-
1
-
-
31844443202
-
Glucagon-like peptide-1: from extract to agent. The Claude Bernard lecture, 2005
-
Holst J.J. Glucagon-like peptide-1: from extract to agent. The Claude Bernard lecture, 2005. Diabetologia 2006, 49(2):253-260.
-
(2006)
Diabetologia
, vol.49
, Issue.2
, pp. 253-260
-
-
Holst, J.J.1
-
2
-
-
75149128665
-
Incretin-based therapies for the treatment of type 2 diabetes: evaluation of the risks and benefits
-
Drucker D.J., Sherman S.I., Gorelick F.S., Bergenstal R.M., Sherwin R.S., Buse J.B. Incretin-based therapies for the treatment of type 2 diabetes: evaluation of the risks and benefits. Diabetes Care 2010, 33(2):428-433.
-
(2010)
Diabetes Care
, vol.33
, Issue.2
, pp. 428-433
-
-
Drucker, D.J.1
Sherman, S.I.2
Gorelick, F.S.3
Bergenstal, R.M.4
Sherwin, R.S.5
Buse, J.B.6
-
4
-
-
79960086290
-
The safety of incretin-based therapies: review of the scientific evidence
-
Drucker D.J., Sherman S.I., Bergenstal R.M., Buse J.B. The safety of incretin-based therapies: review of the scientific evidence. J Clin Endocrinol Metab 2011, 96(7):2027-2031.
-
(2011)
J Clin Endocrinol Metab
, vol.96
, Issue.7
, pp. 2027-2031
-
-
Drucker, D.J.1
Sherman, S.I.2
Bergenstal, R.M.3
Buse, J.B.4
-
5
-
-
0023107555
-
Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas
-
Mojsov S., Weir G.C., Habener J.F. Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas. J Clin Invest 1987, 79(2):616-619.
-
(1987)
J Clin Invest
, vol.79
, Issue.2
, pp. 616-619
-
-
Mojsov, S.1
Weir, G.C.2
Habener, J.F.3
-
6
-
-
0023104829
-
Truncated glucagon-like peptide I, an insulin-releasing hormone from the distal gut
-
Holst J.J., Orskov C., Nielsen O.V., Schwartz T.W. Truncated glucagon-like peptide I, an insulin-releasing hormone from the distal gut. FEBS Lett 1987, 211(2):169-174.
-
(1987)
FEBS Lett
, vol.211
, Issue.2
, pp. 169-174
-
-
Holst, J.J.1
Orskov, C.2
Nielsen, O.V.3
Schwartz, T.W.4
-
7
-
-
0344357096
-
Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line
-
Drucker D.J., Philippe J., Mojsov S., Chick W.L., Habener J.F. Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line. Proc Natl Acad Sci U S A 1987, 84(10):3434-3438.
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, Issue.10
, pp. 3434-3438
-
-
Drucker, D.J.1
Philippe, J.2
Mojsov, S.3
Chick, W.L.4
Habener, J.F.5
-
8
-
-
77952309372
-
Liraglutide versus sitagliptin for patients with type 2 diabetes who did not have adequate glycaemic control with metformin: a 26-week, randomised, parallel-group, open-label trial
-
Pratley R.E., Nauck M., Bailey T., Montanya E., Cuddihy R., Filetti S., et al. Liraglutide versus sitagliptin for patients with type 2 diabetes who did not have adequate glycaemic control with metformin: a 26-week, randomised, parallel-group, open-label trial. Lancet 2010, 375(9724):1447-1456.
-
(2010)
Lancet
, vol.375
, Issue.9724
, pp. 1447-1456
-
-
Pratley, R.E.1
Nauck, M.2
Bailey, T.3
Montanya, E.4
Cuddihy, R.5
Filetti, S.6
-
9
-
-
0030913210
-
Glucagon-like peptide-1 can reverse the age-related decline in glucose-tolerance in rats
-
Wang Y.H., Perfetti R., Greig N.H., Holloway H.W., Deore K.A., Montroserafizadeh C., et al. Glucagon-like peptide-1 can reverse the age-related decline in glucose-tolerance in rats. J Clin Invest 1997, 99(12):2883-2889.
