Differential caspase-9-dependent signaling pathway between tumor necrosis factor receptor- and Fas-mediated hepatocyte apoptosis in mice

Liver International

Volumn 26, Issue 1, 2006, Pages 137-146

  Imao, Motohiro ^a   Nagaki, Masahito ^a   Imose, Motoaki ^a   Moriwaki, Hisataka ^a  

^a GIFU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Caspase inhibitor; Cytochrome c; Cytokine; Hepatotoxicity; Mitochondria

Indexed keywords

BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 8; CASPASE 9; CASPASE 9 INHIBITOR; CYTOCHROME C; FAS ANTIGEN; GALACTOSAMINE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SYNTHESIS; HISTOPATHOLOGY; IN VIVO STUDY; LIVER CELL; LIVER INJURY; LIVER TOXICITY; MALE; MITOCHONDRION; MOUSE; MOUSE STRAIN; NONHUMAN; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; ANTIGENS, CD95; APOPTOSIS; BLOTTING, WESTERN; CASPASE 9; CASPASES; CYSTEINE PROTEINASE INHIBITORS; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; GALACTOSAMINE; HEPATOCYTES; IN SITU NICK-END LABELING; MALE; MICE; MICE, INBRED BALB C; RANDOM ALLOCATION; RECEPTORS, TUMOR NECROSIS FACTOR; SIGNAL TRANSDUCTION;

EID: 33645980974     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2005.01195.x     Document Type: Article

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