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Volumn 12, Issue 1, 2012, Pages 28-37

Healing of rat femoral segmental defect with bone morphogenetic protein-2: A dose response study

Author keywords

Critical size defect; Fracture; Growth factors

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; COLLAGEN SPONGE; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2;

EID: 84857818533     PISSN: 11087161     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (36)

References (62)
  • 6
    • 0034786965 scopus 로고    scopus 로고
    • Mosaicplasty for the Treatment of Articular Defects of the Knee and Ankle
    • Hangody L, Feczko P, Bartha L, Bodo G, Kish G. Mosaicplasty for the Treatment of Articular Defects of the Knee and Ankle. Clin Orthop Relat Res 2001;(391Suppl):S328-S336.
    • (2001) Clin Orthop Relat Res , Issue.391 SUPPL.
    • Hangody, L.1    Feczko, P.2    Bartha, L.3    Bodo, G.4    Kish, G.5
  • 7
    • 0037272730 scopus 로고    scopus 로고
    • The Validity of Clinical Examination in the Diagnosis of Loosening of Components in Total Hip Arthroplasty
    • Roder C, Eggli S, Aebi M, Busato A. The Validity of Clinical Examination in the Diagnosis of Loosening of Components in Total Hip Arthroplasty. J Bone Joint Surg Br 2003;85(1):37-44.
    • (2003) J Bone Joint Surg Br , vol.85 , Issue.1 , pp. 37-44
    • Roder, C.1    Eggli, S.2    Aebi, M.3    Busato, A.4
  • 8
    • 0042626183 scopus 로고    scopus 로고
    • Clinical Applications of Recombinant Human BMPs: Early Experience and Future Development
    • Einhorn TA. Clinical Applications of Recombinant Human BMPs: Early Experience and Future Development. J Bone Joint Surg Am 2003;85-A Suppl 3:82-8.
    • (2003) J Bone Joint Surg Am , vol.85 A , Issue.SUPPL. 3 , pp. 82-88
    • Einhorn, T.A.1
  • 9
    • 0036599845 scopus 로고    scopus 로고
    • The Role of Growth Factors in the Repair of Bone. Biology and Clinical Applications
    • Lieberman JR, Daluiski A, Einhorn TA. The Role of Growth Factors in the Repair of Bone. Biology and Clinical Applications. J Bone Joint Surg Am 2002;84-A(6):1032-44.
    • (2002) J Bone Joint Surg Am , vol.84 A , Issue.6 , pp. 1032-1044
    • Lieberman, J.R.1    Daluiski, A.2    Einhorn, T.A.3
  • 10
    • 0027753913 scopus 로고
    • Expression of Four Growth Factors During Fracture Repair
    • Bourque WT, Gross M, Hall BK. Expression of Four Growth Factors During Fracture Repair. Int J Dev Biol 1993;37(4):573-9.
    • (1993) Int J Dev Biol , vol.37 , Issue.4 , pp. 573-579
    • Bourque, W.T.1    Gross, M.2    Hall, B.K.3
  • 11
    • 0029143554 scopus 로고
    • Platelet-Derived Growth Factor Expression in Normally Healing Human Fractures
    • Andrew JG, Hoyland JA, Freemont AJ, Marsh DR. Platelet-Derived Growth Factor Expression in Normally Healing Human Fractures. Bone 1995;16(4):455-60.
    • (1995) Bone , vol.16 , Issue.4 , pp. 455-460
    • Andrew, J.G.1    Hoyland, J.A.2    Freemont, A.J.3    Marsh, D.R.4
  • 12
    • 0031733871 scopus 로고    scopus 로고
    • Expression of Bone Morphogenetic Proteins in Fracture Healing
    • Bostrom MP. Expression of Bone Morphogenetic Proteins in Fracture Healing. Clin Orthop Relat Res 1998; (355 Suppl):S116-S123.
    • (1998) Clin Orthop Relat Res , Issue.355 SUPPL.
    • Bostrom, M.P.1
  • 13
    • 0035034516 scopus 로고    scopus 로고
    • Local Application of Growth Factors (Insulin-Like Growth Factor-1 and Transforming Growth Factor-Beta1) From a Biodegradable Poly(D,L-Lactide) Coating of Osteosynthetic Implants Accelerates Fracture Healing in Rats
    • Schmidmaier G, Wildemann B, Bail H, Lucke M, Fuchs T, Stemberger A, Flyvbjerg A, Haas NP, Raschke M. Local Application of Growth Factors (Insulin-Like Growth Factor-1 and Transforming Growth Factor-Beta1) From a Biodegradable Poly(D,L-Lactide) Coating of Osteosynthetic Implants Accelerates Fracture Healing in Rats. Bone 2001;28(4):341-50.
