메뉴 건너뛰기




Volumn 209, Issue , 2012, Pages 136-143

Methylene blue administration fails to confer neuroprotection in two amyotrophic lateral sclerosis mouse models

Author keywords

ALS; Methylene blue; Neuroinflammation; Superoxide dismutase; TDP 43

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; LITHIUM SALT; METHYLENE BLUE; TAR DNA BINDING PROTEIN;

EID: 84859265002     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.12.047     Document Type: Article
Times cited : (26)

References (59)
  • 2
    • 0033018506 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase up-regulation in a transgenic mouse model of familial amyotrophic lateral sclerosis
    • Almer G., Vukosavic S., Romero N., Przedborski S. Inducible nitric oxide synthase up-regulation in a transgenic mouse model of familial amyotrophic lateral sclerosis. J Neurochem 1999, 72:2415-2425.
    • (1999) J Neurochem , vol.72 , pp. 2415-2425
    • Almer, G.1    Vukosavic, S.2    Romero, N.3    Przedborski, S.4
  • 3
    • 0034793858 scopus 로고    scopus 로고
    • Glial cells of the spinal cord and subcortical white matter up-regulate neuronal nitric oxide synthase in sporadic amyotrophic lateral sclerosis
    • Anneser J.M., Cookson M.R., Ince P.G., Shaw P.J., Borasio G.D. Glial cells of the spinal cord and subcortical white matter up-regulate neuronal nitric oxide synthase in sporadic amyotrophic lateral sclerosis. Exp Neurol 2001, 171:418-421.
    • (2001) Exp Neurol , vol.171 , pp. 418-421
    • Anneser, J.M.1    Cookson, M.R.2    Ince, P.G.3    Shaw, P.J.4    Borasio, G.D.5
  • 5
    • 77956211109 scopus 로고    scopus 로고
    • Protective role of methylene blue in Alzheimer's disease via mitochondria and cytochrome c oxidase
    • Atamna H., Kumar R. Protective role of methylene blue in Alzheimer's disease via mitochondria and cytochrome c oxidase. J Alzheimers Dis 2010, 20(Suppl 2):S439-S452.
    • (2010) J Alzheimers Dis , vol.20 , Issue.SUPPL. 2
    • Atamna, H.1    Kumar, R.2
  • 6
    • 40449086359 scopus 로고    scopus 로고
    • Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways
    • Atamna H., Nguyen A., Schultz C., Boyle K., Newberry J., Kato H., Ames B.N. Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways. FASEB J 2008, 22:703-712.
    • (2008) FASEB J , vol.22 , pp. 703-712
    • Atamna, H.1    Nguyen, A.2    Schultz, C.3    Boyle, K.4    Newberry, J.5    Kato, H.6    Ames, B.N.7
  • 7
    • 77951622001 scopus 로고    scopus 로고
    • Involvement of nitric oxide-cGMP pathway in the anticonvulsant effects of lithium chloride on PTZ-induced seizure in mice
    • Bahremand A., Nasrabady S.E., Ziai P., Rahimian R., Hedayat T., Payandemehr B., Dehpour A.R. Involvement of nitric oxide-cGMP pathway in the anticonvulsant effects of lithium chloride on PTZ-induced seizure in mice. Epilepsy Res 2010, 89:295-302.
    • (2010) Epilepsy Res , vol.89 , pp. 295-302
    • Bahremand, A.1    Nasrabady, S.E.2    Ziai, P.3    Rahimian, R.4    Hedayat, T.5    Payandemehr, B.6    Dehpour, A.R.7
  • 8
    • 75149155060 scopus 로고    scopus 로고
    • Oxidative stress in ALS: key role in motor neuron injury and therapeutic target
    • Barber S.C., Shaw P.J. Oxidative stress in ALS: key role in motor neuron injury and therapeutic target. Free Radic Biol Med 2010, 48:629-641.
