Technetium-99m labeled pyridyl benzofuran derivatives as single photon emission computed tomography imaging probes for β-amyloid plaques in Alzheimer's brains

Journal of Medicinal Chemistry

Volumn 55, Issue 5, 2012, Pages 2279-2286

  Cheng, Yan ^a   Ono, Masahiro ^a   Kimura, Hiroyuki ^a   Ueda, Masashi ^a   Saji, Hideo ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; BENZOFURAN DERIVATIVE; MERCAPTAMINE; PYRIDINE DERIVATIVE; RHENIUM COMPLEX; TECHNETIUM 99M;

ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BODY DISTRIBUTION; BRAIN; CONTROLLED STUDY; DRUG UPTAKE; EX VIVO STUDY; MALE; MOUSE; NONHUMAN; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SYNTHESIS; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; BENZOFURANS; BRAIN; CHELATING AGENTS; COORDINATION COMPLEXES; MICE; MICE, TRANSGENIC; MOLECULAR IMAGING; PLAQUE, AMYLOID; PYRIDINES; RADIOPHARMACEUTICALS; RHENIUM; STRUCTURE-ACTIVITY RELATIONSHIP; TECHNETIUM; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 84858057477     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm201513c     Document Type: Article

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