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Journal of Bone and Joint Surgery

Volumn 83, Issue 8, 2001, Pages 1219-1230

Recombinant human bone morphogenetic protein-2 accelerates healing in a rabbit ulnar osteotomy model

(8) Bouxsein, M L a Turek, T J a Blake, C A a D'Augusta, D a Li, X a Stevens, M a Seeherman, H J a Wozney, J M a

a PFIZER INC (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IODINE 125; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOMECHANICS; BONE MATURATION; CALLUS; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; FRACTURE HEALING; GAMMA SCINTIGRAPHY; MALE; NONHUMAN; OSTEOTOMY; PRIORITY JOURNAL; RABBIT;

EID: 0034910615 PISSN: 00219355 EISSN: None Source Type: Journal
DOI: 10.2106/00004623-200108000-00012 Document Type: Article

Times cited : (178)

References (64)

1
- 0033852993
- Displaced tibial shaft fractures: A prospective randomized study of closed intramedullary nailing versus cast treatment in 53 patients
- (2000) Acta Orthop Scand , vol.71 , pp. 160-167
- Karladani, A.H.¹ Granhed, H.² Edshage, B.³ Jerre, R.⁴ Styf, J.⁵

2
- 0033961081
- Outcome following nonoperative treatment of displaced distal radius fractures in low-demand patients older than 60 years
- (2000) J Hand Surg [Am] , vol.25 , pp. 19-28
- Young, B.T.¹ Rayan, G.M.²

3
- 0003913292
- Rosemont, IL: American Academy of Orthopaedic Surgeons
- (1999) Musculoskeletal conditions in the United States. 2nd ed.
- Praemer, A.¹ Furner, S.² Rice, D.³

4
- 0029314291
- Enhancement of fracture-healing
- (1995) J Bone Joint Surg Am , vol.77 , pp. 940-956
- Einhorn, T.A.¹

5
- 0031056651
- The economics of treating tibia fractures. The cost of delayed unions
- (1997) Bull Hosp Joint Dis , vol.56 , pp. 63-72
- Heckman, J.D.¹ Sarasohn-Kahn, J.²

6
- 0031734172
- Concepts of fracture union, delayed union, and nonunion
- (1998) Clin Orthop , Issue.355 SUPPL.
- Marsh, D.¹

7
- 0030229114
- Cigarette smoking and its orthopedic consequences
- (1996) Am J Orthop , vol.25 , pp. 590-597
- Kwiatkowski, T.C.¹ Hanley E.N., Jr.² Ramp, W.K.³

8
- 85060748483
- Factors that affect fracture healing
- (1997) Am J Orthop , vol.26 , pp. 1614
- Heckman, J.D.¹

9
- 0031766839
- Clinical effects of electromagnetic and electric fields on fracture healing
- (1998) Clin Orthop , Issue.355 SUPPL.
- Ryaby, J.T.¹

10
- 0031791387
- Effects of mechanical factors on the fracture healing process
- (1998) Clin Orthop , Issue.355 SUPPL.
- Claes, L.E.¹ Heigele, C.A.² Neidlinger-Wilke, C.³ Kaspar, D.⁴ Seidl, W.⁵ Margevicius, K.J.⁶ Augat, P.⁷

11
- 0031734030
- Enhancement of fracture healing by low intensity ultrasound
- (1998) Clin Orthop , Issue.355 SUPPL.
- Hadjiargyrou, M.¹ McLeod, K.² Ryaby, J.R.³ Rubin, C.⁴

12
- 0032822929
- Osteoinductive growth factors in preclinical fracture and long bone defects models
- (1999) Orthop Clin North Am , vol.30 , pp. 647-658
- Bostrom, M.R.¹ Saleh, K.J.² Einhorn, T.A.³

13
- 0030016220
- Growth factors for bone growth and repair: IGF, TGF beta and BMP
- (1996) Bone , vol.19 , Issue.1 SUPPL.
- Linkhart, T.A.¹ Mohan, S.² Baylink, D.J.³

14
- 0033430113
- The biology of fracture healing: Optimising outcome
- (1999) Br Med Bull , vol.55 , pp. 856-869
- Marsh, D.R.¹ Li, G.²