    • (2001) Bone , vol.28 , Issue.4 , pp. 341-350
    • Schmidmaier, G.1    Wildemann, B.2    Bail, H.3    Lucke, M.4    Fuchs, T.5    Stemberger, A.6    Flyvbjerg, A.7    Haas, N.P.8    Raschke, M.9
  • 14
    • 38049090640 scopus 로고    scopus 로고
    • Accelerated Fracture Healing in the Geriatric, Osteoporotic Rat With Recombinant Human Platelet-Derived Growth Factor-BB and an Injectable Beta-Tricalcium Phosphate/Collagen Matrix
    • Hollinger JO, Onikepe AO, MacKrell J, Einhorn T, Bradica G, Lynch S, Hart CE. Accelerated Fracture Healing in the Geriatric, Osteoporotic Rat With Recombinant Human Platelet-Derived Growth Factor-BB and an Injectable Beta-Tricalcium Phosphate/Collagen Matrix. J Orthop Res 2008;26(1):83-90.
    • (2008) J Orthop Res , vol.26 , Issue.1 , pp. 83-90
    • Hollinger, J.O.1    Onikepe, A.O.2    Mackrell, J.3    Einhorn, T.4    Bradica, G.5    Lynch, S.6    Hart, C.E.7
  • 15
    • 0031974284 scopus 로고    scopus 로고
    • Bone Morphogenetic Protein and Bone Morphogenetic Protein Gene Family in Bone Formation and Repair
    • Wozney JM, Rosen V. Bone Morphogenetic Protein and Bone Morphogenetic Protein Gene Family in Bone Formation and Repair. Clin Orthop Relat Res 1998;(346):26-37.
    • (1998) Clin Orthop Relat Res , Issue.346 , pp. 26-37
    • Wozney, J.M.1    Rosen, V.2
  • 16
    • 0032101214 scopus 로고    scopus 로고
    • Bone Morphogenetic Proteins: From Basic Studies to Clinical Approaches
    • Sakou T. Bone Morphogenetic Proteins: From Basic Studies to Clinical Approaches. Bone 1998;22(6):591-603.
    • (1998) Bone , vol.22 , Issue.6 , pp. 591-603
    • Sakou, T.1
  • 17
    • 34250019537 scopus 로고
    • Bone: Formation by Autoinduction
    • Urist, M. R. Bone: Formation by Autoinduction. Science 1965;150:893-9.
    • (1965) Science , vol.150 , pp. 893-899
    • Urist M., R.1
  • 18
    • 0029737070 scopus 로고    scopus 로고
    • Bone Morphogenetric Proteins: Multifunctional Regulators of Vertebrate Development
    • Hogan, R. L. M. Bone Morphogenetric Proteins: Multifunctional Regulators of Vertebrate Development. Genes & Development 1998;1580-94.
    • (1998) Genes & Development , pp. 1580-1594
    • Hogan, R.L.M.1
  • 20
    • 0027185702 scopus 로고
    • Bone Morphogenetic Protein-2 Causes Commitment and Differentiation in C3H10T1/2 and 3T3 Cells
    • Wang EA, Israel DI, Kelly S, Luxenberg DP. Bone Morphogenetic Protein-2 Causes Commitment and Differentiation in C3H10T1/2 and 3T3 Cells. Growth Factors 1993;9(1):57-71.
    • (1993) Growth Factors , vol.9 , Issue.1 , pp. 57-71
    • Wang, E.A.1    Israel, D.I.2    Kelly, S.3    Luxenberg, D.P.4
  • 22
    • 0025857671 scopus 로고
    • Recombinant Human Bone Morphogenetic Protein-2 Stimulates Osteoblastic Maturation and Inhibits Myogenic Differentiation in Vitro
    • Yamaguchi A, Katagiri T, Ikeda T, Wozney JM, Rosen V, Wang EA, Kahn AJ, Suda T, Yoshiki S. Recombinant Human Bone Morphogenetic Protein-2 Stimulates Osteoblastic Maturation and Inhibits Myogenic Differentiation in Vitro. J Cell Biol 1991;113(3):681-7.
