메뉴 건너뛰기




Volumn 108, Issue 6, 2006, Pages 1965-1971

Rapamycin improves lymphoproliferative disease in murine autoimmune lymphoproliferative syndrome (ALPS)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; RAPAMYCIN;

EID: 33748681906     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2006-01-010124     Document Type: Article
Times cited : (83)

References (38)
  • 1
    • 0037279111 scopus 로고    scopus 로고
    • Autoimmune lymphoproliferative syndromes: Genetic defects of apoptosis pathways
    • Rieux-Laucat F, Le Deist F, Fischer A. Autoimmune lymphoproliferative syndromes: genetic defects of apoptosis pathways. Cell Death Differ. 2003;10:124-133.
    • (2003) Cell Death Differ , vol.10 , pp. 124-133
    • Rieux-Laucat, F.1    Le Deist, F.2    Fischer, A.3
  • 2
    • 20144380943 scopus 로고    scopus 로고
    • Unmasking Evans syndrome: T cell phenotype and apoptotic response reveal autoimmune lymphoproliferative syndrome (ALPS)
    • Teachey DT, Manno CS, Axsom KM, et al. Unmasking Evans syndrome: T cell phenotype and apoptotic response reveal autoimmune lymphoproliferative syndrome (ALPS). Blood. 2005;105:2443-2448.
    • (2005) Blood , vol.105 , pp. 2443-2448
    • Teachey, D.T.1    Manno, C.S.2    Axsom, K.M.3
  • 3
    • 0034536284 scopus 로고    scopus 로고
    • Autoimmune lymphoproliferative syndrome: A human disorder of abnormal lymphocyte survival
    • Bleesing JJ, Straus SE, Fleisher TA. Autoimmune lymphoproliferative syndrome: a human disorder of abnormal lymphocyte survival. Pediatr Clin North Am. 2000;47:1291-1310.
    • (2000) Pediatr Clin North Am , vol.47 , pp. 1291-1310
    • Bleesing, J.J.1    Straus, S.E.2    Fleisher, T.A.3
  • 4
    • 0019870366 scopus 로고
    • New antitumor substances of natural origin
    • Douros J, Suffness M. New antitumor substances of natural origin. Cancer Treat Rev. 1981;8:63-87.
    • (1981) Cancer Treat Rev , vol.8 , pp. 63-87
    • Douros, J.1    Suffness, M.2
  • 5
    • 0036094174 scopus 로고    scopus 로고
    • Induction of apoptosis and modulation of activation and effector function in T cells by immunosuppressive drugs
    • Strauss G, Osen W, Debatin KM. Induction of apoptosis and modulation of activation and effector function in T cells by immunosuppressive drugs. Clin Exp Immunol. 2002;128:255-266.
    • (2002) Clin Exp Immunol , vol.128 , pp. 255-266
    • Strauss, G.1    Osen, W.2    Debatin, K.M.3
  • 6
    • 0345166113 scopus 로고    scopus 로고
    • Rapamycin is active against B-precursor leukemia in vitro and in vivo, an effect that is modulated by IL-7-mediated signaling
    • Brown VI, Fang J, Alcorn K, et al. Rapamycin is active against B-precursor leukemia in vitro and in vivo, an effect that is modulated by IL-7-mediated signaling. Proc Natl Acad Sci U S A. 2003;100:15113-15118.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 15113-15118
    • Brown, V.I.1    Fang, J.2    Alcorn, K.3
  • 7
    • 0345059209 scopus 로고    scopus 로고
    • An inherited disorder of lymphocyte apoptosis: The autoimmune lymphoproliferative syndrome
    • Straus SE, Sneller M, Lenardo MJ, Puck JM, Strober W. An inherited disorder of lymphocyte apoptosis: the autoimmune lymphoproliferative syndrome. Ann Intern Med. 1999;130:591-601.
    • (1999) Ann Intern Med , vol.130 , pp. 591-601
    • Straus, S.E.1    Sneller, M.2    Lenardo, M.J.3    Puck, J.M.4    Strober, W.5
  • 8
    • 22244491316 scopus 로고    scopus 로고
    • A new three-dimensional ultrasound microimaging technology for preclinical studies using a transgenic prostate cancer mouse model
    • Wirtzfeld LA, Wu G, Bygrave M, et al. A new three-dimensional ultrasound microimaging technology for preclinical studies using a transgenic prostate cancer mouse model. Cancer Res. 2005;65:6337-6345.