15
- 0031733871
- Expression of bone morphogenetic proteins in fracture healing
- (1998) Clin Orthop , Issue.355 SUPPL.
- Bostrom, M.R.¹

16
- 0026769957
- Regulation of fracture repair by growth factors
- (1992) Proc Soc EXp Biol Med , vol.200 , pp. 165-170
- Bolander, M.E.¹

17
- 0027410956
- Demonstration of TGF-beta 1 mRNA by in situ hybridization in normal human fracture healing
- (1993) Calcif Tissue Int , vol.52 , pp. 74-78
- Andrew, J.G.¹ Hoyland, J.² Andrew, S.M.³ Freemont, A.J.⁴ Marsh, D.⁵

18
- 0027753913
- Expression of four growth factors during fracture repair
- (1993) Int J Dev Biol , vol.37 , pp. 573-577
- Bourque, W.T.¹ Gross, M.² Hall, B.K.³

19
- 0029008655
- Immunolocalization and expression of bone morphogenitic proteins 2 and 4 in fracture healing
- (1995) J Orthop Res , vol.13 , pp. 357-367
- Bostrom, M.P.¹ Lane, J.M.² Berberian, W.S.³ Missri, A.A.⁴ Tomin, E.⁵ Weiland, A.⁶ Doty, S.B.⁷ Glaser, D.⁸ Rosen, V.M.⁹

20
- 0032575484
- Cloning of a novel cDNA expressed during the early stages of fracture healing
- (1998) Biochem Biophys Res Commun , vol.249 , pp. 879-884
- Hadjiargyrou, M.¹ Halsey, M.F.² Ahrens, W.³ Rightmire, E.P.⁴ McLeod, K.J.⁵ Rubin, C.T.⁶

21
- 0032078468
- Immunohistochemical detection of activin A, follistatin, and activin receptors during fracture healing in the rat
- (1998) J Orthop Res , vol.16 , pp. 314-321
- Nagamine, T.¹ Imamura, T.² Ishidou, Y.³ Kato, M.⁴ Murata, F.⁵ Ten Dijke, P.⁶ Sakou, T.⁷

22
- 0032731755
- Growth factor regulation of fracture repair
- (1999) J Bone Miner Res , vol.14 , pp. 1805-1815
- Barnes, G.L.¹ Kostenuik, P.J.² Gerstenfeld, L.C.³ Einhorn, T.A.⁴

23
- 0029143554
- Platelet-derived growth factor expression in normally healing human fractures
- (1995) Bone , vol.16 , pp. 455-460
- Andrew, J.G.¹ Hoyland, J.A.² Freemont, A.J.³ Marsh, D.R.⁴

24
- 0031974284
- Bone morphogenetic protein and bone morphogenetic protein gene family in bone formation and repair
- (1998) Clin Orthop , vol.346 , pp. 26-37
- Wozney, J.M.¹ Rosen, V.²

25
- 0032101214
- Bone morphogenetic proteins: From basic studies to clinical approaches
- (1998) Bone , vol.22 , pp. 591-603
- Sakou, T.¹

26
- 0032100625
- Distinct and overlapping patterns of localization of bone morphogenetic protein (BMP) family members and a BMP type II receptor during fracture healing in rats
- (1998) Bone , vol.22 , pp. 605-612
- Onishi, T.¹ Ishidou, Y.² Nagamine, T.³ Yone, K.⁴ Imamura, T.⁵ Kato, M.⁶ Sampath, T.K.⁷ Ten Dijke, P.⁸ Sakou, T.⁹

27
- 0027185702
- Bone morphogenetic protein-2 causes commitment and differentiation in C3H10T1/2 and 3T3 cells
- (1993) Growth Factors , vol.9 , pp. 57-71
- Wang, E.A.¹ Israel, D.I.² Kelly, S.³ Luxenberg, D.P.⁴

28
- 0027721063
- Expression of human bone morphogenetic proteins-2 or -4 in murine mesenchymal progenitor C3H1OT1/2 cells induces differentiation into distinct mesenchymal cell lineages
- (1993) DNA Cell Biol , vol.12 , pp. 871-880
- Ahrens, M.¹ Ankenbauer, T.² Schroder, D.³ Hollnagel, A.⁴ Mayer, H.⁵ Gross, G.⁶

