-
1
-
-
0017726281
-
Legionnaires' disease: Description of an epidemic of pneumonia
-
Fraser DW, Tsai TR, Orenstein W et al. Legionnaires' disease: description of an epidemic of pneumonia. N. Engl. J. Med. 297(22), 1189-1197 (1977).
-
(1977)
N. Engl. J. Med.
, vol.297
, Issue.22
, pp. 1189-1197
-
-
Fraser, D.W.1
Tsai, T.R.2
Orenstein, W.3
-
2
-
-
0018885613
-
Legionnaires' disease bacterium (Legionella pneumophila) multiples intracellularly in human monocytes
-
Horwitz MA, Silverstein SC. Legionnaires' disease bacterium (Legionella pneumophila) multiples intracellularly in human monocytes. J. Clin. Invest. 66(3), 441-450 (1980).
-
(1980)
J. Clin. Invest.
, vol.66
, Issue.3
, pp. 441-450
-
-
Horwitz, M.A.1
Silverstein, S.C.2
-
3
-
-
0021169749
-
Interaction between the Legionnaires' disease bacterium (Legionella pneumophila) and human alveolar macrophages. Influence of antibody, lymphokines, and hydrocortisone
-
Nash TW, Libby DM, Horwitz MA. Interaction between the Legionnaires' disease bacterium (Legionella pneumophila) and human alveolar macrophages. Influence of antibody, lymphokines, and hydrocortisone. J. Clin. Invest. 74(3), 771-782 (1984).
-
(1984)
J. Clin. Invest.
, vol.74
, Issue.3
, pp. 771-782
-
-
Nash, T.W.1
Libby, D.M.2
Horwitz, M.A.3
-
4
-
-
0019254065
-
Preliminary report on the pathogenicity of Legionella pneumophila for freshwater and soil amoebae
-
Rowbotham TJ. Preliminary report on the pathogenicity of Legionella pneumophila for freshwater and soil amoebae. J. Clin. Pathol. 33(12), 1179-1183 (1980).
-
(1980)
J. Clin. Pathol.
, vol.33
, Issue.12
, pp. 1179-1183
-
-
Rowbotham, T.J.1
-
5
-
-
0032539674
-
Host cell killing and bacterial conjugation require overlapping sets of genes within a 22-kb region of the Legionella pneumophila genome
-
Segal G, Purcell M, Shuman HA. Host cell killing and bacterial conjugation require overlapping sets of genes within a 22-kb region of the Legionella pneumophila genome. Proc. Natl Acad. Sci. USA 95(4), 1669-1674 (1998).
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, Issue.4
, pp. 1669-1674
-
-
Segal, G.1
Purcell, M.2
Shuman, H.A.3
-
6
-
-
0032932436
-
Legionella pneumophila utilizes the same genes to multiply within Acanthamoeba castellanii and human macrophages
-
Segal G, Shuman HA. Legionella pneumophila utilizes the same genes to multiply within Acanthamoeba castellanii and human macrophages. Infect. Immun. 67(5), 2117-2124 (1999).
-
(1999)
Infect. Immun.
, vol.67
, Issue.5
, pp. 2117-2124
-
-
Segal, G.1
Shuman, H.A.2
-
7
-
-
0032488861
-
Conjugative transfer by the virulence system of Legionella pneumophila
-
Vogel JP, Andrews HL, Wong SK, Isberg RR. Conjugative transfer by the virulence system of Legionella pneumophila. Science 279(5352), 873-876 (1998).
-
(1998)
Science
, vol.279
, Issue.5352
, pp. 873-876
-
-
Vogel, J.P.1
Andrews, H.L.2
Wong, S.K.3
Isberg, R.R.4
-
8
-
-
0027472133
-
Two distinct defects in intracellular growth complemented by a single genetic locus in Legionella pneumophila
-
Berger KH, Isberg RR. Two distinct defects in intracellular growth complemented by a single genetic locus in Legionella pneumophila. Mol. Microbiol. 7(1), 7-19 (1993).
-
(1993)
Mol. Microbiol.
, vol.7
, Issue.1
, pp. 7-19
-
-
Berger, K.H.1
Isberg, R.R.2
-
9
-
-
0026738809
-
Identification of a Legionella pneumophila locus required for intracellular multiplication in human macrophages
-
Marra A, Blander SJ, Horwitz MA, Shuman HA. Identification of a Legionella pneumophila locus required for intracellular multiplication in human macrophages. Proc. Natl Acad. Sci. USA 89(20), 9607-9611 (1992).
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, Issue.20
, pp. 9607-9611
-
-
Marra, A.1
Blander, S.J.2
Horwitz, M.A.3
Shuman, H.A.4
-
10
-
-
70049110355
-
Genome-scale identification of Legionella pneumophila effectors using a machine learning approach
-
Employed a new bioinformatics approach based on machine learning to identify secreted subtstrates of the Dot/Icm type IV secretion system
-
Burstein D, Zusman T, Degtyar E, Viner R, Segal G, Pupko T. Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7), E1000508 (2009). Employed a new bioinformatics approach based on machine learning to identify secreted subtstrates of the Dot/Icm type IV secretion system.
-
(2009)
PLoS Pathog.
, vol.5
, Issue.7
-
-
Burstein, D.1
Zusman, T.2
Degtyar, E.3
Viner, R.4
Segal, G.5
Pupko, T.6
-
11
-
-
18444408390
-
A yeast genetic system for the identification and characterization of substrate proteins transferred into host cells by the Legionella pneumophila Dot/Icm system
-
Reported a random screening assay to identify bacterial proteins that conferred a conditional growth defect in yeast
-
Campodonico EM, Chesnel L, Roy CR. A yeast genetic system for the identification and characterization of substrate proteins transferred into host cells by the Legionella pneumophila Dot/Icm system. Mol. Microbiol. 56(4), 918-933 (2005). Reported a random screening assay to identify bacterial proteins that conferred a conditional growth defect in yeast.
-
(2005)
Mol. Microbiol.
, vol.56
, Issue.4
, pp. 918-933
-
-
Campodonico, E.M.1
Chesnel, L.2
Roy, C.R.3
-
12
-
-
50849115482
-
Legionella eukaryotic-like type IV substrates interfere with organelle trafficking
-
De Felipe KS, Glover RT, Charpentier X et al. Legionella eukaryotic-like type IV substrates interfere with organelle trafficking. PLoS Pathog. 4(8), E1000117 (2008).
-
(2008)
PLoS Pathog.
, vol.4
, Issue.8
-
-
De Felipe, K.S.1
Glover, R.T.2
Charpentier, X.3
-
13
-
-
27744546297
-
Evidence for acquisition of Legionella type IV secretion substrates via interdomain horizontal gene transfer
-
Used for the first time a fluorescence-based translocation assay to identify Dot/Icm secreted substrates
-
De Felipe KS, Pampou S, Jovanovic OS et al. Evidence for acquisition of Legionella type IV secretion substrates via interdomain horizontal gene transfer. J. Bacteriol. 187(22), 7716-7726 (2005). Used for the first time a fluorescence-based translocation assay to identify Dot/Icm secreted substrates.
