-
1
-
-
0023724778
-
I kappa B: a specific inhibitor of the NF-kappa B transcription factor
-
Baeuerle PA, Baltimore D. I kappa B: a specific inhibitor of the NF-kappa B transcription factor. Science 1988;242:540-546.
-
(1988)
Science
, vol.242
, pp. 540-546
-
-
Baeuerle, P.A.1
Baltimore, D.2
-
2
-
-
0025304791
-
Purified human I kappa B can rapidly dissociate the complex of the NF-kappa B transcription factor with its cognate DNA
-
Zabel U, Baeuerle PA. Purified human I kappa B can rapidly dissociate the complex of the NF-kappa B transcription factor with its cognate DNA. Cell 1990;61:255-265.
-
(1990)
Cell
, vol.61
, pp. 255-265
-
-
Zabel, U.1
Baeuerle, P.A.2
-
3
-
-
84858744393
-
It takes two to tango: IkBs, the multifunctional partners of NF-κB
-
Hinz M, Arslan SC, Scheidereit C. It takes two to tango: IkBs, the multifunctional partners of NF-κB. Immunol Rev 2012;246:59-76.
-
(2012)
Immunol Rev
, vol.246
, pp. 59-76
-
-
Hinz, M.1
Arslan, S.C.2
Scheidereit, C.3
-
4
-
-
0027176524
-
Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B
-
Henkel T, Machleidt T, Alkalay I, Kronke M, Ben-Neriah Y, Baeuerle PA. Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B. Nature 1993;365:182-185.
-
(1993)
Nature
, vol.365
, pp. 182-185
-
-
Henkel, T.1
Machleidt, T.2
Alkalay, I.3
Kronke, M.4
Ben-Neriah, Y.5
Baeuerle, P.A.6
-
5
-
-
0028986075
-
Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation
-
Brown K, Gerstberger S, Carlson L, Franzoso G, Siebenlist U. Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation. Science 1995;267:1485-1488.
-
(1995)
Science
, vol.267
, pp. 1485-1488
-
-
Brown, K.1
Gerstberger, S.2
Carlson, L.3
Franzoso, G.4
Siebenlist, U.5
-
6
-
-
84858739354
-
Regulation of NFkB by ubiquitination and degradation of the IkBs
-
Kanarek N, Ben-Neriah Y. Regulation of NFkB by ubiquitination and degradation of the IkBs. Immunol Rev 2012;246:77-94.
-
(2012)
Immunol Rev
, vol.246
, pp. 77-94
-
-
Kanarek, N.1
Ben-Neriah, Y.2
-
7
-
-
0027168447
-
NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway
-
Sun SC, Ganchi PA, Ballard DW, Greene WC. NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway. Science 1993;259:1912-1915.
-
(1993)
Science
, vol.259
, pp. 1912-1915
-
-
Sun, S.C.1
Ganchi, P.A.2
Ballard, D.W.3
Greene, W.C.4
-
8
-
-
0028967819
-
Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B
-
Arenzana-Seisdedos F, Thompson J, Rodriguez MS, Bachelerie F, Thomas D, Hay RT. Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B. Mol Cell Biol 1995;15:2689-2696.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 2689-2696
-
-
Arenzana-Seisdedos, F.1
Thompson, J.2
Rodriguez, M.S.3
Bachelerie, F.4
Thomas, D.5
Hay, R.T.6
-
9
-
-
0032217268
-
The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation
-
Huxford T, Huang DB, Malek S, Ghosh G. The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation. Cell 1998;95:759-770.
-
(1998)
Cell
, vol.95
, pp. 759-770
-
-
Huxford, T.1
Huang, D.B.2
Malek, S.3
Ghosh, G.4
-
10
-
-
0030610362
-
A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB
-
DiDonato JA, Hayakawa M, Rothwarf DM, Zandi E, Karin M. A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB. Nature 1997;388:548-554.
-
(1997)
Nature
, vol.388
, pp. 548-554
-
-
DiDonato, J.A.1
Hayakawa, M.2
Rothwarf, D.M.3
Zandi, E.4
Karin, M.5
-
11
-
-
0031586174
-
Identification and characterization of an IkappaB kinase
-
Regnier CH, Song HY, Gao X, Goeddel DV, Cao Z, Rothe M. Identification and characterization of an IkappaB kinase. Cell 1997;90:373-383.
