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Volumn 32, Issue 12, 2011, Pages 2325.e7-2325.e16

"Lest we forget you - methylene blue..."

Author keywords

Alzheimer's disease; History; Malaria therapy; Medical application; Methylene blue; Prodrug of azure B; Tau aggregation inhibitor

Indexed keywords

AMYLOID BETA PROTEIN; AZURE B; GLUTATHIONE REDUCTASE; IFOSFAMIDE; METHYLENE BLUE; PYOCYANINE; REMBER; RIVASTIGMINE; SELENIUM; SEROTONIN UPTAKE INHIBITOR; TAU PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 79955674414     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2010.12.012     Document Type: Article
Times cited : (312)

References (82)
  • 2
    • 27644471426 scopus 로고    scopus 로고
    • In vitro assessment of methylene blue on chloroquine-sensitive and -resistant Plasmodium falciparum strains reveals synergistic action with artemisinins
    • Akoachere M., Buchholz K., Fischer E., Burhenne J., Haefeli W.E., Schirmer R.H., Becker K. In vitro assessment of methylene blue on chloroquine-sensitive and -resistant Plasmodium falciparum strains reveals synergistic action with artemisinins. Antimicrob. Agents Chemother 2005, 49:4592-4597.
    • (2005) Antimicrob. Agents Chemother , vol.49 , pp. 4592-4597
    • Akoachere, M.1    Buchholz, K.2    Fischer, E.3    Burhenne, J.4    Haefeli, W.E.5    Schirmer, R.H.6    Becker, K.7
  • 4
    • 77956211109 scopus 로고    scopus 로고
    • Protective role of methylene blue in Alzheimer's disease via mitochondria and cytochrome c oxidase
    • Atamna H., Kumar R. Protective role of methylene blue in Alzheimer's disease via mitochondria and cytochrome c oxidase. J. Alzheimers Dis 2010, 20:S439-S452.
    • (2010) J. Alzheimers Dis , vol.20
    • Atamna, H.1    Kumar, R.2
  • 5
    • 0029987752 scopus 로고    scopus 로고
    • Mode of antimalarial effect of methylene blue and some of its analogues on Plasmodium falciparum in culture and their inhibition of P. vinckei petteri and P. yoelii nigeriensis in vivo
    • Atamna H., Krugliak M., Shalmiev G., Deharo E., Pescarmona G., Ginsburg H. Mode of antimalarial effect of methylene blue and some of its analogues on Plasmodium falciparum in culture and their inhibition of P. vinckei petteri and P. yoelii nigeriensis in vivo. Biochem. Pharmacol 1996, 51:693-700.
    • (1996) Biochem. Pharmacol , vol.51 , pp. 693-700
    • Atamna, H.1    Krugliak, M.2    Shalmiev, G.3    Deharo, E.4    Pescarmona, G.5    Ginsburg, H.6
  • 6
    • 40449086359 scopus 로고    scopus 로고
    • Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways
    • Atamna H., Nguyen A., Schultz C., Boyle K., Newberry J., Kato H., Ames B.N. Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways. FASEB J 2008, 22:703-712.
    • (2008) FASEB J , vol.22 , pp. 703-712
    • Atamna, H.1    Nguyen, A.2    Schultz, C.3    Boyle, K.4    Newberry, J.5    Kato, H.6    Ames, B.N.7
  • 7
    • 34250889472 scopus 로고    scopus 로고
    • The Giemsa stain: its history and applications
    • Barcia J.J. The Giemsa stain: its history and applications. Int. J. Surg. Pathol 2007, 15:292-296.
    • (2007) Int. J. Surg. Pathol , vol.15 , pp. 292-296
    • Barcia, J.J.1
  • 8
    • 0000871453 scopus 로고
    • Dell'azione sedativa del bleu di metilene in varie forme di psicosi
    • Bodoni P. Dell'azione sedativa del bleu di metilene in varie forme di psicosi. Clin. Med. Ital 1899, 21:217-222.