    • (2010) Free Radic Biol Med , vol.48 , pp. 629-641
    • Barber, S.C.1    Shaw, P.J.2
  • 9
    • 84862737980 scopus 로고    scopus 로고
    • The role of RNA processing in the pathogenesis of motor neuron degeneration
    • Baumer D., Ansorge O., Almeida M., Talbot K. The role of RNA processing in the pathogenesis of motor neuron degeneration. Expert Rev Mol Med 2010, 12:e21.
    • (2010) Expert Rev Mol Med , vol.12
    • Baumer, D.1    Ansorge, O.2    Almeida, M.3    Talbot, K.4
  • 10
    • 77954317769 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis and excitotoxicity: from pathological mechanism to therapeutic target
    • Bogaert E., d'Ydewalle C., Van Den Bosch L. Amyotrophic lateral sclerosis and excitotoxicity: from pathological mechanism to therapeutic target. CNS Neurol Disord Drug Targets 2010, 9:297-304.
    • (2010) CNS Neurol Disord Drug Targets , vol.9 , pp. 297-304
    • Bogaert, E.1    d'Ydewalle, C.2    Van Den Bosch, L.3
  • 11
    • 33749056809 scopus 로고    scopus 로고
    • ALS: a disease of motor neurons and their nonneuronal neighbors
    • Boillee S., Vande Velde C., Cleveland D.W. ALS: a disease of motor neurons and their nonneuronal neighbors. Neuron 2006, 52:39-59.
    • (2006) Neuron , vol.52 , pp. 39-59
    • Boillee, S.1    Vande Velde, C.2    Cleveland, D.W.3
  • 16
    • 0343436192 scopus 로고    scopus 로고
    • Reactive astrocytes express nitric oxide synthase in the spinal cord of transgenic mice expressing a human Cu/Zn SOD mutation
    • Cha C.I., Kim J.M., Shin D.H., Kim Y.S., Kim J., Gurney M.E., Lee K.W. Reactive astrocytes express nitric oxide synthase in the spinal cord of transgenic mice expressing a human Cu/Zn SOD mutation. Neuroreport 1998, 9:1503-1506.
    • (1998) Neuroreport , vol.9 , pp. 1503-1506
    • Cha, C.I.1    Kim, J.M.2    Shin, D.H.3    Kim, Y.S.4    Kim, J.5    Gurney, M.E.6    Lee, K.W.7
  • 17
    • 66749133370 scopus 로고    scopus 로고
    • Aggregation of copper-zinc superoxide dismutase in familial and sporadic ALS
    • Chattopadhyay M., Valentine J.S. Aggregation of copper-zinc superoxide dismutase in familial and sporadic ALS. Antioxid Redox Signal 2009, 11:1603-1614.
    • (2009) Antioxid Redox Signal , vol.11 , pp. 1603-1614
    • Chattopadhyay, M.1    Valentine, J.S.2
  • 20
    • 0031280496 scopus 로고    scopus 로고
    • Anxiolytic and antidepressant properties of methylene blue in animal models
    • Eroglu L., Caglayan B. Anxiolytic and antidepressant properties of methylene blue in animal models. Pharmacol Res 1997, 36:381-385.
    • (1997) Pharmacol Res , vol.36 , pp. 381-385
    • Eroglu, L.1    Caglayan, B.2
  • 21
    • 49249136687 scopus 로고    scopus 로고
    • Combined lithium and valproate treatment delays disease onset, reduces neurological deficits and prolongs survival in an amyotrophic lateral sclerosis mouse model
    • Feng H.L., Leng Y., Ma C.H., Zhang J., Ren M., Chuang D.M. Combined lithium and valproate treatment delays disease onset, reduces neurological deficits and prolongs survival in an amyotrophic lateral sclerosis mouse model. Neuroscience 2008, 155:567-572.
