Mitochondrial oxidative stress alters a pathway in caenorhabditis elegans strongly resembling that of bile acid biosynthesis and secretion in vertebrates

PLoS Genetics

Volumn 8, Issue 3, 2012, Pages

  Liu, Ju Ling ^a   Desjardins, David ^a   Branicky, Robyn ^a   Agellon, Luis B ^a   Hekimi, Siegfried ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; COLESTYRAMINE; SUPEROXIDE DISMUTASE; TRANSACTIVATOR PROTEIN; TRANSACTIVATOR PROTEIN 2; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATASE; ATP8B1 PROTEIN, HUMAN; CAENORHABDITIS ELEGANS PROTEIN; CHOLESTEROL; CLK 1 PROTEIN, C ELEGANS; CLK-1 PROTEIN, C ELEGANS; LIPID; LIPOPROTEIN;

ACID SECRETION; ARTICLE; BILE ACID SYNTHESIS; CAENORHABDITIS ELEGANS; CHOLESTEROL INTAKE; CONTROLLED STUDY; DEFECATION; GENE; GENE MUTATION; MITOCHONDRION; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PHENOTYPE; TAT 2 GENE; VERTEBRATE; ANIMAL; BIOSYNTHESIS; DRUG ANTAGONISM; GENE SILENCING; GENETICS; HUMAN; METABOLISM; SEQUENCE HOMOLOGY;

CAENORHABDITIS ELEGANS; MAMMALIA; VERTEBRATA;

ADENOSINE TRIPHOSPHATASES; ANIMALS; BILE ACIDS AND SALTS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CHOLESTEROL; CHOLESTYRAMINE RESIN; GENE KNOCKDOWN TECHNIQUES; HUMANS; LIPIDS; LIPOPROTEINS; MITOCHONDRIA; OXIDATIVE STRESS; SEQUENCE HOMOLOGY, AMINO ACID; SUPEROXIDE DISMUTASE;

EID: 84859242589     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002553     Document Type: Article

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