    • (2005) Cancer Res , vol.65 , pp. 6337-6345
    • Wirtzfeld, L.A.1    Wu, G.2    Bygrave, M.3
  • 9
    • 0036334807 scopus 로고    scopus 로고
    • A composite picture of TcR alpha/beta(+) CD4(-)CD8(-) T cells (alpha/beta-DNTCs) in humans with autoimmune lymphoproliferative syndrome
    • Bleesing JJ, Brown MR, Novicio C, et al. A composite picture of TcR alpha/beta(+) CD4(-)CD8(-) T cells (alpha/beta-DNTCs) in humans with autoimmune lymphoproliferative syndrome. Clin Immunol. 2002;104:21-30.
    • (2002) Clin Immunol , vol.104 , pp. 21-30
    • Bleesing, J.J.1    Brown, M.R.2    Novicio, C.3
  • 10
    • 20044368060 scopus 로고    scopus 로고
    • Use of mycophenolate mofetil for chronic, refractory immune cytopenias in children with autoimmune lymphoproliferative syndrome
    • Rao VK, Dugan F, Dale JK, et al. Use of mycophenolate mofetil for chronic, refractory immune cytopenias in children with autoimmune lymphoproliferative syndrome. Br J Haematol. 2005;129:534-538.
    • (2005) Br J Haematol , vol.129 , pp. 534-538
    • Rao, V.K.1    Dugan, F.2    Dale, J.K.3
  • 11
    • 0033228167 scopus 로고    scopus 로고
    • Mycophenolate mofetil ameliorates perivascular T lymphocyte inflammation and reduces the double-negative T cell population in SLE-prone MRLlpr/lpr mice
    • Jonsson CA, Erlandsson M, Svensson L, Molne J, Carlsten H. Mycophenolate mofetil ameliorates perivascular T lymphocyte inflammation and reduces the double-negative T cell population in SLE-prone MRLlpr/lpr mice. Cell Immunol. 1999;197:136-144.
    • (1999) Cell Immunol , vol.197 , pp. 136-144
    • Jonsson, C.A.1    Erlandsson, M.2    Svensson, L.3    Molne, J.4    Carlsten, H.5
  • 12
    • 30344449766 scopus 로고    scopus 로고
    • 15-Deoxyspergualin and cyclophosphamide, but not mycophenolate mofetil, prolong survival and attenuate renal disease in a murine model of ANCA-associated crescentic nephritis
    • Birck R, Newman M, Braun C, et al. 15-Deoxyspergualin and cyclophosphamide, but not mycophenolate mofetil, prolong survival and attenuate renal disease in a murine model of ANCA-associated crescentic nephritis. Nephrol Dial Transplant. 2006;21:58-63.
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 58-63
    • Birck, R.1    Newman, M.2    Braun, C.3
  • 13
    • 31544443832 scopus 로고    scopus 로고
    • The mTOR inhibitor CCI-779 induces apoptosis and inhibits growth in preclinical models of primary adult human ALL
    • Teachey DT, Obzut DA, Cooperman J, et al. The mTOR inhibitor CCI-779 induces apoptosis and inhibits growth in preclinical models of primary adult human ALL. Blood. 2005;107:1149-1155.
    • (2005) Blood , vol.107 , pp. 1149-1155
    • Teachey, D.T.1    Obzut, D.A.2    Cooperman, J.3
  • 14
    • 4344610451 scopus 로고    scopus 로고
    • Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity
    • Huang S, Shu L, Easton J, et al. Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity. J Biol Chem. 2004;279:36490-36496.
    • (2004) J Biol Chem , vol.279 , pp. 36490-36496
    • Huang, S.1    Shu, L.2    Easton, J.3
  • 15
    • 0027143640 scopus 로고
    • Mature CD4+ T lymphocytes from MRL/lpr mice are resistant to receptor-mediated tolerance and apoptosis
    • Bossu P, Singer GG, Andres P, Ettinger R, Marshak-Rothstein A, Abbas AK. Mature CD4+ T lymphocytes from MRL/lpr mice are resistant to receptor-mediated tolerance and apoptosis. J Immunol. 1993;151:7233-7239.
    • (1993) J Immunol , vol.151 , pp. 7233-7239
    • Bossu, P.1    Singer, G.G.2    Andres, P.3    Ettinger, R.4    Marshak-Rothstein, A.5    Abbas, A.K.6
  • 16
    • 0034876118 scopus 로고    scopus 로고
    • TcR-alpha/beta(+) CD4(-)CD8(-) T cells in humans with the autoimmune lymphoproliferative syndrome express a novel CD45 isoform that is analogous to murine B220 and represents a marker of altered O-glycan biosynthesis
    • Bleesing JJ, Brown MR, Dale JK, et al. TcR-alpha/beta(+) CD4(-)CD8(-) T cells in humans with the autoimmune lymphoproliferative syndrome express a novel CD45 isoform that is analogous to murine B220 and represents a marker of altered O-glycan biosynthesis. Clin Immunol. 2001;100:314-324.