    • (2008) Neuroscience , vol.155 , pp. 567-572
    • Feng, H.L.1    Leng, Y.2    Ma, C.H.3    Zhang, J.4    Ren, M.5    Chuang, D.M.6
  • 24
    • 68149136583 scopus 로고    scopus 로고
    • No benefit from chronic lithium dosing in a sibling-matched, gender balanced, investigator-blinded trial using a standard mouse model of familial ALS
    • Gill A., Kidd J., Vieira F., Thompson K., Perrin S. No benefit from chronic lithium dosing in a sibling-matched, gender balanced, investigator-blinded trial using a standard mouse model of familial ALS. PLoS One 2009, 4:e6489.
    • (2009) PLoS One , vol.4
    • Gill, A.1    Kidd, J.2    Vieira, F.3    Thompson, K.4    Perrin, S.5
  • 25
    • 77951924183 scopus 로고    scopus 로고
    • Intracerebroventricular infusion of monoclonal antibody or its derived Fab fragment against misfolded forms of SOD1 mutant delays mortality in a mouse model of ALS
    • Gros-Louis F., Soucy G., Larivière R., Julien J.P. Intracerebroventricular infusion of monoclonal antibody or its derived Fab fragment against misfolded forms of SOD1 mutant delays mortality in a mouse model of ALS. J Neurochem 2010, 113:1188-1199.
    • (2010) J Neurochem , vol.113 , pp. 1188-1199
    • Gros-Louis, F.1    Soucy, G.2    Larivière, R.3    Julien, J.P.4
  • 26
    • 0030690490 scopus 로고    scopus 로고
    • The use of transgenic mouse models of amyotrophic lateral sclerosis in preclinical drug studies
    • Gurney M.E. The use of transgenic mouse models of amyotrophic lateral sclerosis in preclinical drug studies. J Neurol Sci 1997, 152(Suppl 1):S67-S73.
    • (1997) J Neurol Sci , vol.152 , Issue.SUPPL. 1
    • Gurney, M.E.1
  • 28
    • 67749133873 scopus 로고    scopus 로고
    • TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity
    • Johnson B.S., Snead D., Lee J.J., McCaffery J.M., Shorter J., Gitler A.D. TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity. J Biol Chem 2009, 284:20329-20339.
    • (2009) J Biol Chem , vol.284 , pp. 20329-20339
    • Johnson, B.S.1    Snead, D.2    Lee, J.J.3    McCaffery, J.M.4    Shorter, J.5    Gitler, A.D.6
  • 29
    • 77953890823 scopus 로고    scopus 로고
    • TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration
    • Lagier-Tourenne C., Polymenidou M., Cleveland D.W. TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration. Hum Mol Genet 2010, 19:R46-R64.
    • (2010) Hum Mol Genet , vol.19
    • Lagier-Tourenne, C.1    Polymenidou, M.2    Cleveland, D.W.3
  • 30
    • 80053585258 scopus 로고    scopus 로고
    • Lack of effect of methylene blue in the SOD1 G93A mouse model of amyotrophic lateral sclerosis
    • Lougheed R., Turnbull J. Lack of effect of methylene blue in the SOD1 G93A mouse model of amyotrophic lateral sclerosis. PLoS One 2011, 6:e23141.
    • (2011) PLoS One , vol.6
    • Lougheed, R.1    Turnbull, J.2
  • 31
    • 0015939376 scopus 로고
    • Motoneurone disease and ageing
    • McComas A.J., Upton A.R., Sica R.E. Motoneurone disease and ageing. Lancet 1973, 2:1477-1480.
    • (1973) Lancet , vol.2 , pp. 1477-1480
    • McComas, A.J.1    Upton, A.R.2    Sica, R.E.3
  • 32
    • 79251555689 scopus 로고    scopus 로고
    • Methylene blue reduces abeta levels and rescues early cognitive deficit by increasing proteasome activity
    • Medina D.X., Caccamo A., Oddo S. Methylene blue reduces abeta levels and rescues early cognitive deficit by increasing proteasome activity. Brain Pathol 2011, 21:140-149.
