The G protein-coupled receptor CysLT1 mediates chemokine-like effects and prolongs survival in chronic lymphocytic leukemia

Leukemia and Lymphoma

Volumn 53, Issue 4, 2012, Pages 665-673

  Drost, Adriana C ^a   Seitz, Gabriele ^a   Boehmler, Andreas ^a,b   Funk, Mirjam ^a   Norz, Karoline Pia ^a   Zipfel, Anne ^a   Xue, Xingkui ^a,c   Kanz, Lothar ^a   Möhle, Robert ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b BECKMAN COULTER INC   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CLL; CysLT1; CysLT2; Migration; Survival

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; G PROTEIN COUPLED RECEPTOR; LEUKOTRIENE D4; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PEPTIDOLEUKOTRIENE; PERTUSSIS TOXIN;

ACTIN POLYMERIZATION; AGED; APOPTOSIS; ARTICLE; B LYMPHOCYTE; BONE MARROW; CALCIUM TRANSPORT; CHEMOTAXIS; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SURVIVAL;

ACETOPHENONES; ACTINS; AGED; APOPTOSIS; BLOTTING, WESTERN; CALCIUM; CELL LINE, TUMOR; CELL SURVIVAL; CHEMOKINES; CHEMOTAXIS; CYSTEINE; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; JURKAT CELLS; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; LEUKOTRIENE ANTAGONISTS; LEUKOTRIENE D4; LEUKOTRIENES; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROPIONATES; QUINOLINES; RECEPTORS, LEUKOTRIENE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TETRAZOLES; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 84859011709     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2011.625578     Document Type: Article

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