Nucleophile activation in PD...(D/E)xK metallonucleases: An experimental and computational pKa study

Journal of Inorganic Biochemistry

Volumn 104, Issue 6, 2010, Pages 665-672

  Xie, Fuqian ^a   Briggs, James M ^b   Dupureur, Cynthia M ^a  

^a UNIVERSITY OF MISSOURI ST LOUIS   (United States)

^b University of Houston   (United States)

Author keywords

Mechanism; Metallonuclease; PKa

Indexed keywords

LYSINE; MAGNESIUM; METALLONUCLEASE; NUCLEASE; NUCLEOPHILE; UNCLASSIFIED DRUG; WATER;

ARTICLE; ENZYME ACTIVE SITE; HYDROGEN BOND; MATHEMATICAL COMPUTING; PH; PKA; PREDICTION; PROTEIN MOTIF;

COMPUTATIONAL BIOLOGY; ENDONUCLEASES; HYDROGEN-ION CONCENTRATION; MODELS, BIOLOGICAL; STATIC ELECTRICITY;

EID: 77952542578     PISSN: 01620134     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinorgbio.2010.02.008     Document Type: Article

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