    • (2011) Brain Pathol , vol.21 , pp. 140-149
    • Medina, D.X.1    Caccamo, A.2    Oddo, S.3
  • 33
    • 78049439348 scopus 로고    scopus 로고
    • Methylene blue protects the cortical blood-brain barrier against ischemia/reperfusion-induced disruptions
    • Miclescu A., Sharma H.S., Martijn C., Wiklund L. Methylene blue protects the cortical blood-brain barrier against ischemia/reperfusion-induced disruptions. Crit Care Med 2010, 38:2199-2206.
    • (2010) Crit Care Med , vol.38 , pp. 2199-2206
    • Miclescu, A.1    Sharma, H.S.2    Martijn, C.3    Wiklund, L.4
  • 35
    • 0020567599 scopus 로고
    • Methylene blue. A possible treatment for manic depressive psychosis
    • Narsapur S.L., Naylor G.J. Methylene blue. A possible treatment for manic depressive psychosis. J Affect Disord 1983, 5:155-161.
    • (1983) J Affect Disord , vol.5 , pp. 155-161
    • Narsapur, S.L.1    Naylor, G.J.2
  • 36
    • 85003346469 scopus 로고    scopus 로고
    • Toxicology and carcinogenesis studies of methylene blue trihydrate (cas no. 7220-79-3) in F344/N rats and B6C3F1 mice (gavage studies)
    • National Toxicology Program
    • Toxicology and carcinogenesis studies of methylene blue trihydrate (cas no. 7220-79-3) in F344/N rats and B6C3F1 mice (gavage studies). Natl Toxicol Program Tech Rep Ser 2008, 1-224. National Toxicology Program.
    • (2008) Natl Toxicol Program Tech Rep Ser , pp. 1-224
  • 37
    • 0019487319 scopus 로고
    • Possible explanation for therapeutic action of lithium, and a possible substitute (methylene-blue)
    • Naylor G.J., Dick D.A., Johnston B.B., Hopwood S.E., Dick E.G., Smith A.H., Kay D. Possible explanation for therapeutic action of lithium, and a possible substitute (methylene-blue). Lancet 1981, 2:1175-1176.
    • (1981) Lancet , vol.2 , pp. 1175-1176
    • Naylor, G.J.1    Dick, D.A.2    Johnston, B.B.3    Hopwood, S.E.4    Dick, E.G.5    Smith, A.H.6    Kay, D.7
  • 39
    • 77949351725 scopus 로고    scopus 로고
    • Motor neuron disease: systematic reviews of treatment for ALS and SMA
    • Orrell R.W. Motor neuron disease: systematic reviews of treatment for ALS and SMA. Br Med Bull 2010, 93:145-159.
    • (2010) Br Med Bull , vol.93 , pp. 145-159
    • Orrell, R.W.1
  • 40
    • 0033948654 scopus 로고    scopus 로고
    • Pharmacokinetics and organ distribution of intravenous and oral methylene blue
    • Peter C., Hongwan D., Küpfer A., Lauterburg B.H. Pharmacokinetics and organ distribution of intravenous and oral methylene blue. Eur J Clin Pharmacol 2000, 56:247-250.
    • (2000) Eur J Clin Pharmacol , vol.56 , pp. 247-250
    • Peter, C.1    Hongwan, D.2    Küpfer, A.3    Lauterburg, B.H.4
  • 41
    • 68149100027 scopus 로고    scopus 로고
    • Treatment with lithium carbonate does not improve disease progression in two different strains of SOD1 mutant mice
    • Pizzasegola C., Caron I., Daleno C., Ronchi A., Minoia C., Carrì M.T., Bendotti C. Treatment with lithium carbonate does not improve disease progression in two different strains of SOD1 mutant mice. Amyotroph Lateral Scler 2009, 10:221-228.
    • (2009) Amyotroph Lateral Scler , vol.10 , pp. 221-228
    • Pizzasegola, C.1    Caron, I.2    Daleno, C.3    Ronchi, A.4    Minoia, C.5    Carrì, M.T.6    Bendotti, C.7
  • 42
    • 79952834573 scopus 로고    scopus 로고
    • Mitochondrial disfunction as a cause of ALS
    • Pizzuti A., Petrucci S. Mitochondrial disfunction as a cause of ALS. Arch Ital Biol 2011, 149:113-119.