    • (1991) J Cell Biol , vol.113 , Issue.3 , pp. 681-687
    • Yamaguchi, A.1    Katagiri, T.2    Ikeda, T.3    Wozney, J.M.4    Rosen, V.5    Wang, E.A.6    Kahn, A.J.7    Suda, T.8    Yoshiki, S.9
  • 25
    • 0026757708 scopus 로고
    • The Healing of Segmental Bone Defects, Induced by Recombinant Human Bone Morphogenetic Protein (rhBMP-2). A Radiographic, Histological, and Biomechanical Study in Rats
    • Yasko AW, Lane JM, Fellinger EJ, Rosen V, Wozney JM, Wang EA. The Healing of Segmental Bone Defects, Induced by Recombinant Human Bone Morphogenetic Protein (rhBMP-2). A Radiographic, Histological, and Biomechanical Study in Rats. Journal of Bone and Joint Surgery 1992;74-A:659-70.
    • (1992) Journal of Bone and Joint Surgery , vol.74 A , pp. 659-670
    • Yasko, A.W.1    Lane, J.M.2    Fellinger, E.J.3    Rosen, V.4    Wozney, J.M.5    Wang, E.A.6
  • 26
    • 0033080550 scopus 로고    scopus 로고
    • Healing of Segmental Bone Defects in Rats Induced by a Beta- TCP-MCPM Cement Combined With rhBMP-2
    • Ohura K, Hamanishi C, Tanaka S, Matsuda N. Healing of Segmental Bone Defects in Rats Induced by a Beta- TCP-MCPM Cement Combined With rhBMP-2. J Biomed Mater Res 1999;44(2):168-75.
    • (1999) J Biomed Mater Res , vol.44 , Issue.2 , pp. 168-175
    • Ohura, K.1    Hamanishi, C.2    Tanaka, S.3    Matsuda, N.4
  • 27
    • 66149097475 scopus 로고    scopus 로고
    • RhBMP-2 Enhances the Bone Healing Response in a Diabetic Rat Segmental Defect Model
    • Azad V, Breitbart E, Al Zube L, Yeh S, O'Connor JP, Lin SS. rhBMP-2 Enhances the Bone Healing Response in a Diabetic Rat Segmental Defect Model. J Orthop Trauma 2009;23(4):267-76.
    • (2009) J Orthop Trauma , vol.23 , Issue.4 , pp. 267-276
    • Azad, V.1    Breitbart, E.2    Al Zube, L.3    Yeh, S.4    O'Connor, J.P.5    Lin, S.S.6
  • 28
    • 0029569034 scopus 로고
    • Evaluation of rhBMP-2 With an OPLA Carrier in a Canine Posterolateral (Transverse Process) Spinal Fusion Model
    • Sandhu HS, Kanim LE, Kabo JM, Toth JM, Zeegan EN, Liu D, Seeger LL, Dawson EG. Evaluation of rhBMP-2 With an OPLA Carrier in a Canine Posterolateral (Transverse Process) Spinal Fusion Model. Spine 1995; 20(24):2669-82.
    • (1995) Spine , vol.20 , Issue.24 , pp. 2669-2682
    • Sandhu, H.S.1    Kanim, L.E.2    Kabo, J.M.3    Toth, J.M.4    Zeegan, E.N.5    Liu, D.6    Seeger, L.L.7    Dawson, E.G.8
  • 31
    • 0036894554 scopus 로고    scopus 로고
    • Use of Recombinant Human Bone Morphogenetic Protein-2 to Achieve Posterolateral Lumbar Spine Fusion in Humans: A Prospective, Randomized Clinical Pilot Trial: 2002 Volvo Award in Clinical Studies
    • Boden SD, Kang J, Sandhu H, Heller JG. Use of Recombinant Human Bone Morphogenetic Protein-2 to Achieve Posterolateral Lumbar Spine Fusion in Humans: a Prospective, Randomized Clinical Pilot Trial: 2002 Volvo Award in Clinical Studies. Spine 2002;27(23):2662-73.
    • (2002) Spine , vol.27 , Issue.23 , pp. 2662-2673
    • Boden, S.D.1    Kang, J.2    Sandhu, H.3    Heller, J.G.4
  • 34
    • 35348887265 scopus 로고    scopus 로고
    • Complications of Anterior Cervical Discectomy and Fusion Using Recombinant Human Bone Morphogenetic Protein-2
    • Vaidya R, Carp J, Sethi A, Bartol S, Craig J, Les CM. Complications of Anterior Cervical Discectomy and Fusion Using Recombinant Human Bone Morphogenetic Protein-2. Eur Spine J 2007;16(8):1257-65.
