Treatment of lung cancer via telomerase inhibition: Self-assembled nanoplexes versus polymeric nanoparticles as vectors for 2′-O-Methyl-RNA

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 80, Issue 3, 2012, Pages 478-489

  Nafee, N ^a,e   Schneider, M ^a   Friebel, K ^a   Dong, M ^b   Schaefer, U F ^a   Murdter T E ^b,c   Lehr, C M ^a,d  

^a SAARLAND UNIVERSITY   (Germany)

^b DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^e Alexandria University Faculty of Pharmacy   (Egypt)

Author keywords

Aerosolization; Air interface culture; Lung cancer; Nanoparticles; Telomerase inhibitor; TRAP assay

Indexed keywords

2' O METHYL RNA; ANTISENSE OLIGONUCLEOTIDE; CHITOSAN; NANOCARRIER; NANOPARTICLE; NANOPLEX; POLYMER; TELOMERASE; TELOMERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER THERAPY; CELL MEMBRANE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME INHIBITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG CANCER; TELOMERIC REPEAT AMPLIFICATION PROTOCOL;

CELL LINE, TUMOR; CELL MEMBRANE; CHITOSAN; ENZYME INHIBITORS; GENETIC VECTORS; HUMANS; LUNG NEOPLASMS; NANOPARTICLES; NEBULIZERS AND VAPORIZERS; OLIGONUCLEOTIDES, ANTISENSE; POLYMERS; RNA; TELOMERASE; TRANSFECTION;

EID: 84858153069     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2011.11.019     Document Type: Article

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