Structural dynamics associated with intermediate formation in an archetypal conformational disease

Structure

Volumn 20, Issue 3, 2012, Pages 504-512

  Nyon, Mun Peak ^a   Segu, Lakshmi ^a   Cabrita, Lisa D ^a,b   Lévy, Géraldine R ^a,b   Kirkpatrick, John ^b   Roussel, Benoit D ^c   Patschull, Anathe O M ^a,b   Barrett, Tracey E ^a   Ekeowa, Ugo I ^c   Kerr, Richard ^b   Waudby, Christopher A ^a,b   Kalsheker, Noor ^d   Hill, Marian ^d   Thalassinos, Konstantinos ^a,b   Lomas, David A ^c   Christodoulou, John ^a,b   Gooptu, Bibek ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d QUEEN S MEDICAL CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; EPITOPE; POLYMER;

ALPHA 1 ANTITRYPSIN DEFICIENCY; ARTICLE; CONFORMATIONAL DISEASE; CONFORMATIONAL TRANSITION; IN VIVO STUDY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEFECT; PROTEIN POLYMERIZATION; TEMPERATURE;

ALPHA 1-ANTITRYPSIN; EPITOPES; HUMANS; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; POLYMERIZATION; PROTEIN CONFORMATION; PROTEOSTASIS DEFICIENCIES;

EID: 84857926856     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2012.01.012     Document Type: Article

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