메뉴 건너뛰기




Volumn 290, Issue 3, 2006, Pages

Stevioside counteracts the α-cell hypersecretion caused by long-term palmitate exposure

Author keywords

TC1 6 cells; Fatty acids; Gene expression; Glucagon

Indexed keywords

ACYL COENZYME A DESATURASE; ANTIDIABETIC AGENT; CARNITINE PALMITOYLTRANSFERASE; GLUCAGON; MESSENGER RNA; PALMITIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; STEVIOSIDE; TRIACYLGLYCEROL; ACETYL COENZYME A CARBOXYLASE; GLUCOSIDE; KAURANE DERIVATIVE; PALMITIC ACID DERIVATIVE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 33645079427     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00331.2005     Document Type: Article
Times cited : (31)

References (34)
  • 1
    • 0031019883 scopus 로고    scopus 로고
    • Fatty acids rapidly induce the carnitine palmitoyltransferase I gene in the pancreatic beta-cell line INS-1
    • Assimacopoulos-Jeannet F, Thumelin S, Roche E, Esser V, McGarry JD, and Prentki M. Fatty acids rapidly induce the carnitine palmitoyltransferase I gene in the pancreatic beta-cell line INS-1. J Biol Chem 272: 1659-1664, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 1659-1664
    • Assimacopoulos-Jeannet, F.1    Thumelin, S.2    Roche, E.3    Esser, V.4    McGarry, J.D.5    Prentki, M.6
  • 2
    • 0036230225 scopus 로고    scopus 로고
    • Expression profiling of palmitate- and oleate-regulated genes provides novel insights into the effects of chronic lipid exposure on pancreatic beta-cell function
    • Busch AK, Cordery D, Denyer GS, and Biden TJ. Expression profiling of palmitate- and oleate-regulated genes provides novel insights into the effects of chronic lipid exposure on pancreatic beta-cell function. Diabetes 51: 977-987, 2002.
    • (2002) Diabetes , vol.51 , pp. 977-987
    • Busch, A.K.1    Cordery, D.2    Denyer, G.S.3    Biden, T.J.4
  • 3
    • 14944361919 scopus 로고    scopus 로고
    • Mechanism of the hypoglycemic effect of stevioside, a glycoside of Stevia rebaudiana
    • Chen TH, Chen SC, Chan P, Chu YL, Yang HY, and Cheng JT. Mechanism of the hypoglycemic effect of stevioside, a glycoside of Stevia rebaudiana. Planta Med 71: 108-113, 2005.
    • (2005) Planta Med , vol.71 , pp. 108-113
    • Chen, T.H.1    Chen, S.C.2    Chan, P.3    Chu, Y.L.4    Yang, H.Y.5    Cheng, J.T.6
  • 5
    • 0037122801 scopus 로고    scopus 로고
    • Fat in all the wrong places
    • Friedman J. Fat in all the wrong places. Nature 415: 268-269, 2002.
    • (2002) Nature , vol.415 , pp. 268-269
    • Friedman, J.1
  • 6
    • 0025269469 scopus 로고
    • Comparison of cytokine effects on mouse pancreatic alpha-cell and beta-cell lines. Viability, secretory function, and MHC antigen expression
    • Hamaguchi K and Leiter EH. Comparison of cytokine effects on mouse pancreatic alpha-cell and beta-cell lines. Viability, secretory function, and MHC antigen expression. Diabetes 39: 415-425, 1990.
    • (1990) Diabetes , vol.39 , pp. 415-425
    • Hamaguchi, K.1    Leiter, E.H.2
  • 7
    • 24344458875 scopus 로고    scopus 로고
    • The acute effect of fatty acids on glucagon secretion is influenced by their chain length, spatial configuration and degree of unsaturation: Studies in vitro
    • Hong J, Abudula R, Chen J, Jeppesen PB, Dyrskog SEU, Colombo M, and Hermansen K. The acute effect of fatty acids on glucagon secretion is influenced by their chain length, spatial configuration and degree of unsaturation: Studies in vitro. Metabolism. 54: 1329-1336, 2005.
    • (2005) Metabolism , vol.54 , pp. 1329-1336