    • (2007) Eur Spine J , vol.16 , Issue.8 , pp. 1257-1265
    • Vaidya, R.1    Carp, J.2    Sethi, A.3    Bartol, S.4    Craig, J.5    Les, C.M.6
  • 35
    • 33645508135 scopus 로고    scopus 로고
    • Adverse Effects Associated With High-Dose Recombinant Human Bone Morphogenetic Protein-2 Use in Anterior Cervical Spine Fusion
    • Shields LB, Raque GH, Glassman SD, Campbell M, Vitaz T, Harpring J, Shields CB. Adverse Effects Associated With High-Dose Recombinant Human Bone Morphogenetic Protein-2 Use in Anterior Cervical Spine Fusion. Spine (Phila Pa 1976) 2006;31(5):542-7.
    • (2006) Spine (Phila Pa 1976) , vol.31 , Issue.5 , pp. 542-547
    • Shields, L.B.1    Raque, G.H.2    Glassman, S.D.3    Campbell, M.4    Vitaz, T.5    Harpring, J.6    Shields, C.B.7
  • 37
    • 70349208515 scopus 로고    scopus 로고
    • Ultrasound Enhances Recombinant Human BMP-2 Induced Ectopic Bone Formation in a Rat Model
    • 7-24
    • Wijdicks CA, Virdi AS, Sena K, Sumner DR, Leven RM. Ultrasound Enhances Recombinant Human BMP-2 Induced Ectopic Bone Formation in a Rat Model. Ultrasound Med Biol 7-24-2009;35(10):1629-37.
    • (2009) Ultrasound Med Biol , vol.35 , Issue.10 , pp. 1629-1637
    • Wijdicks, C.A.1    Virdi, A.S.2    Sena, K.3    Sumner, D.R.4    Leven, R.M.5
  • 38
    • 70449533085 scopus 로고    scopus 로고
    • Can rhBMP-2 Containing Collagen Sponges Enhance Bone Repair in Ovariectomized Rats?: A Preliminary Study
    • Sarban S, Senkoylu A, Isikan UE, Korkusuz P, Korkusuz F. Can rhBMP-2 Containing Collagen Sponges Enhance Bone Repair in Ovariectomized Rats?: a Preliminary Study. Clin Orthop Relat Res 2009;467(12):3113-20.
    • (2009) Clin Orthop Relat Res , vol.467 , Issue.12 , pp. 3113-3120
    • Sarban, S.1    Senkoylu, A.2    Isikan, U.E.3    Korkusuz, P.4    Korkusuz, F.5
  • 39
    • 75749153662 scopus 로고    scopus 로고
    • Effect of Recombinant Human Transforming Growth Factor-Beta2 Dose on Bone Formation in Rat Femur Titanium Implant Model
    • Sena K, Sumner DR, Virdi AS. Effect of Recombinant Human Transforming Growth Factor-Beta2 Dose on Bone Formation in Rat Femur Titanium Implant Model. J Biomed Mater Res A 2010;92(3):1210-7.
    • (2010) J Biomed Mater Res A , vol.92 , Issue.3 , pp. 1210-1217
    • Sena, K.1    Sumner, D.R.2    Virdi, A.S.3
  • 40
    • 23944464984 scopus 로고    scopus 로고
    • Depressed Bone Mineralization Following High Dose TGFBeta1 Application in an Orthopedic Implant Model
    • Broderick E, Infanger S, Turner TM, Sumner DR. Depressed Bone Mineralization Following High Dose TGFBeta1 Application in an Orthopedic Implant Model. Calcified Tissue International 2005;76(5):379-84.
    • (2005) Calcified Tissue International , vol.76 , Issue.5 , pp. 379-384
    • Broderick, E.1    Infanger, S.2    Turner, T.M.3    Sumner, D.R.4
  • 41
    • 70350761790 scopus 로고    scopus 로고
    • Canine Investigation of rhBMP-2, Autogenous Bone Graft, and rhBMP-2 With Autogenous Bone Graft for the Healing of a Large Segmental Tibial Defect
    • Boyce AS, Reveal G, Scheid DK, Kaehr DM, Maar D, Watts M, Stone MB. Canine Investigation of rhBMP-2, Autogenous Bone Graft, and rhBMP-2 With Autogenous Bone Graft for the Healing of a Large Segmental Tibial Defect. J Orthop Trauma 2009;23(10):685-92.
