Neurobiol. Aging 13, 1-7.
-
(1992)
Neurobiol. Aging
, vol.13
, pp. 1-7
-
-
Marshak, D.R.1
Pesce, S.A.2
Stanley, L.C.3
Griffin, W.S.4
-
3
-
-
80052501210
-
Resolving controversies on the path to Alzheimer's therapeutics
-
Selkoe, D. J. ( 2011) Resolving controversies on the path to Alzheimer's therapeutics. Nat. Med. 17, 1060-1065.
-
(2011)
Nat. Med.
, vol.17
, pp. 1060-1065
-
-
Selkoe, D.J.1
-
4
-
-
0037315878
-
A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease
-
Lahiri, D. K., Farlow, M. R., Sambamurti, K., Greig, N. H., Giacobini, E., Schneider, L. S. ( 2003) A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease. Curr. Drug Targets 4, 97-112
-
(2003)
Curr. Drug Targets
, vol.4
, pp. 97-112
-
-
Lahiri, D.K.1
Farlow, M.R.2
Sambamurti, K.3
Greig, N.H.4
Giacobini, E.5
Schneider, L.S.6
-
5
-
-
0842269766
-
Anti-Abeta: the good, the bad, and the unforeseen
-
Broytman, O. and Malter, J. S. ( 2004) Anti-Abeta: the good, the bad, and the unforeseen. J. Neurosci. Res. 75, 301-306.
-
(2004)
J. Neurosci. Res.
, vol.75
, pp. 301-306
-
-
Broytman, O.1
Malter, J.S.2
-
6
-
-
3042649475
-
Retinoic acid-mediated phospholipase A2 signaling in the nucleus
-
Farooqui, A. A., Antony, P., Ong, W. Y., Horrocks, L. A., and Freysz, L. ( 2004) Retinoic acid-mediated phospholipase A2 signaling in the nucleus. Brain Res. Brain Res. Rev. 45, 179-195.
-
(2004)
Brain Res. Brain Res. Rev.
, vol.45
, pp. 179-195
-
-
Farooqui, A.A.1
Antony, P.2
Ong, W.Y.3
Horrocks, L.A.4
Freysz, L.5
-
7
-
-
0037134408
-
All-trans-Retinoic acid increases nitric oxide synthesis by endothelial cells: a role for the induction of dimethylarginine dimethylaminohydrolase
-
Achan, V., Tran, C. T., Arrigoni, F., Whitley, G. S., Leiper, J. M., and Vallance, P. ( 2002) All-trans-Retinoic acid increases nitric oxide synthesis by endothelial cells: a role for the induction of dimethylarginine dimethylaminohydrolase. Circ. Res. 90, 764-769.
-
(2002)
Circ. Res.
, vol.90
, pp. 764-769
-
-
Achan, V.1
Tran, C.T.2
Arrigoni, F.3
Whitley, G.S.4
Leiper, J.M.5
Vallance, P.6
-
8
-
-
4344628460
-
Disruption of the retinoid signalling pathway causes a deposition of amyloid beta in the adult rat brain
-
Corcoran, J. P., So, P. L., and Maden, M. ( 2004) Disruption of the retinoid signalling pathway causes a deposition of amyloid beta in the adult rat brain. Eur. J. Neurosci. 20, 896-902.
-
(2004)
Eur. J. Neurosci.
, vol.20
, pp. 896-902
-
-
Corcoran, J.P.1
So, P.L.2
Maden, M.3
-
9
-
-
67349129934
-
Effects of marginal vitamin A deficiency and intervention on learning and memory in young rats
-
Mao, C. T., Li, T. Y., Liu, Y. X., and Qu, P. ( 2005) Effects of marginal vitamin A deficiency and intervention on learning and memory in young rats. Zhonghua Er Ke Za Zhi. 43, 526-530
-
(2005)
Zhonghua Er Ke Za Zhi.
, vol.43
, pp. 526-530
-
-
Mao, C.T.1
Li, T.Y.2
Liu, Y.X.3
Qu, P.4
-
10
-
-
41249099527
-
Retinoic acid as cause of cell proliferation or cell growth inhibition depending on activation of one of two different nuclear receptors
-
Wolf, G. ( 2008) Retinoic acid as cause of cell proliferation or cell growth inhibition depending on activation of one of two different nuclear receptors. Nutr. Rev. 66, 55-59.
-
(2008)
Nutr. Rev.
