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Volumn 21, Issue 1, 2012, Pages 44-52

Hollow out-of-plane polymer microneedles made by solvent casting for transdermal drug delivery

Author keywords

BioMEMS; drug delivery; hollow out of plane polymer microneedles; solvent cast microstructures

Indexed keywords

COMPRESSIVE LOADS; FABRICATION TECHNIQUE; MASS FABRICATION; MECHANICAL TESTS; MICRONEEDLES; OUT-OF-PLANE; POLYMER LAYERS; SKIN PENETRATION; SKIN SAMPLES; SOLID STRUCTURES; SOLVENT CAST; SOLVENT CASTING; SOLVENT EVAPORATION; TRANSDERMAL DRUG DELIVERY;

EID: 84858448968     PISSN: 10577157     EISSN: None     Source Type: Journal    
DOI: 10.1109/JMEMS.2011.2174429     Document Type: Article
Times cited : (40)

References (53)
  • 1
    • 55749108348 scopus 로고    scopus 로고
    • Transdermal drug delivery
    • Nov.
    • M. R. Prausnitz and R. Langer, "Transdermal drug delivery," Nat. Biotechnol., vol. 26, no. 11, pp. 1261-1268, Nov. 2008.
    • (2008) Nat. Biotechnol. , vol.26 , Issue.11 , pp. 1261-1268
    • Prausnitz, M.R.1    Langer, R.2
  • 2
    • 0032102453 scopus 로고    scopus 로고
    • Skin adhesives and skin adhesion. 1. Transdermal drug delivery systems
    • DOI 10.1016/S0142-9612(98)00020-9, PII S0142961298000209
    • S. Venkatraman and R. Gale, "Skin adhesives and skin adhesion: 1. Transdermal drug delivery systems," Biomaterials, vol. 19, no. 13, pp. 1119-1136, Jun. 1998. (Pubitemid 28388829)
    • (1998) Biomaterials , vol.19 , Issue.13 , pp. 1119-1136
    • Venkatraman, S.1    Gale, R.2
  • 7
    • 0034282141 scopus 로고    scopus 로고
    • Transdermal drug delivery: Overcoming the skin's barrier function
    • Sep.
    • N. Y. N. Kalia and R. H. Guy, "Transdermal drug delivery: Overcoming the skin's barrier function," Pharm. Sci. Technol. Today, vol. 3, no. 9, pp. 318-326, Sep. 2000.
    • (2000) Pharm. Sci. Technol. Today , vol.3 , Issue.9 , pp. 318-326
    • Kalia, N.Y.N.1    Guy, R.H.2
  • 8
    • 0034331266 scopus 로고    scopus 로고
    • Transdermal drug delivery systems and skin sensitivity reactions: Incidence and management
    • Nov./Dec.
    • M. Murphy and A. J. Carmichael, "Transdermal drug delivery systems and skin sensitivity reactions: Incidence and management," Amer. J. Clin. Dermatol., vol. 1, no. 6, pp. 361-368, Nov./Dec. 2000.
    • (2000) Amer. J. Clin. Dermatol. , vol.1 , Issue.6 , pp. 361-368
    • Murphy, M.1    Carmichael, A.J.2
  • 9
    • 17444403584 scopus 로고    scopus 로고
    • Clinical microneedle injection of methyl nicotinate: Stratum corneum penetration
    • DOI 10.1111/j.1600-0846.2005.00107.x
    • R. K. Sivamani, B. Stoeber, G. C. Wu, H. Zhai, D. Liepmann, and H. Maibach, "Clinical microneedle injection of methyl nicotinate: Stratum corneum penetration," Skin Res. Technol., vol. 11, no. 2, pp. 152-156, May 2005. (Pubitemid 40542856)
    • (2005) Skin Research and Technology , vol.11 , Issue.2 , pp. 152-156
    • Sivamani, R.K.1    Stoeber, B.2    Wu, G.C.3    Zhai, H.4    Liepmann, D.5    Maibach, H.6
  • 11
    • 55249125056 scopus 로고    scopus 로고
    • Effect of microneedle design on pain in human volunteers
    • Sep.
    • H. S. Gill, D. D. Denson, B. A. Burris, and M. R. Prausnitz, "Effect of microneedle design on pain in human volunteers," Clin. J. Pain, vol. 24, no. 7, pp. 585-594, Sep. 2008.