-
(2005)
J. Bacteriol.
, vol.187
, Issue.22
, pp. 7716-7726
-
-
De Felipe, K.S.1
Pampou, S.2
Jovanovic, O.S.3
-
14
-
-
58349107899
-
Large-scale identification of Legionella pneumophila Dot/Icm substrates that modulate host cell vesicle trafficking pathways
-
Heidtman M, Chen EJ, Moy MY, Isberg RR. Large-scale identification of Legionella pneumophila Dot/Icm substrates that modulate host cell vesicle trafficking pathways. Cell. Microbiol. 11(2), 230-248 (2009).
-
(2009)
Cell. Microbiol.
, vol.11
, Issue.2
, pp. 230-248
-
-
Heidtman, M.1
Chen, E.J.2
Moy, M.Y.3
Isberg, R.R.4
-
15
-
-
16344374697
-
Pathogen effector protein screening in yeast identifies Legionella factors that interfere with membrane trafficking
-
Utilized for the first time effector protein screening in yeast to identify bacterial proteins that produced membrane trafficking defects in yeast
-
Shohdy N, Efe JA, Emr SD, Shuman HA. Pathogen effector protein screening in yeast identifies Legionella factors that interfere with membrane trafficking. Proc. Natl Acad. Sci. USA 102(13), 4866-4871 (2005). Utilized for the first time effector protein screening in yeast to identify bacterial proteins that produced membrane trafficking defects in yeast.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, Issue.13
, pp. 4866-4871
-
-
Shohdy, N.1
Efe, J.A.2
Emr, S.D.3
Shuman, H.A.4
-
16
-
-
79952403625
-
Comprehensive identification of protein substrates of the Dot/Icm type IV transporter of Legionella pneumophila
-
Zhu W, Banga S, Tan Y et al. Comprehensive identification of protein substrates of the Dot/Icm type IV transporter of Legionella pneumophila. PLoS One 6(3), E17638 (2011).
-
(2011)
PLoS One
, vol.6
, Issue.3
-
-
Zhu, W.1
Banga, S.2
Tan, Y.3
-
17
-
-
10044263696
-
Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity
-
Cazalet C, Rusniok C, Bruggemann H et al. Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity. Nat. Genet. 36(11), 1165-1173 (2004).
-
(2004)
Nat. Genet.
, vol.36
, Issue.11
, pp. 1165-1173
-
-
Cazalet, C.1
Rusniok, C.2
Bruggemann, H.3
-
18
-
-
4644276577
-
The genomic sequence of the accidental pathogen Legionella pneumophila
-
Chien M, Morozova I, Shi S et al. The genomic sequence of the accidental pathogen Legionella pneumophila. Science 305(5692), 1966-1968 (2004).
-
(2004)
Science
, vol.305
, Issue.5692
, pp. 1966-1968
-
-
Chien, M.1
Morozova, I.2
Shi, S.3
-
19
-
-
67649388172
-
From pathogenesis to cell biology and back
-
Mostowy S, Cossart P. From pathogenesis to cell biology and back. Cell Host Microbe 5(6), 510-513 (2009).
-
(2009)
Cell Host Microbe
, vol.5
, Issue.6
, pp. 510-513
-
-
Mostowy, S.1
Cossart, P.2
-
20
-
-
78049370513
-
Modulation of host cell function by Legionella pneumophila type IV effectors
-
Hubber A, Roy CR. Modulation of host cell function by Legionella pneumophila type IV effectors. Annu. Rev. Cell. Dev. Biol. 26, 261-283 (2010).
-
(2010)
Annu. Rev. Cell. Dev. Biol.
, vol.26
, pp. 261-283
-
-
Hubber, A.1
Roy, C.R.2
-
21
-
-
57649149094
-
The Legionella pneumophila replication vacuole: Making a cosy niche inside host cells
-
Isberg RR, O'Connor TJ, Heidtman M. The Legionella pneumophila replication vacuole: making a cosy niche inside host cells. Nat. Rev. Microbiol. 7(1), 13-24 (2009).
-
(2009)
Nat. Rev. Microbiol.
, vol.7
, Issue.1
, pp. 13-24
-
-
Isberg, R.R.1
O'Connor, T.J.2
Heidtman, M.3
-
22
-
-
69849087003
-
Molecular mimicry: An important virulence strategy employed by Legionella pneumophila to subvert host functions
-
Nora T, Lomma M, Gomez-Valero L, Buchrieser C. Molecular mimicry: an important virulence strategy employed by Legionella pneumophila to subvert host functions. Future Microbiol. 4, 691-701 (2009).
-
(2009)
Future Microbiol.
, vol.4
, pp. 691-701
-
-
Nora, T.1
Lomma, M.2
Gomez-Valero, L.3
Buchrieser, C.4
-
23
-
-
33745800293
-
Interpreting the protein language using proteomics
-
Jensen ON. Interpreting the protein language using proteomics. Nat. Rev. Mol. Cell. Biol. 7(6), 391-403 (2006).
-
(2006)
Nat. Rev. Mol. Cell. Biol.
, vol.7
, Issue.6
, pp. 391-403
-
-
Jensen, O.N.1
-
24
-
-
78650153662
-
Pathogen-mediated posttranslational modifications: A re-emerging field
-
Up-to-date review on how different bacterial pathogens may modulate host functions through post-translational modifications
-
Ribet D, Cossart P. Pathogen-mediated posttranslational modifications: a re-emerging field. Cell 143(5), 694-702 (2011). Up-to-date review on how different bacterial pathogens may modulate host functions through post-translational modifications.
-
(2011)
Cell
, vol.143
, Issue.5
, pp. 694-702
-
-
Ribet, D.1
Cossart, P.2
-
25
-
-
65649115267
-
Recognition and processing of ubiquitin-protein conjugates by the proteasome
-
Finley D. Recognition and processing of ubiquitin-protein conjugates by the proteasome. Annu. Rev. Biochem. 78, 477-513 (2009).
-
(2009)
Annu. Rev. Biochem.
, vol.78
, pp. 477-513
-
-
Finley, D.1
-
26
-
-
1542344435
-
Proteasomes and their kin: Proteases in the machine age
-
Pickart CM, Cohen RE. Proteasomes and their kin: proteases in the machine age. Nat. Rev. Mol. Cell. Biol. 5(3), 177-187 (2004).
-
(2004)
Nat. Rev. Mol. Cell. Biol.
, vol.5
, Issue.3
, pp. 177-187
-
-
Pickart, C.M.1
Cohen, R.E.2
-
27
-
-
78650100616
-
Ubiquitin: Same molecule, different degradation pathways
-
Clague MJ, Urbé S. Ubiquitin: same molecule, different degradation pathways. Cell 143(5), 682-685 (2010).