    • (1899) Clin. Med. Ital , vol.21 , pp. 217-222
    • Bodoni, P.1
  • 10
    • 52949150369 scopus 로고    scopus 로고
    • Behavioral, physiological and biochemical hormetic responses to the autoxidizable dye methylene blue
    • Bruchey A.K., Gonzales-Lima F. Behavioral, physiological and biochemical hormetic responses to the autoxidizable dye methylene blue. Am. J. Pharmacol. Toxicol 2008, 3:72-79.
    • (2008) Am. J. Pharmacol. Toxicol , vol.3 , pp. 72-79
    • Bruchey, A.K.1    Gonzales-Lima, F.2
  • 13
    • 0021488479 scopus 로고
    • Methylene blue: effects and disposition in sheep
    • Burrows G.E. Methylene blue: effects and disposition in sheep. J. Vet. Pharmacol. Ther 1984, 7:225-231.
    • (1984) J. Vet. Pharmacol. Ther , vol.7 , pp. 225-231
    • Burrows, G.E.1
  • 14
    • 12744271691 scopus 로고
    • El azul de metileno en los centros nerviosos
    • Cajal S. El azul de metileno en los centros nerviosos. Rev. Trimest. Microgr 1896, 1:151-203.
    • (1896) Rev. Trimest. Microgr , vol.1 , pp. 151-203
    • Cajal, S.1
  • 15
    • 80053643658 scopus 로고
    • Methylene blue in grave malaria cachexia
    • Cardamatis A. Methylene blue in grave malaria cachexia. JAMA 1900, 34:1408-1409.
    • (1900) JAMA , vol.34 , pp. 1408-1409
    • Cardamatis, A.1
  • 17
    • 66749176089 scopus 로고    scopus 로고
    • Structure-activity relationship of cyanine tau aggregation inhibitors
    • Chang E., Congdon E.E., Honson N.S., Duff K.E., Kuret J. Structure-activity relationship of cyanine tau aggregation inhibitors. J. Med. Chem 2009, 52:3539-3547.
    • (2009) J. Med. Chem , vol.52 , pp. 3539-3547
    • Chang, E.1    Congdon, E.E.2    Honson, N.S.3    Duff, K.E.4    Kuret, J.5
  • 18
    • 0001684744 scopus 로고
    • Studies on oxidation-reduction. VIII. Methylene blue
    • Clark W.M., Cohen B., Gibbs H.D. Studies on oxidation-reduction. VIII. Methylene blue. U. S. Pub Health Rep 1925, 40:1131-1201.
    • (1925) U. S. Pub Health Rep , vol.40 , pp. 1131-1201
    • Clark, W.M.1    Cohen, B.2    Gibbs, H.D.3
  • 21
    • 59449097789 scopus 로고    scopus 로고
    • Methylthioninium chloride reverses cognitive deficits induced by scopolamine: comparison with rivastigmine
    • Deiana S., Harrington C.R., Wischik C.M., Riedel G. Methylthioninium chloride reverses cognitive deficits induced by scopolamine: comparison with rivastigmine. Psychopharmacology (Berl) 2009, 202:53-65.
    • (2009) Psychopharmacology (Berl) , vol.202 , pp. 53-65
    • Deiana, S.1    Harrington, C.R.2    Wischik, C.M.3    Riedel, G.4
  • 22
    • 33747082622 scopus 로고    scopus 로고
    • The phenazine pyocyanin is a terminal signalling factor in the quorum sensing network of Pseudomonas aeruginosa
    • Dietrich L.E., Price-Whelan A., Petersen A., Whiteley M., Newman D.K. The phenazine pyocyanin is a terminal signalling factor in the quorum sensing network of Pseudomonas aeruginosa. Mol. Microbiol 2006, 61:1308-1321.
