Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats

Cardiovascular Research

Volumn 94, Issue 1, 2012, Pages 144-153

  Sun, Qiang ^a,b,c   Kawamura, Tomohiro ^a   Masutani, Kosuke ^a   Peng, Ximei ^a   Sun, Qing ^b   Stolz, Donna B ^a   Pribis, John P ^a   Billiar, Timothy R ^a   Sun, Xuejun ^b   Bermudez, Christian A ^a   Toyoda, Yoshiya ^a   Nakao, Atsunori ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c NAVAL MEDICAL RESEARCH INSTITUTE   (China)

Author keywords

Antioxidant; Hydrogen; Inflammation; Intimal hyperplasia; Vein grafting

Indexed keywords

DEGASSED WATER; DRINKING WATER; GELATINASE A; GELATINASE B; HYDROGEN RICH WATER; MAGNESIUM; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; TAP WATER; UNCLASSIFIED DRUG;

ABDOMINAL AORTA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTERY INTIMA PROLIFERATION; ARTICLE; CELL AGGREGATION; CELL INFILTRATION; CELL MIGRATION; CONTROLLED STUDY; FLUID INTAKE; IN VITRO STUDY; INFERIOR CAVA VEIN; LEUKOCYTE; MACROPHAGE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; THROMBOCYTE AGGREGATION; UPREGULATION; VEIN GRAFT;

ADMINISTRATION, ORAL; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; AORTA, ABDOMINAL; CARDIOVASCULAR AGENTS; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DRINKING; ENDOTHELIAL CELLS; ENZYME ACTIVATION; HUMANS; HYDROGEN; HYPERPLASIA; INTERLEUKIN-6; MACROPHAGES; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NEOINTIMA; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RATS; RATS, INBRED LEW; TIME FACTORS; TRANSPLANTATION, ISOGENEIC; TUMOR NECROSIS FACTOR-ALPHA; TUNICA INTIMA; VASCULAR GRAFTING; VENA CAVA, INFERIOR;

EID: 84859088927     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvs024     Document Type: Article

References (40)