-
(1997)
Cell
, vol.90
, pp. 373-383
-
-
Regnier, C.H.1
Song, H.Y.2
Gao, X.3
Goeddel, D.V.4
Cao, Z.5
Rothe, M.6
-
12
-
-
0030611595
-
IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK
-
Woronicz JD, Gao X, Cao Z, Rothe M, Goeddel DV. IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK. Science 1997;278:866-869.
-
(1997)
Science
, vol.278
, pp. 866-869
-
-
Woronicz, J.D.1
Gao, X.2
Cao, Z.3
Rothe, M.4
Goeddel, D.V.5
-
13
-
-
0030613551
-
The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation
-
Zandi E, Rothwarf DM, Delhase M, Hayakawa M, Karin M. The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation. Cell 1997;91:243-252.
-
(1997)
Cell
, vol.91
, pp. 243-252
-
-
Zandi, E.1
Rothwarf, D.M.2
Delhase, M.3
Hayakawa, M.4
Karin, M.5
-
15
-
-
17944401842
-
Identification of the receptor component of the IkappaBalpha-ubiquitin ligase
-
Yaron A, et al. Identification of the receptor component of the IkappaBalpha-ubiquitin ligase. Nature 1998;396:590-594.
-
(1998)
Nature
, vol.396
, pp. 590-594
-
-
Yaron, A.1
-
16
-
-
38849199203
-
Shared principles in NF-kappaB signaling
-
Hayden MS, Ghosh S. Shared principles in NF-kappaB signaling. Cell 2008;132:344-362.
-
(2008)
Cell
, vol.132
, pp. 344-362
-
-
Hayden, M.S.1
Ghosh, S.2
-
17
-
-
84863338304
-
Ubiquitination in signaling to and activation of IKK
-
Chen ZJ. Ubiquitination in signaling to and activation of IKK. Immunol Rev 2012;246:95-106.
-
(2012)
Immunol Rev
, vol.246
, pp. 95-106
-
-
Chen, Z.J.1
-
18
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov R, Preston-Hurlburt P, Janeway CA Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997;388:394-397.
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway Jr., C.A.3
-
19
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene
-
Poltorak A, et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998;282:2085-2088.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
-
20
-
-
18244379306
-
Interactions of NF-kappaB with chromatin: the art of being at the right place at the right time
-
Natoli G, Saccani S, Bosisio D, Marazzi I. Interactions of NF-kappaB with chromatin: the art of being at the right place at the right time. Nat Immunol 2005;6:439-445.
-
(2005)
Nat Immunol
, vol.6
, pp. 439-445
-
-
Natoli, G.1
Saccani, S.2
Bosisio, D.3
Marazzi, I.4
-
21
-
-
77957253048
-
Control of NF-kappaB-dependent transcriptional responses by chromatin organization
-
Natoli G. Control of NF-kappaB-dependent transcriptional responses by chromatin organization. Cold Spring Harb Perspect Biol 2009;1:a000224.
-
(2009)
Cold Spring Harb Perspect Biol
, vol.1
-
-
Natoli, G.1
-
22
-
-
0033748023
-
Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages
-
Sanjabi S, Hoffmann A, Liou HC, Baltimore D, Smale ST. Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages. Proc Natl Acad Sci U S A 2000;97:12705-12710.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 12705-12710
-
-
Sanjabi, S.1
Hoffmann, A.2
Liou, H.C.3
Baltimore, D.4
Smale, S.T.5
-
23
-
-
0033451474
-
Rapid and selective remodeling of a positioned nucleosome during the induction of IL-12 p40 transcription
-
Weinmann AS, Plevy SE, Smale ST. Rapid and selective remodeling of a positioned nucleosome during the induction of IL-12 p40 transcription. Immunity 1999;11:665-675.