    • Hong, J.1    Abudula, R.2    Chen, J.3    Jeppesen, P.B.4    Dyrskog, S.E.U.5    Colombo, M.6    Hermansen, K.7
  • 8
    • 0036190439 scopus 로고    scopus 로고
    • Stevioside induces antihyperglycaemic, insulinotropic and glucagonostatic effects in vivo: Studies in the diabetic Goto-Kakizaki (GK) rats
    • Jeppesen PB, Gregersen S, Alstrup KK, and Hermansen K. Stevioside induces antihyperglycaemic, insulinotropic and glucagonostatic effects in vivo: studies in the diabetic Goto-Kakizaki (GK) rats. Phytomedicine 9: 9-14, 2002.
    • (2002) Phytomedicine , vol.9 , pp. 9-14
    • Jeppesen, P.B.1    Gregersen, S.2    Alstrup, K.K.3    Hermansen, K.4
  • 9
    • 0033952852 scopus 로고    scopus 로고
    • Stevioside acts directly on pancreatic beta cells to secrete insulin: Actions independent of cyclic adenosine monophosphate and adenosine triphosphate-sensitive K+-channel activity
    • Jeppesen PB, Gregersen S, Poulsen CR, and Hermansen K. Stevioside acts directly on pancreatic beta cells to secrete insulin: actions independent of cyclic adenosine monophosphate and adenosine triphosphate-sensitive K+-channel activity. Metabolism 49: 208-214, 2000.
    • (2000) Metabolism , vol.49 , pp. 208-214
    • Jeppesen, P.B.1    Gregersen, S.2    Poulsen, C.R.3    Hermansen, K.4
  • 11
    • 0042531617 scopus 로고    scopus 로고
    • Palmitate inhibition of insulin gene expression is mediated at the transcriptional level via ceramide synthesis
    • Kelpe CL, Moore PC, Parazzoli SD, Wicksteed B, Rhodes CJ, and Poitout V. Palmitate inhibition of insulin gene expression is mediated at the transcriptional level via ceramide synthesis. J Biol Chem 278: 30015-30021, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 30015-30021
    • Kelpe, C.L.1    Moore, P.C.2    Parazzoli, S.D.3    Wicksteed, B.4    Rhodes, C.J.5    Poitout, V.6
  • 12
    • 0028919521 scopus 로고
    • Expression of insulin receptor on clonal pancreatic alpha cells and its possible role for insulin-stimulated negative regulation of glucagon secretion
    • Kisanuki K, Kishikawa H, Araki E, Shirotani T, Uehara M, Isami S, Ura S, Jinnouchi H, Miyamura N, and Shichiri M. Expression of insulin receptor on clonal pancreatic alpha cells and its possible role for insulin-stimulated negative regulation of glucagon secretion. Diabetologia 38: 422-429, 1995.
    • (1995) Diabetologia , vol.38 , pp. 422-429
    • Kisanuki, K.1    Kishikawa, H.2    Araki, E.3    Shirotani, T.4    Uehara, M.5    Isami, S.6    Ura, S.7    Jinnouchi, H.8    Miyamura, N.9    Shichiri, M.10
  • 13
    • 0035156817 scopus 로고    scopus 로고
    • Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and function
    • Maedler K, Spinas GA, Dyntar D, Moritz W, Kaiser N, and Donath MY. Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and function. Diabetes 50: 69-76, 2001.
    • (2001) Diabetes , vol.50 , pp. 69-76
    • Maedler, K.1    Spinas, G.A.2    Dyntar, D.3    Moritz, W.4    Kaiser, N.5    Donath, M.Y.6
  • 14
    • 0026058327 scopus 로고
    • New insights into the mitochondrial carnitine palmitoyltransferase enzyme system
    • McGarry JD, Sen A, Esser V, Woeltje KF, Weis B, and Foster DW. New insights into the mitochondrial carnitine palmitoyltransferase enzyme system. Biochimie 73: 77-84, 1991.
    • (1991) Biochimie , vol.73 , pp. 77-84
    • McGarry, J.D.1    Sen, A.2    Esser, V.3    Woeltje, K.F.4    Weis, B.5    Foster, D.W.6
  • 16
    • 14144256749 scopus 로고    scopus 로고
    • Differentiation phenotypes of pancreatic islet beta- and alpha-cells are closely related with homeotic genes and a group of differentially expressed genes
