메뉴 건너뛰기




Volumn 26, Issue 2, 2012, Pages 88-102

Emerging role of innate immunity in organ transplantation part III: The quest for transplant tolerance via prevention of oxidative allograft injury and its consequences

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; ECULIZUMAB; ETANERCEPT; HEME OXYGENASE 1; IMISOPASEM MANGANESE; INFLAMMASOME; INFLIXIMAB; INTERLEUKIN 1BETA; M 40401; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; METHYLPREDNISOLONE; NORPHENAZONE; PATTERN RECOGNITION RECEPTOR; PEXELIZUMAB; ROTENONE; UNCLASSIFIED DRUG;

EID: 84859002866     PISSN: 0955470X     EISSN: 15579816     Source Type: Journal    
DOI: 10.1016/j.trre.2011.07.001     Document Type: Review
Times cited : (25)

References (88)
  • 1
    • 84859003860 scopus 로고    scopus 로고
    • Emerging role of innate immunity in organ transplantation. Part I: evolution of innate immunity and oxidative Allograft injury
    • (in press)
    • Land W.G. Emerging role of innate immunity in organ transplantation. Part I: evolution of innate immunity and oxidative Allograft injury. Transplant Rev 2011, (in press).
    • (2011) Transplant Rev
    • Land, W.G.1
  • 2
    • 84858998655 scopus 로고    scopus 로고
    • Emerging role of innate immunity in organ transplantation. Part II: potential of DAMPs to generate immunostimulatory dendritic cells
    • (in press)
    • Land W.G. Emerging role of innate immunity in organ transplantation. Part II: potential of DAMPs to generate immunostimulatory dendritic cells. Transplant Rev 2011, (in press).
    • (2011) Transplant Rev
    • Land, W.G.1
  • 5
    • 34547152610 scopus 로고    scopus 로고
    • Tolerogenic dendritic cells and the quest for transplant tolerance
    • Morelli A.E., Thomson A.W. Tolerogenic dendritic cells and the quest for transplant tolerance. Nat Rev Immunol 2007, 7:610-621.
    • (2007) Nat Rev Immunol , vol.7 , pp. 610-621
    • Morelli, A.E.1    Thomson, A.W.2
  • 6
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cell and the control of immunity
    • Bancherau J., Steinman R.M. Dendritic cell and the control of immunity. Nature 1998, 392:245-252.
    • (1998) Nature , vol.392 , pp. 245-252
    • Bancherau, J.1    Steinman, R.M.2
  • 7
    • 0035903326 scopus 로고    scopus 로고
    • Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo
    • Hawiger D., Inaba K., Dorsett Y., Guo M., Mahnke K., Rivera M., et al. Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J Exp Med 2001, 194:769-779.
    • (2001) J Exp Med , vol.194 , pp. 769-779
    • Hawiger, D.1    Inaba, K.2    Dorsett, Y.3    Guo, M.4    Mahnke, K.5    Rivera, M.6
  • 8
    • 0036378101 scopus 로고    scopus 로고
    • Immature, but not inactive: the tolerogenic function of immature dendritic cells
    • Mahnke K., Schmitt E., Bonifaz L., Enk A.H., Jonuleit H. Immature, but not inactive: the tolerogenic function of immature dendritic cells. Immunol Cell Biol 2002, 80:477-483.
    • (2002) Immunol Cell Biol , vol.80 , pp. 477-483
    • Mahnke, K.1    Schmitt, E.2    Bonifaz, L.3    Enk, A.H.4    Jonuleit, H.5
  • 9
    • 0042512461 scopus 로고    scopus 로고
    • Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells
    • Yamazaki S., Iyoda T., Tarbell K., Olson K., Velinzon K., Inaba K., Steinman R.M. Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells. J Exp Med 2003, 198:235-247.
    • (2003) J Exp Med , vol.198 , pp. 235-247
    • Yamazaki, S.1    Iyoda, T.2    Tarbell, K.3    Olson, K.4    Velinzon, K.5    Inaba, K.6    Steinman, R.M.7
  • 10
    • 39549099367 scopus 로고    scopus 로고
    • Dendritic cells are specialized accessory cells along with TGF-β for the differentiatiosn of Foxp3+CD4+ regulatory T cells from peripheral Foxp3 precursors
    • Yamazaki S., Bonito A.J., Spisek R., Dhodapkar M., Inaba K., Steinman R.M. Dendritic cells are specialized accessory cells along with TGF-β for the differentiatiosn of Foxp3+CD4+ regulatory T cells from peripheral Foxp3 precursors. Blood 2007, 110:4293-4302.
