Mitochondrial permeability transition pore opening induces the initial process of renal calcium crystallization

Free Radical Biology and Medicine

Volumn 52, Issue 7, 2012, Pages 1207-1217

  Niimi, Kazuhiro ^a   Yasui, Takahiro ^a   Hirose, Masahito ^b   Hamamoto, Shuzo ^a   Itoh, Yasunori ^c   Okada, Atsushi ^a   Kubota, Yasue ^a   Kojima, Yoshiyuki ^a   Tozawa, Keiichi ^a   Sasaki, Shoichi ^a   Hayashi, Yutaro ^a   Kohri, Kenjiro ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^b Kainan Hospital   (Japan)

^c Nagoya City University West Medical Center   (Japan)

Author keywords

Cyclosporine A; Free radicals; Mitochondrial permeability transition pore; Oxidative stress; Renal calcium crystallization; Renal tubular cell injury

Indexed keywords

4 HYDROXYNONENAL; 8 HYDROXYDEOXYGUANOSINE; CALCIUM; CASPASE 3; COPPER ZINC SUPEROXIDE DISMUTASE; CYCLOSPORIN A; CYTOCHROME C; ETHYLENE GLYCOL; MALONALDEHYDE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; WHEWELLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; CRYSTALLIZATION; IMMUNOHISTOCHEMISTRY; KIDNEY CALCIFICATION; KIDNEY TUBULE CELL; MALE; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; NEPHROLITHIASIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RENAL CALCIUM CRYSTALLIZATION; ULTRASTRUCTURE; URINALYSIS;

ANIMALS; BLOTTING, WESTERN; CALCIUM; CALCIUM OXALATE; CELLS, CULTURED; CRYSTALLIZATION; CYCLOSPORINE; IMMUNOENZYME TECHNIQUES; IMMUNOSUPPRESSIVE AGENTS; KIDNEY; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 84857911907     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.01.005     Document Type: Article

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