    • (2006) Mol. Microbiol , vol.61 , pp. 1308-1321
    • Dietrich, L.E.1    Price-Whelan, A.2    Petersen, A.3    Whiteley, M.4    Newman, D.K.5
  • 23
    • 50649098819 scopus 로고    scopus 로고
    • Redox-active antibiotics control gene expression and community behavior in divergent bacteria
    • Dietrich L.E., Teal T.K., Price-Whelan A., Newman D.K. Redox-active antibiotics control gene expression and community behavior in divergent bacteria. Science 2008, 321:1203-1206.
    • (2008) Science , vol.321 , pp. 1203-1206
    • Dietrich, L.E.1    Teal, T.K.2    Price-Whelan, A.3    Newman, D.K.4
  • 24
    • 0012524261 scopus 로고
    • Über die Methylenblaureaktion der lebenden Nervensubstanz
    • Ehrlich P. Über die Methylenblaureaktion der lebenden Nervensubstanz. Dtsch. Med. Wochenschr 1886, 12:49-52.
    • (1886) Dtsch. Med. Wochenschr , vol.12 , pp. 49-52
    • Ehrlich, P.1
  • 25
    • 0013506336 scopus 로고
    • Über Schmerzstillende Wirkung des Methylenblau
    • Ehrlich P., Leppmann A. Über Schmerzstillende Wirkung des Methylenblau. Dtsch. Med. Wochenschr 1890, 16:493-494.
    • (1890) Dtsch. Med. Wochenschr , vol.16 , pp. 493-494
    • Ehrlich, P.1    Leppmann, A.2
  • 26
    • 0043096998 scopus 로고    scopus 로고
    • Recombinant Plasmodium falciparum glutathione reductase is inhibited by the antimalarial dye methylene blue
    • Färber P.M., Arscott L.D., Williams C.H., Becker K., Schirmer R.H. Recombinant Plasmodium falciparum glutathione reductase is inhibited by the antimalarial dye methylene blue. FEBS Lett 1998, 422:311-314.
    • (1998) FEBS Lett , vol.422 , pp. 311-314
    • Färber, P.M.1    Arscott, L.D.2    Williams, C.H.3    Becker, K.4    Schirmer, R.H.5
  • 27
    • 3242719401 scopus 로고    scopus 로고
    • Editorial: 100 years ago: Giemsa's solution for staining of plasmodia
    • Fleischer B. Editorial: 100 years ago: Giemsa's solution for staining of plasmodia. Trop. Med. Int. Health 2004, 9:755-756.
    • (2004) Trop. Med. Int. Health , vol.9 , pp. 755-756
    • Fleischer, B.1
  • 28
    • 34648837296 scopus 로고    scopus 로고
    • The discovery of dendritic spines by Cajal in 1888 and its relevance in the present neuroscience
    • Garcia-Lopez P., Garcia-Marin V., Freire M. The discovery of dendritic spines by Cajal in 1888 and its relevance in the present neuroscience. Prog. Neurobiol 2007, 83:110-130.
    • (2007) Prog. Neurobiol , vol.83 , pp. 110-130
    • Garcia-Lopez, P.1    Garcia-Marin, V.2    Freire, M.3
  • 29
    • 12344304237 scopus 로고    scopus 로고
    • Determination of methylene blue and leucomethylene blue in male and female Fischer 344 rat urine and B6C3F1 mouse urine
    • Gaudette N.F., Lodge J.W. Determination of methylene blue and leucomethylene blue in male and female Fischer 344 rat urine and B6C3F1 mouse urine. J. Anal. Toxicol 2005, 29:28-33.
    • (2005) J. Anal. Toxicol , vol.29 , pp. 28-33
    • Gaudette, N.F.1    Lodge, J.W.2
  • 30
    • 51349134160 scopus 로고    scopus 로고
    • Hope in Alzheimer's fight emerges from unexpected places
    • Gura T. Hope in Alzheimer's fight emerges from unexpected places. Nat. Med 2008, 14:894.