-
(1997)
J Clin Invest
, vol.99
, Issue.12
, pp. 2883-2889
-
-
Wang, Y.H.1
Perfetti, R.2
Greig, N.H.3
Holloway, H.W.4
Deore, K.A.5
Montroserafizadeh, C.6
-
10
-
-
10744230106
-
GLP-1 derivative liraglutide in rats with beta-cell deficiencies: influence of metabolic state on beta-cell mass dynamics
-
Sturis J., Gotfredsen C.F., Romer J., Rolin B., Ribel U., Brand C.L., et al. GLP-1 derivative liraglutide in rats with beta-cell deficiencies: influence of metabolic state on beta-cell mass dynamics. Br J Pharmacol 2003, 140(1):123-132.
-
(2003)
Br J Pharmacol
, vol.140
, Issue.1
, pp. 123-132
-
-
Sturis, J.1
Gotfredsen, C.F.2
Romer, J.3
Rolin, B.4
Ribel, U.5
Brand, C.L.6
-
11
-
-
0033513455
-
Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats
-
Xu G., Stoffers D.A., Habener J.F., Bonner-Weir S. Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats. Diabetes 1999, 48(12):2270-2276.
-
(1999)
Diabetes
, vol.48
, Issue.12
, pp. 2270-2276
-
-
Xu, G.1
Stoffers, D.A.2
Habener, J.F.3
Bonner-Weir, S.4
-
12
-
-
0032908809
-
Initiation of increased pancreatic islet growth in young normoglycemic mice (Umeå +/?)
-
Edvell A., Lindstrom P. Initiation of increased pancreatic islet growth in young normoglycemic mice (Umeå +/?). Endocrinology 1999, 140(2):778-783.
-
(1999)
Endocrinology
, vol.140
, Issue.2
, pp. 778-783
-
-
Edvell, A.1
Lindstrom, P.2
-
13
-
-
0036828227
-
Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats
-
Farilla L., Hui H., Bertolotto C., Kang E., Bulotta A., Di M.U., Perfetti R. Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats. Endocrinology 2002, 143(11):4397-4408.
-
(2002)
Endocrinology
, vol.143
, Issue.11
, pp. 4397-4408
-
-
Farilla, L.1
Hui, H.2
Bertolotto, C.3
Kang, E.4
Bulotta, A.5
Di, M.U.6
Perfetti, R.7
-
14
-
-
0023758530
-
Effect of truncated glucagon-like peptide-1 [proglucagon-(78-107) amide] on endocrine secretion from pig pancreas, antrum, and nonantral stomach
-
Orskov C., Holst J.J., Nielsen O.V. Effect of truncated glucagon-like peptide-1 [proglucagon-(78-107) amide] on endocrine secretion from pig pancreas, antrum, and nonantral stomach. Endocrinology 1988, 123(4):2009-2013.
-
(1988)
Endocrinology
, vol.123
, Issue.4
, pp. 2009-2013
-
-
Orskov, C.1
Holst, J.J.2
Nielsen, O.V.3
-
15
-
-
77954250537
-
The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action
-
Hare K.J., Vilsboll T., Asmar M., Deacon C.F., Knop F.K., Holst J.J. The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action. Diabetes 2010, 59(7):1765-1770.
-
(2010)
Diabetes
, vol.59
, Issue.7
, pp. 1765-1770
-
-
Hare, K.J.1
Vilsboll, T.2
Asmar, M.3
Deacon, C.F.4
Knop, F.K.5
Holst, J.J.6
-
16
-
-
0032005005
-
Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans
-
Flint A., Raben A., Astrup A., Holst J.J. Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans. J Clin Invest 1998, 101(3):515-520.
-
(1998)
J Clin Invest
, vol.101
, Issue.3
, pp. 515-520
-
-
Flint, A.1
Raben, A.2
Astrup, A.3
Holst, J.J.4
-
17
-
-
34547951456
-
Liraglutide, a once-daily human glucagon-like peptide-1 analog, minimizes food intake in severely obese minipigs
-
Raun K., von Voss P., Knudsen L.B. Liraglutide, a once-daily human glucagon-like peptide-1 analog, minimizes food intake in severely obese minipigs. Obesity 2007, 15(7):1710-1716.