    • (2008) Clin. J. Pain , vol.24 , Issue.7 , pp. 585-594
    • Gill, H.S.1    Denson, D.D.2    Burris, B.A.3    Prausnitz, M.R.4
  • 12
    • 22444434334 scopus 로고    scopus 로고
    • Arrays of hollow out-of-plane microneedles for drug delivery
    • DOI 10.1109/JMEMS.2005.844843
    • B. Stoeber and D. Liepmann, "Arrays of hollow out-of-plane microneedles for drug delivery," J. Micorelectromech. Syst., vol. 14, no. 3, pp. 472-479, Jun. 2005. (Pubitemid 41005066)
    • (2005) Journal of Microelectromechanical Systems , vol.14 , Issue.3 , pp. 472-479
    • Stoeber, B.1    Liepmann, D.2
  • 14
    • 0031852494 scopus 로고    scopus 로고
    • Microfabricated microneedles: A novel approach to transdermal drug delivery
    • DOI 10.1021/js980042+
    • S. Henry, D. V. Mcallister, M. G. Allen, and M. R. Prausnitz, "Microfabricated microneedles: A novel approach to transdermal drug delivery," J. Pharm. Sci., vol. 87, no. 8, pp. 922-925, Aug. 1998. (Pubitemid 28381247)
    • (1998) Journal of Pharmaceutical Sciences , vol.87 , Issue.8 , pp. 922-925
    • Henry, S.1    McAllister, D.V.2    Allen, M.G.3    Prausnitz, M.R.4
  • 16
    • 0036105150 scopus 로고    scopus 로고
    • Improved genetic immunization via micromechanical disruption of skin-barrier function and targeted epidermal delivery
    • DOI 10.1038/nm0402-415
    • J. A. Mikszta, J. B. Alarcon, J. M. Brittingham, D. E. Sutter, R. J. Pettis, and N. G. Harvey, "Improved genetic immunization via micromechanical disruption of skinbarrier function and targeted epidermal delivery," Nat. Med., vol. 8, no. 4, pp. 415-419, Apr. 2002. (Pubitemid 34407039)
    • (2002) Nature Medicine , vol.8 , Issue.4 , pp. 415-419
    • Mikszta, J.A.1    Alarcon, J.B.2    Brittingham, J.M.3    Sutter, D.E.4    Pettis, R.J.5    Harvey, N.G.6
  • 19
    • 33744532495 scopus 로고    scopus 로고
    • Microfabricated hollow microneedle array using ICP etcher
    • DOI 10.1088/1742-6596/34/1/187
    • J. Ji, F. E. H. Tay, and J. Miao, "Microfabricated hollow microneedle array using ICP etcher," J. Phys., Conf. Ser., vol. 34, no. 34, pp. 1132-1136, May 2006. (Pubitemid 43812577)
    • (2006) Journal of Physics: Conference Series , vol.34 , Issue.1 , pp. 1132-1136
    • Ji, J.1    Tay, F.E.H.2    Miao, J.3
  • 20
    • 0037871729 scopus 로고    scopus 로고
    • Side-opened out-of-plane microneedles for microfluidic transdermal liquid transfer
    • Jun.
    • P. Griss and G. Stemme, "Side-opened out-of-plane microneedles for microfluidic transdermal liquid transfer," J. Micorelectromech. Syst., vol. 12, no. 3, pp. 296-301, Jun. 2003.
    • (2003) J. Micorelectromech. Syst. , vol.12 , Issue.3 , pp. 296-301
    • Griss, P.1    Stemme, G.2
  • 21
    • 4344666269 scopus 로고    scopus 로고
    • Microneedle array for transdermal biological fluid extraction and in situ analysis
    • Sep.
    • E. V. Mukerjee, S. D. Collins, R. R. Isseroff, and R. L. Smith, "Microneedle array for transdermal biological fluid extraction and in situ analysis," Sens. Actuators A, Phys., vol. 114, no. 2/3, pp. 267-275, Sep. 2004.
    • (2004) Sens. Actuators A, Phys. , vol.114 , Issue.2-3 , pp. 267-275
    • Mukerjee, E.V.1    Collins, S.D.2    Isseroff, R.R.3    Smith, R.L.4
  • 22
    • 9744225863 scopus 로고    scopus 로고
    • Nonphotolithographic pattern transfer for fabricating pen-shaped microneedle structures
    • Nov.
    • M. Shikida, M. Ando, Y. Ishihara, T. Ando, K. Sato, and K. Asaumi, "Nonphotolithographic pattern transfer for fabricating pen-shaped microneedle structures," J. Micromech. Microeng., vol. 14, no. 11, pp. 1462-1467, Nov. 2004.
