The 5-HT 7 receptor in learning and memory

Hippocampus

Volumn 22, Issue 4, 2012, Pages 762-771

  Roberts, Amanda J ^a   Hedlund, Peter B ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Barnes maze; Fear conditioning; Object exploration; Place learning; Spatial learning

Indexed keywords

3 [2 [2 (4 METHYL 1 PIPERIDINYL)ETHYL] 1 PYRROLIDINESULFONYL]PHENOL; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MESSENGER RNA; SEROTONIN 7 RECEPTOR;

BINDING SITE; BRAIN ELECTROPHYSIOLOGY; BRAIN FUNCTION; CENTRAL NERVOUS SYSTEM; COGNITION; DEPRESSION; ENZYME SYNTHESIS; EX VIVO STUDY; FEAR; HIPPOCAMPAL CA1 REGION; HIPPOCAMPUS; HYPOTHALAMUS; IMMUNOREACTIVITY; INTRACELLULAR SIGNALING; LEARNING; LONG TERM MEMORY; MAZE TEST; MEMORY; MEMORY DISORDER; MENTAL FUNCTION; MENTAL TASK; NEUROPSYCHOLOGICAL TEST; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RECEPTOR BINDING; REFERENCE MEMORY; REVIEW; SHORT TERM MEMORY; SYNAPSE; TASK PERFORMANCE; WORKING MEMORY;

ANIMALS; CONDITIONING (PSYCHOLOGY); ELECTROPHYSIOLOGICAL PHENOMENA; FEAR; HIPPOCAMPUS; HUMANS; LEARNING; MAZE LEARNING; MEMORY; MICE; MICE, KNOCKOUT; MODELS, NEUROLOGICAL; RATS; RECEPTORS, SEROTONIN; RNA, MESSENGER; SEROTONIN ANTAGONISTS; SIGNAL TRANSDUCTION;

EID: 84858753620     PISSN: 10509631     EISSN: 10981063     Source Type: Journal    
DOI: 10.1002/hipo.20938     Document Type: Review

References (92)