-
(2007)
Obesity
, vol.15
, Issue.7
, pp. 1710-1716
-
-
Raun, K.1
von Voss, P.2
Knudsen, L.B.3
-
18
-
-
35748957503
-
The physiology of glucagon-like peptide 1
-
Holst J.J. The physiology of glucagon-like peptide 1. Physiol Rev 2007, 87(4):1409-1439.
-
(2007)
Physiol Rev
, vol.87
, Issue.4
, pp. 1409-1439
-
-
Holst, J.J.1
-
19
-
-
0028803336
-
2-terminus in type II diabetic patients and in healthy subjects
-
2-terminus in type II diabetic patients and in healthy subjects. Diabetes 1995, 44(9):1126-1131.
-
(1995)
Diabetes
, vol.44
, Issue.9
, pp. 1126-1131
-
-
Deacon, C.F.1
Nauck, M.A.2
Toft-Nielsen, M.3
Pridal, L.4
Willms, B.5
Holst, J.J.6
-
20
-
-
18144401971
-
Effects of exenatide (exendin-4) on glycemic control and weight over 30weeks in metformin-treated patients with type 2 diabetes
-
DeFronzo R.A., Ratner R.E., Han J., Kim D.D., Fineman M.S., Baron A.D. Effects of exenatide (exendin-4) on glycemic control and weight over 30weeks in metformin-treated patients with type 2 diabetes. Diabetes Care 2005, 28(5):1092-1100.
-
(2005)
Diabetes Care
, vol.28
, Issue.5
, pp. 1092-1100
-
-
DeFronzo, R.A.1
Ratner, R.E.2
Han, J.3
Kim, D.D.4
Fineman, M.S.5
Baron, A.D.6
-
21
-
-
67649666737
-
Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6)
-
Buse J.B., Rosenstock J., Sesti G., Schmidt W.E., Montanya E., Brett J.H., et al. Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6). Lancet 2009, 374(9683):39-47.
-
(2009)
Lancet
, vol.374
, Issue.9683
, pp. 39-47
-
-
Buse, J.B.1
Rosenstock, J.2
Sesti, G.3
Schmidt, W.E.4
Montanya, E.5
Brett, J.H.6
-
22
-
-
0034108646
-
Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration
-
Knudsen L.B., Nielsen P.F., Huusfeldt P.O., Johansen N.L., Madsen K., Pedersen F.Z., et al. Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration. J Med Chem 2000, 43(9):1664-1669.
-
(2000)
J Med Chem
, vol.43
, Issue.9
, pp. 1664-1669
-
-
Knudsen, L.B.1
Nielsen, P.F.2
Huusfeldt, P.O.3
Johansen, N.L.4
Madsen, K.5
Pedersen, F.Z.6
-
23
-
-
0036189831
-
The pharmacokinetics, pharmacodynamics, safety and tolerability of NN2211, a new long-acting GLP-1 derivative, in healthy men
-
Agerso H., Jensen L.B., Elbrond B., Rolan P., Zdravkovic M. The pharmacokinetics, pharmacodynamics, safety and tolerability of NN2211, a new long-acting GLP-1 derivative, in healthy men. Diabetologia 2002, 45(2):195-202.
-
(2002)
Diabetologia
, vol.45
, Issue.2
, pp. 195-202
-
-
Agerso, H.1
Jensen, L.B.2
Elbrond, B.3
Rolan, P.4
Zdravkovic, M.5
-
24
-
-
66249138889
-
Glucagon-like peptide-1 and myocardial protection: more than glycemic control
-
Fields A.V., Patterson B., Karnik A.A., Shannon R.P. Glucagon-like peptide-1 and myocardial protection: more than glycemic control. Clin Cardiol 2009, 32(5):236-243.