    • (2011) Arch Ital Biol , vol.149 , pp. 113-119
    • Pizzuti, A.1    Petrucci, S.2
  • 43
    • 68749083546 scopus 로고    scopus 로고
    • Variation in aggregation propensities among ALS-associated variants of SOD1: correlation to human disease
    • Prudencio M., Hart P.J., Borchelt D.R., Andersen P.M. Variation in aggregation propensities among ALS-associated variants of SOD1: correlation to human disease. Hum Mol Genet 2009, 18:3217-3226.
    • (2009) Hum Mol Genet , vol.18 , pp. 3217-3226
    • Prudencio, M.1    Hart, P.J.2    Borchelt, D.R.3    Andersen, P.M.4
  • 44
    • 78650939779 scopus 로고    scopus 로고
    • Beneficial network effects of methylene blue in an amnestic model
    • Riha P.D., Rojas J.C., Gonzalez-Lima F. Beneficial network effects of methylene blue in an amnestic model. Neuroimage 2011, 54:2623-2634.
    • (2011) Neuroimage , vol.54 , pp. 2623-2634
    • Riha, P.D.1    Rojas, J.C.2    Gonzalez-Lima, F.3
  • 45
    • 0035031371 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase immunoreactivity in the spinal cord in amyotrophic lateral sclerosis
    • Sasaki S., Shibata N., Iwata M. Neuronal nitric oxide synthase immunoreactivity in the spinal cord in amyotrophic lateral sclerosis. Acta Neuropathol 2001, 101:351-357.
    • (2001) Acta Neuropathol , vol.101 , pp. 351-357
    • Sasaki, S.1    Shibata, N.2    Iwata, M.3
  • 46
    • 0036938073 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase (nNOS) immunoreactivity in the spinal cord of transgenic mice with G93A mutant SOD1 gene
    • Sasaki S., Warita H., Abe K., Iwata M. Neuronal nitric oxide synthase (nNOS) immunoreactivity in the spinal cord of transgenic mice with G93A mutant SOD1 gene. Acta Neuropathol 2002, 103:421-427.
    • (2002) Acta Neuropathol , vol.103 , pp. 421-427
    • Sasaki, S.1    Warita, H.2    Abe, K.3    Iwata, M.4
  • 48
    • 33947363215 scopus 로고    scopus 로고
    • Concurrent administration of Neu2000 and lithium produces marked improvement of motor neuron survival, motor function, and mortality in a mouse model of amyotrophic lateral sclerosis
    • Shin J.H., Cho S.I., Lim H.R., Lee J.K., Lee Y.A., Noh J.S., Joo I.S., Kim K.W., Gwag B.J. Concurrent administration of Neu2000 and lithium produces marked improvement of motor neuron survival, motor function, and mortality in a mouse model of amyotrophic lateral sclerosis. Mol Pharmacol 2007, 71:965-975.
    • (2007) Mol Pharmacol , vol.71 , pp. 965-975
    • Shin, J.H.1    Cho, S.I.2    Lim, H.R.3    Lee, J.K.4    Lee, Y.A.5    Noh, J.S.6    Joo, I.S.7    Kim, K.W.8    Gwag, B.J.9
  • 49
    • 80052936462 scopus 로고    scopus 로고
    • Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments
    • Swarup V., Phaneuf D., Bareil C., Robertson J., Rouleau G.A., Kriz J., Julien J.P. Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments. Brain 2011, 134:2610-2626.
    • (2011) Brain , vol.134 , pp. 2610-2626
    • Swarup, V.1    Phaneuf, D.2    Bareil, C.3    Robertson, J.4    Rouleau, G.A.5    Kriz, J.6    Julien, J.P.7
  • 50
    • 14844303721 scopus 로고    scopus 로고
    • Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins
    • Taniguchi S., Suzuki N., Masuda M., Hisanaga S., Iwatsubo T., Goedert M., Hasegawa M. Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins. J Biol Chem 2005, 280:7614-7623.