    • (2004) J. Micromech. Microeng. , vol.14 , Issue.11 , pp. 1462-1467
    • Shikida, M.1    Ando, M.2    Ishihara, Y.3    Ando, T.4    Sato, K.5    Asaumi, K.6
  • 23
    • 0008670190 scopus 로고    scopus 로고
    • Microfabricated polysilicon microneedles for minimally invasive biomedical devices
    • Dec.
    • J. D. Zahn, N. H. Talbot, D. Liepmann, and A. P. Pisano, "Microfabricated polysilicon microneedles for minimally invasive biomedical devices," Biomed. Microdevices, vol. 2, no. 4, pp. 295-303, Dec. 2000.
    • (2000) Biomed. Microdevices , vol.2 , Issue.4 , pp. 295-303
    • Zahn, J.D.1    Talbot, N.H.2    Liepmann, D.3    Pisano, A.P.4
  • 24
    • 0032640093 scopus 로고    scopus 로고
    • Fabrication of array of hollow microcapillaries used for injection of genetic materials into animal/plant cells
    • Mar.
    • K. Chun, G. Hashiguchi, H. Toshiyoshi, and H. Fujita, "Fabrication of array of hollow microcapillaries used for injection of genetic materials into animal/plant cells," Jpn. J. Appl. Phys., vol. 38, no. 3A, pp. L279-L281, Mar. 1999.
    • (1999) Jpn. J. Appl. Phys. , vol.38 , Issue.3 A
    • Chun, K.1    Hashiguchi, G.2    Toshiyoshi, H.3    Fujita, H.4
  • 25
    • 2342632586 scopus 로고    scopus 로고
    • A tapered hollow metallic microneedle array using backside exposure of SU-8
    • Apr.
    • K. Kim, D. S. Park, H. M. Lu, W. Che, K. Kim, J. Lee, and C. H. Ahn, "A tapered hollow metallic microneedle array using backside exposure of SU-8," J. Micromech. Microeng., vol. 14, no. 4, pp. 597-603, Apr. 2004.
    • (2004) J. Micromech. Microeng. , vol.14 , Issue.4 , pp. 597-603
    • Kim, K.1    Park, D.S.2    Lu, H.M.3    Che, W.4    Kim, K.5    Lee, J.6    Ahn, C.H.7
  • 26
    • 0036007129 scopus 로고    scopus 로고
    • Macroflux® microprojection array patch technology: A new and efficient approach for intracutaneous immunization
    • DOI 10.1023/A:1013607400040
    • J. A. Matriano, M. Cormier, J. Johnson, W. A. Young, M. Buttery, K. Nyam, and P. E. Daddona, "Macroflux microprojection array patch technology: A new and efficient approach for intracutaneous immunization," Pharm. Res., vol. 19, no. 1, pp. 63-70, Jan. 2002. (Pubitemid 34075108)
    • (2002) Pharmaceutical Research , vol.19 , Issue.1 , pp. 63-70
    • Matriano, J.A.1    Cormier, M.2    Johnson, J.3    Young, W.A.4    Buttery, M.5    Nyam, K.6    Daddona, P.E.7
  • 27
    • 0038547999 scopus 로고    scopus 로고
    • Characterization of surface micromachined metallic microneedles
    • Jun.
    • S. Chandrasekaran and A. B. Frazier, "Characterization of surface micromachined metallic microneedles," J. Microelectromech. Syst., vol. 12, no. 3, pp. 289-295, Jun. 2003.
    • (2003) J. Microelectromech. Syst. , vol.12 , Issue.3 , pp. 289-295
    • Chandrasekaran, S.1    Frazier, A.B.2
  • 28
    • 0038029170 scopus 로고    scopus 로고
    • Hollow metallic micromachined needle arrays
    • Jun.
    • J. D. Brazzle, I. Papautsky, and A. B. Frazier, "Hollow metallic micromachined needle arrays," Biomed. Microdevices, vol. 2, no. 3, pp. 197-205, Jun. 2000.