-
(2009)
Clin Cardiol
, vol.32
, Issue.5
, pp. 236-243
-
-
Fields, A.V.1
Patterson, B.2
Karnik, A.A.3
Shannon, R.P.4
-
25
-
-
64649102619
-
GLP-1R agonist liraglutide activates cytoprotective pathways and improves outcomes after experimental myocardial infarction in mice
-
Noyan-Ashraf M.H., Abdul M.M., Ban K., Sadi A.M., Zhou Y.Q., Riazi A.M., et al. GLP-1R agonist liraglutide activates cytoprotective pathways and improves outcomes after experimental myocardial infarction in mice. Diabetes 2009, 58(4):975-983.
-
(2009)
Diabetes
, vol.58
, Issue.4
, pp. 975-983
-
-
Noyan-Ashraf, M.H.1
Abdul, M.M.2
Ban, K.3
Sadi, A.M.4
Zhou, Y.Q.5
Riazi, A.M.6
-
26
-
-
67650057935
-
A long-acting glucagon-like peptide-1 analogue attenuates induction of plasminogen activator inhibitor type-1 and vascular adhesion molecules
-
Liu H., Dear A.E., Knudsen L.B., Simpson R.W. A long-acting glucagon-like peptide-1 analogue attenuates induction of plasminogen activator inhibitor type-1 and vascular adhesion molecules. J Endocrinol 2009, 201(1):59-66.
-
(2009)
J Endocrinol
, vol.201
, Issue.1
, pp. 59-66
-
-
Liu, H.1
Dear, A.E.2
Knudsen, L.B.3
Simpson, R.W.4
-
27
-
-
0029859220
-
Central administration of GLP-1-(7-36) amide inhibits food and water intake in rats
-
Tang-Christensen M., Larsen P.J., Goke R., Fink-Jensen A., Jessop D.S., Moller M., Sheikh S.P. Central administration of GLP-1-(7-36) amide inhibits food and water intake in rats. Am J Physiol 1996, 271(4 Pt 2):R848-R856.
-
(1996)
Am J Physiol
, vol.271
, Issue.4 PART 2
-
-
Tang-Christensen, M.1
Larsen, P.J.2
Goke, R.3
Fink-Jensen, A.4
Jessop, D.S.5
Moller, M.6
Sheikh, S.P.7
-
28
-
-
2942668372
-
Glucagon-like peptide 1 induces natriuresis in healthy subjects and in insulin-resistant obese men
-
Gutzwiller J.P., Tschopp S., Bock A., Zehnder C.E., Huber A.R., Kreyenbuehl M., et al. Glucagon-like peptide 1 induces natriuresis in healthy subjects and in insulin-resistant obese men. J Clin Endocrinol Metab 2004, 89(6):3055-3061.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, Issue.6
, pp. 3055-3061
-
-
Gutzwiller, J.P.1
Tschopp, S.2
Bock, A.3
Zehnder, C.E.4
Huber, A.R.5
Kreyenbuehl, M.6
-
29
-
-
0141461415
-
Glucagon-like peptide-1 receptor is involved in learning and neuroprotection
-
During M.J., Cao L., Zuzga D.S., Francis J.S., Fitzsimons H.L., Jiao X., et al. Glucagon-like peptide-1 receptor is involved in learning and neuroprotection. Nat Med 2003, 9(9):1173-1179.
-
(2003)
Nat Med
, vol.9
, Issue.9
, pp. 1173-1179
-
-
During, M.J.1
Cao, L.2
Zuzga, D.S.3
Francis, J.S.4
Fitzsimons, H.L.5
Jiao, X.6
-
30
-
-
63249091158
-
Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntington's disease
-
Martin B., Golden E., Carlson O.D., Pistell P., Zhou J., Kim W., et al. Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntington's disease. Diabetes 2009, 58(2):318-328.
-
(2009)
Diabetes
, vol.58
, Issue.2
, pp. 318-328
-
-
Martin, B.1
Golden, E.2
Carlson, O.D.3
Pistell, P.4
Zhou, J.5
Kim, W.6
-
31
-
-
38849196303
-
Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of Parkinson's disease
-
Bertilsson G., Patrone C., Zachrisson O., Andersson A., Dannaeus K., Heidrich J., et al. Peptide hormone exendin-4 stimulates subventricular zone neurogenesis in the adult rodent brain and induces recovery in an animal model of Parkinson's disease. J Neurosci Res 2008, 86(2):326-338.