1. 7 antagonist: Relevance for antidepressant actions in vivo. Psychopharmacology (Berl) 205: 119-128.
2. Anagnostaras SG, Gale GD, Fanselow MS. 2001. Hippocampus and contextual fear conditioning: Recent controversies and advances. Hippocampus 11: 8-17.
3. Baarendse PJJ, van Grootheest G, Jansen RF, Pieneman AW, Ogren SO, Verhage M, Stiedl O. 2008. Differential involvement of the dorsal hippocampus in passive avoidance in C57bl/6J and DBA/2J mice. Hippocampus 18: 11-19.
4. Bach ME, Hawkins RD, Osman M, Kandel ER, Mayford M. 1995. Impairment of spatial but not contextual memory in CaMKII mutant mice with a selective loss of hippocampal LTP in the range of the theta frequency. Cell 81: 905-915.
5. Bacon WL, Beck SG. 2000. 5-Hydroxytryptamine7 receptor activation decreases slow afterhyperpolarization amplitude in CA3 hippocampal pyramidal cells. J Pharmacol Exp Ther 294: 672-679.
6. 7 receptor gene expression in rats showing differences in novelty-seeking behavior. Neuroscience 147: 428-438.
7. 7 receptor: Role in novel object discrimination and relation to novelty-seeking behavior. Neuroscience 149: 192-202.
8. 7) positively linked to adenylate cyclase. J Biol Chem 268: 23422-23426.
9. Barnes CA. 1979. Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat. J Comp Physiol Psychol 93: 74-104.
10. Beattie D, Smith J. 2008. Serotonin pharmacology in the gastrointestinal tract: A review. Naunyn Schmiedebergs Arch Pharmacol 377: 181-203.
11. 7 receptors in the mouse suprachiasmatic nucleus. J Comp Neurol 432: 371-388.
12. Benice T, Raber J. 2008. Object recognition analysis in mice using nose-point digital video tracking. J Neurosci Meth 168: 422-430.
13. Berke JD, Breck JT, Eichenbaum H. 2009. Striatal versus hippocampal representations during win-stay maze performance. J Neurophysiol 101: 1575-1587.
14. Bickmeyer U, Heine M, Manzke T, Richter DW. 2002. Differential modulation of Ih by 5-HT receptors in mouse CA1 hippocampal neurons. Eur J Neurosci 16: 209-218.
15. Bonaventure P, Nepomuceno D, Kwok A, Chai W, Langlois X, Hen R, Stark K, Carruthers N, Lovenberg TW. 2002. Reconsideration of 5-hydroxytryptamine (5-HT)(7) receptor distribution using [(3)H]5-carboxamidotryptamine and [(3)H]8-hydroxy-2-(di-n-propylamino)tetraline: Analysis in brain of 5-HT(1A) knockout and 5- HT(1A/1B) double-knockout mice. J Pharmacol Exp Ther 302: 240-248.
16. Bonaventure P, Nepomuceno D, Hein L, Sutcliffe JG, Lovenberg T, Hedlund PB. 2004. Radioligand binding analysis of knockout mice reveals 5-hydroxytryptamine7 receptor distribution and uncovers 8-hydroxy-2-(di-n-propylamino)tetralin interaction with α2 adrenergic receptors. Neuroscience 124: 901-911.
17. 7 receptors. J Neurochem 108: 1126-1135.
18. 7 receptor activation inhibits mechanical hypersensitivity secondary to capsaicin sensitization in mice. Pain 141: 239-247.
19. Burgess N. 2008. Spatial cognition and the brain. Ann NY Acad Sci 1124: 77-97.
20. 7 receptors in the modulation of cognitive processes. Behav Brain Res 195: 171-179.
21. Ennaceur A, Neave N, Aggleton JP. 1997. Spontaneous object recognition and object location memory in rats: The effects of lesions in the cingulate cortices, the medial prefrontal cortex, the cingulum bundle and the fornix. Exp Brain Res 113: 509-519.
22. 7 receptor stimulation by 8-OH-DPAT counteracts the impairing effect of 5-HT1A receptor stimulation on contextual learning in mice. Eur J Pharmacol 596: 107-110.
23. 7 receptors in the rat hippocampus. Gene Expr 13: 53-57.
24. 7 antagonist SB-269970 in the modulation of working and reference memory in the rat. Behav Brain Res 195: 164-170.
25. Glass JD, Grossman GH, Farnbauch L, DiNardo L. 2003. Midbrain raphe modulation of nonphotic circadian clock resetting and 5-HT release in the mammalian suprachiasmatic nucleus. J Neurosci 23: 7451-7460.
26. Goodrich-Hunsaker NJ, Hunsaker MR, Kesner RP. 2008. The interactions and dissociations of the dorsal hippocampus subregions: How the dentate gyrus, CA3, and CA1 process spatial information Behav Neurosci 122: 16-26.
27. 7 receptor positively coupled to adenylate cyclase activation in human granulosa-lutein cells. J Clin Endocrin Met 85: 1277-1286.
28. 7 receptor suggest therapeutic potential in depression. Neuropharmacology 48: 492-502.
