Transition from concerted to stepwise processes as a function of leaving group ability: Density functional theory and experimental study of lyoxide-promoted cleavages of phosphorothioate and phosphate triesters in water and methanol

Journal of Physical Organic Chemistry

Volumn 25, Issue 5, 2012, Pages 437-449

  Maxwell, Christopher I ^a   Liu, C Tony ^a   Neverov, Alexei A ^a   Mosey, Nicholas J ^a   Brown, Robert Stan ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

Br nsted; methanolysis and solvolysis; phosphate triesters; phosphorothioate triesters

Indexed keywords

COMPUTATIONAL DATA; CONTINUUM MEDIA; DENSITY FUNCTIONAL THEORY METHODS; EXPERIMENTAL STUDIES; LEAVING GROUPS; METHANOLYSIS; PHOSPHOROTHIOATES; RATE-LIMITING STEPS; SOLVOLYSES; TRIESTERS;

DENSITY FUNCTIONAL THEORY; SOLVENTS;

METHANOL;

EID: 84858627195     PISSN: 08943230     EISSN: 10991395     Source Type: Journal    
DOI: 10.1002/poc.1938     Document Type: Article

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