    • (2007) Blood , vol.110 , pp. 4293-4302
    • Yamazaki, S.1    Bonito, A.J.2    Spisek, R.3    Dhodapkar, M.4    Inaba, K.5    Steinman, R.M.6
  • 11
    • 78149277909 scopus 로고    scopus 로고
    • How tolerogenic dendritic cells induce regulatory T cells
    • Maldonado R.A., von Andrian U.H. How tolerogenic dendritic cells induce regulatory T cells. Adv Immunol 2010, 108:111-165.
    • (2010) Adv Immunol , vol.108 , pp. 111-165
    • Maldonado, R.A.1    von Andrian, U.H.2
  • 12
    • 2442425262 scopus 로고    scopus 로고
    • Induction of foxP3 regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants
    • Cobbold S.P., Castejon R., Adams E., Zelenika D., Graca L., Humm S., Waldmann H. Induction of foxP3 regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants. J Immunol 2004, 172:6003-6010.
    • (2004) J Immunol , vol.172 , pp. 6003-6010
    • Cobbold, S.P.1    Castejon, R.2    Adams, E.3    Zelenika, D.4    Graca, L.5    Humm, S.6    Waldmann, H.7
  • 13
    • 33744479421 scopus 로고    scopus 로고
    • Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts
    • Ochando J.C., Homma C., Yang Y., Hidalgo A., Garin A., Tacke F., et al. Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts. Nat Immunol 2006, 7:652-662.
    • (2006) Nat Immunol , vol.7 , pp. 652-662
    • Ochando, J.C.1    Homma, C.2    Yang, Y.3    Hidalgo, A.4    Garin, A.5    Tacke, F.6
  • 14
    • 78649411375 scopus 로고    scopus 로고
    • Immunoregulation and tolerance
    • Knechtle S.J. Immunoregulation and tolerance. Transplant Proc 2010, 42:S13-S15.
    • (2010) Transplant Proc , vol.42
    • Knechtle, S.J.1
  • 15
    • 78650835204 scopus 로고    scopus 로고
    • Ex vivo-expanded human regulatory T cells prevent the rejection of skin allografts in a humanized Mouse model
    • Issa F., Hester J., Goto R., Nadig S.N., Goodacre T.E., Wood K. Ex vivo-expanded human regulatory T cells prevent the rejection of skin allografts in a humanized Mouse model. Transplantation 2010, 90:1321-1327.
    • (2010) Transplantation , vol.90 , pp. 1321-1327
    • Issa, F.1    Hester, J.2    Goto, R.3    Nadig, S.N.4    Goodacre, T.E.5    Wood, K.6
  • 16
    • 77954539326 scopus 로고    scopus 로고
    • In vivo prevention of transplant arteriosclerosis by ex vivo-expanded human regulatory T cells
    • Nadig S.N., Wieckiewicz J., Wu D.C., Warnecke G., Zhang W., Luo S., et al. In vivo prevention of transplant arteriosclerosis by ex vivo-expanded human regulatory T cells. Nat Med 2010, 16:809-813.
    • (2010) Nat Med , vol.16 , pp. 809-813
    • Nadig, S.N.1    Wieckiewicz, J.2    Wu, D.C.3    Warnecke, G.4    Zhang, W.5    Luo, S.6
  • 17
    • 79952438607 scopus 로고    scopus 로고
    • Harnessing dendritic cells for immunotherapy
    • Delamarre L., Mellman I. Harnessing dendritic cells for immunotherapy. Semin Immunol 2011, 23:2-11.
    • (2011) Semin Immunol , vol.23 , pp. 2-11
    • Delamarre, L.1    Mellman, I.2
  • 19
    • 77949425125 scopus 로고    scopus 로고
    • Generation of tolerogenic dendritic cells via the E-cadherin/β-catenin-signaling pathway
    • Fu C., Jiang A. Generation of tolerogenic dendritic cells via the E-cadherin/β-catenin-signaling pathway. Immunol Res 2010, 46:72-78.
    • (2010) Immunol Res , vol.46 , pp. 72-78
    • Fu, C.1    Jiang, A.2
  • 20
    • 77955634800 scopus 로고    scopus 로고
    • Activation of beta-catenin in dendritic cells regulates immunity versus tolerance in the intestine
    • Manicassamy S., Reizis B., Ravindran R., Nakaya H., Salazar-Gonzalez R.M., Wang Y.C., et al. Activation of beta-catenin in dendritic cells regulates immunity versus tolerance in the intestine. Science 2010, 329:849-853.
    • (2010) Science , vol.329 , pp. 849-853
    • Manicassamy, S.1    Reizis, B.2    Ravindran, R.3    Nakaya, H.4    Salazar-Gonzalez, R.M.5    Wang, Y.C.6
  • 21
    • 77955646507 scopus 로고    scopus 로고
    • Immunology. Beta-catenin balances immunity
    • Mellman I., Clausen B.E. Immunology. Beta-catenin balances immunity. Science 2010, 329:767-769.