-
(1999)
Immunity
, vol.11
, pp. 665-675
-
-
Weinmann, A.S.1
Plevy, S.E.2
Smale, S.T.3
-
24
-
-
0033064319
-
Mapping DNA interaction sites of chromosomal proteins using immunoprecipitation and polymerase chain reaction
-
Hecht A, Grunstein M. Mapping DNA interaction sites of chromosomal proteins using immunoprecipitation and polymerase chain reaction. Methods Enzymol 1999;304:399-414.
-
(1999)
Methods Enzymol
, vol.304
, pp. 399-414
-
-
Hecht, A.1
Grunstein, M.2
-
25
-
-
0035908126
-
Two waves of nuclear factor kappaB recruitment to target promoters
-
Saccani S, Pantano S, Natoli G. Two waves of nuclear factor kappaB recruitment to target promoters. J Exp Med 2001;193:1351-1359.
-
(2001)
J Exp Med
, vol.193
, pp. 1351-1359
-
-
Saccani, S.1
Pantano, S.2
Natoli, G.3
-
26
-
-
32044439558
-
Selective and antagonistic functions of SWI/SNF and Mi-2beta nucleosome remodeling complexes during an inflammatory response
-
Ramirez-Carrozzi VR, et al. Selective and antagonistic functions of SWI/SNF and Mi-2beta nucleosome remodeling complexes during an inflammatory response. Genes Dev 2006;20:282-296.
-
(2006)
Genes Dev
, vol.20
, pp. 282-296
-
-
Ramirez-Carrozzi, V.R.1
-
27
-
-
79952539053
-
ATP-dependent chromatin remodeling: genetics, genomics and mechanisms
-
Hargreaves DC, Crabtree GR. ATP-dependent chromatin remodeling: genetics, genomics and mechanisms. Cell Res 2011;21:396-420.
-
(2011)
Cell Res
, vol.21
, pp. 396-420
-
-
Hargreaves, D.C.1
Crabtree, G.R.2
-
28
-
-
0035997356
-
ATP-dependent nucleosome remodeling
-
Becker PB, Horz W. ATP-dependent nucleosome remodeling. Annu Rev Biochem 2002;71:247-273.
-
(2002)
Annu Rev Biochem
, vol.71
, pp. 247-273
-
-
Becker, P.B.1
Horz, W.2
-
29
-
-
18644376284
-
IRF3 mediates a TLR3/TLR4-specific antiviral gene program
-
Doyle S, et al. IRF3 mediates a TLR3/TLR4-specific antiviral gene program. Immunity 2002;17:251-263.
-
(2002)
Immunity
, vol.17
, pp. 251-263
-
-
Doyle, S.1
-
31
-
-
45549090987
-
Class-specific regulation of pro-inflammatory genes by MyD88 pathways and IkappaBzeta
-
Kayama H, et al. Class-specific regulation of pro-inflammatory genes by MyD88 pathways and IkappaBzeta. J Biol Chem 2008;283:12468-12477.
-
(2008)
J Biol Chem
, vol.283
, pp. 12468-12477
-
-
Kayama, H.1
-
32
-
-
0032556894
-
Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA
-
Chen FE, Huang DB, Chen YQ, Ghosh G. Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA. Nature 1998;391:410-413.
-
(1998)
Nature
, vol.391
, pp. 410-413
-
-
Chen, F.E.1
Huang, D.B.2
Chen, Y.Q.3
Ghosh, G.4
-
33
-
-
5644289433
-
The histone octamer is invisible when NF-kappaB binds to the nucleosome
-
Angelov D, et al. The histone octamer is invisible when NF-kappaB binds to the nucleosome. J Biol Chem 2004;279:42374-42382.
-
(2004)
J Biol Chem
, vol.279
, pp. 42374-42382
-
-
Angelov, D.1
-
34
-
-
33747500567
-
A genomic code for nucleosome positioning
-
Segal E, et al. A genomic code for nucleosome positioning. Nature 2006;442:772-778.
-
(2006)
Nature
, vol.442
, pp. 772-778
-
-
Segal, E.1
-
35
-
-
62649085538
-
The DNA-encoded nucleosome organization of a eukaryotic genome
-
Kaplan N, et al. The DNA-encoded nucleosome organization of a eukaryotic genome. Nature 2009;458:362-366.
