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Volumn 90, Issue 3, 2012, Pages 317-325

Advances and applications of induced pluripotent stem cells

Author keywords

Drug discovery; Ips; Regenerative medicine; Retrovirus

Indexed keywords

ADENOVIRUS VECTOR; MESSENGER RNA; MICRORNA; TRANSCRIPTION FACTOR;

EID: 84858023837     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/y11-125     Document Type: Article
Times cited : (14)

References (83)
  • 1
    • 55749089875 scopus 로고    scopus 로고
    • Efficient and rapid generation of induced pluripotent stem cells from human keratinocyte
    • doi:10.1038/nbt.1503
    • Aasen, T., Raya, A., Barrero, M.J., Garreta, E., Consiglio, A., Gonzalez, F., et al. 2008. Efficient and rapid generation of induced pluripotent stem cells from human keratinocyte. Nat. Biotechnol. 26(11): 1276-1284. doi:10.1038/nbt.1503.
    • (2008) Nat. Biotechnol. , vol.26 , Issue.11 , pp. 1276-1284
    • Aasen, T.1    Raya, A.2    Barrero, M.J.3    Garreta, E.4    Consiglio, A.5    Gonzalez, F.6
  • 2
    • 79953881831 scopus 로고    scopus 로고
    • Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency
    • doi:10.1016/j.stem.2011.03.001
    • Anokye-Danso, F., Trivedi, C.M., Juhr, D., Gupta, M., Cui, Z., Tian, Y., et al. 2011. Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. Cell Stem Cell, 8(4): 376-388. doi:10.1016/j.stem.2011.03.001.
    • (2011) Cell Stem Cell , vol.8 , Issue.4 , pp. 376-388
    • Anokye-Danso, F.1    Trivedi, C.M.2    Juhr, D.3    Gupta, M.4    Cui, Z.5    Tian, Y.6
  • 3
    • 41949134533 scopus 로고    scopus 로고
    • Generation of pluripotent stem cells from adult mouse liver and stomach cells
    • doi:10.1126/science.1154884
    • Aoi, T., Yae, K., Nakagawa, M., Ichisaka, T., Okita, K., Takahashi, K., et al. 2008. Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science, 321(5889): 699-702. doi:10.1126/science.1154884.
    • (2008) Science , vol.321 , Issue.5889 , pp. 699-702
    • Aoi, T.1    Yae, K.2    Nakagawa, M.3    Ichisaka, T.4    Okita, K.5    Takahashi, K.6
  • 4
    • 77954462722 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells from human adipose-derived stem cells without c-MYC
    • doi:10.1089/ten.tea.2009.0747
    • Aoki, T., Ohnishi, H., Oda, Y., Tadokoro, M., Sasao, M., Kato, H., et al. 2010. Generation of induced pluripotent stem cells from human adipose-derived stem cells without c-MYC. Tissue Eng. Part A, 16 (7): 2197-2206. doi:10.1089/ten.tea.2009.0747.
    • (2010) Tissue Eng. Part A. , vol.16 , Issue.7 , pp. 2197-2206
    • Aoki, T.1    Ohnishi, H.2    Oda, Y.3    Tadokoro, M.4    Sasao, M.5    Kato, H.6
  • 5
    • 77956265725 scopus 로고    scopus 로고
    • Induced pluripotent stem cells: A new era for hepatology
    • doi:10.1016/j.jhep.2010.05.009
    • Asgari, S., Pournasr, B., Salekdeh, G.H., Ghodsizadeh, A., Ott, M., and Baharvand, H. 2010. Induced pluripotent stem cells: a new era for hepatology. J. Hepatol. 53(4): 738-751. doi:10.1016/j.jhep.2010.05.009.
    • (2010) J. Hepatol. , vol.53 , Issue.4 , pp. 738-751
    • Asgari, S.1    Pournasr, B.2    Salekdeh, G.H.3    Ghodsizadeh, A.4    Ott, M.5    Baharvand, H.6
  • 6
    • 79959992876 scopus 로고    scopus 로고
    • Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells
    • doi:10.1016/j.stem.2011.06.007
    • Bar-Nur, O., Russ, H.A., Efrat, S., and Benvenisty, N. 2011. Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells. Cell Stem Cell. 9: 17-23. doi:10.1016/j.stem.2011.06.007.
    • (2011) Cell Stem Cell , vol.9 , pp. 17-23
    • Bar-Nur, O.1    Russ, H.A.2    Efrat, S.3    Benvenisty, N.4
  • 7
    • 79551665440 scopus 로고    scopus 로고
    • A functionally characterized test set of human induced pluripotent stem cells
    • doi:10.1038/nbt.1783
    • Boulting, G.L., Kiskinis, E., Croft, G.F., Amoroso, M.W., Oakley, D. H., Wainger, B.J., et al. 2011. A functionally characterized test set of human induced pluripotent stem cells. Nat. Biotechnol. 29(3): 279-286. doi:10.1038/nbt.1783.
    • (2011) Nat. Biotechnol. , vol.29 , Issue.3 , pp. 279-286
    • Boulting, G.L.1    Kiskinis, E.2    Croft, G.F.3    Amoroso, M.W.4    Oakley, D.H.5    Wainger, B.J.6
  • 8
    • 0000042464 scopus 로고
    • Transplantation of living nuclei from blastula cells into enucleated frogs' eggs
    • doi:10.1073/pnas.38.5.455
    • Briggs, R., and King, T.J. 1952. Transplantation of living nuclei from blastula cells into enucleated frogs' eggs. Proc. Natl. Acad. Sci. U.S. A. 38(5): 455-463. doi:10.1073/pnas.38.5.455.
    • (1952) Proc. Natl. Acad. Sci. U.S. A. , vol.38 , Issue.5 , pp. 455-463
    • Briggs, R.1    King, T.J.2
  • 9
    • 79958149493 scopus 로고    scopus 로고
    • MicroRNAs and reprogramming
    • doi:10.1038/nbt.1889
    • Chang, H.M., and Gregory, R.I. 2011. MicroRNAs and reprogramming. Nat. Biotechnol. 29(6): 499-500. doi:10.1038/nbt.1889.
    • (2011) Nat. Biotechnol. , vol.29 , Issue.6 , pp. 499-500
    • Chang, H.M.1    Gregory, R.I.2
  • 10
    • 66149165885 scopus 로고    scopus 로고
    • Polycistronic lentiviral vector for "hit and run" reprogramming of adult skin fibroblasts to induced pluripotent stem cells
    • doi:10.1002/stem.39
    • Chang, C.W., Lai, Y.S., Pawlik, K.M., Liu, K., Sun, C.W., Li, C., et al. 2009. Polycistronic lentiviral vector for "hit and run" reprogramming of adult skin fibroblasts to induced pluripotent stem cells. Stem Cells, 27(5): 1042-1049. doi:10.1002/stem.39.