    • (2010) Science , vol.329 , pp. 767-769
    • Mellman, I.1    Clausen, B.E.2
  • 22
    • 78851471170 scopus 로고    scopus 로고
    • Dendritic cell-restricted CD80/86 deficiency results in peripheral regulatory T-cell reduction but is not associated with lymphocyte hyperactivation
    • Bar-On L., Birnberg T., Kim K.W., Jung S. Dendritic cell-restricted CD80/86 deficiency results in peripheral regulatory T-cell reduction but is not associated with lymphocyte hyperactivation. Eur J Immunol 2011, 41:291-298.
    • (2011) Eur J Immunol , vol.41 , pp. 291-298
    • Bar-On, L.1    Birnberg, T.2    Kim, K.W.3    Jung, S.4
  • 23
    • 0037122011 scopus 로고    scopus 로고
    • Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance
    • Bonifaz L., Bonnyay D., Mahnke K., Rivera M., Nussenzweig M.C., Steinman R.M. Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance. J Exp Med 2002, 196:1627-1638.
    • (2002) J Exp Med , vol.196 , pp. 1627-1638
    • Bonifaz, L.1    Bonnyay, D.2    Mahnke, K.3    Rivera, M.4    Nussenzweig, M.C.5    Steinman, R.M.6
  • 24
    • 2942523789 scopus 로고    scopus 로고
    • Immunological unresponsiveness characterized by increased expression of CD5 on peripheral T cells induced by dendritic cells in vivo
    • Hawiger D., Masilamani R.F., Bettelli E., Kuchroo V.K., Nussenzweig M.C. Immunological unresponsiveness characterized by increased expression of CD5 on peripheral T cells induced by dendritic cells in vivo. Immunity 2004, 20:695-705.
    • (2004) Immunity , vol.20 , pp. 695-705
    • Hawiger, D.1    Masilamani, R.F.2    Bettelli, E.3    Kuchroo, V.K.4    Nussenzweig, M.C.5
  • 25
    • 0037364804 scopus 로고    scopus 로고
    • Natural versus adaptive regulatory T cells
    • Bluestone J., Abbas A. Natural versus adaptive regulatory T cells. Nat Rev Immunol 2003, 3:253-257.
    • (2003) Nat Rev Immunol , vol.3 , pp. 253-257
    • Bluestone, J.1    Abbas, A.2
  • 27
    • 39449126502 scopus 로고    scopus 로고
    • The Foxp3+ regulatory T cell: a jack of all trades, master of regulation
    • Tang Q., Bluestone J.A. The Foxp3+ regulatory T cell: a jack of all trades, master of regulation. Nat Immunol 2008, 9:239-244.
    • (2008) Nat Immunol , vol.9 , pp. 239-244
    • Tang, Q.1    Bluestone, J.A.2
  • 29
    • 77953374425 scopus 로고    scopus 로고
    • Mechanisms of self-nonself discrimination and possible clinical relevance
    • Daniel C., Nolting J., von Boehmer H. Mechanisms of self-nonself discrimination and possible clinical relevance. Immunotherapy 2009, 1:631-644.
    • (2009) Immunotherapy , vol.1 , pp. 631-644
    • Daniel, C.1    Nolting, J.2    von Boehmer, H.3
  • 30
    • 78049303465 scopus 로고    scopus 로고
    • Infectious tolerance: therapeutic potential
    • Kendal A.R., Waldmann H. Infectious tolerance: therapeutic potential. Curr Opin Immunol 2010, 22:560-565.
    • (2010) Curr Opin Immunol , vol.22 , pp. 560-565
    • Kendal, A.R.1    Waldmann, H.2
  • 31
    • 3242754344 scopus 로고    scopus 로고
    • Tolerance induced by inhaled antigen involves CD4(+) T cells expressing membrane-bound TGF-beta and FOXP3
    • Ostroukhova M., Seguin-Devaux C., Oriss T.B., Dixon-McCarthy B., Yang L., Ameredes B.T., et al. Tolerance induced by inhaled antigen involves CD4(+) T cells expressing membrane-bound TGF-beta and FOXP3. J Clin Invest 2004, 114:28-38.
    • (2004) J Clin Invest , vol.114 , pp. 28-38
    • Ostroukhova, M.1    Seguin-Devaux, C.2    Oriss, T.B.3    Dixon-McCarthy, B.4    Yang, L.5    Ameredes, B.T.6
  • 32
    • 2542420993 scopus 로고    scopus 로고
    • In vivo instruction of suppressor commitment in naive T cells
    • Apostolou I., von Boehmer H. In vivo instruction of suppressor commitment in naive T cells. J Exp Med 2004, 199:1401-1408.
    • (2004) J Exp Med , vol.199 , pp. 1401-1408
    • Apostolou, I.1    von Boehmer, H.2
  • 33
    • 3142720367 scopus 로고    scopus 로고
    • Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen
    • de Heer H.J., Hammad H., Soullie' T., Hijdra D., Vos N., Willart M.A.M., et al. Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen. J Exp Med 2004, 200:89-98.