-
(2009)
Nature
, vol.458
, pp. 362-366
-
-
Kaplan, N.1
-
36
-
-
60349089645
-
Nucleosome positioning and gene regulation: advances through genomics
-
Jiang C, Pugh BF. Nucleosome positioning and gene regulation: advances through genomics. Nat Rev Genet 2009;10:161-172.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 161-172
-
-
Jiang, C.1
Pugh, B.F.2
-
37
-
-
79959557189
-
Determinants of nucleosome organization in primary human cells
-
Valouev A, Johnson SM, Boyd SD, Smith CL, Fire AZ, Sidow A. Determinants of nucleosome organization in primary human cells. Nature 2011;474:516-520.
-
(2011)
Nature
, vol.474
, pp. 516-520
-
-
Valouev, A.1
Johnson, S.M.2
Boyd, S.D.3
Smith, C.L.4
Fire, A.Z.5
Sidow, A.6
-
38
-
-
67649669255
-
A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling
-
Ramirez-Carrozzi VR, et al. A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling. Cell 2009;138:114-128.
-
(2009)
Cell
, vol.138
, pp. 114-128
-
-
Ramirez-Carrozzi, V.R.1
-
39
-
-
67649648237
-
Control of inducible gene expression by signal-dependent transcriptional elongation
-
Hargreaves DC, Horng T, Medzhitov R. Control of inducible gene expression by signal-dependent transcriptional elongation. Cell 2009;138:129-145.
-
(2009)
Cell
, vol.138
, pp. 129-145
-
-
Hargreaves, D.C.1
Horng, T.2
Medzhitov, R.3
-
40
-
-
79956330964
-
CpG islands and the regulation of transcription
-
Deaton AM, Bird A. CpG islands and the regulation of transcription. Genes Dev 2011;25:1010-1022.
-
(2011)
Genes Dev
, vol.25
, pp. 1010-1022
-
-
Deaton, A.M.1
Bird, A.2
-
41
-
-
77952908743
-
A large fraction of extragenic RNA pol II transcription sites overlap enhancers
-
De Santa F, et al. A large fraction of extragenic RNA pol II transcription sites overlap enhancers. PLoS Biol 2010;8:e1000384.
-
(2010)
PLoS Biol
, vol.8
-
-
De Santa, F.1
-
42
-
-
77951116072
-
CpG islands influence chromatin structure via the CpG-binding protein Cfp1
-
Thomson JP, et al. CpG islands influence chromatin structure via the CpG-binding protein Cfp1. Nature 2010;464:1082-1086.
-
(2010)
Nature
, vol.464
, pp. 1082-1086
-
-
Thomson, J.P.1
-
43
-
-
29244438472
-
CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex
-
Lee JH, Skalnik DG. CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex. J Biol Chem 2005;280:41725-41731.
-
(2005)
J Biol Chem
, vol.280
, pp. 41725-41731
-
-
Lee, J.H.1
Skalnik, D.G.2
-
44
-
-
77949971595
-
Selective transcription in response to an inflammatory stimulus
-
Smale ST. Selective transcription in response to an inflammatory stimulus. Cell 2010;140:833-844.
-
(2010)
Cell
, vol.140
, pp. 833-844
-
-
Smale, S.T.1
-
45
-
-
66149122282
-
Two modes of transcriptional activation at native promoters by NF-kappaB p65
-
van Essen D, Engist B, Natoli G, Saccani S. Two modes of transcriptional activation at native promoters by NF-kappaB p65. PLoS Biol 2009;7:e73.
-
(2009)
PLoS Biol
, vol.7
-
-
van Essen, D.1
Engist, B.2
Natoli, G.3
Saccani, S.4
-
46
-
-
77949977555
-
Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages
-
Ghisletti S, et al. Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages. Immunity 2010;32:317-328.
-
(2010)
Immunity
, vol.32
, pp. 317-328
-
-
Ghisletti, S.1
-
47
-
-
77952567987
-
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
-
Heinz S, et al. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol Cell 2010;38:576-589.
-
(2010)
Mol Cell
, vol.38
, pp. 576-589
-
-
Heinz, S.1
-
48
-
-
0028136726
-
Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages
-
Scott EW, Simon MC, Anastasi J, Singh H. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science 1994;265:1573-1577.