    • Mizusawa N, Hasegawa T, Ohigashi I, Tanaka-Kosugi C, Harada N, Itakura M, and Yoshimoto K. Differentiation phenotypes of pancreatic islet beta- and alpha-cells are closely related with homeotic genes and a group of differentially expressed genes. Gene 331: 53-63, 2004.
    • (2004) Gene , vol.331 , pp. 53-63
    • Mizusawa, N.1    Hasegawa, T.2    Ohigashi, I.3    Tanaka-Kosugi, C.4    Harada, N.5    Itakura, M.6    Yoshimoto, K.7
  • 17
    • 0036294713 scopus 로고    scopus 로고
    • SREBP-1: Gene regulatory key to syndrome X?
    • Muller-Wieland D and Kotzka J. SREBP-1: gene regulatory key to syndrome X? Ann NY Acad Sci 967: 19-27, 2002.
    • (2002) Ann NY Acad Sci , vol.967 , pp. 19-27
    • Muller-Wieland, D.1    Kotzka, J.2
  • 18
    • 0032871502 scopus 로고    scopus 로고
    • Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol
    • Ntambi JM. Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol. J Lipid Res 40: 1549-1558, 1999.
    • (1999) J Lipid Res , vol.40 , pp. 1549-1558
    • Ntambi, J.M.1
  • 20
    • 3042551249 scopus 로고    scopus 로고
    • Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation
    • Perdomo G, Commerford SR, Richard AM, Adams SH, Corkey BE, O'Doherty RM, and Brown NF. Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation. J Biol Chem 279: 27177-27186, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 27177-27186
    • Perdomo, G.1    Commerford, S.R.2    Richard, A.M.3    Adams, S.H.4    Corkey, B.E.5    O'Doherty, R.M.6    Brown, N.F.7
  • 21
    • 0036896505 scopus 로고    scopus 로고
    • Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: Role in beta-cell adaptation and failure in the etiology of diabetes
    • Prentki M, Joly E, El Assaad W, and Roduit R. Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in beta-cell adaptation and failure in the etiology of diabetes. Diabetes 51, Suppl 3: S405-S413, 2002.
    • (2002) Diabetes , vol.51 , Issue.3 SUPPL.
    • Prentki, M.1    Joly, E.2    El Assaad, W.3    Roduit, R.4
  • 22
    • 12744279669 scopus 로고    scopus 로고
    • Diabetes: Insulin resistance and derangements in lipid metabolism. Cure through intervention in fat transport and storage
    • Raz I, Eldor R, Cernea S, and Shafrir E. Diabetes: insulin resistance and derangements in lipid metabolism. Cure through intervention in fat transport and storage. Diabetes Metab Res Rev 21: 3-14, 2005.
    • (2005) Diabetes Metab Res Rev , vol.21 , pp. 3-14
    • Raz, I.1    Eldor, R.2    Cernea, S.3    Shafrir, E.4
  • 23
    • 0037093532 scopus 로고    scopus 로고
    • Adenovirus-mediated overexpression of liver carnitine palmitoyltransferase I in INS1E cells: Effects on cell metabolism and insulin secretion
    • Rubi B, Antinozzi PA, Herrero L, Ishihara H, Asins G, Serra D, Wollheim CB, Maechler P, and Hegardt FG. Adenovirus-mediated overexpression of liver carnitine palmitoyltransferase I in INS1E cells: effects on cell metabolism and insulin secretion. Biochem J 364: 219-226, 2002.
    • (2002) Biochem J , vol.364 , pp. 219-226
    • Rubi, B.1    Antinozzi, P.A.2    Herrero, L.3    Ishihara, H.4    Asins, G.5    Serra, D.6    Wollheim, C.B.7    Maechler, P.8    Hegardt, F.G.9
  • 24
    • 0038509036 scopus 로고    scopus 로고
    • Lipotoxicity: When tissues overeat
    • Schaffer JE. Lipotoxicity: when tissues overeat. Curr Opin Lipidol 14: 281-287, 2003.
    • (2003) Curr Opin Lipidol , vol.14 , pp. 281-287
    • Schaffer, J.E.1
  • 27
    • 0036182137 scopus 로고    scopus 로고
    • Lipotoxic diseases