    • (2004) J Exp Med , vol.200 , pp. 89-98
    • de Heer, H.J.1    Hammad, H.2    Soullie', T.3    Hijdra, D.4    Vos, N.5    Willart, M.A.M.6
  • 35
    • 53849125398 scopus 로고    scopus 로고
    • Oral tolerance: intestinal homeostasis and antigen-specific regulatory T cells
    • Tsuji N.M., Kosaka A. Oral tolerance: intestinal homeostasis and antigen-specific regulatory T cells. Trends Immunol 2008, 29:532-540.
    • (2008) Trends Immunol , vol.29 , pp. 532-540
    • Tsuji, N.M.1    Kosaka, A.2
  • 36
    • 70049101757 scopus 로고    scopus 로고
    • Biology of lung dendritic cells at the origin of asthma
    • Lambrecht B.N., Hammad H. Biology of lung dendritic cells at the origin of asthma. Immunity 2009, 31:412-424.
    • (2009) Immunity , vol.31 , pp. 412-424
    • Lambrecht, B.N.1    Hammad, H.2
  • 37
    • 0032211803 scopus 로고    scopus 로고
    • GM-CSF transgene expression in the airway allows aerosolized ovalbumin to induce allergic sensitization in mice
    • Stampfli M.R., Wiley R.E., Neigh G.S., Gajewska B.U., Lei X.F., Snider D.P., et al. GM-CSF transgene expression in the airway allows aerosolized ovalbumin to induce allergic sensitization in mice. J Clin Invest 1998, 102:1704-1714.
    • (1998) J Clin Invest , vol.102 , pp. 1704-1714
    • Stampfli, M.R.1    Wiley, R.E.2    Neigh, G.S.3    Gajewska, B.U.4    Lei, X.F.5    Snider, D.P.6
  • 38
    • 0037121946 scopus 로고    scopus 로고
    • Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen
    • Eisenbarth S.C., Piggott D.A., Huleatt J.W., Visintin I., Herrick C.A., Bottomly K. Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J Exp Med 2002, 196:1645-1651.
    • (2002) J Exp Med , vol.196 , pp. 1645-1651
    • Eisenbarth, S.C.1    Piggott, D.A.2    Huleatt, J.W.3    Visintin, I.4    Herrick, C.A.5    Bottomly, K.6
  • 39
    • 34548751712 scopus 로고    scopus 로고
    • De novo production of antigen-specific suppressor cells in vivo
    • Kretschmer K., Heng T.S., von Boehmer H. De novo production of antigen-specific suppressor cells in vivo. Nat Protoc 2006, 1:653-661.
    • (2006) Nat Protoc , vol.1 , pp. 653-661
    • Kretschmer, K.1    Heng, T.S.2    von Boehmer, H.3
  • 41
    • 2342652841 scopus 로고    scopus 로고
    • Transplantation tolerance induced by intranasal administration of HY peptides
    • Chai J.G., James E., Dewchand H., Simpson E., Scott D. Transplantation tolerance induced by intranasal administration of HY peptides. Blood 2004, 103:3951-3959.
    • (2004) Blood , vol.103 , pp. 3951-3959
    • Chai, J.G.1    James, E.2    Dewchand, H.3    Simpson, E.4    Scott, D.5
  • 42
    • 42149141724 scopus 로고    scopus 로고
    • Induction of antigen-specific regulatory T cells in wild-type mice: visualization and targets of suppression
    • Verginis P., McLaughlin K.A., Wucherpfennig K.W., von Boehmer H., Apostolou I. Induction of antigen-specific regulatory T cells in wild-type mice: visualization and targets of suppression. Proc Natl Acad Sci USA 2008, 105:3479-3484.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 3479-3484
    • Verginis, P.1    McLaughlin, K.A.2    Wucherpfennig, K.W.3    von Boehmer, H.4    Apostolou, I.5
  • 43
    • 79955680455 scopus 로고    scopus 로고
    • Antigen-specific induction of regulatory T cells in vivo and in vitro
    • Daniel C., Ploegh H., von Boehmer H. Antigen-specific induction of regulatory T cells in vivo and in vitro. Methods Mol Biol 2011, 707:173-185.
    • (2011) Methods Mol Biol , vol.707 , pp. 173-185
    • Daniel, C.1    Ploegh, H.2    von Boehmer, H.3
  • 44
    • 0002384347 scopus 로고
    • Induction of immunological paralysis in two zones of dosage
    • Mitchison N.A. Induction of immunological paralysis in two zones of dosage. Proc Roy Soc 1964, 161:275-292.
    • (1964) Proc Roy Soc , vol.161 , pp. 275-292
    • Mitchison, N.A.1
  • 45
    • 0000017701 scopus 로고
    • Specific inhibition of antibody production. I. Protein-overloading paralysis
    • Dresser D.W. Specific inhibition of antibody production. I. Protein-overloading paralysis. Immunology 1962, 5:161-168.