-
(1994)
Science
, vol.265
, pp. 1573-1577
-
-
Scott, E.W.1
Simon, M.C.2
Anastasi, J.3
Singh, H.4
-
49
-
-
0030069058
-
Terminal myeloid gene expression and differentiation requires the transcription factor PU.1
-
Simon MC, Olson M, Scott E, Hack A, Su G, Singh H. Terminal myeloid gene expression and differentiation requires the transcription factor PU.1. Curr Top Microbiol Immunol 1996;211:113-119.
-
(1996)
Curr Top Microbiol Immunol
, vol.211
, pp. 113-119
-
-
Simon, M.C.1
Olson, M.2
Scott, E.3
Hack, A.4
Su, G.5
Singh, H.6
-
50
-
-
0032146794
-
PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors
-
Nerlov C, Graf T. PU.1 induces myeloid lineage commitment in multipotent hematopoietic progenitors. Genes Dev 1998;12:2403-2412.
-
(1998)
Genes Dev
, vol.12
, pp. 2403-2412
-
-
Nerlov, C.1
Graf, T.2
-
51
-
-
78650210727
-
Bcl-6 and NF-κB cistromes mediate opposing regulation of the innate immune response
-
Barish GD, et al. Bcl-6 and NF-κB cistromes mediate opposing regulation of the innate immune response. Genes Dev 2010;24:2760-2765.
-
(2010)
Genes Dev
, vol.24
, pp. 2760-2765
-
-
Barish, G.D.1
-
52
-
-
77954928774
-
Maintaining cell identity through global control of genomic organization
-
Natoli G. Maintaining cell identity through global control of genomic organization. Immunity 2010;33:12-24.
-
(2010)
Immunity
, vol.33
, pp. 12-24
-
-
Natoli, G.1
-
53
-
-
77950339177
-
Conservation and regulatory associations of a wide affinity range of mouse transcription factor binding sites
-
Jaeger SA, Chan ET, Berger MF, Stottmann R, Hughes TR, Bulyk ML. Conservation and regulatory associations of a wide affinity range of mouse transcription factor binding sites. Genomics 2010;95:185-195.
-
(2010)
Genomics
, vol.95
, pp. 185-195
-
-
Jaeger, S.A.1
Chan, E.T.2
Berger, M.F.3
Stottmann, R.4
Hughes, T.R.5
Bulyk, M.L.6
-
54
-
-
77954954652
-
Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo
-
Wei GH, et al. Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo. EMBO J 2010;29:2147-2160.
-
(2010)
EMBO J
, vol.29
, pp. 2147-2160
-
-
Wei, G.H.1
-
55
-
-
33847076849
-
Chromatin modifications and their function
-
Kouzarides T. Chromatin modifications and their function. Cell 2007;128:693-705.
-
(2007)
Cell
, vol.128
, pp. 693-705
-
-
Kouzarides, T.1
-
56
-
-
0027465862
-
A positive role for histone acetylation in transcription factor access to nucleosomal DNA
-
Lee DY, Hayes JJ, Pruss D, Wolffe AP. A positive role for histone acetylation in transcription factor access to nucleosomal DNA. Cell 1993;72:73-84.
-
(1993)
Cell
, vol.72
, pp. 73-84
-
-
Lee, D.Y.1
Hayes, J.J.2
Pruss, D.3
Wolffe, A.P.4
-
57
-
-
0034610814
-
The language of covalent histone modifications
-
Strahl BD, Allis CD. The language of covalent histone modifications. Nature 2000;403:41-45.
-
(2000)
Nature
, vol.403
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
58
-
-
35848961668
-
How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers
-
Taverna SD, Li H, Ruthenburg AJ, Allis CD, Patel DJ. How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers. Nat Struct Mol Biol 2007;14:1025-1040.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 1025-1040
-
-
Taverna, S.D.1
Li, H.2
Ruthenburg, A.J.3
Allis, C.D.4
Patel, D.J.5
-
59
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
Barski A, et al. High-resolution profiling of histone methylations in the human genome. Cell 2007;129:823-837.
-
(2007)
Cell
, vol.129
, pp. 823-837
-
-
Barski, A.1
-
60
-
-
34547624303
-
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
-
Mikkelsen TS, et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 2007;448:553-560.