, vol.66
, pp. 55-59
-
-
Wolf, G.1
-
11
-
-
4544227975
-
Vitamin A exhibits potent antiamyloidogenic and fibril-destabilizing effects in vitro
-
Ono, K., Yoshiike, Y., Takashima, A., Hasegawa, K., Naiki, H., and Yamada, M. ( 2004) Vitamin A exhibits potent antiamyloidogenic and fibril-destabilizing effects in vitro. Exp. Neurol. 189, 380-392
-
(2004)
Exp. Neurol.
, vol.189
, pp. 380-392
-
-
Ono, K.1
Yoshiike, Y.2
Takashima, A.3
Hasegawa, K.4
Naiki, H.5
Yamada, M.6
-
12
-
-
81855199775
-
Vitamin A has anti-oligomerization effects on amyloid-β in vitro
-
Takasaki, J., Ono, K., Yoshiike, Y., Hirohata, M., Ikeda, T., Morinaga, A., Takashima, A., and Yamada, M. ( 2011) Vitamin A has anti-oligomerization effects on amyloid-β in vitro. J. Alzheimers Dis. 27, 271-280.
-
(2011)
J. Alzheimers Dis.
, vol.27
, pp. 271-280
-
-
Takasaki, J.1
Ono, K.2
Yoshiike, Y.3
Hirohata, M.4
Ikeda, T.5
Morinaga, A.6
Takashima, A.7
Yamada, M.8
-
13
-
-
0034986361
-
Oxidative stress induced-neurodegenerative diseases: the need for antioxidants that penetrate the blood brain barrier
-
Gilgun-Sherki, Y., Melamed, E., and Offen, D. ( 200) Oxidative stress induced-neurodegenerative diseases: the need for antioxidants that penetrate the blood brain barrier. Neuropharmacology 40, 959-975.
-
Neuropharmacology
, vol.40
, pp. 959-975
-
-
Gilgun-Sherki, Y.1
Melamed, E.2
Offen, D.3
-
14
-
-
67649359888
-
Up-regulation of the alpha-secretase ADAM10 by retinoic acid receptors and acitretin
-
Tippmann, F., Hundt, J., Schneider, A., Endres, K., Fahrenholz, F. ( 2009) Up-regulation of the alpha-secretase ADAM10 by retinoic acid receptors and acitretin. FASEB 23, 1643-1554.
-
(2009)
FASEB
, vol.23
, pp. 1643-1554
-
-
Tippmann, F.1
Hundt, J.2
Schneider, A.3
Endres, K.4
Fahrenholz, F.5
-
15
-
-
67650717654
-
Oral administration of synthetic retinoid Am80 (Tamibarotene) decreases brain beta-amyloid peptides in APP23 mice
-
Kawahara, K., Nishi, K., Suenobu, M., Ohtsuka, H., Maeda, A., Nagatomo, K., Kuniyasu, A., Staufenbiel, M., Nakagomi, M., Shudo, K., and Nakayama, H. ( 2009). Oral administration of synthetic retinoid Am80 (Tamibarotene) decreases brain beta-amyloid peptides in APP23 mice. Biol. Pharm. Bull. 32, 1307-1309.
-
(2009)
Biol. Pharm. Bull.
, vol.32
, pp. 1307-1309
-
-
Kawahara, K.1
Nishi, K.2
Suenobu, M.3
Ohtsuka, H.4
Maeda, A.5
Nagatomo, K.6
Kuniyasu, A.7
Staufenbiel, M.8
Nakagomi, M.9
Shudo, K.10
Nakayama, H.11
-
16
-
-
70849097441
-
All-trans retinoic acid as a novel therapeutic strategy for Alzheimer's disease
-
Lee, H.-P., Casadesus, G., Zhu, X., Lee, H.-G., Perry, G., Smith, M. A., Gustaw-Rothenberg, K., and Lerner, A. ( 2009) All-trans retinoic acid as a novel therapeutic strategy for Alzheimer's disease. Expert Rev. Neurotherapeut. 9, 1615-1621.
-
(2009)
Expert Rev. Neurotherapeut.
, vol.9
, pp. 1615-1621
-
-
Lee, H.-P.1
Casadesus, G.2
Zhu, X.3
Lee, H.-G.4
Perry, G.5
Smith, M.A.6
Gustaw-Rothenberg, K.7
Lerner, A.8
-
17
-
-
67149115541
-
Towards retinoid therapy for Alzheimer's disease
-
Shudo, K., Fukasawa, H., Nakagomi, M., and Yamagata, N. ( 2009) Towards retinoid therapy for Alzheimer's disease. Curr. Alzheimer Res. 6, 302-311.