    • (2001) Clin Immunol , vol.100 , pp. 314-324
    • Bleesing, J.J.1    Brown, M.R.2    Dale, J.K.3
  • 17
    • 20144388310 scopus 로고    scopus 로고
    • Isolation and characterization of human antigen-specific TCR alpha beta+ CD4(-)CD8- Double-negative regulatory T cells
    • Fischer K, Voelkl S, Heymann J, et al. Isolation and characterization of human antigen-specific TCR alpha beta+ CD4(-)CD8- double-negative regulatory T cells. Blood. 2005;105:2828-2835.
    • (2005) Blood , vol.105 , pp. 2828-2835
    • Fischer, K.1    Voelkl, S.2    Heymann, J.3
  • 18
    • 0027336411 scopus 로고
    • Distinctive expression of lprcg in the heterozygous state on different genetic backgrounds
    • Ogata Y, Kimura M, Shimada K, et al. Distinctive expression of lprcg in the heterozygous state on different genetic backgrounds. Cell Immunol. 1993;148:91-102.
    • (1993) Cell Immunol , vol.148 , pp. 91-102
    • Ogata, Y.1    Kimura, M.2    Shimada, K.3
  • 20
    • 0041662261 scopus 로고    scopus 로고
    • Pharmacodynamic evaluation of CCI-779, an inhibitor of mTOR, in cancer patients
    • Peralba JM, DeGraffenried L, Friedrichs W, et al. Pharmacodynamic evaluation of CCI-779, an inhibitor of mTOR, in cancer patients. Clin Cancer Res. 2003;9:2887-2892.
    • (2003) Clin Cancer Res , vol.9 , pp. 2887-2892
    • Peralba, J.M.1    DeGraffenried, L.2    Friedrichs, W.3
  • 21
    • 0033143385 scopus 로고    scopus 로고
    • How Bad phosphorylation is good for survival
    • Downward J. How Bad phosphorylation is good for survival. Nat Cell Biol. 1999;1:E33-E35.
    • (1999) Nat Cell Biol , vol.1
    • Downward, J.1
  • 22
    • 27744539859 scopus 로고    scopus 로고
    • mTOR-dependent suppression of protein phosphatase 2A is critical for phospholipase D survival signals in human breast cancer cells
    • Hui L, Rodrik V, Pielak RM, Knirr S, Zheng Y, Foster DA. mTOR-dependent suppression of protein phosphatase 2A is critical for phospholipase D survival signals in human breast cancer cells. J Biol Chem. 2005;280:35829-35835.
    • (2005) J Biol Chem , vol.280 , pp. 35829-35835
    • Hui, L.1    Rodrik, V.2    Pielak, R.M.3    Knirr, S.4    Zheng, Y.5    Foster, D.A.6
  • 23
    • 0036241265 scopus 로고    scopus 로고
    • Newer immunosuppressive drugs: Their potential role in rheumatoid arthritis therapy
    • Drosos AA. Newer immunosuppressive drugs: their potential role in rheumatoid arthritis therapy. Drugs. 2002;62:891-907.
    • (2002) Drugs , vol.62 , pp. 891-907
    • Drosos, A.A.1
  • 24
    • 0035165578 scopus 로고    scopus 로고
    • Rapamycin in transplantation: A review of the evidence
    • Saunders RN, Metcalfe MS, Nicholson ML. Rapamycin in transplantation: a review of the evidence. Kidney Int. 2001;59:3-16.
    • (2001) Kidney Int , vol.59 , pp. 3-16
    • Saunders, R.N.1    Metcalfe, M.S.2    Nicholson, M.L.3
  • 25
    • 0026030568 scopus 로고
    • Chemistry and biology of immunophilins and their immunosupressive ligands
    • Schreiber SL. Chemistry and biology of immunophilins and their immunosupressive ligands. Science. 1991;251:283-287.
    • (1991) Science , vol.251 , pp. 283-287
    • Schreiber, S.L.1
  • 26
    • 0034636055 scopus 로고    scopus 로고
    • The immunosupressive macrolide RAD inhibits growth of human Epstein-Barr virus-transformed B lymphocytes in vitro and in vivo: A potential approach to prevention and treatment of posttransplant lymphoproliferative disorders
    • Majewski M, Korecka M, Kossev P, et al. The immunosupressive macrolide RAD inhibits growth of human Epstein-Barr virus-transformed B lymphocytes in vitro and in vivo: a potential approach to prevention and treatment of posttransplant lymphoproliferative disorders. Proc Natl Acad Sci U S A. 2000;97:4285-4290.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 4285-4290
    • Majewski, M.1    Korecka, M.2    Kossev, P.3
  • 27
    • 0024976525 scopus 로고
    • Rapamycin for immunosuppression in organ allografting
    • Calne RY, Collier DS, Lim S, et al. Rapamycin for immunosuppression in organ allografting [letter]. Lancet. 1989;2:227.