-
(2008)
J Neurosci Res
, vol.86
, Issue.2
, pp. 326-338
-
-
Bertilsson, G.1
Patrone, C.2
Zachrisson, O.3
Andersson, A.4
Dannaeus, K.5
Heidrich, J.6
-
32
-
-
67349171365
-
Molecular evolution of mammalian incretin hormone genes
-
Irwin D.M. Molecular evolution of mammalian incretin hormone genes. Regul Pept 2009, 155(1-3):121-130.
-
(2009)
Regul Pept
, vol.155
, Issue.1-3
, pp. 121-130
-
-
Irwin, D.M.1
-
33
-
-
0026775150
-
Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1
-
Thorens B. Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1. Proc Natl Acad Sci U S A 1992, 89(18):8641-8645.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, Issue.18
, pp. 8641-8645
-
-
Thorens, B.1
-
34
-
-
0027425034
-
Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor
-
Thorens B., Porret A., Buhler L., Deng S.P., Morel P., Widmann C. Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor. Diabetes 1993, 42(11):1678-1682.
-
(1993)
Diabetes
, vol.42
, Issue.11
, pp. 1678-1682
-
-
Thorens, B.1
Porret, A.2
Buhler, L.3
Deng, S.P.4
Morel, P.5
Widmann, C.6
-
35
-
-
0029958404
-
Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene
-
Scrocchi L.A., Brown T.J., MacLusky N., Brubaker P.L., Auerbach A.B., Joyner A.L., Drucker D.J. Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene. Nat Med 1996, 2(11):1254-1258.
-
(1996)
Nat Med
, vol.2
, Issue.11
, pp. 1254-1258
-
-
Scrocchi, L.A.1
Brown, T.J.2
MacLusky, N.3
Brubaker, P.L.4
Auerbach, A.B.5
Joyner, A.L.6
Drucker, D.J.7
-
36
-
-
0033304603
-
The glucagon-like peptides
-
Kieffer T.J., Habener J.F. The glucagon-like peptides. Endocr Rev 1999, 20(6):876-913.
-
(1999)
Endocr Rev
, vol.20
, Issue.6
, pp. 876-913
-
-
Kieffer, T.J.1
Habener, J.F.2
-
37
-
-
33847617011
-
Mechanisms of action of glucagon-like peptide 1 in the pancreas
-
Doyle M.E., Egan J.M. Mechanisms of action of glucagon-like peptide 1 in the pancreas. Pharmacol Ther 2007, 113(3):546-593.
-
(2007)
Pharmacol Ther
, vol.113
, Issue.3
, pp. 546-593
-
-
Doyle, M.E.1
Egan, J.M.2
-
38
-
-
43749120731
-
Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation
-
Liu Z., Habener J.F. Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation. J Biol Chem 2008, 283(13):8723-8735.
-
(2008)
J Biol Chem
, vol.283
, Issue.13
, pp. 8723-8735
-
-
Liu, Z.1
Habener, J.F.2
-
39
-
-
44349129654
-
Beta-arrestin-1 mediates glucagon-like peptide-1 signaling to insulin secretion in cultured pancreatic beta cells
-
Sonoda N., Imamura T., Yoshizaki T., Babendure J.L., Lu J.C., Olefsky J.M. Beta-arrestin-1 mediates glucagon-like peptide-1 signaling to insulin secretion in cultured pancreatic beta cells. Proc Natl Acad Sci U S A 2008, 105(18):6614-6619.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.18
, pp. 6614-6619
-
-
Sonoda, N.1
Imamura, T.2
Yoshizaki, T.3
Babendure, J.L.4
Lu, J.C.5
Olefsky, J.M.6
-
40
-
-
67849084815
-
Glucagon-like peptide-1 protects mesenteric endothelium from injury during inflammation
-
Dozier K.C., Cureton E.L., Kwan R.O., Curran B., Sadjadi J., Victorino G.P. Glucagon-like peptide-1 protects mesenteric endothelium from injury during inflammation. Peptides 2009, 30(9):1735-1741.