-
(2007)
Nature
, vol.448
, pp. 553-560
-
-
Mikkelsen, T.S.1
-
62
-
-
0036712454
-
Dynamic changes in histone H3 Lys 9 methylation occurring at tightly regulated inducible inflammatory genes
-
Saccani S, Natoli G. Dynamic changes in histone H3 Lys 9 methylation occurring at tightly regulated inducible inflammatory genes. Genes Dev 2002;16:2219-2224.
-
(2002)
Genes Dev
, vol.16
, pp. 2219-2224
-
-
Saccani, S.1
Natoli, G.2
-
63
-
-
0035839136
-
Translating the histone code
-
Jenuwein T, Allis CD. Translating the histone code. Science 2001;293:1074-1080.
-
(2001)
Science
, vol.293
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
64
-
-
0015296118
-
The distribution and turnover of labeled methyl groups in histone fractions of cultured mammalian cells
-
Byvoet P, Shepherd GR, Hardin JM, Noland BJ. The distribution and turnover of labeled methyl groups in histone fractions of cultured mammalian cells. Arch Biochem Biophys 1972;148:558-567.
-
(1972)
Arch Biochem Biophys
, vol.148
, pp. 558-567
-
-
Byvoet, P.1
Shepherd, G.R.2
Hardin, J.M.3
Noland, B.J.4
-
65
-
-
11144332565
-
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
-
Shi Y, et al. Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 2004;119:941-953.
-
(2004)
Cell
, vol.119
, pp. 941-953
-
-
Shi, Y.1
-
66
-
-
43249102851
-
Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease
-
Cloos PA, Christensen J, Agger K, Helin K. Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease. Genes Dev 2008;22:1115-1140.
-
(2008)
Genes Dev
, vol.22
, pp. 1115-1140
-
-
Cloos, P.A.1
Christensen, J.2
Agger, K.3
Helin, K.4
-
67
-
-
77956541159
-
A feed-forward circuit controlling inducible NF-kappaB target gene activation by promoter histone demethylation
-
van Essen D, Zhu Y, Saccani S. A feed-forward circuit controlling inducible NF-kappaB target gene activation by promoter histone demethylation. Mol Cell 2010;39:750-760.
-
(2010)
Mol Cell
, vol.39
, pp. 750-760
-
-
van Essen, D.1
Zhu, Y.2
Saccani, S.3
-
68
-
-
33847084602
-
Genome regulation by polycomb and trithorax proteins
-
Schuettengruber B, Chourrout D, Vervoort M, Leblanc B, Cavalli G. Genome regulation by polycomb and trithorax proteins. Cell 2007;128:735-745.
-
(2007)
Cell
, vol.128
, pp. 735-745
-
-
Schuettengruber, B.1
Chourrout, D.2
Vervoort, M.3
Leblanc, B.4
Cavalli, G.5
-
69
-
-
34548644772
-
The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing
-
De Santa F, Totaro MG, Prosperini E, Notarbartolo S, Testa G, Natoli G. The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing. Cell 2007;130:1083-1094.
-
(2007)
Cell
, vol.130
, pp. 1083-1094
-
-
De Santa, F.1
Totaro, M.G.2
Prosperini, E.3
Notarbartolo, S.4
Testa, G.5
Natoli, G.6
-
70
-
-
70350754328
-
Jmjd3 contributes to the control of gene expression in LPS-activated macrophages
-
De Santa F, et al. Jmjd3 contributes to the control of gene expression in LPS-activated macrophages. EMBO J 2009;28:3341-3352.
-
(2009)
EMBO J
, vol.28
, pp. 3341-3352
-
-
De Santa, F.1
-
71
-
-
77956954197
-
The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
-
Satoh T, et al. The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection. Nat Immunol 2010;11:936-944.
-
(2010)
Nat Immunol
, vol.11
, pp. 936-944
-
-
Satoh, T.1
-
72
-
-
70350435962
-
Epigenetic regulation of the alternatively activated macrophage phenotype
-
Ishii M, et al. Epigenetic regulation of the alternatively activated macrophage phenotype. Blood 2009;114:3244-3254.