    • (2005) J Biol Chem , vol.280 , pp. 7614-7623
    • Taniguchi, S.1    Suzuki, N.2    Masuda, M.3    Hisanaga, S.4    Iwatsubo, T.5    Goedert, M.6    Hasegawa, M.7
  • 51
    • 77954372835 scopus 로고    scopus 로고
    • Protein aggregation and defective RNA metabolism as mechanisms for motor neuron damage
    • Ticozzi N., Ratti A., Silani V. Protein aggregation and defective RNA metabolism as mechanisms for motor neuron damage. CNS Neurol Disord Drug Targets 2010, 9:285-296.
    • (2010) CNS Neurol Disord Drug Targets , vol.9 , pp. 285-296
    • Ticozzi, N.1    Ratti, A.2    Silani, V.3
  • 52
    • 42249102078 scopus 로고    scopus 로고
    • Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS
    • Turner B.J., Talbot K. Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS. Prog Neurobiol 2008, 85:94-134.
    • (2008) Prog Neurobiol , vol.85 , pp. 94-134
    • Turner, B.J.1    Talbot, K.2
  • 53
    • 29444443348 scopus 로고    scopus 로고
    • Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis
    • Urushitani M., Sik A., Sakurai T., Nukina N., Takahashi R., Julien J.P. Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis. Nat Neurosci 2006, 9:108-118.
    • (2006) Nat Neurosci , vol.9 , pp. 108-118
    • Urushitani, M.1    Sik, A.2    Sakurai, T.3    Nukina, N.4    Takahashi, R.5    Julien, J.P.6
  • 54
    • 26444542945 scopus 로고    scopus 로고
    • Somatodendritic accumulation of misfolded SOD1-L126Z in motor neurons mediates degeneration: alphaB-crystallin modulates aggregation
    • Wang J., Xu G., Li H., Gonzales V., Fromholt D., Karch C., Copeland N.G., Jenkins N.A., Borchelt D.R. Somatodendritic accumulation of misfolded SOD1-L126Z in motor neurons mediates degeneration: alphaB-crystallin modulates aggregation. Hum Mol Genet 2005, 14:2335-2347.
    • (2005) Hum Mol Genet , vol.14 , pp. 2335-2347
    • Wang, J.1    Xu, G.2    Li, H.3    Gonzales, V.4    Fromholt, D.5    Karch, C.6    Copeland, N.G.7    Jenkins, N.A.8    Borchelt, D.R.9
  • 56
    • 37049024934 scopus 로고    scopus 로고
    • Neuro- and cardioprotective effects of blockade of nitric oxide action by administration of methylene blue
    • Wiklund L., Basu S., Miclescu A., Wiklund P., Ronquist G., Sharma H.S. Neuro- and cardioprotective effects of blockade of nitric oxide action by administration of methylene blue. Ann N Y Acad Sci 2007, 1122:231-244.
    • (2007) Ann N Y Acad Sci , vol.1122 , pp. 231-244
    • Wiklund, L.1    Basu, S.2    Miclescu, A.3    Wiklund, P.4    Ronquist, G.5    Sharma, H.S.6
  • 58
    • 0029053881 scopus 로고
    • An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
    • Wong P.C., Pardo C.A., Borchelt D.R., Lee M.K., Copeland N.G., Jenkins N.A., Sisodia S.S., Cleveland D.W., Price D.L. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron 1995, 14:1105-1116.
    • (1995) Neuron , vol.14 , pp. 1105-1116
    • Wong, P.C.1    Pardo, C.A.2    Borchelt, D.R.3    Lee, M.K.4    Copeland, N.G.5    Jenkins, N.A.6    Sisodia, S.S.7    Cleveland, D.W.8    Price, D.L.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.