-
(2010)
Cell
, vol.143
, Issue.5
, pp. 682-685
-
-
Clague, M.J.1
Urbé, S.2
-
28
-
-
8844237615
-
Polyubiquitin chains: Polymeric protein signals
-
Pickart CM, Fushman D. Polyubiquitin chains: polymeric protein signals. Curr. Opin. Chem. Biol. 8(6), 610-616 (2004).
-
(2004)
Curr. Opin. Chem. Biol.
, vol.8
, Issue.6
, pp. 610-616
-
-
Pickart, C.M.1
Fushman, D.2
-
29
-
-
0035292759
-
Themes and variations on ubiquitylation
-
Weissman AM. Themes and variations on ubiquitylation. Nat. Rev. Mol. Cell. Biol. 2(3), 169-178 (2001).
-
(2001)
Nat. Rev. Mol. Cell. Biol.
, vol.2
, Issue.3
, pp. 169-178
-
-
Weissman, A.M.1
-
30
-
-
47549111312
-
Structural insights into E1-catalyzed ubiquitin activation and transfer to conjugating enzymes
-
Lee I, Schindelin H. Structural insights into E1-catalyzed ubiquitin activation and transfer to conjugating enzymes. Cell 134(2), 268-278 (2008).
-
(2008)
Cell
, vol.134
, Issue.2
, pp. 268-278
-
-
Lee, I.1
Schindelin, H.2
-
31
-
-
77951651753
-
The family of ubiquitin-conjugating enzymes (E2s): Deciding between life and death of proteins
-
Van Wijk SJ, Timmers HT. The family of ubiquitin-conjugating enzymes (E2s): deciding between life and death of proteins. FASEB J. 24(4), 981-993 (2010).
-
(2010)
FASEB J.
, vol.24
, Issue.4
, pp. 981-993
-
-
Van Wijk, S.J.1
Timmers, H.T.2
-
33
-
-
77649328287
-
Animal HECT ubiquitin ligases: Evolution and functional implications
-
Marín I. Animal HECT ubiquitin ligases: evolution and functional implications. BMC Evol. Biol. 10, 56 (2010).
-
(2010)
BMC Evol. Biol.
, vol.10
, pp. 56
-
-
Marín, I.1
-
34
-
-
67349132223
-
Physiological functions of the HECT family of ubiquitin ligases
-
Rotin D, Kumar S. Physiological functions of the HECT family of ubiquitin ligases. Nat. Rev. Mol. Cell. Biol. 10(6), 398-409 (2009).
-
(2009)
Nat. Rev. Mol. Cell. Biol.
, vol.10
, Issue.6
, pp. 398-409
-
-
Rotin, D.1
Kumar, S.2
-
36
-
-
0035980094
-
U box proteins as a new family of ubiquitin-protein ligases
-
Hatakeyama S, Yada M, Matsumoto M, Ishida N, Nakayama KI. U box proteins as a new family of ubiquitin-protein ligases. J. Biol. Chem. 276(35), 33111-33120 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.35
, pp. 33111-33120
-
-
Hatakeyama, S.1
Yada, M.2
Matsumoto, M.3
Ishida, N.4
Nakayama, K.I.5
-
37
-
-
68049084674
-
Breaking the chains: Structure and function of the deubiquitinases
-
Komander D, Clague MJ, Urbe S. Breaking the chains: structure and function of the deubiquitinases. Nat. Rev. Mol. Cell. Biol. 10, 550-563 (2009).
-
(2009)
Nat. Rev. Mol. Cell. Biol.
, vol.10
, pp. 550-563
-
-
Komander, D.1
Clague, M.J.2
Urbe, S.3
-
38
-
-
33947714944
-
Bacterial interference of ubiquitination and deubiquitination
-
Rytkonen A, Holden DW. Bacterial interference of ubiquitination and deubiquitination. Cell Host Microbe 1(1), 13-22 (2007).
-
(2007)
Cell Host Microbe
, vol.1
, Issue.1
, pp. 13-22
-
-
Rytkonen, A.1
Holden, D.W.2
-
39
-
-
33750034105
-
The inflammation-associated Salmonella SopA is a HECT-like E3 ubiquitin ligase
-
Zhang Y, Higashide WM, McCormick BA, Chen J, Zhou D. The inflammation-associated Salmonella SopA is a HECT-like E3 ubiquitin ligase. Mol. Microbiol. 62(3), 786-793 (2006).
-
(2006)
Mol. Microbiol.
, vol.62
, Issue.3
, pp. 786-793
-
-
Zhang, Y.1
Higashide, W.M.2
McCormick, B.A.3
Chen, J.4
Zhou, D.5
-
40
-
-
33947727977
-
Type III secretion effectors of the IpaH family are E3 ubiquitin ligases
-
Rohde JR, Breitkreutz A, Chenal A, Sansonetti PJ, Parsot C. Type III secretion effectors of the IpaH family are E3 ubiquitin ligases. Cell Host Microbe 1(1), 77-83 (2007).
-
(2007)
Cell Host Microbe
, vol.1
, Issue.1
, pp. 77-83
-
-
Rohde, J.R.1
Breitkreutz, A.2
Chenal, A.3
Sansonetti, P.J.4
Parsot, C.5
-
41
-
-
44449107633
-
Salmonella secreted factor L deubiquitinase of Salmonella typhimurium inhibits NF-kappaB, suppresses IkappaBalpha ubiquitination and modulates innate immune responses
-
Le Negrate G, Faustin B, Welsh K et al. Salmonella secreted factor L deubiquitinase of Salmonella typhimurium inhibits NF-kappaB, suppresses IkappaBalpha ubiquitination and modulates innate immune responses. J. Immunol. 80(7), 5045-5056 (2008).
-
(2008)
J. Immunol.
, vol.80
, Issue.7
, pp. 5045-5056
-
-
Le Negrate, G.1
Faustin, B.2
Welsh, K.3
-
42
-
-
39849096721
-
Legionella translocates an E3 ubiquitin ligase that has multiple U-boxes with distinct functions
-
Kubori T, Hyakutake A, Nagai H. Legionella translocates an E3 ubiquitin ligase that has multiple U-boxes with distinct functions. Mol. Microbiol. 67(6), 1307-1319 (2008).
-
(2008)
Mol. Microbiol.
, vol.67
, Issue.6
, pp. 1307-1319
-
-
Kubori, T.1
Hyakutake, A.2
Nagai, H.3
-
43
-
-
78651234971
-
Legionella metaeffector exploits host proteasome to temporally regulate cognate effector
-
Demonstrates for the first time that a bacterial effector can regulate the activity of another bacterial effector in the host cell
-
Kubori T, Shinzawa N, Kanuka H, Nagai H. Legionella metaeffector exploits host proteasome to temporally regulate cognate effector. PLoS Pathog. 6(12), E1001216 (2010). Demonstrates for the first time that a bacterial effector can regulate the activity of another bacterial effector in the host cell.