    • (2008) Nat. Med , vol.14 , pp. 894
    • Gura, T.1
  • 31
    • 43249094217 scopus 로고    scopus 로고
    • Cation exchange resins as pharmaceutical carriers for methylene blue: binding and release
    • Gut F., Schiek W., Haefeli W.E., Walter-Sack I., Burhenne J. Cation exchange resins as pharmaceutical carriers for methylene blue: binding and release. Eur. J. Pharm. Biopharm 2008, 69:582-587.
    • (2008) Eur. J. Pharm. Biopharm , vol.69 , pp. 582-587
    • Gut, F.1    Schiek, W.2    Haefeli, W.E.3    Walter-Sack, I.4    Burhenne, J.5
  • 32
    • 0000073101 scopus 로고
    • Über die Wirkung des Methylenblau bei Malaria
    • Guttmann P., Ehrlich P. Über die Wirkung des Methylenblau bei Malaria. Berlin. Klin. Woch 1891, 28:953-956.
    • (1891) Berlin. Klin. Woch , vol.28 , pp. 953-956
    • Guttmann, P.1    Ehrlich, P.2
  • 33
    • 77957016764 scopus 로고    scopus 로고
    • Role of monoamine oxidase, nitric oxide synthase and regional brain monoamines in the antidepressant-like effects of methylene blue and selected structural analogues
    • Harvey B.H., Duvenhage I., Viljoen F., Scheepers N., Malan S.F., Wegener G., Brink C.B., Petzer J.P. Role of monoamine oxidase, nitric oxide synthase and regional brain monoamines in the antidepressant-like effects of methylene blue and selected structural analogues. Biochem. Pharmacol 2010, 80:1580-1591.
    • (2010) Biochem. Pharmacol , vol.80 , pp. 1580-1591
    • Harvey, B.H.1    Duvenhage, I.2    Viljoen, F.3    Scheepers, N.4    Malan, S.F.5    Wegener, G.6    Brink, C.B.7    Petzer, J.P.8
  • 35
    • 0026095584 scopus 로고
    • Determination of macromolecular structures from anomalous diffraction of synchrotron radiation
    • Hendrickson W.A. Determination of macromolecular structures from anomalous diffraction of synchrotron radiation. Science 1991, 254:51-58.
    • (1991) Science , vol.254 , pp. 51-58
    • Hendrickson, W.A.1
  • 36
    • 53349144370 scopus 로고    scopus 로고
    • The natively unfolded character of tau and its aggregation to Alzheimer-like paired helical filaments
    • Jeganathan S., von Bergen M., Mandelkow E.M., Mandelkow E. The natively unfolded character of tau and its aggregation to Alzheimer-like paired helical filaments. Biochemistry 2008, 47:10526-10539.
    • (2008) Biochemistry , vol.47 , pp. 10526-10539
    • Jeganathan, S.1    von Bergen, M.2    Mandelkow, E.M.3    Mandelkow, E.4
  • 39
    • 56749083655 scopus 로고    scopus 로고
    • Serotonin toxicity precipitated by concomitant use of citalopram and methylene blue
    • Khavandi A., Whitaker J., Gonna H. Serotonin toxicity precipitated by concomitant use of citalopram and methylene blue. Med. J. Aust 2008, 189:534-535.
    • (2008) Med. J. Aust , vol.189 , pp. 534-535
    • Khavandi, A.1    Whitaker, J.2    Gonna, H.3
  • 41
    • 0024605172 scopus 로고
    • Dyes, antipsychotic drugs, and antimicrobial activity. Fragments of a development, with special reference to the influence of Paul Ehrlich
    • Kristiansen J.E. Dyes, antipsychotic drugs, and antimicrobial activity. Fragments of a development, with special reference to the influence of Paul Ehrlich. Dan. Med. Bull 1989, 36:178-185.
