Mitochondrial dysfunction is a primary event in renal cell oxalate toxicity

Kidney International

Volumn 66, Issue 5, 2004, Pages 1890-1900

  Cao, Lu Cheng ^a   Honeyman, Thomas W ^a   Cooney, Rachel ^a   Kennington, Lori ^a   Scheid, Cheryl R ^a   Jonassen, Julie A ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Arachidonic acid; Kidney epithelial cells; Lysophosphatidyl choline; Mitochondrial membrane potential; Oxalate; Phospholipase A2; Reactive oxygen species

Indexed keywords

ARACHIDONIC ACID; ARACHIDONYL TRIFLUOROMETHYL KETONE; BENZENE DERIVATIVE; CASPASE; CERAMIDE; DYE; LIPID; LIPID PEROXIDE; LYSOPHOSPHATIDYLCERAMIDE; OXALIC ACID; PHOSPHOLIPASE A2 INHIBITOR; PHOSPHOLIPID; PROTEIN; SERINE PROTEINASE; THIOL GROUP; UNCLASSIFIED DRUG; ARACHIDONIC ACID DERIVATIVE; ARACHIDONYLTRIFLUOROMETHANE; DRUG DERIVATIVE; ENZYME INHIBITOR; LYSOPHOSPHATIDYLCHOLINE; N ACETYLSPHINGOSINE; N-ACETYLSPHINGOSINE; OXALIC ACID DERIVATIVE; PHOSPHOLIPASE A; REACTIVE OXYGEN METABOLITE; SPHINGOSINE; WE 201;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CELL STRAIN; CONTROLLED STUDY; ENZYME ACTIVATION; LIPID PEROXIDATION; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; MOLECULE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; REACTION TIME; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; CELL MEMBRANE POTENTIAL; DOG; DRUG ANTAGONISM; DRUG EFFECT; INTRACELLULAR MEMBRANE; KIDNEY; METABOLISM; PATHOPHYSIOLOGY;

ANIMALS; ARACHIDONIC ACID; ARACHIDONIC ACIDS; CASPASES; CELL LINE; DOGS; ENZYME ACTIVATION; ENZYME INHIBITORS; INTRACELLULAR MEMBRANES; KIDNEY; LIPID PEROXIDATION; LYSOPHOSPHATIDYLCHOLINES; MEMBRANE POTENTIALS; MITOCHONDRIA; OXALATES; PHOSPHOLIPASES A; REACTIVE OXYGEN SPECIES; SPHINGOSINE;

EID: 14644391026     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1523-1755.2004.00963.x     Document Type: Article

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