-
(2010)
PLoS Pathog.
, vol.6
, Issue.12
-
-
Kubori, T.1
Shinzawa, N.2
Kanuka, H.3
Nagai, H.4
-
44
-
-
0033613222
-
RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination
-
Lorick KL, Jensen JP, Fang S, Ong AM, Hatakeyama S, Weissman AM. RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination. Proc. Natl Acad. Sci. USA 96(20), 11364-11369 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, Issue.20
, pp. 11364-11369
-
-
Lorick, K.L.1
Jensen, J.P.2
Fang, S.3
Ong, A.M.4
Hatakeyama, S.5
Weissman, A.M.6
-
45
-
-
0030695025
-
A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p
-
Feldman RM, Correll CC, Kaplan KB, Deshaies RJ. A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p. Cell 91(2), 221-230 (1997).
-
(1997)
Cell
, vol.91
, Issue.2
, pp. 221-230
-
-
Feldman, R.M.1
Correll, C.C.2
Kaplan, K.B.3
Deshaies, R.J.4
-
46
-
-
0030662523
-
F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex
-
Skowyra D, Craig KL, Tyers M, Elledge SJ, Harper JW. F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex. Cell 91(2), 209-219 (1997).
-
(1997)
Cell
, vol.91
, Issue.2
, pp. 209-219
-
-
Skowyra, D.1
Craig, K.L.2
Tyers, M.3
Elledge, S.J.4
Harper, J.W.5
-
47
-
-
67549093540
-
SnapShot: F box proteins II
-
Skaar JR, D'Angiolella V, Pagan JK, Pagano M. SnapShot: F box proteins II. Cell 137(7), 1358.E1 (2009).
-
(2009)
Cell
, vol.137
, Issue.7
-
-
Skaar, J.R.1
D'Angiolella, V.2
Pagan, J.K.3
Pagano, M.4
-
48
-
-
67549093540
-
SnapShot: F box proteins I
-
Skaar JR, Pagan JK, Pagano M. SnapShot: F box proteins I. Cell 137(6), 1160.E1 (2009).
-
(2009)
Cell
, vol.137
, Issue.6
-
-
Skaar, J.R.1
Pagan, J.K.2
Pagano, M.3
-
49
-
-
33846574355
-
Exploitation of eukaryotic ubiquitin signaling pathways by effectors translocated by bacterial type III and type IV secretion systems
-
Comprehensive review on how different bacterial pathogens exploit the host ubiquitin pathways
-
Angot A, Vergunst A, Genin S, Peeters N. Exploitation of eukaryotic ubiquitin signaling pathways by effectors translocated by bacterial type III and type IV secretion systems. PLoS Pathog. 3(1), E3 (2007). Comprehensive review on how different bacterial pathogens exploit the host ubiquitin pathways.
-
(2007)
PLoS Pathog.
, vol.3
, Issue.1
-
-
Angot, A.1
Vergunst, A.2
Genin, S.3
Peeters, N.4
-
50
-
-
33646234683
-
RNA interference analysis of Legionella in Drosophila cells: Exploitation of early secretory apparatus dynamics
-
Dorer MS, Kirton D, Bader JS, Isberg RR. RNA interference analysis of Legionella in Drosophila cells: exploitation of early secretory apparatus dynamics. PLoS Pathog. 2(4), E34 (2006).
-
(2006)
PLoS Pathog.
, vol.2
, Issue.4
-
-
Dorer, M.S.1
Kirton, D.2
Bader, J.S.3
Isberg, R.R.4
-
51
-
-
54249166663
-
Dot/Icm-translocated ankyrin protein of Legionella pneumophila is required for intracellular proliferation within human macrophages and protozoa
-
Al-Khodor S, Price CT, Habyarimana F, Kalia A, Abu Kwaik Y. A Dot/Icm-translocated ankyrin protein of Legionella pneumophila is required for intracellular proliferation within human macrophages and protozoa. Mol. Microbiol. 70(4), 908-923 (2008).
-
(2008)
Mol. Microbiol.
, vol.70
, Issue.4
, pp. 908-923
-
-
Al-Khodor, S.1
Price, C.T.2
Habyarimana, F.3
Kalia, A.4
Abu Kwaik, Y.A.5
-
52
-
-
77953704524
-
The Legionella pneumophila F-box protein Lpp2082 (AnkB) modulates ubiquitination of the host protein parvin B and promotes intracellular replication
-
Lomma M, Dervins-Ravault D, Rolando M et al. The Legionella pneumophila F-box protein Lpp2082 (AnkB) modulates ubiquitination of the host protein parvin B and promotes intracellular replication. Cell. Microbiol. 12(9), 1272-1291 (2010).
-
(2010)
Cell. Microbiol.
, vol.12
, Issue.9
, pp. 1272-1291
-
-
Lomma, M.1
Dervins-Ravault, D.2
Rolando, M.3
-
53
-
-
74549200971
-
Molecular mimicry by an F-box effector of Legionella pneumophila hijacks a conserved polyubiquitination machinery within macrophages and protozoa
-
Price CT, Al-Khodor S, Al-Quadan T et al. Molecular mimicry by an F-box effector of Legionella pneumophila hijacks a conserved polyubiquitination machinery within macrophages and protozoa. PLoS Pathog. 5(12), E1000704 (2009).
-
(2009)
PLoS Pathog.
, vol.5
, Issue.12
-
-
Price, C.T.1
Al-Khodor, S.2
Al-Quadan, T.3
-
54
-
-
0035126590
-
Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily
-
Olski TM, Noegel AA, Korenbaum E. Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily. J. Cell Sci. 114(Pt 3), 525-538 (2001).
-
(2001)
J. Cell Sci.
, vol.114
, Issue.PART 3
, pp. 525-538
-
-
Olski, T.M.1
Noegel, A.A.2
Korenbaum, E.3
-
55
-
-
0035844879
-
A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction
-
Yamaji S, Suzuki A, Sugiyama Y et al. A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction. J. Cell Biol. 153(6), 1251-1264 (2001).
-
(2001)
J. Cell Biol.
, vol.153
, Issue.6
, pp. 1251-1264
-
-
Yamaji, S.1
Suzuki, A.2
Sugiyama, Y.3
-
57
-
-
77956644100
-
E3 ubiquitin ligase activity and targeting of BAT3 by multiple Legionella pneumophila translocated substrates
-
Ensminger AW, Isberg RR. E3 ubiquitin ligase activity and targeting of BAT3 by multiple Legionella pneumophila translocated substrates. Infect. Immun. 78(9), 3905-3919 (2010).
-
(2010)
Infect. Immun.
, vol.78
, Issue.9
, pp. 3905-3919
-
-
Ensminger, A.W.1
Isberg, R.R.2
-
58
-
-
58349085112
-
Modulation of ubiquitin dynamics and suppression of DALIS formation by the Legionella pneumophila Dot/Icm system
-
Ivanov SS, Roy CR. Modulation of ubiquitin dynamics and suppression of DALIS formation by the Legionella pneumophila Dot/Icm system. Cell. Microbiol. 11(2), 261-278 (2009).