    • (2009) Stem Cells , vol.27 , Issue.5 , pp. 1042-1049
    • Chang, C.W.1    Lai, Y.S.2    Pawlik, K.M.3    Liu, K.4    Sun, C.W.5    Li, C.6
  • 11
    • 79952536226 scopus 로고    scopus 로고
    • Efficient human iPS cell derivation by a nonintegrating plasmid from blood cells with unique epigenetic and gene expression signatures
    • doi:10. 1038/cr.2011.12
    • Chou, B.K., Mali, P., Huang, X., Ye, Z., Dowey, S.N., Resar, L.M.S., et al. 2011. Efficient human iPS cell derivation by a nonintegrating plasmid from blood cells with unique epigenetic and gene expression signatures. Cell Res. 21(3): 518-529. doi:10. 1038/cr.2011.12.
    • (2011) Cell Res , Issue.3 , pp. 518-529
    • Chou, B.K.1    Mali, P.2    Huang, X.3    Ye, Z.4    Dowey, S.N.5    Resar, L.M.S.6
  • 12
    • 79952900560 scopus 로고    scopus 로고
    • Turning straw into gold: Directing cell fate for regenerative medicine
    • doi:10.1038/nrg2938
    • Cohen, D.E., and Melton, D. 2011. Turning straw into gold: directing cell fate for regenerative medicine. Nat. Rev. Genet. 12(4): 243-252. doi:10.1038/nrg2938.
    • (2011) Nat. Rev. Genet. , vol.12 , Issue.4 , pp. 243-252
    • Cohen, D.E.1    Melton, D.2
  • 13
    • 0023663888 scopus 로고
    • Expression of a single transfected cDNA converts fibroblasts to myoblasts
    • doi:10.1016/0092-8674(87)90585-X3690668
    • Davis, R.L., Weintraub, H., and Lassar, A.B. 1987. Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell, 51(6): 987-1000. doi:10.1016/0092-8674(87)90585-X3690668.
    • (1987) Cell , vol.51 , Issue.6 , pp. 987-1000
    • Davis, R.L.1    Weintraub, H.2    Lassar, A.B.3
  • 14
    • 50149098605 scopus 로고    scopus 로고
    • Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
    • doi:10.1126/science.1158799
    • Dimos, J.T., Rodolfa, K.T., Niakan, K.K., Weisenthal, L.M., Mitsumoto, H., Chung, W., et al. 2008. Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science, 321(5893): 1218-1221. doi:10.1126/science.1158799.
    • (2008) Science , vol.321 , Issue.5893 , pp. 1218-1221
    • Dimos, J.T.1    Rodolfa, K.T.2    Niakan, K.K.3    Weisenthal, L.M.4    Mitsumoto, H.5    Chung, W.6
  • 15
    • 23744479962 scopus 로고    scopus 로고
    • Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice
    • doi:10.1016/j.cell.2005.07.013
    • Ding, S., Wu, X., Li, G., Han, M., Zhuang, Y., and Xu, T. 2005. Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice. Cell, 122(3): 473-483. doi:10.1016/j.cell.2005.07.013.
    • (2005) Cell , vol.122 , Issue.3 , pp. 473-483
    • Ding, S.1    Wu, X.2    Li, G.3    Han, M.4    Zhuang, Y.5    Xu, T.6
  • 16
    • 58249110796 scopus 로고    scopus 로고
    • Induced pluripotent stem cells from a spinal muscular atrophy patient
    • doi:10.1038/nature07677
    • Ebert, A.D., Yu, J., Rose, F.F., Jr, Mattis, V.B., Lorson, C.L., Thomson, J.A., and Svendsen, C.N. 2009. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature, 457 (7227): 277-280. doi:10.1038/nature07677.
    • (2009) Nature , vol.457 , Issue.7227 , pp. 277-280
    • Ebert, A.D.1    Yu, J.2    Rose Jr., F.F.3    Mattis, V.B.4    Lorson, C.L.5    Thomson, J.A.6    Svendsen, C.N.7
  • 17
    • 55049122748 scopus 로고    scopus 로고
    • Reprogramming of neural progenitor cells into induced pluripotent stem cells in the absence of exogenous Sox2 expression
    • doi:10.1634/stemcells.2008-0317
    • Eminli, S., Utikal, J., Arnold, K., Jaenisch, R., and Hochedlinger, K. 2008. Reprogramming of neural progenitor cells into induced pluripotent stem cells in the absence of exogenous Sox2 expression. Stem Cells, 26(10): 2467-2474. doi:10.1634/stemcells.2008-0317.
    • (2008) Stem Cells , vol.26 , Issue.10 , pp. 2467-2474
    • Eminli, S.1    Utikal, J.2    Arnold, K.3    Jaenisch, R.4    Hochedlinger, K.5
  • 19
    • 80052547572 scopus 로고    scopus 로고
    • Human iPSC and ESC translation potential debated
    • doi:10.1038/nbt0511-375a
    • Fox, J.L. 2011. Human iPSC and ESC translation potential debated. Nat. Biotechnol. 29(5): 375-376. doi:10.1038/nbt0511-375a.
    • (2011) Nat. Biotechnol. , vol.29 , Issue.5 , pp. 375-376
    • Fox, J.L.1
  • 20
    • 0030152925 scopus 로고    scopus 로고
    • Precise excision of TTAA-specific lepidopteran transposons piggyback (IFP2) and tagalong (TFP3) from the baculovirus genome in cell lines from two species of Lepidoptera
    • doi:10.1111/j.1365-2583.1996.tb00048.x
    • Fraser, M.J., Ciszczon, T., Elick, T., and Bauser, C. 1996. Precise excision of TTAA-specific lepidopteran transposons piggyback (IFP2) and tagalong (TFP3) from the baculovirus genome in cell lines from two species of Lepidoptera. Insect Mol. Biol. 5(2): 141-151. doi:10.1111/j.1365-2583.1996.tb00048.x.
    • (1996) Insect Mol Biol , vol.5 , Issue.2 , pp. 141-151
    • Fraser, M.J.1    Ciszczon, T.2    Elick, T.3    Bauser, C.4
  • 21
    • 70450265981 scopus 로고    scopus 로고
    • Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome
    • doi:10.2183/pjab.85.348
    • Fusaki, N., Ban, H., Nishiyama, A., Saeki, K., and Hasegawa, M. 2009. Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome. Proc. Jpn. Acad B Phys. Biol. Sci. 85(8): 348-362. doi:10.2183/pjab.85.348.