-
(2009)
Peptides
, vol.30
, Issue.9
, pp. 1735-1741
-
-
Dozier, K.C.1
Cureton, E.L.2
Kwan, R.O.3
Curran, B.4
Sadjadi, J.5
Victorino, G.P.6
-
41
-
-
48349144982
-
Glucagon-like peptide-1 (GLP-1) diminishes neuronal degeneration and death caused by NGF deprivation by suppressing Bim induction
-
Biswas S.C., Buteau J., Greene L.A. Glucagon-like peptide-1 (GLP-1) diminishes neuronal degeneration and death caused by NGF deprivation by suppressing Bim induction. Neurochem Res 2008, 33(9):1845-1851.
-
(2008)
Neurochem Res
, vol.33
, Issue.9
, pp. 1845-1851
-
-
Biswas, S.C.1
Buteau, J.2
Greene, L.A.3
-
42
-
-
77950228684
-
Glucagon-like peptide-1 receptor agonists activate rodent thyroid C-cells causing calcitonin release and C-cell proliferation
-
Knudsen L.B., Madsen L.W., Andersen S., Almholt K., De Boer A.S., Drucker D.J., et al. Glucagon-like peptide-1 receptor agonists activate rodent thyroid C-cells causing calcitonin release and C-cell proliferation. Endocrinology 2010, 151(4):1473-1486.
-
(2010)
Endocrinology
, vol.151
, Issue.4
, pp. 1473-1486
-
-
Knudsen, L.B.1
Madsen, L.W.2
Andersen, S.3
Almholt, K.4
De Boer, A.S.5
Drucker, D.J.6
-
43
-
-
0028198851
-
Structure-activity studies of glucagon-like peptide-1
-
Adelhorst K., Hedegaard B.B., Knudsen L.B., Kirk O. Structure-activity studies of glucagon-like peptide-1. J Biol Chem 1994, 269(9):6275-6278.
-
(1994)
J Biol Chem
, vol.269
, Issue.9
, pp. 6275-6278
-
-
Adelhorst, K.1
Hedegaard, B.B.2
Knudsen, L.B.3
Kirk, O.4
-
44
-
-
33846477446
-
Small-molecule agonists for the glucagon-like peptide 1 receptor
-
Knudsen L.B., Kiel D., Teng M., Behrens C., Bhumralkar D., Kodra J.T., et al. Small-molecule agonists for the glucagon-like peptide 1 receptor. Proc Natl Acad Sci U S A 2007, 104(3):937-942.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.3
, pp. 937-942
-
-
Knudsen, L.B.1
Kiel, D.2
Teng, M.3
Behrens, C.4
Bhumralkar, D.5
Kodra, J.T.6
-
45
-
-
0027391607
-
Preserved incretin activity of glucagon-like peptide-1 [7-36 amide] but not of synthetic human gastric-inhibitory polypeptide in patients with type-2 diabetes-mellitus
-
Nauck M.A., Heimesaat M.M., Orskov C., Holst J.J., Ebert R., Creutzfeldt W. Preserved incretin activity of glucagon-like peptide-1 [7-36 amide] but not of synthetic human gastric-inhibitory polypeptide in patients with type-2 diabetes-mellitus. J Clin Invest 1993, 91(1):301-307.
-
(1993)
J Clin Invest
, vol.91
, Issue.1
, pp. 301-307
-
-
Nauck, M.A.1
Heimesaat, M.M.2
Orskov, C.3
Holst, J.J.4
Ebert, R.5
Creutzfeldt, W.6
-
46
-
-
58149467276
-
Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes
-
Hojberg P.V., ll T., Rabol R., Knop F.K., Bache M., Krarup T., et al. Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes. Diabetologia 2009, 52(2):199-207.
-
(2009)
Diabetologia
, vol.52
, Issue.2
, pp. 199-207
-
-
Hojberg, P.V.1
ll, T.2
Rabol, R.3
Knop, F.K.4
Bache, M.5
Krarup, T.6
-
47
-
-
0037072573
-
NN2211: a long-acting glucagon-like peptide-1 derivative with anti-diabetic effects in glucose-intolerant pigs
-
Ribel U., Larsen M.O., Rolin B., Carr R.D., Wilken M., Sturis J., et al. NN2211: a long-acting glucagon-like peptide-1 derivative with anti-diabetic effects in glucose-intolerant pigs. Eur J Pharmacol 2002, 451(2):217-225.