-
(2009)
Cell. Microbiol.
, vol.11
, Issue.2
, pp. 261-278
-
-
Ivanov, S.S.1
Roy, C.R.2
-
59
-
-
14044263586
-
Cutting edge: Microbial products elicit formation of dendritic cell aggresome-like induced structures in macrophages
-
Canadien V, Tan T, Zilber R, Szeto J, Perrin AJ, Brumell JH. Cutting edge: microbial products elicit formation of dendritic cell aggresome-like induced structures in macrophages. J. Immunol. 174(5), 2471-2475 (2005).
-
(2005)
J. Immunol.
, vol.174
, Issue.5
, pp. 2471-2475
-
-
Canadien, V.1
Tan, T.2
Zilber, R.3
Szeto, J.4
Perrin, A.J.5
Brumell, J.H.6
-
60
-
-
78049354410
-
Lipidation by the host prenyltransferase machinery facilitates membrane localization of Legionella pneumophila effector proteins
-
First description showing that a bacterial effector can exploit the host prenylation (farnesylation) machinery
-
Ivanov SS, Charron G, Hang HC, Roy CR. Lipidation by the host prenyltransferase machinery facilitates membrane localization of Legionella pneumophila effector proteins. J. Biol. Chem. 285(45), 34686-34698 (2010). First description showing that a bacterial effector can exploit the host prenylation (farnesylation) machinery.
-
(2010)
J. Biol. Chem.
, vol.285
, Issue.45
, pp. 34686-34698
-
-
Ivanov, S.S.1
Charron, G.2
Hang, H.C.3
Roy, C.R.4
-
61
-
-
77955397296
-
Exploitation of conserved eukaryotic host cell farnesylation machinery by an F-box effector of Legionella pneumophila
-
First description showing that a bacterial effector can exploit the host prenylation (farnesylation) machinery
-
Price CT, Al-Quadan T, Santic M, Jones SC, Abu Kwaik Y. Exploitation of conserved eukaryotic host cell farnesylation machinery by an F-box effector of Legionella pneumophila. J. Exp. Med. 207(8), 1713-1726 (2010). First description showing that a bacterial effector can exploit the host prenylation (farnesylation) machinery.
-
(2010)
J. Exp. Med.
, vol.207
, Issue.8
, pp. 1713-1726
-
-
Price, C.T.1
Al-Quadan, T.2
Santic, M.3
Jones, S.C.4
Abu Kwaik, Y.5
-
62
-
-
33646777423
-
Thematic review series: Lipid posttranslational modifications. CAAX modification and membrane targeting of Ras
-
Wright LP, Philips MR. Thematic review series: lipid posttranslational modifications. CAAX modification and membrane targeting of Ras. J. Lipid Res. 47(5), 883-891 (2006).
-
(2006)
J. Lipid Res.
, vol.47
, Issue.5
, pp. 883-891
-
-
Wright, L.P.1
Philips, M.R.2
-
63
-
-
82355191738
-
Anchoring of bacterial effectors to host membranes through host-mediated lipidation by prenylation: A common paradigm
-
Al-Quadan T, Price CT, London N, Schueler-Furman O, Abu Kwaik Y. Anchoring of bacterial effectors to host membranes through host-mediated lipidation by prenylation: a common paradigm. Trends Microbiol. 19(12), 573-579 (2011).
-
(2011)
Trends Microbiol.
, vol.19
, Issue.12
, pp. 573-579
-
-
Al-Quadan, T.1
Price, C.T.2
London, N.3
Schueler-Furman, O.4
Abu Kwaik, Y.5
-
64
-
-
80055093214
-
Host-mediated post-translational prenylation of novel Dot/Icm-translocated effectors of Legionella pneumophila
-
Price CT, Jones SC, Amundson KE, Kwaik YA. Host-mediated post-translational prenylation of novel Dot/Icm-translocated effectors of Legionella pneumophila. Front. Microbiol. 1, 131 (2010).
-
(2010)
Front. Microbiol.
, vol.1
, pp. 131
-
-
Price, C.T.1
Jones, S.C.2
Amundson, K.E.3
Kwaik, Y.A.4
-
65
-
-
80855133900
-
Exploitation of host polyubiquitination machinery through molecular mimicry by eukaryotic-like bacterial F-Box effectors
-
Price CT, Kwaik YA. Exploitation of host polyubiquitination machinery through molecular mimicry by eukaryotic-like bacterial F-Box effectors. Front. Microbiol. 1, 122 (2010).
-
(2010)
Front. Microbiol.
, vol.1
, pp. 122
-
-
Price, C.T.1
Kwaik, Y.A.2
-
66
-
-
83855160757
-
Host proteasomal degradation generates amino acids essential for intracellular bacterial growth
-
Price CT, Al-Quadan T, Santic M, Rosenshine I, Abu Kwaik Y. Host proteasomal degradation generates amino acids essential for intracellular bacterial growth. Science 334(6062), 1553-1557 (2011).
-
(2011)
Science
, vol.334
, Issue.6062
, pp. 1553-1557
-
-
Price, C.T.1
Al-Quadan, T.2
Santic, M.3
Rosenshine, I.4
Abu Kwaik, Y.5
-
67
-
-
0028838971
-
Protein kinases and phosphatases: The yin and yang of protein phosphorylation and signaling
-
Hunter T. Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling. Cell 80(2), 225-236 (1995).
-
(1995)
Cell
, vol.80
, Issue.2
, pp. 225-236
-
-
Hunter, T.1
-
68
-
-
0034662928
-
A distinctive role for the Yersinia protein kinase: Actin binding, kinase activation, and cytoskeleton disruption
-
Juris SJ, Rudolph AE, Huddler D, Orth K, Dixon JE. A distinctive role for the Yersinia protein kinase: actin binding, kinase activation, and cytoskeleton disruption. Proc. Natl Acad. Sci. USA 97(17), 9431-9436 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, Issue.17
, pp. 9431-9436
-
-
Juris, S.J.1
Rudolph, A.E.2
Huddler, D.3
Orth, K.4
Dixon, J.E.5
-
69
-
-
29344445221
-
Identification of otubain 1 as a novel substrate for the Yersinia protein kinase using chemical genetics and mass spectrometry
-
Juris SJ, Shah K, Shokat K, Dixon JE, Vacratsis PO. Identification of otubain 1 as a novel substrate for the Yersinia protein kinase using chemical genetics and mass spectrometry. FEBS Lett. 580(1), 179-183 (2006).
-
(2006)
FEBS Lett.
, vol.580
, Issue.1
, pp. 179-183
-
-
Juris, S.J.1
Shah, K.2
Shokat, K.3
Dixon, J.E.4
Vacratsis, P.O.5
-
70
-
-
81255205278
-
Extensive recombination events and horizontal gene transfer shaped the Legionella pneumophila genomes
-
Gomez-Valero L, Rusniok C, Jarraud S et al. Extensive recombination events and horizontal gene transfer shaped the Legionella pneumophila genomes. BMC Genomics 12, 536 (2011).