-
(2009)
Blood
, vol.114
, pp. 3244-3254
-
-
Ishii, M.1
-
73
-
-
19944431570
-
Arginine methyltransferase CARM1 is a promoter-specific regulator of NF-kappaB-dependent gene expression
-
Covic M, et al. Arginine methyltransferase CARM1 is a promoter-specific regulator of NF-kappaB-dependent gene expression. EMBO J 2005;24:85-96.
-
(2005)
EMBO J
, vol.24
, pp. 85-96
-
-
Covic, M.1
-
74
-
-
70350719193
-
CARM1 but not its enzymatic activity is required for transcriptional coactivation of NF-kappaB-dependent gene expression
-
Jayne S, Rothgiesser KM, Hottiger MO. CARM1 but not its enzymatic activity is required for transcriptional coactivation of NF-kappaB-dependent gene expression. J Mol Biol 2009;394:485-495.
-
(2009)
J Mol Biol
, vol.394
, pp. 485-495
-
-
Jayne, S.1
Rothgiesser, K.M.2
Hottiger, M.O.3
-
75
-
-
0025872683
-
Rapid histone H3 phosphorylation in response to growth factors, phorbol esters, okadaic acid, and protein synthesis inhibitors
-
Mahadevan LC, Willis AC, Barratt MJ. Rapid histone H3 phosphorylation in response to growth factors, phorbol esters, okadaic acid, and protein synthesis inhibitors. Cell 1991;65:775-783.
-
(1991)
Cell
, vol.65
, pp. 775-783
-
-
Mahadevan, L.C.1
Willis, A.C.2
Barratt, M.J.3
-
76
-
-
0033200205
-
The nucleosomal response associated with immediate-early gene induction is mediated via alternative MAP kinase cascades: MSK1 as a potential histone H3/HMG-14 kinase
-
Thomson S, Clayton AL, Hazzalin CA, Rose S, Barratt MJ, Mahadevan LC. The nucleosomal response associated with immediate-early gene induction is mediated via alternative MAP kinase cascades: MSK1 as a potential histone H3/HMG-14 kinase. EMBO J 1999;18:4779-4793.
-
(1999)
EMBO J
, vol.18
, pp. 4779-4793
-
-
Thomson, S.1
Clayton, A.L.2
Hazzalin, C.A.3
Rose, S.4
Barratt, M.J.5
Mahadevan, L.C.6
-
77
-
-
0034679625
-
Phosphoacetylation of histone H3 on c-fos- and c-jun-associated nucleosomes upon gene activation
-
Clayton AL, Rose S, Barratt MJ, Mahadevan LC. Phosphoacetylation of histone H3 on c-fos- and c-jun-associated nucleosomes upon gene activation. EMBO J 2000;19:3714-3726.
-
(2000)
EMBO J
, vol.19
, pp. 3714-3726
-
-
Clayton, A.L.1
Rose, S.2
Barratt, M.J.3
Mahadevan, L.C.4
-
78
-
-
0036143654
-
p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment
-
Saccani S, Pantano S, Natoli G. p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment. Nat Immunol 2002;3:69-75.
-
(2002)
Nat Immunol
, vol.3
, pp. 69-75
-
-
Saccani, S.1
Pantano, S.2
Natoli, G.3
-
79
-
-
24944554790
-
Signaling pathways and genes that inhibit pathogen-induced macrophage apoptosis - CREB and NF-kappaB as key regulators
-
Park JM, et al. Signaling pathways and genes that inhibit pathogen-induced macrophage apoptosis - CREB and NF-kappaB as key regulators. Immunity 2005;23:319-329.
-
(2005)
Immunity
, vol.23
, pp. 319-329
-
-
Park, J.M.1
-
80
-
-
0037497184
-
A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression
-
Anest V, Hanson JL, Cogswell PC, Steinbrecher KA, Strahl BD, Baldwin AS. A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression. Nature 2003;423:659-663.
-
(2003)
Nature
, vol.423
, pp. 659-663
-
-
Anest, V.1
Hanson, J.L.2
Cogswell, P.C.3
Steinbrecher, K.A.4
Strahl, B.D.5
Baldwin, A.S.6
-
81
-
-
0038511129
-
Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression
-
Yamamoto Y, Verma UN, Prajapati S, Kwak YT, Gaynor RB. Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression. Nature 2003;423:655-659.
