Protandim attenuates intimal hyperplasia in human saphenous veins cultured ex vivo via a catalase-dependent pathway

Free Radical Biology and Medicine

Volumn 50, Issue 6, 2011, Pages 700-709

  Joddar, Binata ^a,b,c   Reen, Rashmeet K ^b,d   Firstenberg, Michael S ^d   Varadharaj, Saradhadevi ^b   McCord, Joe M ^e   Zweier, Jay L ^b   Gooch, Keith J ^a,b  

^a Ohio State University   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c RIKEN   (Japan)

^d OHIO STATE UNIVERSITY   (United States)

^e UNIVERSITY OF COLORADO   (United States)

Author keywords

Catalase; Ex vivo culture; Free radicals; Human saphenous veins; Protandim; Scavenging enzymes

Indexed keywords

AMITROLE; ANTIOXIDANT; CATALASE; ENZYME; HERBACEOUS AGENT; PROTANDIM; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ARTERY INTIMA PROLIFERATION; ARTICLE; CELL ISOLATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INDUCTION; ENZYME INHIBITION; EX VIVO STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; SAPHENOUS VEIN; SIGNAL TRANSDUCTION; VEIN GRAFT DISEASE;

AMITROLE; ANTIOXIDANTS; BLOTTING, WESTERN; CATALASE; CELL PROLIFERATION; DRUGS, CHINESE HERBAL; ENDOTHELIUM, VASCULAR; FLUORESCENT ANTIBODY TECHNIQUE; HEME OXYGENASE-1; HUMANS; HYPERPLASIA; ORGAN CULTURE TECHNIQUES; REACTIVE OXYGEN SPECIES; SAPHENOUS VEIN; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; SUPEROXIDES; TUNICA INTIMA; UP-REGULATION;

SIMPLEXVIRUS;

EID: 79951675827     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2010.12.008     Document Type: Article

References (50)

