Assembly of focal adhesions: Progress, paradigms, and portents

Current Opinion in Cell Biology

Volumn 8, Issue 1, 1996, Pages 74-85

  Craig, Susan W ^a   Johnson, Robert P ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ACTIN BINDING PROTEIN; CELL RECEPTOR; EZRIN; VINCULIN;

BINDING SITE; CELL ADHESION; CELL MEMBRANE PERMEABILITY; EXTRACELLULAR MATRIX; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; REVIEW; SIGNAL TRANSDUCTION;

EID: 0030067021     PISSN: 09550674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0955-0674(96)80051-2     Document Type: Article

References (76)

1. Burridge K, Fath K, Kelly G, Nuckolls G, Turner C: Focal adhesions: transmembrane junctions between extracellular matrix and the cytoskeleton. Annu Rev Cell Biol 1988, 4:487-525.
2. Clark EA, Brugge JS: Integrins and signal transduction pathways: the road taken. Science 1995, 268:233-239.
3. Depasquale JA, Izzard CS: Evidence for an actin-containing cytoplasmic precursor of the focal contact and the timing of incorporation of vinculin at the focal contact J Cell Biol 1987, 105:2803-2809.
4. Plopper G, Ingber DE: Rapid induction and isolation of focal adhesion complexes. Biochem Biophys Res Commun 1993, 193:571-578.
5. Nobes C, Hall A: Regulation and function of the Rho subfamily of small GTPases. Curr Opin Genet Dev 1994, 4:77-81.
6. Yamada KM, Miyamoto S: Integrin transmembrane signaling and cytoskeletal control. Curr Opin Cell Biol 1995, 7:681-689.
7. Barry ST, Critchley DR: The rhoA-dependent assembly of focal adhesions in Swiss 3T3 cells is associated with increased tyrosine phosphorylation and the recruitment of both pp125FAK and protein kinase C-δ to focal adhesions. J Cell Sci 1994, 107:2033-2045.
8. Hall A: Small GTP-binding proteins and the regulation of the actin cytoskeleton. Ann Rev Cell Biol 1994, 10:31-54.
9. Kozma R, Ahmed S, Best A, Lim L: The ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts. Mol Cell Biol 1995, 15:1942-1952.
10. Nobes CD, Hall A: Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 1995, 81:53-62.
11. Chant J, Stowers L: GTPase cascades choreographing cellular behavior: movement, morphogenesis, and more. Cell 1995, 81:1-4.
12. Ridley AJ: Signal transduction through the GTP-binding proteins Rac and Rho. J Cell Sci 1994, Suppl 18:127-131.
13. Takai Y, Sasaki T, Tanaka K, Nakanishi H: Rho as a regulator of the cytoskeleton. Trends Biochem Sci 1995, 20:227-231.
14. Bokoch GM, Bohl BP, Chuang T-H: Guanine nucleotide exchange regulates membrane translocation of rac/rho GTP-binding proteins. J Biol Chem 1994, 269:31674-31679.
15. Moolenaar WH: Lysophosphatidic acid signalling. Curr Opin Cell Biol 1995, 7:203-210.
16. Moolenaar WH: Lysophosphatidic acid, a multifunctional phospholipid messenger. J Biol Chem 1995, 270:12949-12952.
17. Chrzanwska-Wodnicka M, Burridge K: Tyrosine phosphorylation is involved in reorganization of the actin cytoskeleton in response to serum or LPA stimulation. J Cell Sci 1994, 107:3643-3654.
18. Ridley AJ, Hall A: Signal transduction pathways regulating rho-mediated stress fibre formation: requirement for a tyrosine kinase. EMBO J 1994, 13:2600-2610.
19. Nobes CD, Hawkins P, Stephens L, Hall A: Activation of the small GTP-binding proteins rho and rac by growth factor receptors. J Cell Sci 1994, 108:225-233.
20. Zheng Y, Bagrodia S, Cerione RA: Activation of phophoinositide 3-kinase activity by Cdc42Hs binding to p85. J Biol Chem 1904, 269:18727-18730.
21. Peppelenbosch MP, Qiu R-G, De Vries-Smits AMM, Tertoolen LGJ, de Laat SW, McCormick F, Hall A, Symons MH, Bos JL: Rac mediates growth factor-induced arachidonic acid release. Cell 1995, 81:849-856.
22. Malcolm KC, Ross AH, Qiu R-G, Symons M, Exton JH: Activation of rat liver phospholipase D by the small GTP-binding protein RhoA. J Biol Chem 1994, 269:25951-25954.
23. Chong LD, Traynor-Kaplan A, Bokoch GM, Schwartz MA: The small GTP-binding protein rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells. Cell 1994, 79:507-513.