-
(2011)
BMC Genomics
, vol.12
, pp. 536
-
-
Gomez-Valero, L.1
Rusniok, C.2
Jarraud, S.3
-
71
-
-
69549133937
-
A Legionella type IV effector activates the NF-kappaB pathway by phosphorylating the IkappaB family of inhibitors
-
Ge J, Xu H, Li T et al. A Legionella type IV effector activates the NF-kappaB pathway by phosphorylating the IkappaB family of inhibitors. Proc. Natl Acad. Sci. USA 106(33), 13725-13730 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, Issue.33
, pp. 13725-13730
-
-
Ge, J.1
Xu, H.2
Li, T.3
-
72
-
-
0036009115
-
NF-kappaB at the crossroads of life and death
-
Karin M, Lin A. NF-kappaB at the crossroads of life and death. Nat. Immunol. 3(3), 221-227 (2002).
-
(2002)
Nat. Immunol.
, vol.3
, Issue.3
, pp. 221-227
-
-
Karin, M.1
Lin, A.2
-
73
-
-
72749121799
-
Temporal resolution of two-tracked NF-kappaB activation by Legionella pneumophila
-
Bartfeld S, Engels C, Bauer B et al. Temporal resolution of two-tracked NF-kappaB activation by Legionella pneumophila. Cell. Microbiol. 11(11), 1638-1651 (2009).
-
(2009)
Cell. Microbiol.
, vol.11
, Issue.11
, pp. 1638-1651
-
-
Bartfeld, S.1
Engels, C.2
Bauer, B.3
-
74
-
-
77957137443
-
LnaB: A Legionella pneumophila activator of NF-kappaB
-
Losick VP, Haenssler E, Moy MY, Isberg RR. LnaB: a Legionella pneumophila activator of NF-kappaB. Cell. Microbiol. 12(8), 1083-1097 (2010).
-
(2010)
Cell. Microbiol.
, vol.12
, Issue.8
, pp. 1083-1097
-
-
Losick, V.P.1
Haenssler, E.2
Moy, M.Y.3
Isberg, R.R.4
-
75
-
-
79955585865
-
Protein kinase LegK2 is a type IV secretion system effector involved in endoplasmic reticulum recruitment and intracellular replication of Legionella pneumophila
-
Hervet E, Charpentier X, Vianney A et al. Protein kinase LegK2 is a type IV secretion system effector involved in endoplasmic reticulum recruitment and intracellular replication of Legionella pneumophila. Infect. Immun. 79(5), 1936-1950 (2011).
-
(2011)
Infect. Immun.
, vol.79
, Issue.5
, pp. 1936-1950
-
-
Hervet, E.1
Charpentier, X.2
Vianney, A.3
-
76
-
-
83655174194
-
Control of host cell phosphorylation by Legionella pneumophila
-
Comprehensive review on how Legionella pneumophila controls host functions through phosphorylation of host proteins
-
Haenssler E, Isberg RR. Control of host cell phosphorylation by Legionella pneumophila. Front. Microbiol. 2, 64 (2011). Comprehensive review on how Legionella pneumophila controls host functions through phosphorylation of host proteins.
-
(2011)
Front. Microbiol.
, vol.2
, pp. 64
-
-
Haenssler, E.1
Isberg, R.R.2
-
77
-
-
49449087287
-
Glycosyltransferases: Structures, functions, and mechanisms
-
Lairson LL, Henrissat B, Davies GJ, Withers SG. Glycosyltransferases: structures, functions, and mechanisms. Annu. Rev. Biochem. 77, 521-555 (2008).
-
(2008)
Annu. Rev. Biochem.
, vol.77
, pp. 521-555
-
-
Lairson, L.L.1
Henrissat, B.2
Davies, G.J.3
Withers, S.G.4
-
78
-
-
42749095602
-
Structure and mode of action of clostridial glucosylating toxins: The ABCD model
-
Jank T, Aktories K. Structure and mode of action of clostridial glucosylating toxins: the ABCD model. Trends Microbiol. 16(5), 222-229 (2008).
-
(2008)
Trends Microbiol.
, vol.16
, Issue.5
, pp. 222-229
-
-
Jank, T.1
Aktories, K.2
-
79
-
-
0037222925
-
Purification and characterization of a UDP-glucosyltransferase produced by Legionella pneumophila
-
Belyi I, Popoff MR, Cianciotto NP. Purification and characterization of a UDP-glucosyltransferase produced by Legionella pneumophila. Infect. Immun. 71(1), 181-186 (2003).
-
(2003)
Infect. Immun.
, vol.71
, Issue.1
, pp. 181-186
-
-
Belyi, I.1
Popoff, M.R.2
Cianciotto, N.P.3
-
80
-
-
33750944019
-
Legionella pneumophila glucosyltransferase inhibits host elongation factor 1A
-
Belyi Y, Niggeweg R, Opitz B et al. Legionella pneumophila glucosyltransferase inhibits host elongation factor 1A. Proc. Natl Acad. Sci. USA 103(45), 16953-16958 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, Issue.45
, pp. 16953-16958
-
-
Belyi, Y.1
Niggeweg, R.2
Opitz, B.3
-
81
-
-
77954377942
-
EEF1A: Thinking outside the ribosome
-
Mateyak MK, Kinzy TG. eEF1A: thinking outside the ribosome. J. Biol. Chem. 285(28), 21209-21213 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, Issue.28
, pp. 21209-21213
-
-
Mateyak, M.K.1
Kinzy, T.G.2
-
82
-
-
79959213985
-
Bacterial protein toxins that modify host regulatory GTPases
-
Aktories K. Bacterial protein toxins that modify host regulatory GTPases. Nat. Rev. Microbiol. 9(7), 487-498 (2011).
-
(2011)
Nat. Rev. Microbiol.
, vol.9
, Issue.7
, pp. 487-498
-
-
Aktories, K.1
-
83
-
-
41949084350
-
Lgt: A family of cytotoxic glucosyltransferases produced by Legionella pneumophila
-
Belyi Y, Tabakova I, Stahl M, Aktories K. Lgt: a family of cytotoxic glucosyltransferases produced by Legionella pneumophila. J. Bacteriol. 190(8), 3026-3035 (2008).
-
(2008)
J. Bacteriol.
, vol.190
, Issue.8
, pp. 3026-3035
-
-
Belyi, Y.1
Tabakova, I.2
Stahl, M.3
Aktories, K.4
-
84
-
-
65549084822
-
Targeting eEF1A by a Legionella pneumophila effector leads to inhibition of protein synthesis and induction of host stress response
-
Shen X, Banga S, Liu Y et al. Targeting eEF1A by a Legionella pneumophila effector leads to inhibition of protein synthesis and induction of host stress response. Cell. Microbiol. 11(6), 911-926 (2009).