1. Nguyen LL, Conte MS, Menard MT, Gravereaux EC, Chew DK, Donaldson MC et al. Infrainguinal vein bypass graft revision: factors affecting long-term outcome. J Vasc Surg 2004;40:916-923.
2. Feinglass J, Kaushik S, Handel D, Kosifas A, Martin GJ, Pearce WH. Peripheral bypass surgery and amputation: Northern illinois demographics, 1993 to 1997. Arch Surg 2000;135:75-80.
3. Lytle BW, Loop FD, Taylor PC, Simpfendorfer C, Kramer JR, Ratliff NB et al. Vein graft disease: the clinical impact of stenoses in saphenous vein bypass grafts to coronary arteries. J Thorac Cardiovasc Surg 1992;103:831-840.
4. Davies MG, Hagen PO. Pathophysiology of vein graft failure: a review. Eur J Vasc Endovasc Surg 1995;9:7-18.
5. Wallitt EJ, Jevon M, Hornick PI. Therapeutics of vein graft intimal hyperplasia: 100 years on. Ann Thorac Surg 2007;84:317-323.
6. Nakao A, Murase N, Ho C, Toyokawa H, Billiar TR, Kanno S. Biliverdin administration prevents the formation of intimal hyperplasia induced by vascular injury. Circulation 2005;112:587-591.
7. Nigri GR, Kossodo S, Waterman P, Fungaloi P, LaMuraglia GM. Free radical attenuation prevents thrombosis and enables photochemical inhibition of vein graft intimal hyperplasia. J Vasc Surg 2004;39:843-849.
8. Rosenbaum MA, Miyazaki K, Colles SM, Graham LM. Antioxidant therapy reverses impaired graft healing in hypercholesterolemic rabbits. J Vasc Surg 2010;51:184-193.
9. Liu SQ, Ruan YY, Tang D, Li YC, Goldman J, Zhong L. A possible role of initial cell death due to mechanical stretch in the regulation of subsequent cell proliferation in experimental vein grafts. Biomech Model Mechanobiol 2002;1:17-27.
10. Davies MG, Dalen H, Barber L, Svendsen E, Hagen PO. Lazaroid therapy (methylaminochroman: U83836e) reduces vein graft intimal hyperplasia. J Surg Res 1996;63: 128-136.
11. Joddar B, Reen RK, Firstenberg MS, Varadharaj S, McCord JM, Zweier JL et al. Protandim attenuates intimal hyperplasia in human saphenous veins cultured ex vivo via a catalase-dependent pathway. Free Radic Biol Med 2011;50:700-709.
12. Huang CS, Kawamura T, Toyoda Y, Nakao A. Recent advances in hydrogen research as a therapeutic medical gas. Free Radic Res 2010;44:971-982.
13. Ohsawa I, Ishikawa M, Takahashi K, Watanabe M, Nishimaki K, Yamagata K et al. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med 2007;13:688-694.
14. Kajiya M, Silva MJ, Sato K, Ouhara K, Kawai T. Hydrogen mediates suppression of colon inflammation induced by dextran sodium sulfate. Biochem Biophys Res Commun 2009;386:11-15.
15. Fujita K, Seike T, Yutsudo N, Ohno M, Yamada H, Yamaguchi H et al. Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of parkinson's disease. PLoS One 2009;4:e7247.
16. Abraini JH, Gardette-Chauffour MC, Martinez E, Rostain JC, Lemaire C. Psychophysiological reactions in humans during an open sea dive to 500 m with a hydrogen-helium-oxygen mixture. J Appl Physiol 1994;76:1113-1118.
17. Cardinal JS, Zhan J, Wang Y, Sugimoto R, Tsung A, McCurry KR et al. Oral hydrogen water prevents chronic allograft nephropathy in rats. Kidney Int 2010;77:101-109.
18. Kamimura N, Nishimaki K, Ohsawa I, Ohta S. Molecular hydrogen improves obesity and diabetes by inducing hepatic fgf21 and stimulating energy metabolism in db/db mice. Obesity 2011;19:1396-1403.
19. Nakao A, Toyoda Y, Sharma P, Evans M, Guthrie N. Effectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome-an open label pilot study. J Clin Biochem Nutr 2010;46:140-149.
20. Kajiyama S, Hasegawa G, Asano M, Hosoda H, Fukui M, Nakamura N et al. Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance. Nutr Res 2008;28:137-143.
21. Nakao A, Huang CS, Stolz DB, Wang Y, Franks JM, Tochigi N et al. Ex vivo carbon monoxide delivery inhibits intimal hyperplasia in arterialized vein grafts. Cardiovasc Res 2010;89:457-463.
22. Buchholz BM, Kaczorowski DJ, Sugimoto R, Yang R, Wang Y, Billiar TR et al. Hydrogen inhalation ameliorates oxidative stress in transplantation induced intestinal graft injury. Am J Transplant 2008;8:2015-2024.
23. Sun H, Valdivia LA, Subbotin V, Aitouche A, Fung JJ, Starzl TE et al. Improved surgical technique for the establishment of a murine model of aortic transplantation. Microsurgery 1998;18:368-371.
24. Cheng ST, Chen ZF, Chen GQ. The expression of cross-linked elastin by rabbit blood vessel smooth muscle cells cultured in polyhydroxyalkanoate scaffolds. Biomaterials 2008;29:4187-4194.
25. Wei Y, Chen L, Chen J, Ge L, He RQ. Rapid glycation with d-ribose induces globular amyloid-like aggregations of BSA with high cytotoxicity to sh-sy5y cells. BMC Cell Biol 2009;10:10.
26. Berceli SA, Jiang Z, Klingman NV, Pfahnl CL, Abouhamze ZS, Frase CD et al. Differential expression and activity of matrix metalloproteinases during flow-modulated vein graft remodeling. J Vasc Surg 2004;39:1084-1090.
27. Thomas AC, Newby AC. Effect of matrix metalloproteinase-9 knockout on vein graft remodelling in mice. J Vasc Res 2010;47:299-308.
28. Zhang WD, Bai HZ, Sawa Y, Yamakawa T, Kadoba K, Taniguchi K et al. Association of smooth muscle cell phenotypic modulation with extracellular matrix alterations during neointima formation in rabbit vein grafts. J Vasc Surg 1999;30:169-183.
29. Ohsawa I, Nishimaki K, Yamagata K, Ishikawa M, Ohta S. Consumption of hydrogen water prevents atherosclerosis in apolipoprotein e knockout mice. Biochem Biophys Res Commun 2008;377:1195-1198.
30. Itoh T, Fujita Y, Ito M, Masuda A, Ohno K, Ichihara M et al. Molecular hydrogen suppresses fcepsilonri-mediated signal transduction and prevents degranulation of mast cells. Biochem Biophys Res Commun 2009;389:651-656.
31. Kawamura T, Huang CS, Tochigi N, Lee S, Shigemura N, Billiar TR et al. Inhaled hydrogen gas therapy for prevention of lung transplant-induced ischemia/reperfusion injury in rats. Transplantation 2010;90:1344-1351.
32. Huang CS, Kawamura T, Peng X, Tochigi N, Shigemura N, Billiar TR et al. Hydrogen inhalation reduced epithelial apoptosis in ventilator-induced lung injury via a mechanism involving nuclear factor-kappa b activation. Biochem Biophys Res Commun 2011; 408:253-258.
33. Buchholz BM, Masutani K, Kawamura T, Peng X, Toyoda Y, Billiar TR et al. Hydrogen-enriched preservation protects the isogeneic intestinal graft and amends recipient gastric function during transplantation. Transplantation 2011;92:985-992.
34. Ono K, Han J. The p38 signal transduction pathway: activation and function. Cell Signal 2000;12:1-13.
35. Jiang Z, Shukla A, Miller BL, Espino DR, Tao M, Berceli SA et al. Tumor necrosis factor-alpha and the early vein graft. J Vasc Surg 2007;45:169-176.
36. Chello M, Mastroroberto P, Frati G, Patti G, D'Ambrosio A, Di Sciascio G et al. Pressure distension stimulates the expression of endothelial adhesion molecules in the human saphenous vein graft. Ann Thorac Surg 2003;76:453-458.
37. Anggrahini DW, Emoto N, Nakayama K, Widyantoro B, Adiarto S, Iwasa N et al. Vascular endothelial cell-derived endothelin-1 mediates vascular inflammation and neointima formation following blood flow cessation. Cardiovasc Res 2009;82:143-151.
38. Sharony R, Pintucci G, Saunders PC, Grossi EA, Baumann FG, Galloway AC et al. Matrix metalloproteinase expression in vein grafts: role of inflammatory mediators and extracellular signal-regulated kinases-1 and -2. Am J Physiol Heart Circ Physiol 2006;290:H1651-H1659.
39. Woo MS, Jung SH, Kim SY, Hyun JW, Ko KH, Kim WK et al. Curcumin suppresses phorbol ester-induced matrix metalloproteinase-9 expression by inhibiting the PKC to MAPK signaling pathways in human astroglioma cells. Biochem Biophys Res Commun 2005;335:1017-1025.
40. Chien ST, Lin SS, Wang CK, Lee YB, Chen KS, Fong Y et al. Acacetin inhibits the invasion and migration of human non-small cell lung cancer a549 cells by suppressing the p38alpha mapk signaling pathway. Mol Cell Biochem 2011;350:135-148.