-
(2003)
Nature
, vol.423
, pp. 655-659
-
-
Yamamoto, Y.1
Verma, U.N.2
Prajapati, S.3
Kwak, Y.T.4
Gaynor, R.B.5
-
82
-
-
15944379896
-
Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation
-
Park KJ, Krishnan V, O'Malley BW, Yamamoto Y, Gaynor RB. Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation. Mol Cell 2005;18:71-82.
-
(2005)
Mol Cell
, vol.18
, pp. 71-82
-
-
Park, K.J.1
Krishnan, V.2
O'Malley, B.W.3
Yamamoto, Y.4
Gaynor, R.B.5
-
83
-
-
34247274248
-
Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin
-
Luo JL, et al. Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin. Nature 2007;446:690-694.
-
(2007)
Nature
, vol.446
, pp. 690-694
-
-
Luo, J.L.1
-
84
-
-
40649097065
-
IKKalpha is a critical coregulator of a Smad4-independent TGFbeta-Smad2/3 signaling pathway that controls keratinocyte differentiation
-
Descargues P, et al. IKKalpha is a critical coregulator of a Smad4-independent TGFbeta-Smad2/3 signaling pathway that controls keratinocyte differentiation. Proc Natl Acad Sci U S A 2008;105:2487-2492.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 2487-2492
-
-
Descargues, P.1
-
85
-
-
55949089769
-
The tumor suppressor activity of IKKalpha in stratified epithelia is exerted in part via the TGF-beta antiproliferative pathway
-
Marinari B, et al. The tumor suppressor activity of IKKalpha in stratified epithelia is exerted in part via the TGF-beta antiproliferative pathway. Proc Natl Acad Sci U S A 2008;105:17091-17096.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 17091-17096
-
-
Marinari, B.1
-
86
-
-
24644433852
-
Enhanced NF-kappaB activation and cellular function in macrophages lacking IkappaB kinase 1 (IKK1)
-
Li Q, et al. Enhanced NF-kappaB activation and cellular function in macrophages lacking IkappaB kinase 1 (IKK1). Proc Natl Acad Sci U S A 2005;102:12425-12430.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 12425-12430
-
-
Li, Q.1
-
87
-
-
17844386319
-
IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation
-
Lawrence T, Bebien M, Liu GY, Nizet V, Karin M. IKKalpha limits macrophage NF-kappaB activation and contributes to the resolution of inflammation. Nature 2005;434:1138-1143.
-
(2005)
Nature
, vol.434
, pp. 1138-1143
-
-
Lawrence, T.1
Bebien, M.2
Liu, G.Y.3
Nizet, V.4
Karin, M.5
-
88
-
-
78651479749
-
The genomic landscapes of inflammation
-
Natoli G, Ghisletti S, Barozzi I. The genomic landscapes of inflammation. Genes Dev 2011;25:101-106.
-
(2011)
Genes Dev
, vol.25
, pp. 101-106
-
-
Natoli, G.1
Ghisletti, S.2
Barozzi, I.3
-
89
-
-
80051988785
-
Hierarchies of NF-kappaB target-gene regulation
-
Smale ST. Hierarchies of NF-kappaB target-gene regulation. Nat Immunol 2011;12:689-694.
-
(2011)
Nat Immunol
, vol.12
, pp. 689-694
-
-
Smale, S.T.1
-
90
-
-
24144465889
-
Molecular determinants of crosstalk between nuclear receptors and toll-like receptors
-
Ogawa S, et al. Molecular determinants of crosstalk between nuclear receptors and toll-like receptors. Cell 2005;122:707-721.
-
(2005)
Cell
, vol.122
, pp. 707-721
-
-
Ogawa, S.1
-
91
-
-
78650806593
-
Suppression of inflammation by a synthetic histone mimic
-
Nicodeme E, et al. Suppression of inflammation by a synthetic histone mimic. Nature 2010;468:1119-1123.
-
(2010)
Nature
, vol.468
, pp. 1119-1123
-
-
Nicodeme, E.1
|