-
(2009)
Cell. Microbiol.
, vol.11
, Issue.6
, pp. 911-926
-
-
Shen, X.1
Banga, S.2
Liu, Y.3
-
85
-
-
79952203418
-
Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila
-
Fontana MF, Banga S, Barry KC et al. Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila. PLoS Pathog. 7(2), E1001289 (2011).
-
(2011)
PLoS Pathog.
, vol.7
, Issue.2
-
-
Fontana, M.F.1
Banga, S.2
Barry, K.C.3
-
86
-
-
83755222623
-
Innate immunity to Legionella pneumophila
-
Massis LM, Zamboni DS. Innate immunity to Legionella pneumophila. Front. Microbiol. 2, 109 (2011).
-
(2011)
Front. Microbiol.
, vol.2
, pp. 109
-
-
Massis, L.M.1
Zamboni, D.S.2
-
88
-
-
63649139064
-
The fic domain: Regulation of cell signaling by adenylylation
-
Worby CA, Mattoo S, Kruger RP et al. The fic domain: regulation of cell signaling by adenylylation. Mol. Cell 34(1), 93-103 (2009).
-
(2009)
Mol. Cell
, vol.34
, Issue.1
, pp. 93-103
-
-
Worby, C.A.1
Mattoo, S.2
Kruger, R.P.3
-
89
-
-
58149400542
-
AMPylation of Rho GTPases by Vibrio VopS disrupts effector binding and downstream signaling
-
Yarbrough ML, Li Y, Kinch LN, Grishin NV, Ball HL, Orth K. AMPylation of Rho GTPases by Vibrio VopS disrupts effector binding and downstream signaling. Science 323(5911), 269-272 (2009).
-
(2009)
Science
, vol.323
, Issue.5911
, pp. 269-272
-
-
Yarbrough, M.L.1
Li, Y.2
Kinch, L.N.3
Grishin, N.V.4
Ball, H.L.5
Orth, K.6
-
90
-
-
66149098151
-
Bacterial Fic proteins AMP up infection
-
Comprehensive review on the function of Fic domain proteins of different bacterial pathogens
-
Roy CR, Mukherjee S. Bacterial Fic proteins AMP up infection. Sci. Signal. 2(62), PE14 (2009). Comprehensive review on the function of Fic domain proteins of different bacterial pathogens.
-
(2009)
Sci. Signal.
, vol.2
, Issue.62
-
-
Roy, C.R.1
Mukherjee, S.2
-
91
-
-
77955872117
-
The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b
-
First report that the L. pneumophila effector DrrA (SidM) has AMPylation activity towards Rab
-
Müller MP, Peters H, Blümer J, Blankenfeldt W, Goody RS, Itzen A. The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b. Science 329(5994), 946-949 (2010). First report that the L. pneumophila effector DrrA (SidM) has AMPylation activity towards Rab.
-
(2010)
Science
, vol.329
, Issue.5994
, pp. 946-949
-
-
Müller, M.P.1
Peters, H.2
Blümer, J.3
Blankenfeldt, W.4
Goody, R.S.5
Itzen, A.6
-
92
-
-
64149084796
-
Rab1 guanine nucleotide exchange factor SidM is a major phosphatidylinositol 4-phosphate-binding effector protein of Legionella pneumophila
-
Brombacher E, Urwyler S, Ragaz C et al. Rab1 guanine nucleotide exchange factor SidM is a major phosphatidylinositol 4-phosphate-binding effector protein of Legionella pneumophila. J. Biol. Chem. 284(8), 4846-4856 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, Issue.8
, pp. 4846-4856
-
-
Brombacher, E.1
Urwyler, S.2
Ragaz, C.3
-
93
-
-
0030920782
-
G protein mechanisms: Insights from structural analysis
-
Sprang SR. G protein mechanisms: insights from structural analysis. Annu. Rev. Biochem. 66, 639-678 (1997).
-
(1997)
Annu. Rev. Biochem.
, vol.66
, pp. 639-678
-
-
Sprang, S.R.1
-
94
-
-
36249027095
-
Legionella pneumophila proteins that regulate Rab1 membrane cycling
-
Demonstrates that DrrA (SidM) of L. pneumophila functions as both a GDP-dissociation inhibitor-displacement factor and a nucleotide exchange factor for Rab
-
Ingmundson A, Delprato A, Lambright DG, Roy CR. Legionella pneumophila proteins that regulate Rab1 membrane cycling. Nature 450(7168), 365-369 (2007). Demonstrates that DrrA (SidM) of L. pneumophila functions as both a GDP-dissociation inhibitor-displacement factor and a nucleotide exchange factor for Rab.
-
(2007)
Nature
, vol.450
, Issue.7168
, pp. 365-369
-
-
Ingmundson, A.1
Delprato, A.2
Lambright, D.G.3
Roy, C.R.4
-
95
-
-
84889234796
-
A bifunctional bacterial protein links GDI displacement to Rab1 activation
-
Demonstrates that DrrA (SidM) of L. pneumophila functions as both a GDI-displacement factor and a nucleotide exchange factor for Rab
-
Machner MP, Isberg RR. A bifunctional bacterial protein links GDI displacement to Rab1 activation. Science 318(5852), 974-977 (2007). Demonstrates that DrrA (SidM) of L. pneumophila functions as both a GDI-displacement factor and a nucleotide exchange factor for Rab.
-
(2007)
Science
, vol.318
, Issue.5852
, pp. 974-977
-
-
Machner, M.P.1
Isberg, R.R.2
-
96
-
-
72449132474
-
RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity
-
Schoebel S, Oesterlin LK, Blankenfeldt W, Goody RS, Itzen A. RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity. Mol. Cell 36(6), 1060-1072 (2009).
-
(2009)
Mol. Cell
, vol.36
, Issue.6
, pp. 1060-1072
-
-
Schoebel, S.1
Oesterlin, L.K.2
Blankenfeldt, W.3
Goody, R.S.4
Itzen, A.5
-
97
-
-
79960699136
-
De-AMPylation of the small GTPase Rab1 by the Pathogen Legionella pneumophila
-
First description of a L. pneumophila effector that encodes de-AMPylation activity towards Rab
-
Neunuebel MR, Chen Y, Gaspar AH, Backlund PS Jr, Yergey A, Machner MP. De-AMPylation of the small GTPase Rab1 by the Pathogen Legionella pneumophila. Science 333(6041), 453-456 (2011). First description of a L. pneumophila effector that encodes de-AMPylation activity towards Rab.
-
(2011)
Science
, vol.333
, Issue.6041
, pp. 453-456
-
-
Neunuebel, M.R.1
Chen, Y.2
Gaspar, A.H.3
Backlund Jr., P.S.4
Yergey, A.5
Machner, M.P.6
-
98
-
-
79960929331
-
Legionella pneumophila SidD is a deAMPylase that modifies Rab1
-
First description of a L. pneumophila effector that encodes de-AMPylation activity towards Rab
-
Tan Y, Luo ZQ. Legionella pneumophila SidD is a deAMPylase that modifies Rab1. Nature 475(7357), 506-509 (2011). First description of a L. pneumophila effector that encodes de-AMPylation activity towards Rab.