    • (2009) Proc. Jpn. Acad B Phys. Biol. Sci. , vol.85 , Issue.8 , pp. 348-362
    • Fusaki, N.1    Ban, H.2    Nishiyama, A.3    Saeki, K.4    Hasegawa, M.5
  • 22
    • 68949164755 scopus 로고    scopus 로고
    • Chd1 regulates open chromatin and pluripotency of embryonic stem cells
    • Gaspar-Maia, A., Alajem, A., Polesso, F., Sridharan, R., Mason, M.J., Heidersbach, A., et al. 2009. Chd1 regulates open chromatin and pluripotency of embryonic stem cells. Nature, 460(7257): 863-868.
    • (2009) Nature , vol.460 , Issue.7257 , pp. 863-868
    • Gaspar-Maia, A.1    Alajem, A.2    Polesso, F.3    Sridharan, R.4    Mason, M.J.5    Heidersbach, A.6
  • 23
    • 78650467973 scopus 로고    scopus 로고
    • Open chromatin in pluripotency and reprogramming
    • doi:10.1038/nrm3036.21179060
    • Gaspar-Maia, A., Alajem, A., Meshorer, E., and Ramalho-Santos, M. 2011. Open chromatin in pluripotency and reprogramming. Nat. Rev. Mol. Cell Biol. 12(1): 36-47. doi:10.1038/nrm3036.21179060.
    • (2011) Nat. Rev. Mol. Cell Biol. , vol.12 , Issue.1 , pp. 36-47
    • Gaspar-Maia, A.1    Alajem, A.2    Meshorer, E.3    Ramalho-Santos, M.4
  • 24
    • 78650343117 scopus 로고    scopus 로고
    • Induced pluripotent stem cell-derived human platelets: One step closer to the clinic
    • doi:10.1084/jem.20102428
    • Gekas, C., and Graf, T. 2010. Induced pluripotent stem cell-derived human platelets: one step closer to the clinic. J. Exp. Med. 207 (13): 2781-2784. doi:10.1084/jem.20102428.
    • (2010) J. Exp. Med. , vol.207 , Issue.13 , pp. 2781-2784
    • Gekas, C.1    Graf, T.2
  • 25
    • 67049155513 scopus 로고    scopus 로고
    • Generation of mouse-induced pluripotent stem cells by transient expression of a single nonviral polycistronic vector
    • doi:10.1073/pnas.0901471106.19458047
    • González, F., Barragan Monasterio, M., Tiscornia, G., Montserrat Pulido, N., Vassena, R., Batlle Morera, L., et al. 2009. Generation of mouse-induced pluripotent stem cells by transient expression of a single nonviral polycistronic vector. Proc. Natl. Acad. Sci. U.S. A. 106(22): 8918-8922. doi:10.1073/pnas.0901471106.19458047.
    • (2009) Proc. Natl. Acad. Sci. U.S. A. , vol.106 , Issue.22 , pp. 8918-8922
    • González, F.1    Barragan, M.M.2    Tiscornia, G.3    Montserrat, P.N.4    Vassena, R.5    Batlle, M.L.6
  • 26
    • 79952899995 scopus 로고    scopus 로고
    • Methods for making induced pluripotent stem cells: Reprogramming à la carte
    • doi:10.1038/nrg2937.21339765
    • González, F., Boué, S., and Izpisúa Belmonte, J.C. 2011. Methods for making induced pluripotent stem cells: reprogramming à la carte. Nat. Rev. Genet. 12(4): 231-242. doi:10.1038/nrg2937.21339765.
    • (2011) Nat. Rev. Genet. , vol.12 , Issue.4 , pp. 231-242
    • González, F.1    Boué, S.2    Izpisúa, B.J.C.3
  • 27
    • 79952258224 scopus 로고    scopus 로고
    • Somatic coding mutations in human induced pluripotent stem cells
    • doi:10.1038/nature09805
    • Gore, A., Li, Z., Fung, H., Young, J.E., Agarwal, S., Antosiewicz-Bourget, J., et al. 2011. Somatic coding mutations in human induced pluripotent stem cells. Nature, 471(7336): 63-67. doi:10.1038/nature09805.
    • (2011) Nature , vol.471 , Issue.7336 , pp. 63-67
    • Gore, A.1    Li, Z.2    Fung, H.3    Young, J.E.4    Agarwal, S.5    Antosiewicz-Bourget, J.6
  • 28
    • 0142084745 scopus 로고    scopus 로고
    • LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCIDX1
    • doi:10.1126/science.1088547
    • Hacein-Bey-Abina, S., Von Kalle, C., Schmidt, M., McCormack, M.P., Wulffraat, N., Leboulch, P., et al. 2003. LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCIDX1. Science, 302(5644): 415-419. doi:10.1126/science.1088547.
    • (2003) Science , vol.302 , Issue.5644 , pp. 415-419
    • Hacein-Bey-Abina, S.1    von Kalle, C.2    Schmidt, M.3    McCormack, M.P.4    Wulffraat, N.5    Leboulch, P.6
  • 29
    • 37549030199 scopus 로고    scopus 로고
    • Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin
    • doi:10.1126/science.1152092.18063756
    • Hanna, J., Wernig, M., Markoulaki, S., Sun, C.W., Meissner, A., Cassady, J.P., et al. 2007. Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science, 318 (5858): 1920-1923. doi:10.1126/science.1152092.18063756.
    • (2007) Science , vol.318 , Issue.5858 , pp. 1920-1923
    • Hanna, J.1    Wernig, M.2    Markoulaki, S.3    Sun, C.W.4    Meissner, A.5    Cassady, J.P.6
  • 30
    • 41949098160 scopus 로고    scopus 로고
    • Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency
    • doi:10.1016/j.cell.2008.03.028
    • Hanna, J., Markoulaki, S., Schorderet, P., Carey, B., Beard, C., Wernig, M., et al. 2008. Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency. Cell, 133(2): 250-264. doi:10.1016/j.cell.2008.03.028.
    • (2008) Cell , vol.133 , Issue.2 , pp. 250-264
    • Hanna, J.1    Markoulaki, S.2    Schorderet, P.3    Carey, B.4    Beard, C.5    Wernig, M.6
  • 31
  • 32
    • 69349100179 scopus 로고    scopus 로고
    • Suppression of induced pluripotent stem cell generation by the p53-p21 pathway
    • doi:10.1038/nature08235
    • Hong, H., Takahashi, K., Ichisaka, T., Aoi, T., Kanagawa, O., Nakagawa, M., et al. 2009. Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature, 460(7259): 1132-1135. doi:10.1038/nature08235.