29
- 0025685009
- Growth factors influencing bone development
- (1990) J Cell Sci Suppl , vol.13 , pp. 149-156
- Wozney, J.M.¹ Rosen, V.² Byrne, M.³ Celeste, A.J.⁴ Moutsatsos, I.⁵ Wang, E.A.⁶

30
- 0029882641
- Use of bone morphogenetic protein-2 in the rabbit ulnar nonunion model
- (1996) Clin Orthop , vol.327 , pp. 272-282
- Bostrom, M.¹ Lane, J.M.² Tomin, E.³ Browne, M.⁴ Berberian, W.⁵ Turek, T.⁶ Smith, J.⁷ Wozney, J.⁸ Schildhauer, T.⁹

31
- 0026757708
- The healing of segmental bone defects, induced by recombinant human bone morphogenetic protein (rhBMP-2). A radiographic, histological, and biomechanical study in rats
- erratum, 1992;74:1111
- (1992) J Bone Joint Surg Am , vol.74 , pp. 659-670
- Yasko, A.W.¹ Lane, J.M.² Fellinger, E.J.³ Rosen, V.⁴ Wozney, J.M.⁵ Wang, E.A.⁶

32
- 0031957888
- Healing bone using recombinant human bone morphogenetic protein 2 and copolymer
- (1998) Clin Orthop , vol.349 , pp. 205-217
- Kirker-Head, C.A.¹ Gerhart, T.N.² Armstrong, R.³ Schelling, S.H.⁴ Carmel, L.A.⁵

33
- 0027318019
- Healing segmental femoral defects in sheep using recombinant human bone morphogenetic protein
- (1993) Clin Orthop , vol.293 , pp. 317-326
- Gerhart, T.N.¹ Kirker-Head, C.A.² Kriz, M.J.³ Holtrop, M.E.⁴ Hennig, G.E.⁵ Hipp, J.⁶ Schelling, S.H.⁷ Wang, E.⁸

34
- 0031441929
- Bone formation with use of rhBMP-2 (recombinant human bone morphogenetic protein-2)
- (1997) J Bone Joint Surg Am , vol.79 , pp. 1778-1790
- Zegzula, H.D.¹ Buck, D.C.² Brekke, J.³ Wozney, J.M.⁴ Hollinger, J.O.⁵

35
- 0033564706
- Posterolateral lumbar intertransverse process spine arthrodesis with recombinant human bone morphogenetic protein 2/hydroxyapatite-tricalcium phosphate after laminectomy in the nonhuman primate
- (1999) Spine , vol.24 , pp. 1179-1185
- Boden, S.D.¹ Martin G.J., Jr.² Morone, M.A.³ Ugbo, J.L.⁴ Moskovitz, P.A.⁵

36
- 0031923287
- Laparoscopic anterior spinal arthrodesis with rhBMP-2 in a titanium interbody threaded cage
- (1998) J Spinal Disord , vol.11 , pp. 95-101
- Boden, S.D.¹ Martin G.J., Jr.² Horton, W.C.³ Truss, T.L.⁴ Sandhu, H.S.⁵

37
- 0033019989
- Bone morphogenetic protein-2 increases the rate of callus formation after fracture of the rabbit tibia
- (1999) Calcif Tissue Int , vol.65 , pp. 83-89
- Bax, B.E.¹ Wozney, J.M.² Ashhurst, D.E.³

38
- 0031683897
- Effect of recombinant human bone morphogenetic protein-2 on fracture healing in a goat tibial fracture model
- (1998) J Bone Miner Res , vol.13 , pp. 1483-1490
- Welch, R.D.¹ Jones, A.L.² Bucholz, R.W.³ Reinert, C.M.⁴ Tjia, J.S.⁵ Pierce, W.A.⁶ Wozney, J.M.⁷ Li, X.J.⁸

39
- 0032992531
- Characterization of rhBMP-2 pharmacokinetics implanted with biomaterial carriers in the rat ectopic model
- (1999) J Biomed Mater Res , vol.46 , pp. 193-202
- Uludag, H.¹ D'Augusta, D.² Palmer, R.³ Timony, G.⁴ Wozney, J.⁵