-
(2002)
Eur J Pharmacol
, vol.451
, Issue.2
, pp. 217-225
-
-
Ribel, U.1
Larsen, M.O.2
Rolin, B.3
Carr, R.D.4
Wilken, M.5
Sturis, J.6
-
48
-
-
34548390977
-
The GLP-1 agonist exendin-4 reduces food intake in nonhuman primates through changes in meal size
-
Scott K.A., Moran T.H. The GLP-1 agonist exendin-4 reduces food intake in nonhuman primates through changes in meal size. Am J Physiol Regul Integr Comp Physiol 2007, 293(3):R983-R987.
-
(2007)
Am J Physiol Regul Integr Comp Physiol
, vol.293
, Issue.3
-
-
Scott, K.A.1
Moran, T.H.2
-
49
-
-
67149136711
-
Passing the baton in class B GPCRs: peptide hormone activation via helix induction?
-
Parthier C., Reedtz-Runge S., Rudolph R., Stubbs M.T. Passing the baton in class B GPCRs: peptide hormone activation via helix induction?. Trends Biochem Sci 2009, 34(6):303-310.
-
(2009)
Trends Biochem Sci
, vol.34
, Issue.6
, pp. 303-310
-
-
Parthier, C.1
Reedtz-Runge, S.2
Rudolph, R.3
Stubbs, M.T.4
-
50
-
-
45549086826
-
Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain
-
Runge S., Thogersen H., Madsen K., Lau J., Rudolph R. Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain. J Biol Chem 2008, 283(17):11340-11347.
-
(2008)
J Biol Chem
, vol.283
, Issue.17
, pp. 11340-11347
-
-
Runge, S.1
Thogersen, H.2
Madsen, K.3
Lau, J.4
Rudolph, R.5
-
51
-
-
0037349103
-
Different domains of the glucagon and glucagon-like peptide-1 receptors provide the critical determinants of ligand selectivity
-
Runge S., Wulff B.S., Madsen K., Brauner-Osborne H., Knudsen L.B. Different domains of the glucagon and glucagon-like peptide-1 receptors provide the critical determinants of ligand selectivity. Br J Pharmacol 2003, 138(5):787-794.
-
(2003)
Br J Pharmacol
, vol.138
, Issue.5
, pp. 787-794
-
-
Runge, S.1
Wulff, B.S.2
Madsen, K.3
Brauner-Osborne, H.4
Knudsen, L.B.5
-
52
-
-
0030921314
-
Five out of six tryptophan residues in the N-terminal extracellular domain of the rat GLP-1 receptor are essential for its ability to bind GLP-1
-
Wilmen A., Eyll B.V., Goke B., Goke R. Five out of six tryptophan residues in the N-terminal extracellular domain of the rat GLP-1 receptor are essential for its ability to bind GLP-1. Peptides 1997, 18(2):301-305.
-
(1997)
Peptides
, vol.18
, Issue.2
, pp. 301-305
-
-
Wilmen, A.1
Eyll, B.V.2
Goke, B.3
Goke, R.4
-
53
-
-
80051958802
-
Polymorphism and ligand dependent changes in human glucagon-like peptide-1 receptor (GLP-1R) function: allosteric rescue of loss of function mutation
-
Koole C., Wootten D., Simms J., Valant C., Miller L.J., Christopoulos A., et al. Polymorphism and ligand dependent changes in human glucagon-like peptide-1 receptor (GLP-1R) function: allosteric rescue of loss of function mutation. Mol Pharmacol 2011, 80(3):486-497.
-
(2011)
Mol Pharmacol
, vol.80
, Issue.3
, pp. 486-497
-
-
Koole, C.1
Wootten, D.2
Simms, J.3
Valant, C.4
Miller, L.J.5
Christopoulos, A.6
-
54
-
-
0027300816
-
The competitive and noncompetitive antagonism of receptor-mediated drug actions in the presence of spare receptors
-
Zhu B.T. The competitive and noncompetitive antagonism of receptor-mediated drug actions in the presence of spare receptors. J Pharmacol Toxicol Methods 1993, 29(2):85-91.
