Novel enzymatic abnormalities in AML and CML in blast crisis: Elevated leucocyte leukotriene C4 synthase activity paralleled by deficient leukotriene biosynthesis from endogenous substrate

British Journal of Haematology

Volumn 101, Issue 4, 1998, Pages 728-736

  Stenke, Leif ^a   Sjölinder, Mikael ^a   Miale, Thomas D ^a   Lindgren, Jan Åke ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

5 lipoxygenase activity; Acute myeloid leukaemia; Chronic myeloid leukaemia in blast crisis; Leukotrienes; LTC4 synthase

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONIC ACID; CALCIMYCIN; LEUKOTRIENE B4; LEUKOTRIENE C4; LEUKOTRIENE C4 SYNTHASE; SYNTHETASE; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; ARTICLE; BIOSYNTHESIS; BLAST CELL CRISIS; CHRONIC MYELOID LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBSTRATE; FEMALE; HUMAN; HUMAN CELL; LEUKOCYTE DIFFERENTIAL COUNT; MALE; PRIORITY JOURNAL;

ACUTE DISEASE; ADOLESCENT; ADULT; AGED; BLAST CRISIS; FEMALE; GLUTATHIONE TRANSFERASE; GRANULOCYTES; HUMANS; LEUKEMIA, MYELOID; LEUKEMIA, MYELOID, CHRONIC; LEUKOCYTES; LEUKOTRIENE A4; LEUKOTRIENE C4; LEUKOTRIENES; MALE; MIDDLE AGED; TUMOR CELLS, CULTURED;

EID: 0031860067     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1998.00752.x     Document Type: Article

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