    • (2009) Nature , vol.460 , Issue.7259 , pp. 1132-1135
    • Hong, H.1    Takahashi, K.2    Ichisaka, T.3    Aoi, T.4    Kanagawa, O.5    Nakagawa, M.6
  • 33
    • 77955321344 scopus 로고    scopus 로고
    • Direct reprogramming offibroblasts into functional cardiomyocytes by defined factors
    • doi:10.1016/j.cell.2010.07.002
    • Ieda, M., Fu, J.D., Delgado-Olguin, P., Vedantham, V., Hayashi, Y., Bruneau, B.G., and Srivastava, D. 2010. Direct reprogramming offibroblasts into functional cardiomyocytes by defined factors. Cell, 142(3): 375-386. doi:10.1016/j.cell.2010.07.002.
    • (2010) Cell , vol.142 , Issue.3 , pp. 375-386
    • Ieda, M.1    Fu, J.D.2    Delgado-Olguin, P.3    Vedantham, V.4    Hayashi, Y.5    Bruneau, B.G.6    Srivastava, D.7
  • 34
    • 79952446402 scopus 로고    scopus 로고
    • Modelling the long QT syndrome with induced pluripotent stem cells
    • doi:10.1038/nature09747
    • tzhaki, I., Maizels, L., Huber, I., Zwi-Dantsis, L., Caspi, O., Winterstern, A., et al. 2011. Modelling the long QT syndrome with induced pluripotent stem cells. Nature, 471(7337): 225-229. doi:10.1038/nature09747.
    • (2011) Nature , vol.471 , Issue.7337 , pp. 225-229
    • Tzhaki, I.1    Maizels, L.2    Huber, I.3    Zwi-Dantsis, L.4    Caspi, O.5    Winterstern, A.6
  • 35
    • 69349100455 scopus 로고    scopus 로고
    • Linking the p53 tumour suppressor pathway to somatic cell reprogramming
    • doi:10.1038/nature08311
    • Kawamura, T., Suzuki, J., Wang, Y.V., Menendez, S., Morera, L.B., Raya, A., et al. 2009. Linking the p53 tumour suppressor pathway to somatic cell reprogramming. Nature, 460(7259): 1140-1144.doi:10.1038/nature08311.
    • (2009) Nature , vol.460 , Issue.7259 , pp. 1140-1144
    • Kawamura, T.1    Suzuki, J.2    Wang, Y.V.3    Menendez, S.4    Morera, L.B.5    Raya, A.6
  • 36
    • 70349687407 scopus 로고    scopus 로고
    • Direct reprogramming of human neural stem cells by OCT4
    • doi:10.1038/nature08436
    • Kim, J.B., Greber, B., Araúzo-Bravo, M., Meyer, J., Park, K., Zaehres, H., and Schöler, H.R. 2009a. Direct reprogramming of human neural stem cells by OCT4. Nature, 461(7264): 649-653. doi:10.1038/nature08436.
    • (2009) Nature , vol.461 , Issue.7264 , pp. 649-653
    • Kim, J.B.1    Greber, B.2    Araúzo-Bravo, M.3    Meyer, J.4    Park, K.5    Zaehres, H.6    Schöler, H.R.7
  • 37
    • 66049143859 scopus 로고    scopus 로고
    • Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins
    • doi:10.1016/j.stem.2009.05.005.19481515
    • Kim, D., Kim, C.H., Moon, J.I., Chung, Y.G., Chang, M.Y., Han, B.S., et al. 2009b. Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell, 4(6): 472-476. doi:10.1016/j.stem.2009.05.005.19481515.
    • (2009) Cell Stem Cell , vol.4 , Issue.6 , pp. 472-476
    • Kim, D.1    Kim, C.H.2    Moon, J.I.3    Chung, Y.G.4    Chang, M.Y.5    Han, B.S.6
  • 38
    • 77955449906 scopus 로고    scopus 로고
    • Epigenetic memory in induced pluripotent stem cells
    • doi:10.1038/nature09342
    • Kim, K., Doi, A., Wen, B., Ng, K., Zhao, R., Cahan, P., et al. 2010. Epigenetic memory in induced pluripotent stem cells. Nature, 467 (7313): 285-290. doi:10.1038/nature09342.
    • (2010) Nature , vol.467 , Issue.7313 , pp. 285-290
    • Kim, K.1    Doi, A.2    Wen, B.3    Ng, K.4    Zhao, R.5    Cahan, P.6
  • 39
    • 0029066359 scopus 로고
    • GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts and erythroblasts
    • doi:10.1101/gad.9.10.1250
    • Kulessa, H., Frampton, J., and Graf, T. 1995. GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts and erythroblasts. Genes Dev. 9(10): 1250-1262. doi:10.1101/gad.9.10.1250.
    • (1995) Genes Dev , vol.9 , Issue.10 , pp. 1250-1262
    • Kulessa, H.1    Frampton, J.2    Graf, T.3
  • 40
    • 79960219150 scopus 로고    scopus 로고
    • Advancements in reprogramming strategies for the generation of induced pluripotent stem cells
    • doi:10.1007/s10815-011-9552-6
    • Lai, M.I., Wendy-Yeo, W.Y., Ramasamy, R., Nordin, N., Rosli, R., Veerakumarasivam, A., and Abdullah, S. 2011. Advancements in reprogramming strategies for the generation of induced pluripotent stem cells. J. Assist. Reprod. Genet. 28(4): 291-301. doi:10.1007/s10815-011-9552-6.
    • (2011) J. Assist. Reprod. Genet. , vol.28 , Issue.4 , pp. 291-301
    • Lai, M.I.1    Wendy-Yeo, W.Y.2    Ramasamy, R.3    Nordin, N.4    Rosli, R.5    Veerakumarasivam, A.6    Abdullah, S.7
  • 41
    • 70349301819 scopus 로고    scopus 로고
    • Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs
    • doi:10.1038/nature08320
    • Lee, G., Papapetrou, E.P., Kim, H., Chambers, S.M., Tomishima, M.J., Fasano, C.A., et al. 2009. Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature, 461(7262): 402-406. doi:10.1038/nature08320.