29. Gustafson EL, Durkin MM, Bard JA, Zgombick J, Branchek TA. 1996. A receptor autoradiographic and in situ hybridization analysis of the distribution of the 5-ht7 receptor in rat brain. Br J Pharmacol 117: 657-666.
30. 7 receptor antagonist. Br J Pharmacol 130: 539-548.
31. 7 heteroreceptor-mediated inhibition of [3H]serotonin release in raphe nuclei slices of the rat: evidence for a serotonergic-glutamatergic interaction. Neurochem Res 29: 1487-1497.
32. 7 receptor and disorders of the nervous system: an overview. Psychopharmacology (Berl) 206: 345-354.
33. 7 receptor knockout mice. Proc Natl Acad Sci USA 100: 1375-1380.
34. 7 receptor inhibition and inactivation induce antidepressantlike behavior and sleep pattern. Biol Psychiatry 58: 831-837.
35. 7 receptors to induce hypothermia in rodents. Eur J Pharmacol 487: 125-132.
36. 7 receptor research. Trends Pharmacol Sci 25: 481-486.
37. Hoyer D, Hannon JP, Martin GR. 2002. Molecular, pharmacological and functional diversity of 5-HT receptors. Pharmacol Biochem Behav 71: 533-554.
38. Hunsaker MR, Rosenberg JS, Kesner RP. 2008. The role of the dentate gyrus, CA3a, b, and CA3c for detecting spatial and environmental novelty Hippocampus 18: 1064-1073.
39. Jørgensen HS. 2007. Studies on the neuroendocrine role of serotonin. Dan Med Bull 54: 266-288.
40. Jovanovska A, Prosser RA. 2002. Translational and transcriptional inhibitors block serotonergic phase advances of the suprachiasmatic nucleus circadian pacemaker in vitro. J Biol Rhythms 17: 137-146.
41. Kandel ER. 2001. The molecular biology of memory storage: A dialogue between genes and synapses. Science 294: 1030-1038.
42. 7 receptor stimulation of GABAA receptor-activated current in cultured rat suprachiasmatic neurones. J Physiol 478: 67-73.
43. 7 receptor. J Med Chem 42: 533-535.
44. Kim JJ, Fanselow MS. 1992. Modality-specific retrograde amnesia of fear. Science 256: 675-677.
45. 7 receptor antagonist, also has functional activity at the dopamine D2 receptor. Eur J Pharmacol 449: 105-111.
46. 7 serotonin receptor mRNA expression with aging in rat brain. Mol Brain Res 79: 163-168.
47. Kvachnina E, Dumuis A, Wlodarczyk J, Renner U, Cochet M, Richter DW, Ponimaskin E. 2009. Constitutive G(s)-, but not G(12)-mediated activity of the 5-hydroxytryptamine 5-HT(7(a)) receptor is modulated by the palmitoylation of its C-terminal domain. Biochim Biophys Acta 1793: 1646-1655.
48. 7 receptor is coupled to Gα subunits of heterotrimeric G12-protein to regulate gene transcription and neuronal morphology. J Neurosci 25: 7821-7830.
49. 7 receptor agents: Structure-activity relationships and potential therapeutic applications in central nervous system disorders. Pharmacol Ther 129: 120-148.
50. Liy-Salmeron G, Meneses A. 2007. Role of 5-HT1-7 receptors in short- and long-term memory for an autoshaping task: Intrahippocampal manipulations. Brain Res 1147: 140-147.
51. 7) implicated in the regulation of mammalian circadian rhythms. Neuron 11: 449-458.
52. Luna-Munguia H, Manuel-Apolinar L, Rocha L, Meneses A. 2005. 5-HT1A receptor expression during memory formation. Psychopharmacology (Berl) 181: 309-318.
53. Mahgoub MA, Sara Y, Kavalali ET, Monteggia LM. 2006. Reciprocal interaction of serotonin and neuronal activity in regulation of cAMP-responsive element-dependent gene expression. J Pharmacol Exp Ther 317: 88-96.
54. Manuel-Apolinar L, Meneses A. 2004. 8-OH-DPAT facilitated memory consolidation and increased hippocampal and cortical cAMP production. Behav Brain Res 148: 179-184.
55. 7 receptors in the human brain using [3H]mesulergine: Comparison to other mammalian species. Br J Pharmacol 141: 92-104.
56. McGaugh JL, Izquierdo I. 2000. The contribution of pharmacology to research on the mechanisms of memory formation. Trends Pharmacol Sci 21: 208-210.
57. 7 receptor antagonists SB-269970 and DR 4004 in autoshaping Pavlovian/instrumental learning task. Behav Brain Res 155: 275-282.
58. Meneses A. 2007. Do serotonin(1-7) receptors modulate short and long-term memory? Neurobiol Learn Mem 87: 561-572.
59. 7 receptors in the facilitatory response induced by 8-OH-DPAT on learning consolidation. Behav Brain Res 121: 21-28.