    • (1962) Immunology , vol.5 , pp. 161-168
    • Dresser, D.W.1
  • 46
    • 0000017699 scopus 로고
    • Specific inhibition of antibody production. II. Paralysis induced in mice by small quantities of protein antigen
    • Dresser D.W. Specific inhibition of antibody production. II. Paralysis induced in mice by small quantities of protein antigen. Immunology 1962, 5:378-388.
    • (1962) Immunology , vol.5 , pp. 378-388
    • Dresser, D.W.1
  • 47
    • 0014595585 scopus 로고
    • Immunological tolerance induced in adult dogs by small amounts of horse IgG
    • Land W., Seifert J., Fateh-Moghadam A., Hopf U., Brendel W. Immunological tolerance induced in adult dogs by small amounts of horse IgG. Transplantation 1969, 8:748-750.
    • (1969) Transplantation , vol.8 , pp. 748-750
    • Land, W.1    Seifert, J.2    Fateh-Moghadam, A.3    Hopf, U.4    Brendel, W.5
  • 48
    • 0014688060 scopus 로고
    • Induction of tolerance in man to horse-IgG
    • Brendel W., Land W., Hopf U., Seifert J. Induction of tolerance in man to horse-IgG. Lancet 1969, 2:1141-1142.
    • (1969) Lancet , vol.2 , pp. 1141-1142
    • Brendel, W.1    Land, W.2    Hopf, U.3    Seifert, J.4
  • 49
    • 33745712701 scopus 로고    scopus 로고
    • Immunosuppressive strategies in organ transplantation in the light of innate immunity
    • Land W.G. Immunosuppressive strategies in organ transplantation in the light of innate immunity. Exp Clin Transplant 2006, 4:406-415.
    • (2006) Exp Clin Transplant , vol.4 , pp. 406-415
    • Land, W.G.1
  • 50
    • 34147103219 scopus 로고    scopus 로고
    • Innate immunity-mediated allograft rejection and strategies to prevent it
    • Land W.G. Innate immunity-mediated allograft rejection and strategies to prevent it. Transplant Proc 2007, 39:667-672.
    • (2007) Transplant Proc , vol.39 , pp. 667-672
    • Land, W.G.1
  • 51
    • 70349218771 scopus 로고    scopus 로고
    • Normothermic ex vivo perfusion prevents lung injury compared to extended cold preservation for transplantation
    • Cypel M., Rubacha M., Yeung J., Hirayama S., Torbicki K., Madonik M., et al. Normothermic ex vivo perfusion prevents lung injury compared to extended cold preservation for transplantation. Am J Transplant 2009, 9:2262-2269.
    • (2009) Am J Transplant , vol.9 , pp. 2262-2269
    • Cypel, M.1    Rubacha, M.2    Yeung, J.3    Hirayama, S.4    Torbicki, K.5    Madonik, M.6
  • 52
    • 47149098182 scopus 로고    scopus 로고
    • NOX enzymes as novel targets for drug development
    • Lambeth J.D., Krause K.H., Clark R.A. NOX enzymes as novel targets for drug development. Semin Immunopathol 2008, 30:339-363.
    • (2008) Semin Immunopathol , vol.30 , pp. 339-363
    • Lambeth, J.D.1    Krause, K.H.2    Clark, R.A.3
  • 53
    • 67651156448 scopus 로고    scopus 로고
    • Small molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets
    • Jaquet V., Scapozza L., Clark R., Krause K.H., Lambeth J.D. Small molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets. Antioxid Redox Signal 2009, 11:2535-2552.
    • (2009) Antioxid Redox Signal , vol.11 , pp. 2535-2552
    • Jaquet, V.1    Scapozza, L.2    Clark, R.3    Krause, K.H.4    Lambeth, J.D.5
  • 56
    • 62349137054 scopus 로고    scopus 로고
    • Update on emerging urate-lowering therapies
    • Chohan S., Becker M.A. Update on emerging urate-lowering therapies. Curr Opin Rheumatol 2009, 21:143-149.
    • (2009) Curr Opin Rheumatol , vol.21 , pp. 143-149
    • Chohan, S.1    Becker, M.A.2
  • 57
    • 61549089406 scopus 로고    scopus 로고
    • Febuxostat in the management of hyperuricemia and chronic gout: a review
    • Hu M., Tomlinson B. Febuxostat in the management of hyperuricemia and chronic gout: a review. Ther Clin Risk Manag 2008, 4:1209-1220.