    • (1989) Dan. Med. Bull , vol.36 , pp. 178-185
    • Kristiansen, J.E.1
  • 42
    • 67449147108 scopus 로고    scopus 로고
    • The brain selenoproteome: priorities in the hierarchy and different levels of selenium homeostasis in the brain of selenium-deficient rats
    • Kühbacher M., Bartel J., Hoppe B., Alber D., Bukalis G., Bräuer A.U., Behne D., Kyriakopoulos A. The brain selenoproteome: priorities in the hierarchy and different levels of selenium homeostasis in the brain of selenium-deficient rats. J. Neurochem 2009, 110:133-142.
    • (2009) J. Neurochem , vol.110 , pp. 133-142
    • Kühbacher, M.1    Bartel, J.2    Hoppe, B.3    Alber, D.4    Bukalis, G.5    Bräuer, A.U.6    Behne, D.7    Kyriakopoulos, A.8
  • 43
    • 0018820331 scopus 로고
    • Regional intracellular pH shift: a proposed new mechanism for radiopharmaceutical uptake in brain and other tissues
    • Kung H.F., Blau M. Regional intracellular pH shift: a proposed new mechanism for radiopharmaceutical uptake in brain and other tissues. J. Nucl. Med 1980, 21:147-152.
    • (1980) J. Nucl. Med , vol.21 , pp. 147-152
    • Kung, H.F.1    Blau, M.2
  • 44
    • 0028280955 scopus 로고
    • Prophylaxis and reversal of ifosfamid encephalopathy with methylene-blue
    • Kupfer A., Aeschlimann C., Wermuth B., Cerny T. Prophylaxis and reversal of ifosfamid encephalopathy with methylene-blue. Lancet 1994, 343:763-764.
    • (1994) Lancet , vol.343 , pp. 763-764
    • Kupfer, A.1    Aeschlimann, C.2    Wermuth, B.3    Cerny, T.4
  • 45
    • 85058205089 scopus 로고    scopus 로고
    • Lebensbedrohliche Kreislaufreaktionen auf Toluidinblau
    • Ludwig S., Baethge C. Lebensbedrohliche Kreislaufreaktionen auf Toluidinblau. Deutsches Ärzteblatt 2010, 107:C1308.
    • (2010) Deutsches Ärzteblatt , vol.107
    • Ludwig, S.1    Baethge, C.2
  • 46
    • 0040341187 scopus 로고
    • and 2001, Bluejacket Books, Annapolis, MD
    • MacArthur D. Reminiscences 1964, and 2001, Bluejacket Books, Annapolis, MD. 2nd Edition.
    • (1964) Reminiscences
    • MacArthur, D.1
  • 47
    • 85011939528 scopus 로고    scopus 로고
    • Methylene blue reduces Abeta levels and rescues early cognitive deficit by increasing proteasome activity
    • in press
    • Medina D.X., Caccamo A., Oddo S. Methylene blue reduces Abeta levels and rescues early cognitive deficit by increasing proteasome activity. Brain Pathol 2010, in press.
    • (2010) Brain Pathol
    • Medina, D.X.1    Caccamo, A.2    Oddo, S.3
  • 48
    • 1642333730 scopus 로고    scopus 로고
    • Intradermal methylene blue injection for the treatment of intractable idiopathic pruritus ani: results of 30 cases
    • Mentes B.B., Akin M., Leventoglu S., Gultekin F.A., Oguz M. Intradermal methylene blue injection for the treatment of intractable idiopathic pruritus ani: results of 30 cases. Tech. Coloproctol 2004, 8:11-14.
    • (2004) Tech. Coloproctol , vol.8 , pp. 11-14
    • Mentes, B.B.1    Akin, M.2    Leventoglu, S.3    Gultekin, F.A.4    Oguz, M.5
  • 51
    • 0022552935 scopus 로고
    • A two-year double-blind crossover trial of the prophylactic effect of methylene blue in manic depressive psychosis
    • Naylor G.J., Martin B., Hopwood S.E., Watson Y. A two-year double-blind crossover trial of the prophylactic effect of methylene blue in manic depressive psychosis. Biol. Psychiatry 1986, 21:915-920.