-
(1993)
J Pharmacol Toxicol Methods
, vol.29
, Issue.2
, pp. 85-91
-
-
Zhu, B.T.1
-
55
-
-
0032941026
-
Pancreatic glucagon-like peptide-1 receptor couples to multiple G proteins and activates mitogen-activated protein kinase pathways in Chinese hamster ovary cells
-
Montrose-Rafizadeh C., Avdonin P., Garant M.J., Rodgers B.D., Kole S., Yang H., et al. Pancreatic glucagon-like peptide-1 receptor couples to multiple G proteins and activates mitogen-activated protein kinase pathways in Chinese hamster ovary cells. Endocrinology 1999, 140(3):1132-1140.
-
(1999)
Endocrinology
, vol.140
, Issue.3
, pp. 1132-1140
-
-
Montrose-Rafizadeh, C.1
Avdonin, P.2
Garant, M.J.3
Rodgers, B.D.4
Kole, S.5
Yang, H.6
-
56
-
-
0028342447
-
Signal transduction by the cloned glucagon-like peptide-1 receptor: comparison with signaling by the endogenous receptors of beta cell lines
-
Widmann C., Burki E., Dolci W., Thorens B. Signal transduction by the cloned glucagon-like peptide-1 receptor: comparison with signaling by the endogenous receptors of beta cell lines. Mol Pharmacol 1994, 45(5):1029-1035.
-
(1994)
Mol Pharmacol
, vol.45
, Issue.5
, pp. 1029-1035
-
-
Widmann, C.1
Burki, E.2
Dolci, W.3
Thorens, B.4
-
57
-
-
0028151905
-
Rat parietal cell receptors for GLP-1-(7-36) amide: northern blot, cross-linking, and radioligand binding
-
Schmidtler J., Dehne K., Allescher H.D., Schusdziarra V., Classen M., Holst J.J., et al. Rat parietal cell receptors for GLP-1-(7-36) amide: northern blot, cross-linking, and radioligand binding. Am J Physiol 1994, 267(3 Pt 1):G423-G432.
-
(1994)
Am J Physiol
, vol.267
, Issue.3 PART 1
-
-
Schmidtler, J.1
Dehne, K.2
Allescher, H.D.3
Schusdziarra, V.4
Classen, M.5
Holst, J.J.6
-
58
-
-
33846536365
-
A nonpeptidic agonist of glucagon-like peptide 1 receptors with efficacy in diabetic db/db mice
-
Chen D., Liao J., Li N., Zhou C., Liu Q., Wang G., et al. A nonpeptidic agonist of glucagon-like peptide 1 receptors with efficacy in diabetic db/db mice. Proc Natl Acad Sci U S A 2007, 104(3):943-948.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.3
, pp. 943-948
-
-
Chen, D.1
Liao, J.2
Li, N.3
Zhou, C.4
Liu, Q.5
Wang, G.6
-
59
-
-
0030607672
-
Glucagon-like peptide-1-(9-36) amide is a major metabolite of glucagon-like peptide-1-(7-36) amide after in vivo administration to dogs, and it acts as an antagonist on the pancreatic receptor
-
Knudsen L.B., Pridal L. Glucagon-like peptide-1-(9-36) amide is a major metabolite of glucagon-like peptide-1-(7-36) amide after in vivo administration to dogs, and it acts as an antagonist on the pancreatic receptor. Eur J Pharmacol 1996, 318(2-3):429-435.
-
(1996)
Eur J Pharmacol
, vol.318
, Issue.2-3
, pp. 429-435
-
-
Knudsen, L.B.1
Pridal, L.2
-
60
-
-
43249089631
-
Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathways
-
Ban K., Noyan-Ashraf M.H., Hoefer J., Bolz S.S., Drucker D.J., Husain M. Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathways. Circulation 2008, 117(18):2340-2350.
-
(2008)
Circulation
, vol.117
, Issue.18
, pp. 2340-2350
-
-
Ban, K.1
Noyan-Ashraf, M.H.2
Hoefer, J.3
Bolz, S.S.4
Drucker, D.J.5
Husain, M.6
|