    • (2009) Nature , vol.461 , Issue.7262 , pp. 402-406
    • Lee, G.1    Papapetrou, E.P.2    Kim, H.3    Chambers, S.M.4    Tomishima, M.J.5    Fasano, C.A.6
  • 42
    • 79960564360 scopus 로고    scopus 로고
    • The generation of iPS cells using non-viral magnetic nanoparticlebased transfection
    • doi:10.1016/j.biomaterials.2011.05.070
    • Lee, C.H., Kim, J.H., Lee, H.J., Jeon, K., Lim, H., Choi, H.Y., et al. 2011. The generation of iPS cells using non-viral magnetic nanoparticlebased transfection. Biomaterials, 32(28): 6683-6691. doi:10.1016/j.biomaterials.2011.05.070.
    • (2011) Biomaterials , vol.32 , Issue.28 , pp. 6683-6691
    • Lee, C.H.1    Kim, J.H.2    Lee, H.J.3    Jeon, K.4    Lim, H.5    Choi, H.Y.6
  • 43
    • 77957551870 scopus 로고    scopus 로고
    • A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts
    • doi:10.1016/j.stem.2010.04.014
    • Li, R., Liang, J., Ni, S., Zhou, T., Qing, X., Li, H., et al. 2010. A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell, 7 (1): 51-63. doi:10.1016/j.stem.2010.04.014.
    • (2010) Cell Stem Cell , vol.7 , Issue.1 , pp. 51-63
    • Li, R.1    Liang, J.2    Ni, S.3    Zhou, T.4    Qing, X.5    Li, H.6
  • 44
    • 67049164945 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells from human blood
    • doi:10.1182/blood-2009-02-204800
    • Loh, Y.H., Agarwal, S., Park, I.H., Urbach, A., Huo, H., Heffner, G., et al. 2009. Generation of induced pluripotent stem cells from human blood. Blood, 113(22): 5476-5479. doi:10.1182/blood-2009-02-204800.
    • (2009) Blood , vol.113 , Issue.22 , pp. 5476-5479
    • Loh, Y.H.1    Agarwal, S.2    Park, I.H.3    Urbach, A.4    Huo, H.5    Heffner, G.6
  • 45
    • 50849142559 scopus 로고    scopus 로고
    • A high-efficiency system for the generation and study of human induced pluripotent stem cells
    • doi:10.1016/j.stem.2008.08.003
    • Maherali, N., Ahfeldt, T., Rigamonti, A., Utikal, J., Cowan, C., and Hochedlinger, K. 2008. A high-efficiency system for the generation and study of human induced pluripotent stem cells. Cell Stem Cell, 3(3): 340-345. doi:10.1016/j.stem.2008.08.003.
    • (2008) Cell Stem Cell , vol.3 , Issue.3 , pp. 340-345
    • Maherali, N.1    Ahfeldt, T.2    Rigamonti, A.3    Utikal, J.4    Cowan, C.5    Hochedlinger, K.6
  • 46
    • 80053574096 scopus 로고    scopus 로고
    • Cardiomyocytes obtained from induced pluripotent stem cells with long-QT syndrome 3 recapitulate typical disease-specific features in vitro
    • doi:10.1161/CIRCRESAHA. 111.243139
    • Malan, D., Friedrichs, S., Fleischmann, B.K., and Sasse, P. 2011. Cardiomyocytes obtained from induced pluripotent stem cells with long-QT syndrome 3 recapitulate typical disease-specific features in vitro. Circ. Res. 109(8): 841-847. doi:10.1161/CIRCRESAHA. 111.243139.
    • (2011) Circ. Res. , vol.109 , Issue.8 , pp. 841-847
    • Malan, D.1    Friedrichs, S.2    Fleischmann, B.K.3    Sasse, P.4
  • 47
    • 77957729169 scopus 로고    scopus 로고
    • Patient-specific induced pluripotent stemcell models for long-QT syndrome
    • doi:10.1056/NEJMoa0908679
    • Moretti, A., Bellin, M., Welling, A., Jung, C.B., Lam, J.T., Bott-Flugel, L., et al. 2010. Patient-specific induced pluripotent stemcell models for long-QT syndrome. N. Engl. J. Med. 363(15): 1397-1409. doi:10.1056/NEJMoa0908679.
    • (2010) N. Engl. J. Med. , vol.363 , Issue.15 , pp. 1397-1409
    • Moretti, A.1    Bellin, M.2    Welling, A.3    Jung, C.B.4    Lam, J.T.5    Bott-Flugel, L.6
  • 48
    • 50149112857 scopus 로고    scopus 로고
    • The QT syndromes: Long and short
    • doi:10.1016/S0140-6736(08)61307-0
    • Morita, H., Wu, J., and Zipes, D.P. 2008. The QT syndromes: long and short. Lancet, 372(9640): 750-763. doi:10.1016/S0140-6736(08)61307-0.
    • (2008) Lancet , vol.372 , Issue.9640 , pp. 750-763
    • Morita, H.1    Wu, J.2    Zipes, D.P.3
  • 49
    • 79959692426 scopus 로고    scopus 로고
    • Reprogramming of somatic cells to pluripotency
    • Edited by Eran Meshorer and Kathrine Plath. Landes Bioscences and Springer Science, Available from
    • Nakagawa, M., Yamanaka, S. 2010. Reprogramming of somatic cells to pluripotency. In The Cell Biology of Stem Cell. Edited by Eran Meshorer and Kathrine Plath. Landes Bioscences and Springer Science. pp. 215-224. Available from www.springer.com/life+sciences/book/978-1-4419-7036-7.
    • (2010) The Cell Biology of Stem Cell , pp. 215-224
    • Nakagawa, M.1    Yamanaka, S.2
  • 50
    • 68249094138 scopus 로고    scopus 로고
    • Repair of acute myocardial infarction by human stemness factors induced pluripotent stem cells
    • doi:10.1161/CIRCULATIONAHA.109.865154
    • Nelson, T.J., Martinez-Fernandez, A., Yamada, S., Perez-Terzic, C., Ikeda, Y., and Terzic, A. 2009. Repair of acute myocardial infarction by human stemness factors induced pluripotent stem cells. Circulation, 120(5): 408-416. doi:10.1161/CIRCULATIONAHA.109.865154.
    • (2009) Circulation , vol.120 , Issue.5 , pp. 408-416
    • Nelson, T.J.1    Martinez-Fernandez, A.2    Yamada, S.3    Perez-Terzic, C.4    Ikeda, Y.5    Terzic, A.6
  • 51
    • 79953021243 scopus 로고    scopus 로고
    • Development of defective and persistent Sendai virus vector: A unique gene delivery/expression system ideal for cell reprogramming
    • doi:10.1074/jbc.M110.183780
    • Nishimura, K., Sano, M., Ohtaka, M., Furuta, B., Umemura, Y., Nakajima, Y., et al. 2011. Development of defective and persistent Sendai virus vector: a unique gene delivery/expression system ideal for cell reprogramming. J. Biol. Chem. 286(6): 4760-4771. doi:10.1074/jbc.M110.183780.