-
(2009)
Curr. Alzheimer Res.
, vol.6
, pp. 302-311
-
-
Shudo, K.1
Fukasawa, H.2
Nakagomi, M.3
Yamagata, N.4
-
19
-
-
0036626830
-
Re-expression of cell cycle proteins induces neuronal cell death during Alzheimer's disease
-
Herrup, K. and Arendt, T. ( 2002) Re-expression of cell cycle proteins induces neuronal cell death during Alzheimer's disease. J. Alzheimers Dis. 4, 243-247.
-
(2002)
J. Alzheimers Dis.
, vol.4
, pp. 243-247
-
-
Herrup, K.1
Arendt, T.2
-
20
-
-
78650265812
-
DNA damage and cell cycle events implicate cerebellar dentate nucleus neurons as targets of Alzheimer's disease
-
Chen, J., Cohen, M. L., Lerner, A. J., Yang, Y., and Herrup, K. ( 2010) DNA damage and cell cycle events implicate cerebellar dentate nucleus neurons as targets of Alzheimer's disease. Mol. Neurodegener. 5, 60.
-
(2010)
Mol. Neurodegener.
, vol.5
, pp. 60
-
-
Chen, J.1
Cohen, M.L.2
Lerner, A.J.3
Yang, Y.4
Herrup, K.5
-
21
-
-
84859421596
-
Georg Perry Cell cycle activation and the beta-amyloid protein in Alzheimer's disease
-
In Janigro, D., ed.). Humana Press, Totowa, NJ.
-
Gustaw, K. A., Casadesus, G., Friedland, R. P., and Smith, M. A. ( 2005) Georg Perry Cell cycle activation and the beta-amyloid protein in Alzheimer's disease. In Cell Cycle in the Central Nervous System ( Janigro, D., ed.). pp. 299-303, Humana Press, Totowa, NJ.
-
(2005)
Cell Cycle in the Central Nervous System
, pp. 299-303
-
-
Gustaw, K.A.1
Casadesus, G.2
Friedland, R.P.3
Smith, M.A.4
-
22
-
-
79959685557
-
Cell cycle deregulation in the neurons of Alzheimer's disease
-
Moh, C., Kubiak, J. Z., Bajic, V. P., Zhu, X., Smith, M. A., and Lee, H. G. ( 2011) Cell cycle deregulation in the neurons of Alzheimer's disease. Results Probl. Cell Differ. 53, 565-76.
-
(2011)
Results Probl. Cell Differ.
, vol.53
, pp. 565-576
-
-
Moh, C.1
Kubiak, J.Z.2
Bajic, V.P.3
Zhu, X.4
Smith, M.A.5
Lee, H.G.6
-
23
-
-
28044468850
-
Shedding of the amyloid precursor protein-like protein APLP2 by disintegrin-metalloproteinases
-
Endres, K., Postina, R., Schroeder, A., Mueller, U., and Fahrenholz, F. ( 2005) Shedding of the amyloid precursor protein-like protein APLP2 by disintegrin-metalloproteinases. FEBS J. 272, 5808-5820.
-
(2005)
FEBS J.
, vol.272
, pp. 5808-5820
-
-
Endres, K.1
Postina, R.2
Schroeder, A.3
Mueller, U.4
Fahrenholz, F.5
-
24
-
-
24644483112
-
Genomic structure and functional characterization of the human ADAM10 promoter
-
Prinzen, C., Muller, U., Endres, K., Fahrenholz, F., and Postina, R. ( 2005) Genomic structure and functional characterization of the human ADAM10 promoter FASEB J. 19, 1522-1524.
-
(2005)
FASEB J.
, vol.19
, pp. 1522-1524
-
-
Prinzen, C.1
Muller, U.2
Endres, K.3
Fahrenholz, F.4
Postina, R.5
-
25
-
-
77953552933
-
Retinoids as a perspective in treatment of Alzheimer's disease
-
Fahrenholz, F., Tippmann, F., and Endres, K. ( 2010) Retinoids as a perspective in treatment of Alzheimer's disease. Neurodegener. Dis. 7, 190-192
-
(2010)
Neurodegener. Dis.
