Novel quinoxaline derivatives for in vivo imaging of β-amyloid plaques in the brain

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 14, 2011, Pages 4193-4196

  Cui, Mengchao ^a,b   Ono, Masahiro ^a   Kimura, Hiroyuki ^a   Liu, Boli ^b   Saji, Hideo ^a  

^a KYOTO UNIVERSITY   (Japan)

^b BEIJING NORMAL UNIVERSITY   (China)

Author keywords

Amyloid; Alzheimer's disease; Autoradiography; Binding assay; Imaging agent

Indexed keywords

2,3 DIHYDRO 1H IMIDAZO[1,2 B]PYRAZOLE I 125; AMYLOID BETA PROTEIN[1-42]; CONTRAST MEDIUM; IODINE 125; QUINOXALINE DERIVATIVE; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; IN VIVO STUDY; MOUSE; NEUROIMAGING; NONHUMAN;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; AUTORADIOGRAPHY; BRAIN; DISEASE MODELS, ANIMAL; HUMANS; IODINE RADIOISOTOPES; MICE; MICE, TRANSGENIC; PEPTIDE FRAGMENTS; PLAQUE, AMYLOID; PROTEIN BINDING; QUINOXALINES; RADIOPHARMACEUTICALS; TISSUE DISTRIBUTION;

ANIMALIA; MUS;

EID: 79959905352     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.05.079     Document Type: Article

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