    • (1986) Biol. Psychiatry , vol.21 , pp. 915-920
    • Naylor, G.J.1    Martin, B.2    Hopwood, S.E.3    Watson, Y.4
  • 53
    • 68449087508 scopus 로고    scopus 로고
    • An update on treatment and prevention strategies for Alzheimer's disease
    • Neugroschl J., Sano M. An update on treatment and prevention strategies for Alzheimer's disease. Curr. Neurol. Neurosci. Rep 2009, 9:368-376.
    • (2009) Curr. Neurol. Neurosci. Rep , vol.9 , pp. 368-376
    • Neugroschl, J.1    Sano, M.2
  • 54
    • 75649105019 scopus 로고    scopus 로고
    • Current treatment and recent clinical research in Alzheimer's disease
    • Neugroschl J., Sano M. Current treatment and recent clinical research in Alzheimer's disease. Mt Sinai. J. Med 2010, 77:3-16.
    • (2010) Mt Sinai. J. Med , vol.77 , pp. 3-16
    • Neugroschl, J.1    Sano, M.2
  • 55
    • 84907126319 scopus 로고
    • Supravital staining of mammalian brain with intra-arterial methylene blue followed by pressurized oxygen
    • O'Leary J.L., Petty J., Harris A.B., Inukai J. Supravital staining of mammalian brain with intra-arterial methylene blue followed by pressurized oxygen. Stain Technol 1968, 43:197-201.
    • (1968) Stain Technol , vol.43 , pp. 197-201
    • O'Leary, J.L.1    Petty, J.2    Harris, A.B.3    Inukai, J.4
  • 56
    • 78650018920 scopus 로고    scopus 로고
    • Cellular and molecular actions of methylene blue in the nervous system
    • Oz M., Lorke D.E., Hasan M., Petroianu G.A. Cellular and molecular actions of methylene blue in the nervous system. Med. Res. Rev 2011, 31:93-117.
    • (2011) Med. Res. Rev , vol.31 , pp. 93-117
    • Oz, M.1    Lorke, D.E.2    Hasan, M.3    Petroianu, G.A.4
  • 58
    • 0033985032 scopus 로고    scopus 로고
    • Methylene blue in the treatment and prevention of ifosfamide-induced encephalopathy: report of 12 cases and a review of the literature
    • Pelgrims J., De Vos F., Van den Brande J., Schrijvers D., Prove A., Vermorken J.B. Methylene blue in the treatment and prevention of ifosfamide-induced encephalopathy: report of 12 cases and a review of the literature. Br. J. Cancer 2000, 82:291-294.
    • (2000) Br. J. Cancer , vol.82 , pp. 291-294
    • Pelgrims, J.1    De Vos, F.2    Van den Brande, J.3    Schrijvers, D.4    Prove, A.5    Vermorken, J.B.6
  • 59
    • 0033948654 scopus 로고    scopus 로고
    • Pharmacokinetics and organ distribution of intravenous and oral methylene blue
    • Peter C., Hongwan D., Kupfer A., Lauterburg B.H. Pharmacokinetics and organ distribution of intravenous and oral methylene blue. Eur. J. Clin. Pharmacol 2000, 56:247-250.
    • (2000) Eur. J. Clin. Pharmacol , vol.56 , pp. 247-250
    • Peter, C.1    Hongwan, D.2    Kupfer, A.3    Lauterburg, B.H.4
  • 61
    • 34548502687 scopus 로고    scopus 로고
    • Phenylthiazolyl-hydrazide and its derivatives are potent inhibitors of tau aggregation and toxicity in vitro and in cells
    • Pickhardt M., Larbig G., Khlistunova I., Coksezen A., Meyer B., Mandelkow E.M., Schmidt B., Mandelkow E. Phenylthiazolyl-hydrazide and its derivatives are potent inhibitors of tau aggregation and toxicity in vitro and in cells. Biochemistry 2007, 46:10016-10023.
