Atp8b1 deficiency in mice reduces resistance of the canalicular membrane to hydrophobic bile salts and impairs bile salt transport

Hepatology

Volumn 44, Issue 1, 2006, Pages 195-204

  Paulusma, Coen C ^a   Groen, Annemiek ^a   Kunne, Cindy ^a   Ho Mok, Kam S ^a   Spijkerboer, Astrid L ^a   Rudi De Waart, D ^a   Hoek, Frans J ^a   Vreeling, Heleen ^a   Hoeben, Kees A ^a   Van Marle, Jan ^a   Pawlikowska, Ludmila ^b   Bull, Laura N ^b   Hofmann, Alan F ^c   Knisely, A S ^d   Oude Elferink, Ronald P J ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d KING S COLLEGE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ATP8B1 ENZYME; BILE SALT; CHOLESTEROL; ECTOENZYME DERIVATIVE; LIVER ENZYME; PHOSPHATIDYLSERINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE; CONTROLLED STUDY; ENZYME DEFICIENCY; HEPATOBILIARY SYSTEM; HUMAN; HUMAN TISSUE; HYDROPHOBICITY; IMMUNOHISTOCHEMISTRY; INTRAHEPATIC BILE DUCT; INTRAHEPATIC CHOLESTASIS; MEMBRANE RESISTANCE; MEMBRANE TRANSPORT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS TYPE 1; PROTEIN EXPRESSION;

ADENOSINE TRIPHOSPHATASES; ANIMALS; BILE ACIDS AND SALTS; BILE CANALICULI; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; CELL MEMBRANE; CHOLESTASIS, INTRAHEPATIC; CHROMATOGRAPHY, THIN LAYER; DISEASE MODELS, ANIMAL; HYDROPHOBICITY; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICROSCOPY, ELECTRON;

EID: 33745906532     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.21212     Document Type: Article

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