    • (2011) J. Biol. Chem. , vol.286 , Issue.6 , pp. 4760-4771
    • Nishimura, K.1    Sano, M.2    Ohtaka, M.3    Furuta, B.4    Umemura, Y.5    Nakajima, Y.6
  • 52
    • 77955846452 scopus 로고    scopus 로고
    • Induction of pluripotency by defined factors
    • doi:10.1016/j.yexcr.2010.04.023
    • Okita, K., and Yamanaka, S. 2010. Induction of pluripotency by defined factors. Exp. Cell Res. 316(16): 2565-2570. doi:10.1016/j.yexcr.2010.04.023.
    • (2010) Exp. Cell Res. , vol.316 , Issue.16 , pp. 2565-2570
    • Okita, K.1    Yamanaka, S.2
  • 53
    • 55849117368 scopus 로고    scopus 로고
    • Generation of mouse induced pluripotent stem cells without viral vectors
    • doi:10.1126/science.1164270
    • Okita, K., Nakagawa, M., Hyenjong, H., Ichisaka, T., and Yamanaka, S. 2008. Generation of mouse induced pluripotent stem cells without viral vectors. Science, 322(5903): 949-953. doi:10.1126/science.1164270.
    • (2008) Science , vol.322 , Issue.5903 , pp. 949-953
    • Okita, K.1    Nakagawa, M.2    Hyenjong, H.3    Ichisaka, T.4    Yamanaka, S.5
  • 54
    • 50549089957 scopus 로고    scopus 로고
    • Disease specific induced pluripotent stem cells
    • doi:10.1016/j.cell.2008.07.041.8691744
    • Park, I.H., Arora, N., Huo, H., Maherali, N., Ahfeldt, T., Shimamura, A., et al. 2008. Disease specific induced pluripotent stem cells. Cell, 134(5): 877-886. doi:10.1016/j.cell.2008.07.041.8691744.
    • (2008) Cell , vol.134 , Issue.5 , pp. 877-886
    • Park, I.H.1    Arora, N.2    Huo, H.3    Maherali, N.4    Ahfeldt, T.5    Shimamura, A.6
  • 55
    • 79952846468 scopus 로고    scopus 로고
    • Progress in understanding reprogramming to the induced pluripotent state
    • doi:10.1038/nrg2955
    • Plath, K., and Lowry, W.E. 2011. Progress in understanding reprogramming to the induced pluripotent state. Nat. Rev. Genet. 12(4): 253-265. doi:10.1038/nrg2955.
    • (2011) Nat. Rev. Genet. , vol.12 , Issue.4 , pp. 253-265
    • Plath, K.1    Lowry, W.E.2
  • 56
    • 78651254192 scopus 로고    scopus 로고
    • Activation of pluripotency genes in human fibroblast cells by a novel mRNA based approach
    • doi:10.1371/journal.pone.0014397.21209933
    • Plews, J.R., Li, J., Jones, M., Moore, H.D., Mason, C., Andrews, P.W., and Na, J. 2010. Activation of pluripotency genes in human fibroblast cells by a novel mRNA based approach. PLoS ONE, 5(12): e14397. doi:10.1371/journal.pone.0014397.21209933.
    • (2010) PLoS ONE , vol.5 , Issue.12
    • Plews, J.R.1    Li, J.2    Jones, M.3    Moore, H.D.4    Mason, C.5    Andrews, P.W.6    Na, J.7
  • 57
    • 78650752402 scopus 로고    scopus 로고
    • Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells
    • doi:10.1038/nbt.1667
    • Polo, J.M., Liu, S., Figueroa, M.E., Kulalert, W., Eminli, S., Tan, K.Y., et al. 2010. Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells. Nat. Biotechnol. 28(8): 848-855. doi:10.1038/nbt.1667.
    • (2010) Nat. Biotechnol. , vol.28 , Issue.8 , pp. 848-855
    • Polo, J.M.1    Liu, S.2    Figueroa, M.E.3    Kulalert, W.4    Eminli, S.5    Tan, K.Y.6
  • 58
    • 78650084131 scopus 로고    scopus 로고
    • High-efficient generation of induced pluripotent stem cells from human astrocytes
    • doi:10.1371/journal.pone.0015526
    • Ruiz, S., Brennand, K., Panopoulos, A.D., Herrerías, A., Gage, F.H., and Izpisua-Belmonte, J.C. 2010. High-efficient generation of induced pluripotent stem cells from human astrocytes. PLoS ONE, 5(12): e15526. doi:10.1371/journal.pone.0015526.
    • (2010) PLoS ONE , vol.5 , Issue.12
    • Ruiz, S.1    Brennand, K.2    Panopoulos, A.D.3    Herrerías, A.4    Gage, F.H.5    Izpisua-Belmonte, J.C.6
  • 59
    • 70349622815 scopus 로고    scopus 로고
    • The molecular mechanism of induced pluripotency: A two-stage switch
    • doi:10.1007/s12015-009-9077-x
    • Scheper, W., and Copray, S. 2009. The molecular mechanism of induced pluripotency: a two-stage switch. Stem Cell Rev. 5(3): 204-223. doi:10.1007/s12015-009-9077-x.
    • (2009) Stem Cell Rev , vol.5 , Issue.3 , pp. 204-223
    • Scheper, W.1    Copray, S.2
  • 60
    • 0023128247 scopus 로고
    • Redesigning the body plan of Drosophila by ectopic expression of the homoeotic gene Antennapedia
    • doi:10.1038/325816a0
    • Schneuwly, S., Klemenz, R., and Gehring, W.J. 1987. Redesigning the body plan of Drosophila by ectopic expression of the homoeotic gene Antennapedia. Nature, 325(6107): 816-818. doi:10.1038/325816a0.
    • (1987) Nature , vol.325 , Issue.6107 , pp. 816-818
    • Schneuwly, S.1    Klemenz, R.2    Gehring, W.J.3
  • 61
    • 77955118962 scopus 로고    scopus 로고
    • Generation of human induced pluripotent stem cells by simple transient transfection of plasmid DNA encoding reprogramming factors
    • doi:10.1186/1471-213X-10-81
    • Si-Tayeb, K., Noto, F.K., Sepac, A., Sedlic, F., Bosnjak, Z.J., Lough, J.W., and Duncan, S.A. 2010. Generation of human induced pluripotent stem cells by simple transient transfection of plasmid DNA encoding reprogramming factors. BMC Dev. Biol. 10(1): 81-90. doi:10.1186/1471-213X-10-81.