-
(2011)
Nature
, vol.475
, Issue.7357
, pp. 506-509
-
-
Tan, Y.1
Luo, Z.Q.2
-
99
-
-
2442537071
-
Legionella subvert the functions of Rab1 and Sec22b to create a replicative organelle
-
Kagan JC, Stein MP, Pypaert M, Roy CR. Legionella subvert the functions of Rab1 and Sec22b to create a replicative organelle. J. Exp. Med. 199(9), 1201-1211 (2004).
-
(2004)
J. Exp. Med.
, vol.199
, Issue.9
, pp. 1201-1211
-
-
Kagan, J.C.1
Stein, M.P.2
Pypaert, M.3
Roy, C.R.4
-
100
-
-
2142758690
-
Legionella pneumophila replication vacuole formation involves rapid recruitment of proteins of the early secretory system
-
Derré I, Isberg RR. Legionella pneumophila replication vacuole formation involves rapid recruitment of proteins of the early secretory system. Infect. Immun. 72(5), 3048-3053 (2004).
-
(2004)
Infect. Immun.
, vol.72
, Issue.5
, pp. 3048-3053
-
-
Derré, I.1
Isberg, R.R.2
-
101
-
-
80052271972
-
Identification and modelling of a PPM protein phosphatase fold in the Legionella pneumophila deAMPylase SidD
-
Rigden DJ. Identification and modelling of a PPM protein phosphatase fold in the Legionella pneumophila deAMPylase SidD. FEBS Lett. 585(17), 2749-2754 (2011).
-
(2011)
FEBS Lett.
, vol.585
, Issue.17
, pp. 2749-2754
-
-
Rigden, D.J.1
-
102
-
-
67149136177
-
Fido, a novel AMPylation domain common to fic, doc, and AvrB
-
Kinch LN, Yarbrough ML, Orth K, Grishin NV. Fido, a novel AMPylation domain common to fic, doc, and AvrB. PLoS One 4(6), E5818 (2009).
-
(2009)
PLoS One
, vol.4
, Issue.6
-
-
Kinch, L.N.1
Yarbrough, M.L.2
Orth, K.3
Grishin, N.V.4
-
103
-
-
0025861991
-
Functional analysis of the fic gene involved in regulation of cell division
-
Komano T, Utsumi R, Kawamukai M. Functional analysis of the fic gene involved in regulation of cell division. Res. Microbiol. 142(2-3), 269-277 (1991).
-
(1991)
Res. Microbiol.
, vol.142
, Issue.2-3
, pp. 269-277
-
-
Komano, T.1
Utsumi, R.2
Kawamukai, M.3
-
104
-
-
77951248403
-
Histophilus somni IbpA DR2/Fic in virulence and immunoprotection at the natural host alveolar epithelial barrier
-
Zekarias B, Mattoo S, Worby C, Lehmann J, Rosenbusch RF, Corbeil LB. Histophilus somni IbpA DR2/Fic in virulence and immunoprotection at the natural host alveolar epithelial barrier. Infect. Immun. 78(5), 1850-1858 (2010).
-
(2010)
Infect. Immun.
, vol.78
, Issue.5
, pp. 1850-1858
-
-
Zekarias, B.1
Mattoo, S.2
Worby, C.3
Lehmann, J.4
Rosenbusch, R.F.5
Corbeil, L.B.6
-
105
-
-
79952128780
-
Fic domain-catalyzed adenylylation: Insight provided by the structural analysis of the type IV secretion system effector BepA
-
Palanivelu DV, Goepfert A, Meury M, Guye P, Dehio C, Schirmer T. Fic domain-catalyzed adenylylation: insight provided by the structural analysis of the type IV secretion system effector BepA. Protein Sci. 20(3), 492-499 (2011).
-
(2011)
Protein Sci.
, vol.20
, Issue.3
, pp. 492-499
-
-
Palanivelu, D.V.1
Goepfert, A.2
Meury, M.3
Guye, P.4
Dehio, C.5
Schirmer, T.6
-
106
-
-
46249111623
-
Ankyrin repeat proteins comprise a diverse family of bacterial type IV effectors
-
Analysis of ankyrin motif proteins of L. pneumophila and Coxiella burnetti showing that they are secreted bacterial effectors that modulate host cell functions
-
Pan X, Lührmann A, Satoh A, Laskowski-Arce MA, Roy CR. Ankyrin repeat proteins comprise a diverse family of bacterial type IV effectors. Science 320(5883), 1651-1654 (2008). Analysis of ankyrin motif proteins of L. pneumophila and Coxiella burnetti showing that they are secreted bacterial effectors that modulate host cell functions.
-
(2008)
Science
, vol.320
, Issue.5883
, pp. 1651-1654
-
-
Pan, X.1
Lührmann, A.2
Satoh, A.3
Laskowski-Arce, M.A.4
Roy, C.R.5
-
107
-
-
80052399642
-
Modulation of Rab GTPase function by a protein phosphocholine transferase
-
Describes for the first time phosphocholination of Rab by a bacterial effector
-
Mukherjee S, Liu X, Arasaki K, Mcdonough J, Galán JE, Roy CR. Modulation of Rab GTPase function by a protein phosphocholine transferase. Nature 477(7362), 103-106 (2011). Describes for the first time phosphocholination of Rab by a bacterial effector.
-
(2011)
Nature
, vol.477
, Issue.7362
, pp. 103-106
-
-
Mukherjee, S.1
Liu, X.2
Arasaki, K.3
Mcdonough, J.4
Galán, J.E.5
Roy, C.R.6
-
108
-
-
84855504174
-
Legionella pneumophila regulates the small GTPase Rab1 activity by reversible phosphorylcholination
-
Describes for the first time the dephosphorylcholinate activity of a bacterial effector
-
Tan Y, Arnold RJ, Luo ZQ. Legionella pneumophila regulates the small GTPase Rab1 activity by reversible phosphorylcholination. Proc. Natl Acad. Sci. USA 108(52), 21212-21217 (2011). Describes for the first time the dephosphorylcholinate activity of a bacterial effector.
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, Issue.52
, pp. 21212-21217
-
-
Tan, Y.1
Arnold, R.J.2
Luo, Z.Q.3
-
109
-
-
84858067652
-
Bacterial effector-involved temporal and spatial regulation by hijack of the host ubiquitin pathway
-
Kubori T, Nagai A. Bacterial effector-involved temporal and spatial regulation by hijack of the host ubiquitin pathway. Front. Microbiol. 2, 145 (2011).
-
(2011)
Front. Microbiol.
, vol.2
, pp. 145
-
-
Kubori, T.1
Nagai, A.2
|