24. Zhang J, Benovic JL, Sugai M, Wetzker R, Gout I, Rittenhouse SE: Sequestration of a G-protein βγ subunit or ADP-ribosylation of rho can Inhibit thrombin-induced activation of platelet phosphoinositide 3-kinases. J Biol Chem 1995, 270:6589-6594.
25. 2 hydrolysis and regulation of phospholipase C isozymes. Curr Opin Cell Biol 1995, 7:183-189.
26. Reinhard J, Scheel AA, Diekmann D, Hall A, Ruppert C, Bahler M: A novel type of myosin implicated in signalling by rho family GTPases. EMBO J 1995, 14:697-704.
27. Ricahrdson A, Parsons JT: Signal transduction through integrins: a central role for focal adhesion kinase? Bioessays 1995, 17:229-236.
28. Kumagai N, Morii N, Fujisawa K, Nemoto Y, Narumiya S: ADP-ribosylation of rho p21 inhibits lysophosphatidic acid-induced protein tyrosine phosphorylation and phosphatidylinositol 3-kinase activation in cultured Swiss 3T3 cells. J Biol Chem 1993, 268:24535-24538.
29. src. Mol Cell Biol 1994, 14:1680-1688.
30. Calalb MB, Polte TR, Hanks SK: Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases. Mol Cell Biol 1995, 15:954-963.
31. Schlaepfer DD, Hanks SK, Hunter T, van der Geer P: Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 1994, 372:786-791.
32. Superti-Furga G, Courtneidge SA: Structure-function relationships In Src family and related protein tyrosine kinases. Bioessays 1995, 17:321-330.
33. Erpel T, Courtneidge SA: Src family protein tyrosine kinases and cellular signal transduction pathways. Curr Opin Cell Biol 1995, 7:176-182.
34. FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk. Mol Cell Biol 1995, 15:2635-2645.
35. Turner CE: Paxillin: a cytoskeletal target for tyrosine kinases. Bioessays 1994, 16:47-52.
36. Lo SH, Weisberg E, Chen LB: Tensin: a potential link between the cytoskeleton and signal transduction. Bioessays 1994, 16:817-823.
37. Petch LA, Bockholt SM, Bouton A, Parsons JT, Burridge K: Adhesion-induced tyrosine phosphorylation of the p130 Src substrate. J Cell Sci 1995, 108:1371-1379.
38. Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs. J Biol Chem 1995, 270:15398-15402.
39. Hildebrand JD, Schaller MD, Parsons JT: Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase. Mol Biol Cell 1995, 6:637-647.
40. FAK-binding region. J Cell Sci 1994, 107:1583-1591.
41. Lo SH, Janmey PA, Hartwig JH, Chen LB: Interactions of tensin with actin and identification of its three distinct actin-binding domains. J Cell Biol 1994, 125:1067-1075.
42. Chuang J-Z, Lin DC, Lin S: Molecular cloning, expression, and mapping of the high affinity actin-capping domain of chicken cardiac tensin. J Cell Biol 1995, 128:1095-1109.
43. Bellis SL, Miller JT, Turner CE: Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase. J Biol Chem 1995, 270:17437-17441.
44. Ilic D, Furuta Y, Kanazawa S, Takeda N, Sobue K, Nakatsuji N, Nomura S, Fujimoto J, Okada M, Yamamoto T, Aizawa S: Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-defident mice. Nature 1995, 377:539-544.
45. Chen H-C, Appeddu PA, Parsons JT, Hildebrand JD, Schaller MD, Guan J-L: Interaction of focal adhesion kinase with cytoskeletal protein talin. J Biol Chem 1995, 270:16995-16999.
46. Schaller MD, Otey CA, Hildebrand JD, Parsons JT: Focal adhesion kinase and paxillin bind to peptides mimicking β integrin cytoplasmic domains. J Cell Biol 1995, 130:1181-1187.
47. Katoh K, Masuda M, Kano Y, Jinguji Y, Fujiwara K: Focal adhesion proteins associated with apical stress fibers of human fibroblasts. Cell Motil Cytoskel 1995, 31:177-195.
48. FAK tyrosine kinase activity is not required for the assembly of F-actin stress fibres and focal adhesions in cultured mouse aortic smooth muscle cells. J Cell Sci 1995, 108:2381-2391.
49. Kaplan KB, Bibbins KB, Swedlow JR, Arnaud M, Morgan DO, Varmus HE: Association of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527. EMBO J 1994, 13:4745-4756.
50. Thomas SM, Soriano P, Imamoto A: Specific and redundant roles of Src and Fyn in organizing the cytoskeleton. Nature 1995, 376:267-271.
51. Stein PL, Vogel H, Soriano P: Combined deficiencies of Src, Fyn, and Yes tyrosine kinases in mutant mice. Genes Dev 1994, 8:1999-2007.