    • (2010) BMC Dev. Biol. , vol.10 , Issue.1 , pp. 81-90
    • Si-Tayeb, K.1    Noto, F.K.2    Sepac, A.3    Sedlic, F.4    Bosnjak, Z.J.5    Lough, J.W.6    Duncan, S.A.7
  • 62
    • 77952172633 scopus 로고    scopus 로고
    • Dynamic single-cell imaging of direct reprogramming reveals an early specifying event
    • doi:10. 1038/nbt.1632
    • Smith, Z.D., Nachman, I., Regev, A., and Meissner, A. 2010. Dynamic single-cell imaging of direct reprogramming reveals an early specifying event. Nat. Biotechnol. 28(5): 521-526. doi:10. 1038/nbt.1632.
    • (2010) Nat. Biotechnol. , vol.28 , Issue.5 , pp. 521-526
    • Smith, Z.D.1    Nachman, I.2    Regev, A.3    Meissner, A.4
  • 63
    • 39149115929 scopus 로고    scopus 로고
    • Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse
    • doi:10.1016/j.stem.2008.02.001
    • Stadtfeld, M., Maherali, N., Breault, D.T., and Hochedlinger, K. 2008a. Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. Cell Stem Cell, 2(3): 230-240. doi:10.1016/j.stem.2008.02.001.
    • (2008) Cell Stem Cell , vol.2 , Issue.3 , pp. 230-240
    • Stadtfeld, M.1    Maherali, N.2    Breault, D.T.3    Hochedlinger, K.4
  • 64
    • 55849115999 scopus 로고    scopus 로고
    • Induced pluripotent stem cells generated without viral integration
    • doi:10.1126/science. 1162494
    • Stadtfeld, M., Nagaya, M., Utikal, J., Weir, G., and Hochedlinger, K. 2008b. Induced pluripotent stem cells generated without viral integration. Science, 322(5903): 945-949. doi:10.1126/science. 1162494.
    • (2008) Science , vol.322 , Issue.5903 , pp. 945-949
    • Stadtfeld, M.1    Nagaya, M.2    Utikal, J.3    Weir, G.4    Hochedlinger, K.5
  • 65
    • 77957671912 scopus 로고    scopus 로고
    • Reprogramming of human pheripheral blood cells to induced pluripotent stem cells
    • doi:10.1016/j.stem.2010.06.002
    • Staerk, J., Dawlaty, M.M., Gao, Q., Maetzel, D., Hanna, J., Sommer, C.A., et al. 2010. Reprogramming of human pheripheral blood cells to induced pluripotent stem cells. Cell Stem Cell, 7(1): 20-24. doi:10.1016/j.stem.2010.06.002.
    • (2010) Cell Stem Cell , vol.7 , Issue.1 , pp. 20-24
    • Staerk, J.1    Dawlaty, M.M.2    Gao, Q.3    Maetzel, D.4    Hanna, J.5    Sommer, C.A.6
  • 66
    • 79955780736 scopus 로고    scopus 로고
    • Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells
    • doi:10.1038/nbt.1862
    • Subramanyam, D., Lamouille, S., Judson, R.L., Liu, J.Y., Bucay, N., Derynck, R., and Blelloch, R. 2011. Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells. Nat. Biotechnol. 29(5): 443-448. doi:10.1038/nbt.1862.
    • (2011) Nat. Biotechnol. , vol.29 , Issue.5 , pp. 443-448
    • Subramanyam, D.1    Lamouille, S.2    Judson, R.L.3    Liu, J.Y.4    Bucay, N.5    Derynck, R.6    Blelloch, R.7
  • 67
    • 70349446099 scopus 로고    scopus 로고
    • Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells
    • doi:10.1073/pnas.0908450106
    • Sun, N., Panetta, N.J., Gupta, D.M., Wilson, D., Lee, A., Jia, F., et al. 2009. Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells. Proc. Natl. Acad. Sci. U.S.A. 106(37): 15720-15725. doi:10.1073/pnas.0908450106.
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , Issue.37 , pp. 15720-15725
    • Sun, N.1    Panetta, N.J.2    Gupta, D.M.3    Wilson, D.4    Lee, A.5    Jia, F.6
  • 68
    • 0035797898 scopus 로고    scopus 로고
    • Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells
    • doi:10.1016/S0960-9822(01)00459-6
    • Tada, M., Takahama, Y., Abe, K., Nakatsuji, N., and Tada, T. 2001. Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells. Curr. Biol. 11(19): 1553-1558. doi:10.1016/S0960-9822(01)00459-6.
    • (2001) Curr. Biol. , vol.11 , Issue.19 , pp. 1553-1558
    • Tada, M.1    Takahama, Y.2    Abe, K.3    Nakatsuji, N.4    Tada, T.5
  • 69
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • doi:10.1016/j.cell.2006.07.024
    • Takahashi, K., and Yamanaka, S. 2006. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell, 126(4): 663-676. doi:10.1016/j.cell.2006.07.024.
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 70
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • doi:10.1016/j.cell.2007.11.019
    • Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., and Yamanaka, S. 2007. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell, 131(5): 861-872. doi:10.1016/j.cell.2007.11.019.
    • (2007) Cell , vol.131 , Issue.5 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 71
    • 69349098273 scopus 로고    scopus 로고
    • Immortalization eliminates a roadblock during cellular reprogramming into iPS cells
    • doi:10.1038/nature08285
    • Utikal, J., Polo, J.M., Stadtfeld, M., Maherali, N., Kulalert, W., Walsh, R.M., et al. 2009. Immortalization eliminates a roadblock during cellular reprogramming into iPS cells. Nature, 460(7259): 1145-1148. doi:10.1038/nature08285.
    • (2009) Nature , vol.460 , Issue.7259 , pp. 1145-1148
    • Utikal, J.1    Polo, J.M.2    Stadtfeld, M.3    Maherali, N.4    Kulalert, W.5    Walsh, R.M.6
  • 72
    • 0032560827 scopus 로고    scopus 로고
    • Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei
    • doi:10.1038/28615
    • Wakayama, T., Perry, A.C., Zuccotti, M., Johnson, K.R., and Yanagimachi, R. 1998. Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei. Nature, 394 (6691): 369-374. doi:10.1038/28615.
