Clioquinol reduces zinc accumulation in neuritic plaques and inhibits the amyloidogenic pathway in aβPP/PS1 transgenic mouse brain

Journal of Alzheimer's Disease

Volumn 29, Issue 3, 2012, Pages 549-559

  Wang, Tao ^a   Wang, Chun Yan ^a,b   Shan, Zhong Yan ^a   Teng, Wei Ping ^a   Wang, Zhan You ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b JILIN MEDICAL COLLEGE   (China)

Author keywords

Alzheimer's disease; amyloid ; amyloidogenic pathway; A PP PS1 transgenic mouse; clioquinol; zinc

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE 1; BETA SECRETASE DERIVED FRAGMENT OF AMYLOID BETA PROTEIN PRECURSOR; CLIOQUINOL; PRESENILIN 1; UNCLASSIFIED DRUG; ZINC;

ALZHEIMER DISEASE; AMYLOIDOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOMETALLOGRAPHY; BIOACCUMULATION; BRAIN CORTEX; CONTROLLED STUDY; HIPPOCAMPUS; MALE; MOUSE; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; SENILE PLAQUE; SYMPTOM; TRANSGENIC MOUSE;

EID: 84859378667     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2011-111874     Document Type: Article

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