Isosteviol has beneficial effects on palmitate-induced α-cell dysfunction and gene expression

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Chen, Xiaoping ^a,b   Hermansen, Kjeld ^a   Xiao, Jianzhong ^b   Bystrup, Sara Kjaergaard ^a   O'Driscoll, Lorraine ^c   Jeppesen, Per Bendix ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b CHINA JAPAN FRIENDSHIP HOSPITAL   (China)

^c TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ACETYL COENZYME A CARBOXYLASE ALPHA; ANTIDIABETIC AGENT; FATTY ACID; FATTY ACID SYNTHASE; GLUCAGON; INSULIN; INSULIN RECEPTOR SUBSTRATE 2; ISOSTEVIOL; MESSENGER RNA; PALMITIC ACID; PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 2; SERINE PROTEINASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRANSCRIPTION FACTOR PAX6; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; GLUCOSE; KAURANE DERIVATIVE; PALMITIC ACID DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL CLONE; CELL INTERACTION; CELL LEVEL; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; FATTY ACID METABOLISM; FEMALE; GENE EXPRESSION REGULATION; GLUCAGON RELEASE; HORMONE SYNTHESIS; INCUBATION TIME; INSULIN METABOLISM; LONG TERM EXPOSURE; MITOSIS RATE; MOUSE; NONHUMAN; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PANCREAS ISLET DISEASE; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; CELL CULTURE; DRUG EFFECT; GENETICS; METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS;

ANIMALS; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; DITERPENES, KAURANE; FATTY ACIDS; FEMALE; GENE EXPRESSION REGULATION; GLUCAGON; GLUCAGON-SECRETING CELLS; GLUCOSE; HYPOGLYCEMIC AGENTS; INSULIN; MICE; PALMITATES;

EID: 84858958992     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0034361     Document Type: Article

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