    • (2000) Biomed. Microdevices , vol.2 , Issue.3 , pp. 197-205
    • Brazzle, J.D.1    Papautsky, I.2    Frazier, A.B.3
  • 30
    • 0035501453 scopus 로고    scopus 로고
    • A sampling mechanism employing the phase transition of a gel and its application to a micro analysis system imitating a mosquito
    • DOI 10.1016/S0925-4005(01)00882-6, PII S0925400501008826
    • K. Kobayashi and H. Suzuki, "A sampling mechanism employing the phase transition of a gel and its application to a micro analysis system imitating a mosquito," Sens. Actuators B, Chem., vol. 80, no. 1, pp. 1-8, Nov. 2001. (Pubitemid 32935701)
    • (2001) Sensors and Actuators, B: Chemical , vol.80 , Issue.1 , pp. 1-8
    • Kobayashi, K.1    Suzuki, H.2
  • 33
    • 21044448226 scopus 로고    scopus 로고
    • Fabrication of microneedle array using LIGA and hot embossing process
    • DOI 10.1007/s00542-004-0446-8
    • S. J. Moon, S. S. Lee, H. S. Lee, and T. H. Kwon, "Fabrication of microneedle array using LIGA and hot embossing process," Microsyst. Technol., vol. 11, no. 4/5, pp. 311-318, Apr. 2005. (Pubitemid 40871888)
    • (2005) Microsystem Technologies , vol.11 , Issue.4-5 , pp. 311-318
    • Moon, S.J.1    Lee, S.S.2    Lee, H.S.3    Kwon, T.H.4
  • 34
    • 18144410179 scopus 로고    scopus 로고
    • Biodegradable polymer microneedles: Fabrication, mechanics and transdermal drug delivery
    • DOI 10.1016/j.jconrel.2005.02.002
    • J. Park, M. G. Allen, and M. R. Prausnitz, "Biodegradable polymer microneedles: Fabrication, mechanics and transdermal drug delivery," J. Controlled Release, vol. 104, no. 1, pp. 51-66, May 2005. (Pubitemid 40615235)
    • (2005) Journal of Controlled Release , vol.104 , Issue.1 , pp. 51-66
    • Park, J.-H.1    Allen, M.G.2    Prausnitz, M.R.3
  • 35
    • 34249710930 scopus 로고    scopus 로고
    • A novel fabrication process for out-of-plane microneedle sheets of biocompatible polymer
    • DOI 10.1088/0960-1317/17/6/012, PII S0960131707366436, 012
    • M. Han, D. Hyun, H. Park, S. S. Lee, C. Kim, and C. Kim, "A novel fabrication process for out-of-plane microneedle sheets of biocompatible polymer," J. Micromech. Microeng., vol. 17, no. 6, pp. 1184-1191, Jun. 2007. (Pubitemid 46838934)
    • (2007) Journal of Micromechanics and Microengineering , vol.17 , Issue.6 , pp. 1184-1191
    • Han, M.1    Hyun, D.-H.2    Park, H.-H.3    Lee, S.S.4    Kim, C.-H.5    Kim, C.6
  • 36
    • 34248997501 scopus 로고    scopus 로고
    • Different fabrication methods of out-of-plane polymer hollow needle arrays and their variations
    • DOI 10.1088/0960-1317/17/2/027, PII S0960131707360270, 027
    • H. Huang and C. Fu, "Different fabrication methods of out-of-plane polymer hollow needle arrays and their variations," J. Micromech. Microeng., vol. 17, no. 2, pp. 393-402, Feb. 2007. (Pubitemid 46778508)
    • (2007) Journal of Micromechanics and Microengineering , vol.17 , Issue.2 , pp. 393-402
    • Huang, H.1    Fu, C.2
  • 37
    • 2942722611 scopus 로고    scopus 로고
    • A novel polymer microneedle arrays and PDMS micromolding technique
    • S. Kuo and Y. Chou, "A novel polymer microneedle arrays and PDMS micromolding technique," Tamkang J. Sci. Eng., vol. 7, no. 2, pp. 95-98, 2004.
    • (2004) Tamkang J. Sci. Eng. , vol.7 , Issue.2 , pp. 95-98
    • Kuo, S.1    Chou, Y.2
  • 38
    • 79953774155 scopus 로고    scopus 로고
    • Arrays of solvent cast hollow out-of-plane polymer microneedles for drug delivery
    • I. Mansoor, U. O. Häfeli, and B. Stoeber, "Arrays of solvent cast hollow out-of-plane polymer microneedles for drug delivery," in Proc. IEEE 24 Int. Conf. MEMS, 2011, pp. 1027-1030.