, vol.7
, pp. 190-192
-
-
Fahrenholz, F.1
Tippmann, F.2
Endres, K.3
-
26
-
-
4544239545
-
Acetylcholinesterase inhibitors increase ADAM10 activity by promoting its trafficking in neuroblastoma cell lines
-
Zimmermann, M., Gardoni, F., Marcello, E., Colciaghi, F., Borroni, B., Padovani, A., Cattabeni, F., and Di Luca, M. ( 2004) Acetylcholinesterase inhibitors increase ADAM10 activity by promoting its trafficking in neuroblastoma cell lines. J. Neurochem. 90, 1489-1499.
-
(2004)
J. Neurochem.
, vol.90
, pp. 1489-1499
-
-
Zimmermann, M.1
Gardoni, F.2
Marcello, E.3
Colciaghi, F.4
Borroni, B.5
Padovani, A.6
Cattabeni, F.7
Di Luca, M.8
-
27
-
-
33750530367
-
Retinoid receptors, transporters, and metabolizers as therapeutic targets in late onsheimer disease
-
Goodman, A. B. ( 2006) Retinoid receptors, transporters, and metabolizers as therapeutic targets in late onset Alzheimer disease. J. Cell Physiol. 209, 598-603.
-
(2006)
J. Cell Physiol.
, vol.209
, pp. 598-603
-
-
Goodman, A.B.1
-
28
-
-
77958518015
-
Tissue-specific increases in endogenous all-trans retinoic acid: possible contributing factor in ethanol toxicity
-
Wolf, G. ( 2010) Tissue-specific increases in endogenous all-trans retinoic acid: possible contributing factor in ethanol toxicity. Nutr. Rev. 68, 689-692.
-
(2010)
Nutr. Rev.
, vol.68
, pp. 689-692
-
-
Wolf, G.1
-
29
-
-
0027223066
-
Conversion of acitretin to etretinate in psoriatic patients is influenced by ethanol
-
Larsen, F. G., Jakobsen, P., Knudsen, J., Weismann, K., Kragballe, K., and Nielsen-Kudsk, F. ( 1993) Conversion of acitretin to etretinate in psoriatic patients is influenced by ethanol. J. Invest. Dermatol. 100, 623-627.
-
(1993)
J. Invest. Dermatol.
, vol.100
, pp. 623-627
-
-
Larsen, F.G.1
Jakobsen, P.2
Knudsen, J.3
Weismann, K.4
Kragballe, K.5
Nielsen-Kudsk, F.6
-
30
-
-
0029887752
-
Trans-acitretin is metabolized back to etretinate. Importance for oral retinoid therapy
-
Almond-Roesler, B. and Orfanos, C. E. ( 1996) Trans-acitretin is metabolized back to etretinate. Importance for oral retinoid therapy. Hautarzt 47, 173-177.
-
(1996)
Hautarzt
, vol.47
, pp. 173-177
-
-
Almond-Roesler, B.1
Orfanos, C.E.2
-
31
-
-
58149268892
-
Retinoic acid attenuates beta-amyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model
-
Ding, Y., Qiao, A., Wang, Z., Goodwin, J. S., Lee, E. S., Block, M. L., Allsbrook, M., McDonald, M. P., and Fan, G. H. ( 2008) Retinoic acid attenuates beta-amyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model. J. Neurosci. 28, 11622-11634.
-
(2008)
J. Neurosci.
, vol.28
, pp. 11622-11634
-
-
Ding, Y.1
Qiao, A.2
Wang, Z.3
Goodwin, J.S.4
Lee, E.S.5
Block, M.L.6
Allsbrook, M.7
McDonald, M.P.8
Fan, G.H.9
-
32
-
-
33644856918
-
The acute and chronic toxic effects of vitamin A
-
Penniston, K. L. and Tanumihardjo, S. A. ( 2006) The acute and chronic toxic effects of vitamin A. Am. J. Clin. Nutr. 83, 191-201.
-
(2006)
Am. J. Clin. Nutr.
, vol.83
, pp. 191-201
-
-
Penniston, K.L.1
Tanumihardjo, S.A.2
-
33
-
-
0038804051
-
Extensive splenic infarction, deep vein thrombosis and pulmonary emboli complicating induction therapy with all-trans-retinoic acid (ATRA) for acute promyelocytic leukemia
-
Goldschmidt, N., Gural, A., and Ben Yehuda, D. ( 2003) Extensive splenic infarction, deep vein thrombosis and pulmonary emboli complicating induction therapy with all-trans-retinoic acid (ATRA) for acute promyelocytic leukemia. Leuk. Lymphoma 44, 1433-1437.
