Isosteviol increases insulin sensitivity and changes gene expression of key insulin regulatory genes and transcription factors in islets of the diabetic KKAy mouse

Diabetes, Obesity and Metabolism

Volumn 10, Issue 10, 2008, Pages 939-949

  Nordentoft, Iver ^a   Jeppesen, P B ^a   Hong, J ^a   Abudula, R ^a   Hermansen, K ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Beta cell transcription factors; Insulin sensitizer; Islets; Isosteviol; KKAy mouse; Microarray; Real time RT PCR; T2DM

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; 11BETA HYDROXYSTEROID DEHYDROGENASE 1; ANTIDIABETIC AGENT; CCAAT ENHANCER BINDING PROTEIN ALPHA; DITERPENE; GLUCOSE; GLUCOSE TRANSPORTER 2; HEPATOCYTE NUCLEAR FACTOR 3BETA; INSULIN; INSULIN 1; INSULIN 2; INSULIN DERIVATIVE; ISOSTEVIOL; NEUROGENIC DIFFERENTIATION FACTOR; RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NKX2.2; TRANSCRIPTION FACTOR NKX6.1; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR PDX 1; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DIABETES MELLITUS; DIET; DRUG EFFECT; FEMALE; GENE EXPRESSION; GLUCOSE HOMEOSTASIS; IN VIVO STUDY; INSULIN SENSITIVITY; MALE; METABOLISM; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS ISLET; REAL TIME POLYMERASE CHAIN REACTION; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 52249101557     PISSN: 14628902     EISSN: 14631326     Source Type: Journal    
DOI: 10.1111/j.1463-1326.2007.00836.x     Document Type: Article

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