    • (2011) Proc. IEEE 24 Int. Conf. MEMS , pp. 1027-1030
    • Mansoor, I.1    Häfeli, U.O.2    Stoeber, B.3
  • 39
    • 22444445767 scopus 로고    scopus 로고
    • Solvent cast technology - A versatile tool for thin film production
    • DOI 10.1007/b107336
    • U. Siemann, "Solvent cast technology-A versatile tool for thin film production," Prog. Colloid Polym. Sci., vol. 130, pp. 1-14, 2005. (Pubitemid 41008396)
    • (2005) Progress in Colloid and Polymer Science , vol.130 , pp. 1-14
    • Siemann, U.1
  • 40
    • 0037262078 scopus 로고    scopus 로고
    • Microchannel wall coatings for protein separations by capillary and chip electrophoresis
    • E. A. S. Doherty, R. J. Meagher, M. N. Albarghouthi, and A. E. Barron, "Microchannel wall coatings for protein separations by capillary and chip electrophoresis," Electrophoresis, vol. 24, no. 1/2, pp. 34-54, Jan. 2003. (Pubitemid 36175849)
    • (2003) Electrophoresis , vol.24 , Issue.1-2 , pp. 34-54
    • Doherty, E.A.S.1    Meagher, R.J.2    Albarghouthi, M.N.3    Barron, A.E.4
  • 41
    • 44249104250 scopus 로고    scopus 로고
    • Biodegradable polylactic acid microstructures for scaffold applications
    • Jul.
    • G. J. Wang, K. H. Ho, and C. C. Hsueh, "Biodegradable polylactic acid microstructures for scaffold applications," Microsyst. Technol., vol. 14, no. 7, pp. 989-993, Jul. 2008.
    • (2008) Microsyst. Technol. , vol.14 , Issue.7 , pp. 989-993
    • Wang, G.J.1    Ho, K.H.2    Hsueh, C.C.3
  • 42
    • 4944234463 scopus 로고    scopus 로고
    • Production and characterization of polymer microcantilevers
    • Aug.
    • A. W. McFarland, M. A. Poggi, L. A. Bottomley, and J. S. Colton, "Production and characterization of polymer microcantilevers," Rev. Sci. Instrum., vol. 75, no. 8, pp. 2756-2758, Aug. 2004.
    • (2004) Rev. Sci. Instrum. , vol.75 , Issue.8 , pp. 2756-2758
    • McFarland, A.W.1    Poggi, M.A.2    Bottomley, L.A.3    Colton, J.S.4
  • 43
    • 40049112272 scopus 로고    scopus 로고
    • Dissolving microneedles for transdermal drug delivery
    • May
    • J. W. Lee, J.-H. Park, and M. R. Prausnitz, "Dissolving microneedles for transdermal drug delivery," Biomaterials, vol. 29, no. 13, pp. 2113-2124, May 2008.
    • (2008) Biomaterials , vol.29 , Issue.13 , pp. 2113-2124
    • Lee, J.W.1    Park, J.-H.2    Prausnitz, M.R.3
  • 44
    • 79959556107 scopus 로고    scopus 로고
    • PIV measurements of flow in drying polymer solutions during solvent casting
    • May
    • I. Mansoor and B. Stoeber, "PIV measurements of flow in drying polymer solutions during solvent casting," Exp. Fluids, vol. 50, no. 5, pp. 1409-1420, May 2011.
    • (2011) Exp. Fluids , vol.50 , Issue.5 , pp. 1409-1420
    • Mansoor, I.1    Stoeber, B.2
  • 45
    • 84858441010 scopus 로고    scopus 로고
    • HD Microsystems PI-2600 Series-Low Stress Applications [Online]
    • HD Microsystems, PI-2600 Series-Low Stress Applications, 2009, Product Bulletin. [Online]. Available: http://hdmicrosystems.com/HDMicroSystems/en-US/ pdf/PI-2600-ProcessGuide.pdf
    • (2009) Product Bulletin
  • 46
    • 0037677948 scopus 로고    scopus 로고
    • Building thick photoresist structures from the bottom up
    • May
    • M. C. Peterman, P. Huie, D. M. Bloom, and H. A. Fishman, "Building thick photoresist structures from the bottom up," J. Micromech. Microeng., vol. 13, no. 3, pp. 380-382, May 2003.
    • (2003) J. Micromech. Microeng. , vol.13 , Issue.3 , pp. 380-382
    • Peterman, M.C.1    Huie, P.2    Bloom, D.M.3    Fishman, H.A.4
  • 47
    • 77953479498 scopus 로고    scopus 로고
    • Measurement of the hygroscopic swelling coefficient of thin film polymers used in semiconductor packaging
    • Jun.
    • C. Jang, S. Yoon, and B. Han, "Measurement of the hygroscopic swelling coefficient of thin film polymers used in semiconductor packaging," IEEE Trans. Compon. Packag. Technol., vol. 33, no. 2, pp. 340-346, Jun. 2010.