    • (2008) Ther Clin Risk Manag , vol.4 , pp. 1209-1220
    • Hu, M.1    Tomlinson, B.2
  • 58
    • 0141815741 scopus 로고    scopus 로고
    • Production of reactive oxygen species by mitochondria: central role of complex III
    • Chen Q., Vazquez E.J., Moghaddas S., Hoppel C.L., Lesnefsky E.J. Production of reactive oxygen species by mitochondria: central role of complex III. J Biol Chem 2003, 278:36027-36031.
    • (2003) J Biol Chem , vol.278 , pp. 36027-36031
    • Chen, Q.1    Vazquez, E.J.2    Moghaddas, S.3    Hoppel, C.L.4    Lesnefsky, E.J.5
  • 59
    • 78651238186 scopus 로고    scopus 로고
    • Mitochondrial superoxide anion radicals mediate induction of apoptosis in cardiac myoblasts exposed to chronic hypoxia
    • Kolamunne R.T., Clare M., Griffiths H.R. Mitochondrial superoxide anion radicals mediate induction of apoptosis in cardiac myoblasts exposed to chronic hypoxia. Arch Biochem Biophys 2011, 505:256-265.
    • (2011) Arch Biochem Biophys , vol.505 , pp. 256-265
    • Kolamunne, R.T.1    Clare, M.2    Griffiths, H.R.3
  • 60
    • 77951241278 scopus 로고    scopus 로고
    • Terpestacin inhibits tumor angiogenesis by targeting UQCRB of mitochondrial complex III and suppressing hypoxia-induced reactive oxygen species production and cellular oxygen sensing
    • Jung H.J., Shim J.S., Lee J., Song Y.M., Park K.C., Choi S.H., et al. Terpestacin inhibits tumor angiogenesis by targeting UQCRB of mitochondrial complex III and suppressing hypoxia-induced reactive oxygen species production and cellular oxygen sensing. J Biol Chem 2010, 285:11584-11595.
    • (2010) J Biol Chem , vol.285 , pp. 11584-11595
    • Jung, H.J.1    Shim, J.S.2    Lee, J.3    Song, Y.M.4    Park, K.C.5    Choi, S.H.6
  • 61
    • 0036022636 scopus 로고    scopus 로고
    • Protective effects of M40403, a selective superoxide dismutase mimetic, in myocardial ischaemia and reperfusion injury in vivo
    • Masini E., Cuzzocrea S., Mazzon E., Marzocca C., Mannaioni P.F., Salvemini D. Protective effects of M40403, a selective superoxide dismutase mimetic, in myocardial ischaemia and reperfusion injury in vivo. Br J Pharmacol 2002, 136:905-917.
    • (2002) Br J Pharmacol , vol.136 , pp. 905-917
    • Masini, E.1    Cuzzocrea, S.2    Mazzon, E.3    Marzocca, C.4    Mannaioni, P.F.5    Salvemini, D.6
  • 62
    • 0028292964 scopus 로고
    • Protective effects of MCI-186 on cerebral ischemia: possible involvement of free radical scavenging and antioxidant actions
    • Watanabe T., Yuki S., Egawa M., Nishi H. Protective effects of MCI-186 on cerebral ischemia: possible involvement of free radical scavenging and antioxidant actions. J Pharmacol Exp Ther 1994, 268:1597-1604.
    • (1994) J Pharmacol Exp Ther , vol.268 , pp. 1597-1604
    • Watanabe, T.1    Yuki, S.2    Egawa, M.3    Nishi, H.4
  • 63
    • 0027967666 scopus 로고
    • Effects of an antistroke agent MCI-186 on cerebral arachidonate cascade
    • Watanabe T., Egawa M. Effects of an antistroke agent MCI-186 on cerebral arachidonate cascade. J Pharmacol Exp Ther 1994, 271:1624-1629.
    • (1994) J Pharmacol Exp Ther , vol.271 , pp. 1624-1629
    • Watanabe, T.1    Egawa, M.2
  • 64
    • 23044516263 scopus 로고    scopus 로고
    • A radical scavenger, edaravone, protects canine kidneys from ischemia-reperfusion injury after 72 hours of cold preservation and autotransplantation
    • Tahara M., Nakayama M., Jin M.B., Fujita M., Suzuki T., Taniguchi M., et al. A radical scavenger, edaravone, protects canine kidneys from ischemia-reperfusion injury after 72 hours of cold preservation and autotransplantation. Transplantation 2005, 80:213-221.
    • (2005) Transplantation , vol.80 , pp. 213-221
    • Tahara, M.1    Nakayama, M.2    Jin, M.B.3    Fujita, M.4    Suzuki, T.5    Taniguchi, M.6
  • 65
    • 14944364012 scopus 로고    scopus 로고
    • MCI-186 (free radical scavenger) induce prolonged survival of fully-allogeneic cardiac grafts
    • Tanaka K., Shirasugi N., Inoue F., et al. MCI-186 (free radical scavenger) induce prolonged survival of fully-allogeneic cardiac grafts. Am J Transplant 2004, 4:527.