    • (2009) J Orthop Trauma , vol.23 , Issue.10 , pp. 685-692
    • Boyce, A.S.1    Reveal, G.2    Scheid, D.K.3    Kaehr, D.M.4    Maar, D.5    Watts, M.6    Stone, M.B.7
  • 42
    • 56149088300 scopus 로고    scopus 로고
    • Improved Healing Efficacy in Canine Ulnar Segmental Defects With Increasing Recombinant Human Bone Morphogenetic Protein-2/Allograft Ratios
    • Jones CB, Sabatino CT, Badura JM, Sietsema DL, Marotta JS. Improved Healing Efficacy in Canine Ulnar Segmental Defects With Increasing Recombinant Human Bone Morphogenetic Protein-2/Allograft Ratios. J Orthop Trauma 2008;22(8):550-9.
    • (2008) J Orthop Trauma , vol.22 , Issue.8 , pp. 550-559
    • Jones, C.B.1    Sabatino, C.T.2    Badura, J.M.3    Sietsema, D.L.4    Marotta, J.S.5
  • 43
    • 0034026950 scopus 로고    scopus 로고
    • Evaluation of Recombinant Human Bone Morphogenetic Protein-2 As a Bone-Graft Substitute in a Canine Segmental Defect Model
    • Sciadini MF, Johnson KD. Evaluation of Recombinant Human Bone Morphogenetic Protein-2 As a Bone-Graft Substitute in a Canine Segmental Defect Model. J Orthop Res 2000;18(2):289-302.
    • (2000) J Orthop Res , vol.18 , Issue.2 , pp. 289-302
    • Sciadini, M.F.1    Johnson, K.D.2
  • 44
    • 0002071012 scopus 로고    scopus 로고
    • Bone Morphogenetic Proteins: From Basic Science to Clinical Applications
    • Suppl 1
    • Reddi AH. Bone Morphogenetic Proteins: From Basic Science to Clinical Applications. J Bone Joint Surg Am 2001;83-A Suppl 1(Pt 1):S1-S6.
    • (2001) J Bone Joint Surg Am , vol.83 A , Issue.PART 1
    • Reddi, A.H.1
  • 45
    • 0242659880 scopus 로고    scopus 로고
    • Collagen Sponges for Bone Regeneration With rhBMP-2
    • Geiger M, Li RH, Friess W. Collagen Sponges for Bone Regeneration With rhBMP-2. Adv Drug Deliv Rev 2003; 55(12):1613-29.
    • (2003) Adv Drug Deliv Rev , vol.55 , Issue.12 , pp. 1613-1629
    • Geiger, M.1    Li, R.H.2    Friess, W.3
  • 46
    • 0014590710 scopus 로고
    • The Relationship Between the Stiffness and the Mineral Content of Bone
    • Currey JD. The Relationship Between the Stiffness and the Mineral Content of Bone. J Biomech 1969;2(4):477-80.
    • (1969) J Biomech , vol.2 , Issue.4 , pp. 477-480
    • Currey, J.D.1
  • 47
    • 0036309121 scopus 로고    scopus 로고
    • The Contribution of the Organic Matrix to Bone's Material Properties
    • Burr DB. The Contribution of the Organic Matrix to Bone's Material Properties. Bone 2002;31(1):8-11.
    • (2002) Bone , vol.31 , Issue.1 , pp. 8-11
    • Burr, D.B.1
  • 48
  • 50
    • 79955057396 scopus 로고    scopus 로고
    • Osteolysis in Transforaminal Lumbar Interbody Fusion With Bone Morphogenetic Protein-2
    • Knox JB, Dai JM III, Orchowski J. Osteolysis in Transforaminal Lumbar Interbody Fusion With Bone Morphogenetic Protein-2. Spine (Phila Pa 1976) 2011;36(8):672-6.
    • (2011) Spine (Phila Pa 1976) , vol.36 , Issue.8 , pp. 672-676
    • Knox, J.B.1    Dai III, J.M.2    Orchowski, J.3
  • 52
    • 65549116404 scopus 로고    scopus 로고
    • Short-Term Osteoclastic Activity Induced by Locally High Concentrations of Recombinant Human Bone Morphogenetic Protein-2 in a Cancellous Bone Environment
    • Toth JM, Boden SD, Burkus JK, Badura JM, Peckham SM, McKay WF. Short-Term Osteoclastic Activity Induced by Locally High Concentrations of Recombinant Human Bone Morphogenetic Protein-2 in a Cancellous Bone Environment. Spine (Phila Pa 1976) 2009;34(6):539-50.