    • (2010) IEEE Trans. Compon. Packag. Technol. , vol.33 , Issue.2 , pp. 340-346
    • Jang, C.1    Yoon, S.2    Han, B.3
  • 48
    • 84989092822 scopus 로고
    • Optical waveguiding as a method for characterizing the effect of extended cure and moisture on polyimide films
    • Aug.
    • S. C. Noe, J. Y. Pan, and S. D. Senturia, "Optical waveguiding as a method for characterizing the effect of extended cure and moisture on polyimide films," Polym. Eng. Sci., vol. 32, no. 15, pp. 1015-1020, Aug. 1992.
    • (1992) Polym. Eng. Sci. , vol.32 , Issue.15 , pp. 1015-1020
    • Noe, S.C.1    Pan, J.Y.2    Senturia, S.D.3
  • 49
    • 0035882719 scopus 로고    scopus 로고
    • Effect of montmorillonite on thermal and moisture absorption properties of polyimide of different chemical structures
    • Aug.
    • H. L. Tyan, C. Y. Wu, and K. H. Wei, "Effect of montmorillonite on thermal and moisture absorption properties of polyimide of different chemical structures," J. Appl. Polym. Sci., vol. 81, no. 7, pp. 1742-1747, Aug. 2001.
    • (2001) J. Appl. Polym. Sci. , vol.81 , Issue.7 , pp. 1742-1747
    • Tyan, H.L.1    Wu, C.Y.2    Wei, K.H.3
  • 50
    • 47249112934 scopus 로고    scopus 로고
    • Characterization of rabbit ear skin as a skin model for in vitro transdermal permeation experiments: Histology, lipid composition and permeability
    • DOI 10.1159/000135638
    • S. Nicoli, C. Padula, V. Aversa, B. Vietti, P.W.Wertz, A. Millet, F. Falson, and R. P. Feynman, "Characterization of rabbit ear skin as a skin model for in vitro transdermal permeation experiments: Histology, lipid composition and permeability," Skin Pharmacol. Physiol., vol. 21, no. 4, pp. 218-226, Jul. 2008. (Pubitemid 351989642)
    • (2008) Skin Pharmacology and Physiology , vol.21 , Issue.4 , pp. 218-226
    • Nicoli, S.1    Padula, C.2    Aversa, V.3    Vietti, B.4    Wertz, P.W.5    Millet, A.6    Falson, F.7    Govoni, P.8    Santi, P.9
  • 51
    • 0026706844 scopus 로고
    • Pig ear skin as an in-vitro model for human skin permeability
    • Aug.
    • P. Dick and R. C. Scott, "Pig ear skin as an in-vitro model for human skin permeability," J. Pharm. Pharmacol., vol. 44, no. 8, pp. 640-645, Aug. 1992.
    • (1992) J. Pharm. Pharmacol. , vol.44 , Issue.8 , pp. 640-645
    • Dick, P.1    Scott, R.C.2
  • 52
    • 0036828058 scopus 로고    scopus 로고
    • Biophysical study of porcine ear skin in vitro and its comparison to human skin in vivo
    • DOI 10.1002/jps.10220
    • N. Sekkat, Y. N. Kalia, and R. H. Guy, "Biophysical study of porcine ear skin in vitro and its comparison to human skin in vivo," J. Pharm. Sci., vol. 91, no. 11, pp. 2376-2381, Nov. 2002. (Pubitemid 35231200)
    • (2002) Journal of Pharmaceutical Sciences , vol.91 , Issue.11 , pp. 2376-2381
    • Sekkat, N.1    Kalia, Y.N.2    Guy, R.H.3
  • 53
    • 2942716734 scopus 로고    scopus 로고
    • Insertion of microneedles into skin: Measurement and prediction of insertion force and needle fracture force
    • DOI 10.1016/j.jbiomech.2003.12.010, PII S0021929003004731
    • S. P. Davis, B. J. Landis, Z. H. Adams, M. G. Allen, and M. R. Prausnitz, "Insertion of microneedles into skin: Measurement and prediction of insertion force and needle fracture force," J. Biomech., vol. 37, no. 8, pp. 1155-1163, Aug. 2004. (Pubitemid 38798369)
    • (2004) Journal of Biomechanics , vol.37 , Issue.8 , pp. 1155-1163
    • Davis, S.P.1    Landis, B.J.2    Adams, Z.H.3    Allen, M.G.4    Prausnitz, M.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.