40
- 0033954799
- Repair of articular cartilage defects one year after treatment with recombinant human bone morphogenetic protein-2 (rhBMP-2)
- (2000) J Bone Joint Surg Am , vol.82 , pp. 151-160
- Sellers, R.S.¹ Zhang, R.² Glasson, S.S.³ Kim, H.D.⁴ Peluso, D.⁵ D'Augusta, D.A.⁶ Beckwith, K.⁷ Morris, E.A.⁸

41
- 0032773857
- rhBMP-collagen sponges as osteoinductive devices: Effects of in vitro sponge characteristics and protein pl on in vivo rhBMP pharmacokinetics
- (1999) Ann N Y Acad Sci , vol.875 , pp. 369-378
- Uludag, H.¹ Friess, W.² Williams, D.³ Porter, T.⁴ Timony, G.⁵ D'Augusta, D.⁶ Blake, C.⁷ Palmer, R.⁸ Biron, B.⁹ Wozney, J.¹⁰

42
- 0017359006
- The four biomechanical stages of fracture repair
- (1977) J Bone Joint Surg Am , vol.59 , pp. 188-192
- White, A.A.¹ Panjabi, M.M.² Southwick, W.O.³

43
- 0034455103
- Birth and death of bone cells: Basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis
- (2000) Endocr Rev , vol.21 , pp. 115-137
- Manolagas, S.C.¹

44
- 0001783646
- Bone morphogenetic proteins
- Bilezikian JP, Raisz LG, Rodan GA, editors. San Diego: Academic Press
- (1996) Principles of bone biology , pp. 661-671
- Rosen, V.¹ Cox, K.² Hattersly, G.³

45
- 0030678549
- Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation
- (1997) Cell , vol.89 , pp. 747-754
- Ducy, P.¹ Zhang, R.² Geoffroy, V.³ Ridall, A.L.⁴ Karsenty, G.⁵

46
- 0030684749
- Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
- (1997) Cell , vol.89 , pp. 755-764
- Komori, T.¹ Yagi, H.² Nomura, S.³ Yamaguchi, A.⁴ Sasaki, K.⁵ Deguchi, K.⁶ Shimizu, Y.⁷ Bronson, R.T.⁸ Gao, Y.H.⁹ Inada, M.¹⁰ Sato, M.¹¹ Okamoto, R.¹² Kitamura, Y.¹³ Yoshiki, S.¹⁴ Kishimoto, T.¹⁵

47
- 0028787830
- Enhanced expression of type I receptors for bone morphogenetic proteins during bone formation
- (1995) J Bone Miner Res , vol.10 , pp. 1651-1659
- Ishidou, Y.¹ Kitajima, I.² Obama, H.³ Maruyama, I.⁴ Murata, F.⁵ Imamura, T.⁶ Yamada, N.⁷ Ten Dijke, P.⁸ Miyazono, K.⁹ Sakou, T.¹⁰

48
- 0029704231
- Effects of periosteal stripping on healing of segmental fractures in rats
- (1996) J Orthop Trauma , vol.10 , pp. 279-284
- Utvag, S.E.¹ Grundnes, O.² Reikeras, O.³

49
- 0031946205
- Effects of lesion between bone, periosteum and muscle on fracture healing in rats
- (1998) Acta Orthop Scand , vol.69 , pp. 177-180
- Utvag, S.E.¹ Grundnes, O.² Reikeras, O.³

50
- 0034087699
- Role of fracture hematoma and periosteum during fracture healing in rats: Interaction of fracture hematoma and the periosteum in the initial step of the healing process
- (2000) J Orthop Sci , vol.5 , pp. 64-70
- Ozaki, A.¹ Tsunoda, M.² Kinoshita, S.³ Saura, R.⁴

51
- 0017750467
- Effects of compression and cyclical loading on fracture healing - A quantitative biomechanical study
- (1977) J Biomech , vol.10 , pp. 233-239
- White, A.A.¹ Panjabi, M.M.² Southwick, W.O.³