52. Serra-Pages C, Kedersha NL, Fazikas L, Medley Q, Debant A, Streuli M: The LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein colocalize at focal adhesions. EMBO J 1995, 14:2827-2838.
53. Plopper GE, McNamee HP, Dike LE, Bojanowski K, Ingber DE: Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex. Mol Biol Cell 1995, 6:1349-1365.
54. Miyamoto S, Akiyama SK, Yamada KM: Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function. Science 1995, 267:883-885.
55. Miyamoto S, Teramoto H, Coso OA, Gutkind JS, Burbelo PD, Akiyama SK, Yamada KM: Integrin function: molecular hierarchies of cytoskeletal and signaling molecules. J Cell Biol 1995, 131:791-805.
56. Tsukita S, Oishi K, Sato N, Sagara J, Kawai A, Tsukita SH: ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons. J Cell Biol 1994, 126:391-401.
57. Turunen O, Wahlstrom T, Vaheri A: Ezrin has a COOH-terminal actin-binding site that is conserved in the ezrin protein family. J Cell Biol 1994, 126:1445-1453.
58. Gary R, Bretscher A: Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site. Mol Biol Cell 1995, 6:1061-1075.
59. Isacke CM: The role of the cytoplasmic domain in regulating CD44 function. J Cell Sci 1994, 107:2353-2359.
60. Takeuchi K, Sato N, Kasahara H, Funayama N, Nagafuchi A, Yonemura S, Tsukita S, Tsukita SH: Perturbation of cell adhesion and microvilli formation by antisense oligonucleotides to ERM family members. J Cell Biol 1994, 125:1371-1384.
61. Redmond T, Tardif M, Zigmond SH: Induction of actin polymerization in permeabilized neutrophils. J Biol Chem 1994, 269:21657-21663.
62. Hartwig JH, Bokoch GM, Carpenter CL, Jammey PA, Taylor LA, Toker A, Stossel TP: Thrombin receptor ligation and activated Rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets. Cell 1995, 82:643-653.
63. FAK and paxillin in permeabilized Swiss 3T3 cells. J Biol Chem 1995, 270:6984-6990.
64. Li R, Zheng Y, Drubin DG: Regulation of cortical actin assembly during polarized cell growth in budding yeast J Cell Biol 1995, 128:599-615.
65. Menkel AK, Kroemker M, Bubeck P, Ronsiek M, Nikolai G, Jockusch BM: Characterization of a F-actin-binding domain in the cytoskeletal protein vinculin. J Cell Biol 1994, 126:1231-1240.
66. Johnson RP, Craig SW: F-actin binding site masked by the intramolecular association of vinculin head and tail domains. Nature 1995, 373:261-264.
67. Coll J-L, Ben-Ze'ev A, Ezzell RM, Rodriguez Fernandez JL, Baribault H, Oshima RG, Adamson ED: Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion. Proc Natl Acad Sci USA 1995, 92:9161-9165.
68. Volberg T, Geiger B, Kam Z, Pankov R, Simcha I, Sabanay H, Coll J-L, Adamson E, Ben-Ze'ev A: Focal adhesion formation by F9 embryonal carcinoma cells after vinculin gene disruption. J Cell Sci 1995, 108:2253-2260.
69. 2-terminal domain inhibits the cell extension activity of the COOH-terminal domain. J Cell Biol 1995, 128:1081-1093.
70. Rodriguez Fernandez JL, Geiger B, Salomon D, Ben-Ze'ev A: Suppression of vinculin expression by antisense transfection confers changes in cell morphology, motility, and anchorage-dependent growth of 3T3 cells. J Cell Biol 1993, 122:1285-1294.
71. Rodriguez Fernandez JL, Geiger B, Salomo N D, Ben-Ze'ev A: Overexpression of vinculin suppresses cell motility in BALB/c 3T3 cells. Cell Motil Cytoskeleton 1992, 22:127-134.
72. Johnson RP, Craig SW: An intramolecular association between the head and tail domains of vinculin modulates talin binding. J Biol Chem 1994, 269:12611-12619.
73. Johnson RP, Craig SW: The carboxy-terminal tail domain of vinculin contains a cryptic binding site for acidic phospholipids. Biochem Biophys Res Commun 1995, 210:159-164.
74. Magendantz M, Henry MD, Lander A, Solomon F: Interdomain interactions of radixin in vitro. J Biol Chem 1995, 270:25324-25327.
75. Henry MD, Gonzalez Agosti C, Solomon F: Molecular dissection of radixin: distinct and interdependent functions of the amino- and carboxy-terminal domains. J Cell Biol 1995, 129:1007-1022.
76. Vojtek AB, Cooper JA: Rho family members:activators of MAP kinase cascades. Cell 1995, 82:527-529.