    • (2007) Biochemistry , vol.46 , pp. 10016-10023
    • Pickhardt, M.1    Larbig, G.2    Khlistunova, I.3    Coksezen, A.4    Meyer, B.5    Mandelkow, E.M.6    Schmidt, B.7    Mandelkow, E.8
  • 62
    • 36048982476 scopus 로고    scopus 로고
    • Methylene blue and serotonin toxicity: inhibition of monoamine oxidase A (MAO A) confirms a theoretical prediction
    • Ramsay R.R., Dunford C., Gillman P.K. Methylene blue and serotonin toxicity: inhibition of monoamine oxidase A (MAO A) confirms a theoretical prediction. Br. J. Pharmacol 2007, 152:946-951.
    • (2007) Br. J. Pharmacol , vol.152 , pp. 946-951
    • Ramsay, R.R.1    Dunford, C.2    Gillman, P.K.3
  • 63
    • 15744371610 scopus 로고    scopus 로고
    • Memory facilitation by methylene blue: dose-dependent effect on behavior and brain oxygen consumption
    • Riha P.D., Bruchey A.K., Echevarria D.J., Gonzalez-Lima F. Memory facilitation by methylene blue: dose-dependent effect on behavior and brain oxygen consumption. Eur. J. Pharmacol 2005, 511:151-158.
    • (2005) Eur. J. Pharmacol , vol.511 , pp. 151-158
    • Riha, P.D.1    Bruchey, A.K.2    Echevarria, D.J.3    Gonzalez-Lima, F.4
  • 64
    • 0037427472 scopus 로고    scopus 로고
    • Glutathione reductase of the malarial parasite Plasmodium falciparum: Crystal structure and inhibitor development
    • Sarma G.N., Savvides S.N., Becker K., Schirmer M., Schirmer R.H., Karplus P.A. Glutathione reductase of the malarial parasite Plasmodium falciparum: Crystal structure and inhibitor development. J. Mol. Biol 2003, 328:893-907.
    • (2003) J. Mol. Biol , vol.328 , pp. 893-907
    • Sarma, G.N.1    Savvides, S.N.2    Becker, K.3    Schirmer, M.4    Schirmer, R.H.5    Karplus, P.A.6
  • 65
    • 0029873477 scopus 로고    scopus 로고
    • Kinetics and crystallographic analysis of human glutathione reductase in complex with a xanthene inhibitor
    • Savvides S.N., Karplus P.A. Kinetics and crystallographic analysis of human glutathione reductase in complex with a xanthene inhibitor. J. Biol. Chem 1996, 271:8101-8107.
    • (1996) J. Biol. Chem , vol.271 , pp. 8101-8107
    • Savvides, S.N.1    Karplus, P.A.2
  • 66
    • 80053643475 scopus 로고    scopus 로고
    • Disulfide reductases as drug targets: methylene blue combination therapies for falciparum malaria in African children
    • Prensas Universitarias de Zaragoza, Zaragoza, Spain
    • Schirmer R.H., Adler H., Zappe H.A., Gromer S., Becker K., Coulibaly B., Meissner P. Disulfide reductases as drug targets: methylene blue combination therapies for falciparum malaria in African children. Flavins and Flavoproteins 2008, 481-486. Prensas Universitarias de Zaragoza, Zaragoza, Spain.
    • (2008) Flavins and Flavoproteins , pp. 481-486
    • Schirmer, R.H.1    Adler, H.2    Zappe, H.A.3    Gromer, S.4    Becker, K.5    Coulibaly, B.6    Meissner, P.7
  • 67
    • 27544434008 scopus 로고    scopus 로고
    • Vasoplegic syndrome-the role of methylene blue
    • Shanmugam G. Vasoplegic syndrome-the role of methylene blue. Eur. J. Cardiothorac. Surg 2005, 28:705-710.