52
- 0031733643
- Potential role of bone morphogenetic proteins in fracture healing
- (1998) Clin Orthop , Issue.355 SUPPL.
- Bostrom, M.R.¹ Camacho, N.P.²

53
- 0031766406
- Potential role of fibroblast growth factor in enhancement of fracture healing
- (1998) Clin Orthop , Issue.355 SUPPL.
- Radomsky, M.L.¹ Thompson, A.Y.² Spiro, R.C.³ Poser, J.W.⁴

54
- 0031734292
- The potential role of transforming growth factor beta in fracture healing
- (1998) Clin Orthop , Issue.355 SUPPL.
- Rosier, R.N.¹ O'Keefe, R.J.² Hicks, D.G.³

55
- 0027445123
- Transforming growth factor-beta enhances fracture healing in rabbit tibiae
- (1993) Acta Orthop Scand , vol.64 , pp. 553-556
- Lind, M.¹ Schumacker, B.² Soballe, K.³ Keller, J.⁴ Melsen, F.⁵ Bunger, C.⁶

56
- 0028205108
- Local injection of TGF-beta increases the strength of tibial fractures in the rat
- (1994) Acta Orthop Scand , vol.65 , pp. 37-41
- Nielsen, H.M.¹ Andreassen, T.T.² Ledet, T.³ Oxlund, H.⁴

57
- 0029119625
- The effect of exogenous transforming growth factor-beta 2 on healing fractures in the rabbit
- (1995) Bone , vol.16 , pp. 521-527
- Critchlow, M.A.¹ Bland, Y.S.² Ashhurst, D.E.³

58
- 0031554863
- Development of tricalcium phosphate/amylopectin paste combined with recombinant human transforming growth factor beta 1 as a bone defect filler
- (1997) J Biomed Mater Res , vol.36 , pp. 295-305
- Ongpipattanakul, B.¹ Nguyen, T.² Zioncheck, T.F.³ Wong, R.⁴ Osaka, G.⁵ DeGuzman, L.⁶ Lee, W.P.⁷ Beck, L.S.⁸

59
- 0029992830
- Limited chondro-osteogenesis by recombinant human transforming growth factor-beta 1 in calvarial defects of adult baboons (Papio ursinus)
- (1996) J Bone Miner Res , vol.11 , pp. 938-945
- Ripamonti, U.¹ Bosch, C.² Van den Heever, B.³ Duneas, N.⁴ Melsen, B.⁵ Ebner, R.⁶

60
- 0027930521
- Stimulation of fracture repair by recombinant human basic fibroblast growth factor in normal and streptozotocin-diabetic rats
- (1994) Endocrinology , vol.135 , pp. 774-781
- Kawaguchi, H.¹ Kurokawa, T.² Hanada, K.³ Hiyama, Y.⁴ Tamura, M.⁵ Ogata, E.⁶ Matsumoto, T.⁷

61
- 0031781483
- Recombinant human basic fibroblast growth factor accelerates fracture healing by enhancing callus remodeling in experimental dog tibial fracture
- (1998) J Bone Miner Res , vol.13 , pp. 942-949
- Nakamura, T.¹ Hara, Y.² Tagawa, M.³ Tamura, M.⁴ Yuge, T.⁵ Fukuda, H.⁶ Nigi, H.⁷

62
- 0032816770
- Novel formulation of fibroblast growth factor-2 in a hyaluronan gel accelerates fracture healing in nonhuman primates
- (1999) J Orthop Res , vol.17 , pp. 607-614
- Radomsky, M.L.¹ Aufdemorte, T.B.² Swain, L.D.³ Fox, W.C.⁴ Spiro, R.C.⁵ Poser, J.W.⁶

63
- 0029618813
- Exogenous fibroblast growth factors-1 and -2 do not accelerate fracture healing in the rabbit
- (1995) Acta Orthop Scand , vol.66 , pp. 543-548
- Bland, Y.S.¹ Critchlow, M.A.² Ashhurst, D.E.³

64
- 0033073616
- Comparison of healing process in open osteotomy model and closed fracture model
- (1999) J Orthop Trauma , vol.13 , pp. 114-120
- Park, S.H.¹ O'Connor, K.² Sung, R.³ McKellop, H.⁴ Sarmiento, A.⁵

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