1. J.G. Motwani, and E.J. Topol Aortocoronary saphenous vein graft disease: pathogenesis, predisposition, and prevention Circulation 97 1998 916 931 (Pubitemid 28113931)
2. S. Muhammad Anees N-acetylcysteine does not improve the endothelial and smooth muscle function in the human saphenous vein Vasc. Endovasc. Surg. 41 2007 239 245
3. S. Goldman Improvement in early saphenous vein graft patency after coronary artery bypass surgery with antiplatelet therapy: results of a Veterans Administration cooperative study Circulation 77 1988 1324 1332
4. S. Goldman Saphenous vein graft patency 1 year after coronary artery bypass surgery and effects of antiplatelet therapy: results of a Veterans Administration cooperative study Circulation 80 1989 1190 1197 (Pubitemid 19282507)
5. D.T. Mangano Aspirin and mortality from coronary bypass surgery N. Engl. J. Med. 347 2002 1309 1317 (Pubitemid 35215321)
6. K.E. Porter, and N.A. Turner Statins for the prevention of vein graft stenosis: a role for inhibition of matrix metalloproteinase-9 Biochem. Soc. Trans. 30 2002 120 126
7. A. Briasoulis The oxidative stress menace to coronary vasculature: any place for antioxidants? Curr. Pharm. Des. 15 2009 3078 3090
8. J.M. Onorato, S.R. Thorpe, and J.W. Baynes Immunohistochemical and ELISA assays for biomarkers of oxidative stress in aging and disease Ann. N. Y. Acad. Sci. 854 1998 277 290 (Pubitemid 29022809)
9. G.D. Mark Lazaroid therapy (methylaminochroman: U83836E) reduces vein graft intimal hyperplasia J. Surg. Res. 63 1996 128 136
10. T.T.H. Tam Reduction of lipid peroxidation with intraoperative superoxide dismutase treatment decreases intimal hyperplasia in experimental vein grafts J. Surg. Res. 84 1999 223 232
11. M. Paolini Antioxidant vitamins for prevention of cardiovascular disease Lancet 362 2003 920-920
12. C. Antoniades Oxidative stress, antioxidant vitamins, and atherosclerosis Herz 28 2003 628 638
13. P. Jha The antioxidant vitamins and cardiovascular disease: a critical review of epidemiologic and clinical trial data Ann. Intern. Med. 123 1995 860 872
14. W.A. Pryor Vitamin E and heart disease: basic science to clinical intervention trials Free Radic. Biol. Med. 28 2000 141 164 (Pubitemid 30045582)
15. A. Carr, and B. Frei Does vitamin C act as a pro-oxidant under physiological conditions? FASEB J. 13 1999 1007 1024 (Pubitemid 29249726)
16. J.C. Tardif Pharmacologic prevention of both restenosis and atherosclerosis progression: AGI-1067, probucol, statins, folic acid and other therapies Curr. Opin. Lipidol. 14 2003 615 620
17. J.C. Tardif Clinical results with AGI-1067: a novel antioxidant vascular protectant Am. J. Cardiol. 91 2003 41A 49A
18. J.C. Tardif Effects of AGI-1067 and probucol after percutaneous coronary interventions Circulation 107 2003 552 558
19. J.C. Tardif Effects of the antioxidant succinobucol (AGI-1067) on human atherosclerosis in a randomized clinical trial Atherosclerosis 197 2008 480 486
20. S.K. Nelson The induction of human superoxide dismutase and catalase in vivo: a fundamentally new approach to antioxidant therapy Free Radic. Biol. Med. 40 2006 341 347 (Pubitemid 43069358)
21. J. Liu Protandim, a fundamentally new antioxidant approach in chemoprevention using mouse two-stage skin carcinogenesis as a model PLoS ONE 4 2009 e5284
22. K. Velmurugan Synergistic induction of heme oxygenase-1 by the components of the antioxidant supplement Protandim Free Radic. Biol. Med. 46 2009 430 440
23. K.E. Porter The development of an in vitro flow model of human saphenous vein graft intimal hyperplasia Cardiovasc. Res. 31 1996 607 614 (Pubitemid 26140066)
24. K.E. Porter Human saphenous vein organ culture: a useful model of intimal hyperplasia? Eur. J. Vasc. Endovasc. Surg. 11 1996 48 58 (Pubitemid 26120450)
25. T. Schachner Pharmacologic inhibition of vein graft neointimal hyperplasia J. Thorac. Cardiovasc. Surg. 131 2006 1065 1072
26. A.A. Soyombo Intimal proliferation in an organ culture of human saphenous vein Am. J. Pathol. 137 1990 1401 1410
27. A. Mekontso-Dessap Vascular-wall remodeling of 3 human bypass vessels: organ culture and smooth muscle cell properties J. Thorac. Cardiovasc. Surg. 131 2006 651 658
28. R.J. Gusic Shear stress and pressure modulate saphenous vein remodeling ex vivo J. Biomech. 38 2005 1760 1769 (Pubitemid 40967951)
29. R.J. Gusic Mechanical properties of native and ex vivo remodeled porcine saphenous veins J. Biomech. 38 2005 1770 1779 (Pubitemid 40967952)
30. J.F. Keaney Jr. Low-dose alpha-tocopherol improves and high-dose alpha-tocopherol worsens endothelial vasodilator function in cholesterol-fed rabbits J. Clin. Invest. 93 1994 844 851 (Pubitemid 24072828)
31. S. Yusuf Vitamin E supplementation and cardiovascular events in high-risk patients: the Heart Outcomes Prevention Evaluation Study Investigators N. Engl. J. Med. 342 2000 154 160 (Pubitemid 30051646)
32. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial Lancet 354 1999 447 455
33. N.G. Stephens Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS) Lancet 347 1996 781 786 (Pubitemid 26091640)
34. J.C. Tardif Antioxidants: the good, the bad and the ugly Can. J. Cardiol. 22 Suppl. B 2006 61B 65B
35. B. Joddar Role of oxygen tension and oxidative stress in human saphenous vein remodeling Circulation 118 18th meeting abstracts 2008 S1017-a [Abstract 5858]
36. 2 stimulates intimal hyperplasia and serum stimulates inward eutrophic remodeling in porcine saphenous veins cultured ex vivo Biomech. Model. Mechanobiol 2010 May 30 [Electronic publication ahead of print]
37. M. Zanetti Analysis of superoxide anion production in tissue Methods Mol. Med. 108 2005 65 72
38. M. Galinanes PEG-SOD and myocardial protection: studies in the blood- and crystalloid-perfused rabbit and rat hearts Circulation 86 1992 672 682
39. N.G.N. Milton Inhibition of catalase activity with 3-amino-triazole enhances the cytotoxicity of the Alzheimer's amyloid-β peptide NeuroToxicology 22 2001 767 774 (Pubitemid 34075634)
40. H.J. Martin, and E. Maser Role of human aldo-keto-reductase AKR1B10 in the protection against toxic aldehydes Chem. Biol. Interact. 178 2009 145 150
41. L. Zhong Aldo-keto reductase family 1 B10 protein detoxifies dietary and lipid-derived α,β-unsaturated carbonyls at physiological levels Biochem. Biophys. Res. Commun. 387 2009 245 250
42. G. Leonarduzzi, F. Robbesyn, and G. Poli Signaling kinases modulated by 4-hydroxynonenal Free Radic. Biol. Med. 37 2004 1694 1702 (Pubitemid 39445371)
43. G. Poli 4-Hydroxynonenal: a membrane lipid oxidation product of medicinal interest Med. Res. Rev. 28 2008 569 631 (Pubitemid 351842143)
44. A. Bast, G.R. Haenen, and C.J. Doelman Oxidants and antioxidants: state of the art Am. J. Med. 91 1991 2S 13S
45. - elevated by oxidized LDL enhances human aortic smooth muscle cell proliferation J. Biomed. Sci. 14 2007 245 254
46. 2 Hypertension 46 2005 732 737 (Pubitemid 43186746)
47. E. Margoliash, A. Novogrodsky, and A. Schejter Irreversible reaction of 3-amino-1:2:4-triazole and related inhibitors with the protein of catalase Biochem. J. 74 1960 339
48. H. Yang Retardation of atherosclerosis by overexpression of catalase or both Cu/Zn-superoxide dismutase and catalase in mice lacking apolipoprotein E Circ. Res. 95 2004 1075 1081 (Pubitemid 39557894)
49. P.B. Dobrin, F.N. Littooy, and E.D. Endean Mechanical factors predisposing to intimal hyperplasia and medial thickening in autogenous vein grafts Surgery 105 1989 393 400 (Pubitemid 19076428)
50. G. Konig Mechanical properties of completely autologous human tissue engineered blood vessels compared to human saphenous vein and mammary artery Biomaterials 30 2009 1542 1550