    • (2004) Am J Transplant , vol.4 , pp. 527
    • Tanaka, K.1    Shirasugi, N.2    Inoue, F.3
  • 66
    • 79551482502 scopus 로고    scopus 로고
    • Donor antioxidant strategy prolongs cardiac allograft survival by attenuating tissue dendritic cell immunogenicity
    • Jurewicz M., Ueno T., Azzi J., Tanaka K., Murayama T., Yang S., et al. Donor antioxidant strategy prolongs cardiac allograft survival by attenuating tissue dendritic cell immunogenicity. Am J Transplant 2011, 11:348-355.
    • (2011) Am J Transplant , vol.11 , pp. 348-355
    • Jurewicz, M.1    Ueno, T.2    Azzi, J.3    Tanaka, K.4    Murayama, T.5    Yang, S.6
  • 69
    • 40949119062 scopus 로고    scopus 로고
    • Emerging science, emerging ethical issues: who should fund innate alloimmunity-suppressing drugs?
    • Land W.G., Gutmann T., Daar A.S. Emerging science, emerging ethical issues: who should fund innate alloimmunity-suppressing drugs?. Acta Chir Belg 2008, 108:73-82.
    • (2008) Acta Chir Belg , vol.108 , pp. 73-82
    • Land, W.G.1    Gutmann, T.2    Daar, A.S.3
  • 71
    • 40649099165 scopus 로고    scopus 로고
    • Inhibition of terminal complement components in presensitized transplant recipients prevents antibody-mediated rejection leading to long-term graft survival and accommodation
    • Wang H., Arp J., Liu W., Faas S.J., Jiang J., Gies D.R., et al. Inhibition of terminal complement components in presensitized transplant recipients prevents antibody-mediated rejection leading to long-term graft survival and accommodation. J Immunol 2007, 179:4451-4463.
    • (2007) J Immunol , vol.179 , pp. 4451-4463
    • Wang, H.1    Arp, J.2    Liu, W.3    Faas, S.J.4    Jiang, J.5    Gies, D.R.6
  • 73
    • 0015596479 scopus 로고
    • Reduction of immunogenicity of human cadaver renal allografts by donor pretreatment
    • Guttmann R.D., Beaudoin J.G., Morehouse D.D. Reduction of immunogenicity of human cadaver renal allografts by donor pretreatment. Transplant Proc 1973, 5:663-665.
    • (1973) Transplant Proc , vol.5 , pp. 663-665
    • Guttmann, R.D.1    Beaudoin, J.G.2    Morehouse, D.D.3
  • 74
    • 0017743056 scopus 로고
    • High dose (bolus) intravenous methylprednisolone at the time of kidney homotransplantation
    • Kauffman H.M., Sampson D., Fox P.S., Stawicki A.T. High dose (bolus) intravenous methylprednisolone at the time of kidney homotransplantation. Ann Surg 1977, 186:631-634.
    • (1977) Ann Surg , vol.186 , pp. 631-634
    • Kauffman, H.M.1    Sampson, D.2    Fox, P.S.3    Stawicki, A.T.4
  • 75
    • 58149388727 scopus 로고    scopus 로고
    • Methylprednisolone therapy in deceased donors reduces inflammation in the donor liver and improves outcome after liver transplantation: a prospective randomized controlled trial
    • Kotsch K., Ulrich F., Reutzel-Selke A., Pascher A., Faber W., Warnick P., et al. Methylprednisolone therapy in deceased donors reduces inflammation in the donor liver and improves outcome after liver transplantation: a prospective randomized controlled trial. Ann Surg 2008, 248:1042-1050.
    • (2008) Ann Surg , vol.248 , pp. 1042-1050
    • Kotsch, K.1    Ulrich, F.2    Reutzel-Selke, A.3    Pascher, A.4    Faber, W.5    Warnick, P.6
  • 76
    • 46749097131 scopus 로고    scopus 로고
    • Ischemic-reperfusion syndromes: biochemical and immunologic rationale for IL-1 targeted therapy
    • Wanderer A.A. Ischemic-reperfusion syndromes: biochemical and immunologic rationale for IL-1 targeted therapy. Clin Immunol 2008, 128:127-132.
    • (2008) Clin Immunol , vol.128 , pp. 127-132
    • Wanderer, A.A.1
  • 77
    • 42949169489 scopus 로고    scopus 로고
    • Administration of interleukin-1 receptor antagonist ameliorates renal ischemia-reperfusion injury
    • Rusai K., Huang H., Sayed N., Strobl M., Roos M., Schmaderer C., et al. Administration of interleukin-1 receptor antagonist ameliorates renal ischemia-reperfusion injury. Transpl Int 2008, 21:572-580.