    • (2009) Spine (Phila Pa 1976) , vol.34 , Issue.6 , pp. 539-550
    • Toth, J.M.1    Boden, S.D.2    Burkus, J.K.3    Badura, J.M.4    Peckham, S.M.5    McKay, W.F.6
  • 53
    • 0036694723 scopus 로고    scopus 로고
    • The Effect of Fibroblast Growth Factor-2 on the Osteoinductive Activity of Recombinant Human Bone Morphogenetic Protein-2 in Rat Muscle
    • Fujimura K, Bessho K, Okubo Y, Kusumoto K, Segami N, Iizuka T. The Effect of Fibroblast Growth Factor-2 on the Osteoinductive Activity of Recombinant Human Bone Morphogenetic Protein-2 in Rat Muscle. Arch Oral Biol 2002;47(8):577-84.
    • (2002) Arch Oral Biol , vol.47 , Issue.8 , pp. 577-584
    • Fujimura, K.1    Bessho, K.2    Okubo, Y.3    Kusumoto, K.4    Segami, N.5    Iizuka, T.6
  • 54
    • 0033962370 scopus 로고    scopus 로고
    • Effects of Recombinant Human Fibroblast Growth Factor-2 on Osteogenic Cell Populations During Orthopic Osteogenesis in Vivo
    • Zellin G, Linde A. Effects of Recombinant Human Fibroblast Growth Factor-2 on Osteogenic Cell Populations During Orthopic Osteogenesis in Vivo. Bone 2000;26(2):161-8.
    • (2000) Bone , vol.26 , Issue.2 , pp. 161-168
    • Zellin, G.1    Linde, A.2
  • 55
    • 0023664056 scopus 로고
    • Transforming Growth Factor β Is a Bifunctional Regulator of Replication and Collagen Synthesis in Osteoblast-Enriched Cell Cultures From Fetal Rat Bone
    • Centrella M, McCarthy TL, Canalis E. Transforming Growth Factor β Is a Bifunctional Regulator of Replication and Collagen Synthesis in Osteoblast-Enriched Cell Cultures From Fetal Rat Bone. J Biol Chem 1987; 262(6):2869-74.
    • (1987) J Biol Chem , vol.262 , Issue.6 , pp. 2869-2874
    • Centrella, M.1    McCarthy, T.L.2    Canalis, E.3
  • 59
    • 0033800431 scopus 로고    scopus 로고
    • Direct Stimulation of Osteoclastic Bone Resorption by Bone Morphogenetic Protein (BMP)-2 and Expression of BMP Receptors in Mature Osteoclasts
    • Kaneko H, Arakawa T, Mano H, Kaneda T, Ogasawara A, Nakagawa M, Toyama Yabe Y, Kumegawa M, Hakeda Y. Direct Stimulation of Osteoclastic Bone Resorption by Bone Morphogenetic Protein (BMP)-2 and Expression of BMP Receptors in Mature Osteoclasts. Bone 2000; 27(4):479-86.
    • (2000) Bone , vol.27 , Issue.4 , pp. 479-486
    • Kaneko, H.1    Arakawa, T.2    Mano, H.3    Kaneda, T.4    Ogasawara, A.5    Nakagawa, M.6    Toyama, Y.Y.7    Kumegawa, M.8    Hakeda, Y.9
  • 60
    • 0033609409 scopus 로고    scopus 로고
    • Bone Morphogenetic Protein-2 Enhances Osteoclast Formation Mediated by Interleukin-1alpha Through Upregulation of Osteoclast Differentiation Factor and Cyclooxygenase-2
    • Koide M, Murase Y, Yamato K, Noguchi T, Okahashi N, Nishihara T. Bone Morphogenetic Protein-2 Enhances Osteoclast Formation Mediated by Interleukin-1alpha Through Upregulation of Osteoclast Differentiation Factor and Cyclooxygenase-2. Biochem Biophys Res Commun 1999;259(1):97-102.
    • (1999) Biochem Biophys Res Commun , vol.259 , Issue.1 , pp. 97-102
    • Koide, M.1    Murase, Y.2    Yamato, K.3    Noguchi, T.4    Okahashi, N.5    Nishihara, T.6
  • 61
  • 62
    • 84857883023 scopus 로고
    • Anatomy of the Laboratory Rat. Williams & Wilkins, Baltimore
    • Hebel R, Stromberg MW. Myology. Anatomy of the Laboratory Rat.Williams & Wilkins, Baltimore; 1976.
    • (1976) Myology
    • Hebel, R.1    Stromberg, M.W.2


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