-
(2003)
Leuk. Lymphoma
, vol.44
, pp. 1433-1437
-
-
Goldschmidt, N.1
Gural, A.2
Ben Yehuda, D.3
-
34
-
-
0042830246
-
Retinoic acid syndrome: manifestations, pathogenesis, and treatment
-
Larson, R. S. and Tallman, M. S. ( 2003) Retinoic acid syndrome: manifestations, pathogenesis, and treatment. Best Pract. Res. Clin. Haematol. 16, 453-461.
-
(2003)
Best Pract. Res. Clin. Haematol.
, vol.16
, pp. 453-461
-
-
Larson, R.S.1
Tallman, M.S.2
-
35
-
-
35148882962
-
A phase 2 trial of all-trans-retinoic acid in combination with interferon-alpha2a in children with recurrent neuroblastoma or Wilms tumor: a Pediatric Oncology Branch, NCI and Children's Oncology Group Study
-
Adamson, P. C, Matthay, K. K, O'Brien, M., Reaman, G. H., Sato, J. K., and Balis, F. M. ( 2007) A phase 2 trial of all-trans-retinoic acid in combination with interferon-alpha2a in children with recurrent neuroblastoma or Wilms tumor: a Pediatric Oncology Branch, NCI and Children's Oncology Group Study. Pediatr. Blood Cancer 49, 661-665.
-
(2007)
Pediatr. Blood Cancer
, vol.49
, pp. 661-665
-
-
Adamson, P.C.1
Matthay, K.K.2
O'Brien, M.3
Reaman, G.H.4
Sato, J.K.5
Balis, F.M.6
-
36
-
-
72549105935
-
Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: a randomized controlled trial
-
Tarenflurbil Phase 3 Study Group.
-
Green, R. C., Schneider, L. S., Amato, D. A., Beelen, A. P., Wilcock, G., Swabb, E. A., and Zavitz, K. H. Tarenflurbil Phase 3 Study Group. ( 2009) Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: a randomized controlled trial. JAMA 302, 2557-2564.
-
(2009)
JAMA
, vol.302
, pp. 2557-2564
-
-
Green, R.C.1
Schneider, L.S.2
Amato, D.A.3
Beelen, A.P.4
Wilcock, G.5
Swabb, E.A.6
Zavitz, K.H.7
-
37
-
-
80053336026
-
A randomized, double-blind, placebo-controlled trial of simvastatin to treat Alzheimer disease
-
Sano, M., Bell, K. L., Galasko, D., Galvin, J. E., Thomas, R. G., van Dyck, C. H., and Aisen P. S. ( 2011) A randomized, double-blind, placebo-controlled trial of simvastatin to treat Alzheimer disease. Neurology 77, 556-563.
-
(2011)
Neurology
, vol.77
, pp. 556-563
-
-
Sano, M.1
Bell, K.L.2
Galasko, D.3
Galvin, J.E.4
Thomas, R.G.5
van Dyck, C.H.6
Aisen, P.S.7
-
38
-
-
82255160648
-
Alzheimer's Disease Cooperative Study. Chronic divalproex sodium use and brain atrophy in Alzheimer disease
-
Fleisher, A. S., Truran, D., Mai, J. T., Langbaum, J. B., Aisen, P. S., Cummings, J. L., Jack, C. R. Jr., Weiner, M. W., Thomas, R. G., Schneider, L. S., and Tariot, P. N. ( 2011) Alzheimer's Disease Cooperative Study. Chronic divalproex sodium use and brain atrophy in Alzheimer disease. Neurology 77, 1263-1271.
-
(2011)
Neurology
, vol.77
, pp. 1263-1271
-
-
Fleisher, A.S.1
Truran, D.2
Mai, J.T.3
Langbaum, J.B.4
Aisen, P.S.5
Cummings, J.L.6
Jack Jr, C.R.7
Weiner, M.W.8
Thomas, R.G.9
Schneider, L.S.10
Tariot, P.N.11
-
39
-
-
77950364510
-
Reciprocal roles of SIRT1 and SKIP in the regulation of RAR activity: implication in the retinoic acid-induced neuronal differentiation of P19 cells
-
Kang, M. R., Lee, S. W., Um, E., Kang, H. T., Hwang, E. S., Kim, E. J., and Um, S. J. ( 2010) Reciprocal roles of SIRT1 and SKIP in the regulation of RAR activity: implication in the retinoic acid-induced neuronal differentiation of P19 cells. Nucleic Acids Res. 38, 822-831.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 822-831
-
-
Kang, M.R.1
Lee, S.W.2
Um, E.3
Kang, H.T.4
Hwang, E.S.5
Kim, E.J.6
Um, S.J.7
|