60. Mengod G, Vilaró MT, Raurich A, López-Giménez JF, Cortés R, Palacios JM. 1996. 5-HT receptors in mammalian brain: receptor autoradiography and in situ hybridization studies of new ligands and newly identified receptors. Histochem J 28: 747-758.
61. Meyerhof W, Obermüller F, Fehr S, Richter D. 1993. A novel rat serotonin receptor: Primary structure, pharmacology, and expression pattern in distinct brain regions. DNA Cell Biol 12: 401-409.
62. Monsma FJ, Shen Y, Ward RP, Hamblin MW, Sibley DR. 1993. Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs. Mol Pharmacol 43: 320-327.
63. Morris RGM, Garrud P, Rawlins JNP, O'Keefe J. 1982. Place navigation impaired in rats with hippocampal lesions. Nature 297: 681-683.
64. 7 receptor regulation in the rat hypothalamus. Neuropsychopharmacology 21: 352-367.
65. 7 receptors in rat brain by immunocytochemistry, in situ hybridization, and agonist stimulated cFos expression. J Chem Neuroanat 21: 63-73.
66. O'Keefe J, Nadel L. 1978. The Hippocampus as a Cognitive Map. Oxford: Oxford University Press.
67. 7 receptor agonists and antagonists on cAMP accumulation during memory formation and amnesia. Behav Brain Res 195: 139-146.
68. 7 receptors. Behav Brain Res 202: 102-113.
69. 7 receptors during memory consolidation. Behav Brain Res 169: 83-92.
70. 7 receptor agonist AS 19 in an autoshaping learning task. Behav Brain Res 163: 136-140.
71. Phillips RG, LeDoux JE. 1992. Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. Behav Neurosci 106: 274-285.
72. Plassat JL, Amlaiky N, Hen R. 1993. Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase. Mol Pharmacol 44: 229-236.
73. 7 receptors in the micturition reflex in anaesthetized female rats. Br J Pharmacol 140: 53-60.
74. Recio P, Barahona MV, Orensanz LM, Bustamante S, Martínez AC, Benedito S, García-Sacristán A, Prieto D, Hernández M. 2009. 5-hydroxytryptamine induced relaxation in the pig urinary bladder neck. Br J Pharmacol 157: 271-280.
75. 7 receptors show specific impairments in contextual learning. Eur J Neurosci 19: 1913-1922.
76. Roth B, Craigo S, Choudhary M, Uluer A, Monsma FJ, Shen Y, Meltzer H, Sibley D. 1994. Binding of typical and atypical antipsychotic agents to 5- hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J Pharmacol Exp Ther 268: 1403-1410.
77. 7) activating cAMP formation. Proc Natl Acad Sci USA 90: 8547-8551.
78. Sacchetti B, Lorenzini CA, Baldi E, Bucherelli C, Roberto M, Tassoni G, Brunelli M. 2002. Time-dependent inhibition of hippocampal LTP in vitro following contextual fear conditioning in the rat. Eur J Neurosci 15: 143-150.
79. Sanders AE, Holtzer R, Lipton RB, Hall C, Verghese J. 2008. Egocentric and exocentric navigation skills in older adults. J Gerontol A Biol Sci Med Sci 63: 1356-1363.
80. 7 receptor is involved in allocentric spatial memory information processing. Behav Brain Res 202: 26-31.
81. 7 receptor as a mediator and modulator of antidepressant-like behavior. Behav Brain Res 209: 99-108.
82. Shen Y, Monsma FJ, Metcalf MA, Jose PA, Hamblin MW, Sibley DR. 1993. Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype. J Biol Chem 268: 18200-18204.
83. 7 Receptors. In Annu Reports in Medicinal Chemistry, Vol 43. New York: Academic Press. pp 25-42.
84. 7 and 5-HT1A receptors. Br J Pharmacol 128: 158-164.
85. 7 receptors. Curr. Drug Target CNS Neurol Disord 3: 81-90.
86. 7 receptors increase the excitability of rat hippocampal CA1 pyramidal neurons. Brain Res 993: 230-234.
87. To ZP, Bonhaus DW, Eglen RM, Jakeman LB. 1995. Characterization and distribution of putative 5-ht7 receptors in guinea-pig brain. Br J Pharmacol 115: 107-116.
88. 7 receptors in the human brain: A preliminary autoradiographic study using [3H]SB-269970. Neurosci Lett 367: 313-316.
89. Waeber C, Moskowitz MA. 1995. Autoradiographic visualisation of [3H]5-carboxamidotryptamine binding sites in the guinea pig and rat brain. Eur J Pharmacol 283: 31-46.
90. Witkin JM, Baez M, Yu J, Barton ME, Shannon HE. 2007. Constitutive deletion of the serotonin-7 (5-HT(7)) receptor decreases electrical and chemical seizure thresholds. Epilepsy Res 75: 39-45.
91. Wolfer DP, Stagljar-Bozicevic M, Errington ML, Lipp H. 1998. Spatial memory and learning in transgenic mice: Fact or artifact? News Physiol Sci 13: 118-123.
92. 7 receptor mRNA expression in the rat hippocampus. Neurosci Lett 309: 141-144.