Mechanism for the Hydrolysis of Organophosphates by the Bacterial Phosphotriesterase

Biochemistry

Volumn 43, Issue 19, 2004, Pages 5707-5715

  Aubert, Sarah D ^a   Li, Yingchun ^a   Raushel, Frank M ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CATALYSIS; CHEMICAL ACTIVATION; ENZYMES; HYDROLYSIS; OXYGEN; PH EFFECTS; PHOSPHORUS COMPOUNDS; SULFUR; ZINC;

ASPARAGINE MUTATIONS; KINETIC CONSTANTS; ORGANOPHOSPHATES; ZINC METALLOENZYMES;

BIOCHEMISTRY;

4 NITROPHENYLPHOSPHATASE; ALANINE; ASPARAGINE; BACTERIAL ENZYME; CADMIUM DERIVATIVE; CADMIUM PHOSPHOTRIESTERASE; DIETHYL 4 CHLOROPHENYL THIOPHOSPHATE; DIETHYL 6 CHLOROETHYL PHOSPHATE; DIETHYL 6 NITROPHENYL PHOSPHATE; HISTIDINE; HYDROXIDE; METAL ION; METALLOPROTEINASE; ORGANOPHOSPHATE; ORGANOPHOSPHORUS COMPOUND; PARAOXON; PHENOL DERIVATIVE; PHOSPHOTRIESTERASE; UNCLASSIFIED DRUG; ZINC METALLOENZYME; ZINC PHOSPHOTRIESTERASE;

ARTICLE; BREVUNDIMONAS DIMINUTA; CATALYSIS; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME MECHANISM; ENZYME METABOLISM; ENZYME PURIFICATION; HYDROLYSIS; ION TRANSPORT; IONIZATION; LIGATION; NONHUMAN; PH; POLARIZATION; PRIORITY JOURNAL; PROTON TRANSPORT;

ARYLDIALKYLPHOSPHATASE; ASPARTIC ACID; BACTERIAL PROTEINS; CADMIUM; DEUTERIUM EXCHANGE MEASUREMENT; HISTIDINE; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; KINETICS; MODELS, CHEMICAL; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; ORGANOPHOSPHORUS COMPOUNDS; PSEUDOMONAS; SOLVENTS; SUBSTRATE SPECIFICITY; TYROSINE; ZINC;

BACTERIA (MICROORGANISMS); BREVUNDIMONAS DIMINUTA; PSEUDOMONAS;

EID: 2442496666     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0497805     Document Type: Article

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