    • (1998) Nature , vol.394 , Issue.6691 , pp. 369-374
    • Wakayama, T.1    Perry, A.C.2    Zuccotti, M.3    Johnson, K.R.4    Yanagimachi, R.5
  • 73
    • 48249130858 scopus 로고    scopus 로고
    • Chromosomal transposition of PiggyBac in mouse embryonic stem cells
    • doi:10.1073/pnas.0801017105
    • Wang, W., Lin, C., Lu, D., Ning, Z., Cox, T., Melvin, D., et al. 2008. Chromosomal transposition of PiggyBac in mouse embryonic stem cells. Proc. Natl. Acad. Sci. U.S.A. 105(27): 9290-9295. doi:10.1073/pnas.0801017105.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , Issue.27 , pp. 9290-9295
    • Wang, W.1    Lin, C.2    Lu, D.3    Ning, Z.4    Cox, T.5    Melvin, D.6
  • 74
    • 77958536106 scopus 로고    scopus 로고
    • Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA
    • doi:10.1016/j.stem.2010.08.012
    • Warren, L., Manos, P.D., Ahfeldt, T., Loh, Y.H., Li, H., Lau, F., et al. 2010. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell, 7(5): 618-630. doi:10.1016/j.stem.2010.08.012.
    • (2010) Cell Stem Cell , vol.7 , Issue.5 , pp. 618-630
    • Warren, L.1    Manos, P.D.2    Ahfeldt, T.3    Loh, Y.H.4    Li, H.5    Lau, F.6
  • 75
    • 49449096588 scopus 로고    scopus 로고
    • A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types
    • doi:10.1038/nbt1483
    • Wernig, M., Lengner, C.J., Hanna, J., Lodato, M.A., Steine, E., Foreman, R., et al. 2008a. A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types. Nat. Biotechnol. 26(8): 916-924. doi:10.1038/nbt1483.
    • (2008) Nat. Biotechnol. , vol.26 , Issue.8 , pp. 916-924
    • Wernig, M.1    Lengner, C.J.2    Hanna, J.3    Lodato, M.A.4    Steine, E.5    Foreman, R.6
  • 76
    • 42649130264 scopus 로고    scopus 로고
    • Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease
    • doi:10.1073/pnas.0801677105
    • Wernig, M., Zhao, J.P., Pruszak, J., Hedlund, E., Fu, D., Soldner, F., et al. 2008b. Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proc. Natl. Acad. Sci. U.S.A. 105 (15): 5856-5861. doi:10.1073/pnas.0801677105.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , Issue.15 , pp. 5856-5861
    • Wernig, M.1    Zhao, J.P.2    Pruszak, J.3    Hedlund, E.4    Fu, D.5    Soldner, F.6
  • 77
    • 0031044215 scopus 로고    scopus 로고
    • Viable offspring derived from fetal and adult mammalian cells
    • doi:10.1038/385810a0
    • Wilmut, I., Schnieke, A.E., McWhir, J., Kind, A.J., and Campbell, K.H. 1997. Viable offspring derived from fetal and adult mammalian cells. Nature, 385(6619): 810-813. doi:10.1038/385810a0.
    • (1997) Nature , vol.385 , Issue.6619 , pp. 810-813
    • Wilmut, I.1    Schnieke, A.E.2    McWhir, J.3    Kind, A.J.4    Campbell, K.H.5
  • 78
    • 64749083939 scopus 로고    scopus 로고
    • piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
    • doi:10.1038/nature07863
    • Woltjen, K., Michael, I.P., Mohseni, P., Desai, R., Mileikovsky, M., Hämäläinen, R., et al. 2009. piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature, 458(7239): 766-770. doi:10.1038/nature07863.
    • (2009) Nature , vol.458 , Issue.7239 , pp. 766-770
    • Woltjen, K.1    Michael, I.P.2    Mohseni, P.3    Desai, R.4    Mileikovsky, M.5    Hämäläinen, R.6
  • 79
    • 2542455620 scopus 로고    scopus 로고
    • Reprogramming of B cells into macrophages
    • doi:10.1016/S0092-8674(04)00419-2
    • Xie, H., Ye, M., Feng, R., and Graf, T. 2004. Reprogramming of B cells into macrophages. Cell, 117(5): 663-676. doi:10.1016/S0092-8674(04)00419-2.
    • (2004) Cell , vol.117 , Issue.5 , pp. 663-676
    • Xie, H.1    Ye, M.2    Feng, R.3    Graf, T.4
  • 80
    • 58849113643 scopus 로고    scopus 로고
    • Phenotypic correction of murine hemophilia A using an iPS cell-based therapy
    • doi:10.1073/pnas.0812090106
    • Xu, D., Alipio, Z., Fink, L.M., Adcock, D.M., Yang, J., Ward, D.C., and Ma, Y. 2009. Phenotypic correction of murine hemophilia A using an iPS cell-based therapy. Proc. Natl. Acad. Sci. U.S.A. 106 (3): 808-813. doi:10.1073/pnas.0812090106.
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , Issue.3 , pp. 808-813
    • Xu, D.1    Alipio, Z.2    Fink, L.M.3    Adcock, D.M.4    Yang, J.5    Ward, D.C.6    Ma, Y.7
  • 81
    • 65649116572 scopus 로고    scopus 로고
    • Human induced pluripotent stem cells free of vector and transgene sequences
    • doi:10.1126/science.1172482
    • Yu, J., Hu, K., Smuga-Otto, K., Tian, S., Stewart, R., Slukvin, I.I., and Thomson, J.A. 2009. Human induced pluripotent stem cells free of vector and transgene sequences. Science, 324(5928): 797-801. doi:10.1126/science.1172482.
    • (2009) Science , vol.324 , Issue.5928 , pp. 797-801
    • Yu, J.1    Hu, K.2    Smuga-Otto, K.3    Tian, S.4    Stewart, R.5    Slukvin, I.I.6    Thomson, J.A.7
  • 82
    • 72849137462 scopus 로고    scopus 로고
    • Reprogram human fibroblasts to induced pluripotent stem cells
    • doi:10.1002/stem.201
    • Zhou, W., and Freed, C.R. 2009. Reprogram human fibroblasts to induced pluripotent stem cells. Stem Cells, 27(11): 2667-2674. doi:10.1002/stem.201.
    • (2009) Stem Cells , vol.27 , Issue.11 , pp. 2667-2674
    • Zhou, W.1    Freed, C.R.2
  • 83
    • 66049135249 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells using recombinant proteins
    • doi:10.1016/j.stem.2009.04.005
    • Zhou, H., Wu, S., Joo, J.Y., Zhu, S., Han, D.W., Lin, T., et al. 2009. Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell, 4(5): 381-384. doi:10.1016/j.stem.2009.04.005.
    • (2009) Cell Stem Cell , vol.4 , Issue.5 , pp. 381-384
    • Zhou, H.1    Wu, S.2    Joo, J.Y.3    Zhu, S.4    Han, D.W.5    Lin, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.