    • Unger RH. Lipotoxic diseases. Annu Rev Med 53: 319-336, 2002.
    • (2002) Annu Rev Med , vol.53 , pp. 319-336
    • Unger, R.H.1
  • 28
    • 0016423677 scopus 로고
    • The essential role of glucagon in the pathogenesis of diabetes mellitus
    • Unger RH and Orci L. The essential role of glucagon in the pathogenesis of diabetes mellitus. Lancet 1: 14-16, 1975.
    • (1975) Lancet , vol.1 , pp. 14-16
    • Unger, R.H.1    Orci, L.2
  • 29
    • 0242300119 scopus 로고    scopus 로고
    • Contrasting patterns of expression of transcription factors in pancreatic alpha and beta cells
    • Wang J, Webb G, Cao Y, and Steiner DF. Contrasting patterns of expression of transcription factors in pancreatic alpha and beta cells. Proc Natl Acad Sci USA 100: 12660-12665, 2003.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 12660-12665
    • Wang, J.1    Webb, G.2    Cao, Y.3    Steiner, D.F.4
  • 30
    • 1342286820 scopus 로고    scopus 로고
    • Mono-unsaturated fatty acids protect against beta-cell apoptosis induced by saturated fatty acids, serum withdrawal or cytokine exposure
    • Welters HJ, Tadayyon M, Scarpello JH, Smith SA, and Morgan NG. Mono-unsaturated fatty acids protect against beta-cell apoptosis induced by saturated fatty acids, serum withdrawal or cytokine exposure. FEBS Lett 560: 103-108, 2004.
    • (2004) FEBS Lett , vol.560 , pp. 103-108
    • Welters, H.J.1    Tadayyon, M.2    Scarpello, J.H.3    Smith, S.A.4    Morgan, N.G.5
  • 31
    • 0034751632 scopus 로고    scopus 로고
    • The effect of chronic exposure to fatty acids on gene expression in clonal insulin-producing cells: Studies using high density oligonucleotide microarray
    • Xiao J, Gregersen S, Kruhoffer M, Pedersen SB, Orntoft TF, and Hermansen K. The effect of chronic exposure to fatty acids on gene expression in clonal insulin-producing cells: studies using high density oligonucleotide microarray. Endocrinology 142: 4777-4784, 2001.
    • (2001) Endocrinology , vol.142 , pp. 4777-4784
    • Xiao, J.1    Gregersen, S.2    Kruhoffer, M.3    Pedersen, S.B.4    Orntoft, T.F.5    Hermansen, K.6
  • 32
    • 0036178850 scopus 로고    scopus 로고
    • Differential impact of acute and chronic lipotoxicity on gene expression in INS-1 cells
    • Xiao J, Gregersen S, Pedersen SB, and Hermansen K. Differential impact of acute and chronic lipotoxicity on gene expression in INS-1 cells. Metabolism 51: 155-162, 2002.
    • (2002) Metabolism , vol.51 , pp. 155-162
    • Xiao, J.1    Gregersen, S.2    Pedersen, S.B.3    Hermansen, K.4
  • 33
    • 0028268936 scopus 로고
    • Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle
    • Zhou YP and Grill VE. Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle. J Clin Invest 93: 870-876, 1994.
    • (1994) J Clin Invest , vol.93 , pp. 870-876
    • Zhou, Y.P.1    Grill, V.E.2
  • 34
    • 0031738017 scopus 로고    scopus 로고
    • Enhanced de novo lipogenesis in the leptin-unresponsive pancreatic islets of prediabetic Zucker diabetic fatty rats: Role in the pathogenesis of lipotoxic diabetes
    • Zhou YT, Shimabukuro M, Lee Y, Koyama K, Higa M, Ferguson T, and Unger RH. Enhanced de novo lipogenesis in the leptin-unresponsive pancreatic islets of prediabetic Zucker diabetic fatty rats: role in the pathogenesis of lipotoxic diabetes. Diabetes 47: 1904-1908, 1998.
    • (1998) Diabetes , vol.47 , pp. 1904-1908
    • Zhou, Y.T.1    Shimabukuro, M.2    Lee, Y.3    Koyama, K.4    Higa, M.5    Ferguson, T.6    Unger, R.H.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.