    • (2008) Transpl Int , vol.21 , pp. 572-580
    • Rusai, K.1    Huang, H.2    Sayed, N.3    Strobl, M.4    Roos, M.5    Schmaderer, C.6
  • 78
    • 44349099704 scopus 로고    scopus 로고
    • Safety and efficacy of biologics directed against TNF-alpha and CD20 in the therapy of vasculitis and systemic lupus erythematosus
    • Walker U.A., Hasler P. Safety and efficacy of biologics directed against TNF-alpha and CD20 in the therapy of vasculitis and systemic lupus erythematosus. Ther Umsch 2008, 65:303-310.
    • (2008) Ther Umsch , vol.65 , pp. 303-310
    • Walker, U.A.1    Hasler, P.2
  • 79
    • 48849115457 scopus 로고    scopus 로고
    • Biological therapy for the treatment of rheumatic diseases
    • Pierer M., Baerwald C. Biological therapy for the treatment of rheumatic diseases. Internist (Berl) 2008, 49:938-946.
    • (2008) Internist (Berl) , vol.49 , pp. 938-946
    • Pierer, M.1    Baerwald, C.2
  • 81
    • 49749100079 scopus 로고    scopus 로고
    • NOX4 regulates ROS levels under normoxic and hypoxic conditions, triggers proliferation, and inhibits apoptosis in pulmonary artery adventitial fibroblasts
    • Li S., Tabar S.S., Malec V., Eul B.G., Klepetko W., Weissmann N., et al. NOX4 regulates ROS levels under normoxic and hypoxic conditions, triggers proliferation, and inhibits apoptosis in pulmonary artery adventitial fibroblasts. Antioxid Redox Signal 2008, 10:1687-1698.
    • (2008) Antioxid Redox Signal , vol.10 , pp. 1687-1698
    • Li, S.1    Tabar, S.S.2    Malec, V.3    Eul, B.G.4    Klepetko, W.5    Weissmann, N.6
  • 83
    • 77955716367 scopus 로고    scopus 로고
    • Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury
    • Ben Mkaddem S., Pedruzzi E., Werts C., Coant N., Bens M., Cluzeaud F., et al. Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury. Cell Death Differ 2010, 17:1474-1485.
    • (2010) Cell Death Differ , vol.17 , pp. 1474-1485
    • Ben Mkaddem, S.1    Pedruzzi, E.2    Werts, C.3    Coant, N.4    Bens, M.5    Cluzeaud, F.6
  • 84
    • 33845951057 scopus 로고    scopus 로고
    • Prevention of renal ischemic injury by silencing the expression of renal caspase 3 and caspase 8
    • Zhang X., Zheng X., Sun H., Feng B., Chen G., Vladau C., et al. Prevention of renal ischemic injury by silencing the expression of renal caspase 3 and caspase 8. Transplantation 2006, 82:1728-1732.
    • (2006) Transplantation , vol.82 , pp. 1728-1732
    • Zhang, X.1    Zheng, X.2    Sun, H.3    Feng, B.4    Chen, G.5    Vladau, C.6
  • 85
    • 33746897348 scopus 로고    scopus 로고
    • Preventing renal ischemia-reperfusion injury using small interfering RNA by targeting complement 3 gene
    • Zheng X., Feng B., Chen G., Zhang X., Li M., Sun H., et al. Preventing renal ischemia-reperfusion injury using small interfering RNA by targeting complement 3 gene. Am J Transplant 2006, 6:2099-2108.
    • (2006) Am J Transplant , vol.6 , pp. 2099-2108
    • Zheng, X.1    Feng, B.2    Chen, G.3    Zhang, X.4    Li, M.5    Sun, H.6
  • 86
    • 33845914939 scopus 로고    scopus 로고
    • Protection of renal ischemia injury using combination gene silencing of complement 3 and caspase 3 genes
    • Zheng X., Zhang X., Sun H., Feng B., Li M., Chen G., et al. Protection of renal ischemia injury using combination gene silencing of complement 3 and caspase 3 genes. Transplantation 2006, 82:1781-1786.
    • (2006) Transplantation , vol.82 , pp. 1781-1786
    • Zheng, X.1    Zhang, X.2    Sun, H.3    Feng, B.4    Li, M.5    Chen, G.6
  • 87
    • 79952589144 scopus 로고    scopus 로고
    • Promises and challenges in developing RNAi as a research tool and therapy
    • Sioud M. Promises and challenges in developing RNAi as a research tool and therapy. Methods Mol Biol 2011, 703:173-187.
    • (2011) Methods Mol Biol , vol.703 , pp. 173-187
    • Sioud, M.1
  • 88
    • 77952296761 scopus 로고    scopus 로고
    • Preventing immune rejection through gene silencing
    • Zhang X., Li M., Min W.P. Preventing immune rejection through gene silencing. Methods Mol Biol 2010, 623:357-371.
    • (2010) Methods Mol Biol , vol.623 , pp. 357-371
    • Zhang, X.1    Li, M.2    Min, W.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.