    • (2005) Eur. J. Cardiothorac. Surg , vol.28 , pp. 705-710
    • Shanmugam, G.1
  • 68
    • 60549111668 scopus 로고    scopus 로고
    • Intradermal injection of methylene blue for the treatment of refractory pruritus ani
    • Sutherland A.D., Faragher I.G., Frizelle F.A. Intradermal injection of methylene blue for the treatment of refractory pruritus ani. Colorectal Dis 2009, 11:282-287.
    • (2009) Colorectal Dis , vol.11 , pp. 282-287
    • Sutherland, A.D.1    Faragher, I.G.2    Frizelle, F.A.3
  • 70
    • 14844303721 scopus 로고    scopus 로고
    • Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins
    • Taniguchi S., Suzuki N., Masuda M., Hisanaga S., Iwatsubo T., Goedert M., Hasegawa M. Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins. J. Biol. Chem 2005, 280:7614-7623.
    • (2005) J. Biol. Chem , vol.280 , pp. 7614-7623
    • Taniguchi, S.1    Suzuki, N.2    Masuda, M.3    Hisanaga, S.4    Iwatsubo, T.5    Goedert, M.6    Hasegawa, M.7
  • 71
    • 77954954324 scopus 로고    scopus 로고
    • Methylene blue fails to inhibit Tau and polyglutamine protein dependent toxicity in zebrafish
    • van Bebber F., Paquet D., Hruscha A., Schmid B., Haass C. Methylene blue fails to inhibit Tau and polyglutamine protein dependent toxicity in zebrafish. Neurobiol. Dis 2010, 39:265-271.
    • (2010) Neurobiol. Dis , vol.39 , pp. 265-271
    • van Bebber, F.1    Paquet, D.2    Hruscha, A.3    Schmid, B.4    Haass, C.5
  • 74
    • 20444413408 scopus 로고    scopus 로고
    • The phenothiazinium chromophore and the evolution of antimalarial drugs
    • Wainwright M., Amaral L. The phenothiazinium chromophore and the evolution of antimalarial drugs. Trop. Med. Int. Health 2005, 10:501-511.
    • (2005) Trop. Med. Int. Health , vol.10 , pp. 501-511
    • Wainwright, M.1    Amaral, L.2
  • 76
    • 77952332824 scopus 로고    scopus 로고
    • Inhibition of hsp70 by methylene blue affects signaling protein function and ubiquitination and modulates polyglutamine protein degradation
    • Wang A.M., Morishima Y., Clapp K.M., Peng H.M., Pratt W.B., Gestwicki J.E., Osawa Y., Lieberman A.P. Inhibition of hsp70 by methylene blue affects signaling protein function and ubiquitination and modulates polyglutamine protein degradation. J. Biol. Chem 2010, 285:15714-15723.
    • (2010) J. Biol. Chem , vol.285 , pp. 15714-15723
    • Wang, A.M.1    Morishima, Y.2    Clapp, K.M.3    Peng, H.M.4    Pratt, W.B.5    Gestwicki, J.E.6    Osawa, Y.7    Lieberman, A.P.8
  • 78
    • 67349200953 scopus 로고    scopus 로고
    • Tau aggregation inhibitor (TAI) therapy with Rember™ arrests disease progression in mild and moderate Alzheimer's disease over 50 weeks
    • Wischik C.M., Bentham P., Wischik D.J., Seng K.M. Tau aggregation inhibitor (TAI) therapy with Rember™ arrests disease progression in mild and moderate Alzheimer's disease over 50 weeks. Alzheimers Dement 2008, 4:T167.
    • (2008) Alzheimers Dement , vol.4
    • Wischik, C.M.1    Bentham, P.2    Wischik, D.J.3    Seng, K.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.