    • (1989) Lancet , vol.2 , pp. 227
    • Calne, R.Y.1    Collier, D.S.2    Lim, S.3
  • 28
    • 0034810020 scopus 로고    scopus 로고
    • Safety and efficacy of TOR inhibitors in pediatric renal transplant recipients
    • Ettenger RB, Grimm EM. Safety and efficacy of TOR inhibitors in pediatric renal transplant recipients. Am J Kidney Dis. 2001;38:S22-S28.
    • (2001) Am J Kidney Dis , vol.38
    • Ettenger, R.B.1    Grimm, E.M.2
  • 29
    • 0033040508 scopus 로고    scopus 로고
    • Treatment of refractory Evans' syndrome with cyclosporine and prednisone
    • Ucar B, Akgun N, Aydogdu SD, Kirel B, Idem S. Treatment of refractory Evans' syndrome with cyclosporine and prednisone. Pediatr Int. 1999;41:104-107.
    • (1999) Pediatr Int , vol.41 , pp. 104-107
    • Ucar, B.1    Akgun, N.2    Aydogdu, S.D.3    Kirel, B.4    Idem, S.5
  • 30
    • 0028217271 scopus 로고
    • Treatment of refractory Evans syndrome with alternate-day cyclosporine and prednisone
    • Rackoff WR, Manno CS. Treatment of refractory Evans syndrome with alternate-day cyclosporine and prednisone. Am J Pediatr Hematol Oncol. 1994;16:156-159.
    • (1994) Am J Pediatr Hematol Oncol , vol.16 , pp. 156-159
    • Rackoff, W.R.1    Manno, C.S.2
  • 33
    • 0032526253 scopus 로고    scopus 로고
    • A blinded, long-term, randomized multicenter study of mycophenolate mofetil in cadaveric renal transplantation: Results at three years
    • Tricontinental Mycophenolate Mofetil Renal Transplantation Study Group
    • Mathew TH. A blinded, long-term, randomized multicenter study of mycophenolate mofetil in cadaveric renal transplantation: results at three years. Tricontinental Mycophenolate Mofetil Renal Transplantation Study Group. Transplantation. 1998;65:1450-1454.
    • (1998) Transplantation , vol.65 , pp. 1450-1454
    • Mathew, T.H.1
  • 34
    • 0036667322 scopus 로고    scopus 로고
    • Cytoplasmic micro heavy chain confers sensitivity to dexamethasone- induced apoptosis in early B-lineage acute lymphoblastic leukemia
    • Kim JM, Fang J, Rheingold S, et al. Cytoplasmic micro heavy chain confers sensitivity to dexamethasone-induced apoptosis in early B-lineage acute lymphoblastic leukemia. Cancer Res. 2002;62:4212-4216.
    • (2002) Cancer Res , vol.62 , pp. 4212-4216
    • Kim, J.M.1    Fang, J.2    Rheingold, S.3
  • 35
    • 4644304217 scopus 로고    scopus 로고
    • Expression of the glucocorticoid receptor from the 1A promoter correlates with T lymphocyte sensitivity to glucocorticoid-induced cell death
    • Purton JF, Monk JA, Liddicoat DR, et al. Expression of the glucocorticoid receptor from the 1A promoter correlates with T lymphocyte sensitivity to glucocorticoid-induced cell death. J Immunol. 2004;173:3816-3824.
    • (2004) J Immunol , vol.173 , pp. 3816-3824
    • Purton, J.F.1    Monk, J.A.2    Liddicoat, D.R.3
  • 36
    • 20444450184 scopus 로고    scopus 로고
    • Mutagenic and cytotoxic effects of immunosuppressive drugs on human lymphocyte cultures
    • Oliveira VD, Zankl H, Rath T. Mutagenic and cytotoxic effects of immunosuppressive drugs on human lymphocyte cultures. Exp Clin Transplant. 2004;2:273-279.
    • (2004) Exp Clin Transplant , vol.2 , pp. 273-279
    • Oliveira, V.D.1    Zankl, H.2    Rath, T.3
  • 37
    • 0036223531 scopus 로고    scopus 로고
    • Reversion of autoimmune lymphoproliferative syndrome with an antimalarial drug: Preliminary results of a clinical cohort study and molecular observations
    • van der Werff Ten Bosch J, Schotte P, Ferster A, et al. Reversion of autoimmune lymphoproliferative syndrome with an antimalarial drug: preliminary results of a clinical cohort study and molecular observations. Br J Haematol. 2002;117:176-188.
    • (2002) Br J Haematol , vol.117 , pp. 176-188
    • Van Der Werff Ten Bosch, J.1    Schotte, P.2    Ferster, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.