Inhibition of FAK prevents blister formation in the neonatal mouse model of pemphigus vulgaris

Experimental Dermatology

Volumn 21, Issue 4, 2012, Pages 254-259

  Gil, María P ^a   Modol, Teresa ^a   España, Agustín ^a   López Zabalza, María J ^a  

^a UNIVERSITY CLINIC OF NAVARRA   (Spain)

Author keywords

Acantholysis; Caspases; Focal adhesion kinase; Mouse model; Pemphigus vulgaris

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 METHYLPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; CASPASE 3; CASPASE 9; CASPASE INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; FI PF 573228; FOCAL ADHESION KINASE; FOCAL ADHESION KINASE INHIBITOR; IMMUNOGLOBULIN G; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; N [4 (3 BROMOANILINO) 6 QUINAZOLINYL] 2 BUTYNAMIDE; PROTEIN BAX; PROTEIN BCL 2; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL CELL; BLISTER; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; MOUSE; NEWBORN; NONHUMAN; PEMPHIGUS VULGARIS; PREMEDICATION; PROTEIN EXPRESSION; RECEPTOR UPREGULATION;

ACANTHOLYSIS; ANIMALS; ANIMALS, NEWBORN; BLISTER; CASPASES; DISEASE MODELS, ANIMAL; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; IMMUNIZATION, PASSIVE; IMMUNOGLOBULIN G; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; PEMPHIGUS; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SRC-FAMILY KINASES; TOR SERINE-THREONINE KINASES; TYROSINE;

EID: 84858451814     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/j.1600-0625.2012.01441.x     Document Type: Article

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